| Home | E-Submission | Sitemap | Contact Us |  
top_img
J Korean Cancer Assoc > Volume 10(1); 1975 > Article
Journal of the Korean Cancer Association 1975;10(1): 1-13.
신종 가이식성 자연발생 마우스타액선 선암 ( 윤선암 ) 의 병리조직학적소견 및 이식율에 대하여
윤탁구, 성호경
A NEW TRANSPLANTABLE MOUSE SALIVARY ADENOCARCINOMA 7108 ( YUN ADENOCARCINOMA ) OF SPONTANEOUS ORIGIN
Taik Koo Yun, Ho Kyung Sung
ABSTRACT
A very rare spontaneous transplantable salivary adenocarcimoma wss found four years ago in the right submaxillary region of a untreated male albino moase bred in Seoul area. At autopsy, tumor, 2. 0 cm. in greatest diameter, was nodular, whitish-pink- and noneneapsulated, and proved to be arisen from salivary gland. Microscopically, the tumor was of a relatively well differentiated adenocarcinoma with extensive necrosis. Thegrowth was composed of acini, cords and sheets of cells supported by thin strands of fibrous stroma. Transplantabilities to mice were 13.5% in the original albino strain, 0% in DBA/2N, 6.8% in C3HHeN, 16.4% in C3H/HeN, 22.2% in N:GP(SW), and 100% in both C57BL/6N and BDF1 hybrid. The tumor line was maintained in C57BL/6N by transfering in average every 29.7 days and average survival time of these mice was 57 days. Hence, it is believed that this new transplantable spontaneous salivary adenocarcinoma will be a suitable model for investigations in the field of experimantal oncology.
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Share:      
METRICS
1,829
View
13
Download
Related article
A NEW TRANSPLANTABLE MOUSE SALIVARY ADENOCARCINOMA 7311 ( YUN ADENOCARCINOMA ) OF SPONTANEOUS ORIGIN  1975 ;10(1)
Editorial Office
Korean Cancer Association
Room 1824, Gwanghwamun Officia
92 Saemunan-ro, Jongno-gu, Seoul 03186, Korea
TEL: +82-2-3276-2410   FAX: +82-2-792-1410   E-mail: journal@cancer.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Cancer Association.                 Developed in M2PI