Cancer Research and Treatment

ORIGINAL ARTICLE 2016 December 6 Laminin Modulates the Stem Cell Population in LM05-E Murine Breast Cancer Cells through the Activation of the MAPK/ERK Pathway
Purpose We investigated the effects of laminin on the fraction of cells with self-renewing capacity in the estrogen-dependent, tamoxifen-sensitive LM05-E breast cancer cell line. We also determined whether laminin affected the response to tamoxifen. Materials and Methods The ...

ORIGINAL ARTICLE 2016 December 12 Role of Adjuvant Thoracic Radiation Therapy and Full Dose Chemotherapy in pN2 Non-small Cell Lung Cancer: Elucidation Based on Single Institute Experience
Purpose The optimal adjuvant therapy modality for treating pN2 non-small cell lung cancer patients has not yet been established. In this study, the authors investigated clinical outcomes following three different adjuvant therapy modalities. Materials and Methods From January...

ORIGINAL ARTICLE 2017 January 18 Effect of Adjuvant Chemotherapy after Complete Resection for Pathologic Stage IB Lung Adenocarcinoma in High-Risk Patients as Defined by a New Recurrence Risk Scoring Model
Purpose We conducted a retrospective analysis to determine if adjuvant chemotherapy prolongs overall survival in patients with pathologic stage IB lung adenocarcinoma who had undergone complete resection and were defined as high-risk by a newly developed recurrence risk scoring...

ORIGINAL ARTICLE 2016 December 26 Genetic Alterations and Their Clinical Implications in High-Recurrence Risk Papillary Thyroid Cancer
Purpose Papillary thyroid carcinomas (PTCs) frequently involve genetic alterations. The objective of this study was to investigate genetic alterations and further explore the relationships between these genetic alterations and clinicopathological characteristics in a high-recurr...

Current Issue

Volume 49(4); Oct 2017

Volume 49(3); July 2017

Volume 49(2); April 2017

Review Article

851

Anti-angiogenic Therapy in Patients with Advanced Gastric and Gastroesophageal Junction Cancer: A Systematic Review

Li-Tzong Chen, Do-Youn Oh, Min-Hee Ryu, Kun-Huei Yeh, Winnie Yeo, Roberto Carlesi, Rebecca Cheng, Jongseok Kim, Mauro Orlando, Yoon-Koo Kang

Cancer Res Treat. 2017;49(4):851-868. Published online January 3, 2017 DOI: https://doi.org/10.4143/crt.2016.176

Cited By 3

Original Articles

869

Laminin Modulates the Stem Cell Population in LM05-E Murine Breast Cancer Cells through the Activation of the MAPK/ERK Pathway

Damián E. Berardi, Diego Raffo, Laura B. Todaro, Marina Simian

Cancer Res Treat. 2017;49(4):869-879. Published online December 6, 2016 DOI: https://doi.org/10.4143/crt.2016.378

880

Role of Adjuvant Thoracic Radiation Therapy and Full Dose Chemotherapy in pN2 Non-small Cell Lung Cancer: Elucidation Based on Single Institute Experience

Hyojung Park, Dongryul Oh, Yong Chan Ahn, Hongryull Pyo, Jae Myung Noh, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Jae Ill Zo, Young Mog Shim

Cancer Res Treat. 2017;49(4):880-889. Published online December 12, 2016 DOI: https://doi.org/10.4143/crt.2016.442

890

The Prognostic Values of Preoperative Tumor Volume and Tumor Diameter in T1N0 Papillary Thyroid Cancer

Seung Taek Lim, Ye Won Jeon, Young Jin Suh

Cancer Res Treat. 2017;49(4):890-897. Published online December 13, 2016 DOI: https://doi.org/10.4143/crt.2016.325

Cited By 1

898

Effect of Adjuvant Chemotherapy after Complete Resection for Pathologic Stage IB Lung Adenocarcinoma in High-Risk Patients as Defined by a New Recurrence Risk Scoring Model

Hyo Joon Jang, Sukki Cho, Kwhanmien Kim, Sanghoon Jheon, Hee Chul Yang, Dong Kwan Kim

Cancer Res Treat. 2017;49(4):898-905. Published online January 18, 2017 DOI: https://doi.org/10.4143/crt.2016.312

906

Genetic Alterations and Their Clinical Implications in High-Recurrence Risk Papillary Thyroid Cancer

Min-Young Lee, Bo Mi Ku, Hae Su Kim, Ji Yun Lee, Sung Hee Lim, Jong-Mu Sun, Se-Hoon Lee, Keunchil Park, Young Lyun Oh, Mineui Hong, Han-Sin Jeong, Young-Ik Son, Chung-Hwan Baek, Myung-Ju Ahn

Cancer Res Treat. 2017;49(4):906-914. Published online December 26, 2016 DOI: https://doi.org/10.4143/crt.2016.424

Cited By 1

915

Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies

Eun Jin Heo, Young Jae Cho, William Chi Cho, Ji Eun Hong, Hye-Kyung Jeon, Doo-Yi Oh, Yoon-La Choi, Sang Yong Song, Jung-Joo Choi, Duk-Soo Bae, Yoo-Young Lee, Chel Hun Choi, Tae-Joong Kim, Woong-Yang Park, Byoung-Gie Kim, Jeong-Won Lee

Cancer Res Treat. 2017;49(4):915-926. Published online January 4, 2017 DOI: https://doi.org/10.4143/crt.2016.322

927

Postmastectomy Radiotherapy in Patients with pT1-2N1 Breast Cancer Treated with Taxane-Based Chemotherapy: A Retrospective Multicenter Analysis (KROG 1418)

Yeon-Joo Kim, Won Park, Boram Ha, Boram Park, Jungnam Joo, Tae Hyun Kim, In Hae Park, Keun Seok Lee, Eun Sook Lee, Kyung Hwan Shin, Haeyoung Kim, Jeong Il Yu, Doo Ho Choi, Seung Jae Huh, Chan Woo Wee, Kyubo Kim, Kyung Ran Park, Yong Bae Kim, Sung Ja Ahn, Jong Hoon Lee, Jin Hee Kim, Mison Chun, Hyung-Sik Lee, Jung Soo Kim, Jihye Cha

Cancer Res Treat. 2017;49(4):927-936. Published online December 26, 2016 DOI: https://doi.org/10.4143/crt.2016.508

937

Efficacy and Safety of First-Line Necitumumab Plus Gemcitabine and Cisplatin Versus Gemcitabine and Cisplatin in East Asian Patients with Stage IV Squamous Non-small Cell Lung Cancer: A Subgroup Analysis of the Phase 3, Open-Label, Randomized SQUIRE Study

Keunchil Park, Eun Kyung Cho, Maximino Bello, Myung-Ju Ahn, Sumitra Thongprasert, Eun-Kee Song, Victoria Soldatenkova, Henrik Depenbrock, Tarun Puri, Mauro Orlando

Cancer Res Treat. 2017;49(4):937-946. Published online January 6, 2017 DOI: https://doi.org/10.4143/crt.2016.423

947

Upregulation of MicroRNA-1246 Is Associated with BRAF Inhibitor Resistance in Melanoma Cells with Mutant BRAF

Jae-Hyeon Kim, Jun-Ho Ahn, Michael Lee

Cancer Res Treat. 2017;49(4):947-959. Published online January 3, 2017 DOI: https://doi.org/10.4143/crt.2016.280

Cited By 1

960

Neurocognitive and Psychological Functioning of Children with an Intracranial Germ Cell Tumor

Younghee Park, Eun-Seung Yu, Boram Ha, Hyeon-Jin Park, Jong-Heun Kim, Joo-Young Kim

Cancer Res Treat. 2017;49(4):960-969. Published online January 4, 2017 DOI: https://doi.org/10.4143/crt.2016.204

970

Prognostic Impact of Elective Supraclavicular Nodal Irradiation for Patients with N1 Breast Cancer after Lumpectomy and Anthracycline Plus Taxane-Based Chemotherapy (KROG 1418): A Multicenter Case-Controlled Study

Haeyoung Kim, Won Park, Jeong Il Yu, Doo Ho Choi, Seung Jae Huh, Yeon-Joo Kim, Eun Sook Lee, Keun Seok Lee, Han-Sung Kang, In Hae Park, Kyung Hwan Shin, Chan Woo Wee, Kyubo Kim, Kyung Ran Park, Yong Bae Kim, Sung Ja Ahn, Jong Hoon Lee, Jin Hee Kim, Mison Chun, Hyung-Sik Lee, Jung Soo Kim, Jihye Cha

Cancer Res Treat. 2017;49(4):970-980. Published online January 4, 2017 DOI: https://doi.org/10.4143/crt.2016.382

981

Incorporating Erlotinib or Irinotecan Plus Cisplatin into Chemoradiotherapy for Stage III Non-small Cell Lung Cancer According to EGFR Mutation Status

Youngjoo Lee, Ji-Youn Han, Sung Ho Moon, Byung-Ho Nam, Kun Young Lim, Geon Kook Lee, Heung Tae Kim, Tak Yun, Hye Jin An, Jin Soo Lee

Cancer Res Treat. 2017;49(4):981-989. Published online January 6, 2017 DOI: https://doi.org/10.4143/crt.2016.522

990

Risk Factors of Female Breast Cancer in Vietnam: A Case-Control Study

Phuong Dung (Yun) Trieu, Claudia Mello-Thoms, Jennifer K. Peat, Thuan Doan Do, Patrick C. Brennan

Cancer Res Treat. 2017;49(4):990-1000. Published online February 20, 2017 DOI: https://doi.org/10.4143/crt.2016.488

1001

Randomized Phase II Study of Afatinib Plus Simvastatin Versus Afatinib Alone in Previously Treated Patients with Advanced Nonadenocarcinomatous Non-small Cell Lung Cancer

Youngjoo Lee, Ki Hyeong Lee, Geon Kook Lee, Soo-Hyun Lee, Kun Young Lim, Jungnam Joo, Yun Jung Go, Jin Soo Lee, Ji-Youn Han

Cancer Res Treat. 2017;49(4):1001-1011. Published online January 13, 2017 DOI: https://doi.org/10.4143/crt.2016.546

1012

Identification of a Novel BRCA1 Pathogenic Mutation in Korean Patients Following Reclassification of BRCA1 and BRCA2 Variants According to the ACMG Standards and Guidelines Using Relevant Ethnic Controls

Ji Soo Park, Eun Ji Nam, Hyung Seok Park, Jung Woo Han, Jung-Yun Lee, Jieun Kim, Tae Il Kim, Seung-Tae Lee

Cancer Res Treat. 2017;49(4):1012-1021. Published online January 17, 2017 DOI: https://doi.org/10.4143/crt.2016.433

Cited By 1

1022

Induction Chemotherapy with Gemcitabine and Cisplatin Followed by Simultaneous Integrated Boost–Intensity Modulated Radiotherapy with Concurrent Gemcitabine for Locally Advanced Unresectable Pancreatic Cancer: Results from a Feasibility Study

Sang Myung Woo, Min Kyeong Kim, Jungnam Joo, Kyong-Ah Yoon, Boram Park, Sang-Jae Park, Sung-Sik Han, Ju Hee Lee, Eun Kyung Hong, Yun-Hee Kim, Hae Moon, Sun-Young Kong, Tae Hyun Kim, Woo Jin Lee

Cancer Res Treat. 2017;49(4):1022-1032. Published online January 19, 2017 DOI: https://doi.org/10.4143/crt.2016.495

1033

Korean Cancer Patients’ Awareness of Clinical Trials, Perceptions on the Benefit and Willingness to Participate

Yoojoo Lim, Jee Min Lim, Won Jae Jeong, Kyung-Hun Lee, Bhumsuk Keam, Tae-Yong Kim, Tae Min Kim, Sae-Won Han, Do Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Seock-Ah Im

Cancer Res Treat. 2017;49(4):1033-1043. Published online April 7, 2017 DOI: https://doi.org/10.4143/crt.2016.413

1044

Effects of Soy Product Intake and Interleukin Genetic Polymorphisms on Early Gastric Cancer Risk in Korea: A Case-Control Study

Sarah Yang, Yoon Park, Jeonghee Lee, Il Ju Choi, Young Woo Kim, Keun Won Ryu, Joohon Sung, Jeongseon Kim

Cancer Res Treat. 2017;49(4):1044-1056. Published online January 19, 2017 DOI: https://doi.org/10.4143/crt.2016.515

1057

Gonadal and Sexual Dysfunction in Childhood Cancer Survivors

Ju Young Yoon, Hyeon Jin Park, Hee Young Ju, Jong Hyung Yoon, Jin Soo Chung, Sang Hyun Hwang, Dong Ock Lee, Hye Young Shim, Byung-Kiu Park

Cancer Res Treat. 2017;49(4):1057-1064. Published online January 25, 2017 DOI: https://doi.org/10.4143/crt.2016.197

1065

Prevalence of Mutations in Discoidin Domain-Containing Receptor Tyrosine Kinase 2 (DDR2) in Squamous Cell Lung Cancers in Korean Patients

Mi-Sook Lee, Eun Ah Jung, Sung Bin An, Yu Jin Kim, Doo-Yi Oh, Ji-Young Song, Sang-Won Um, Joungho Han, Yoon-La Choi

Cancer Res Treat. 2017;49(4):1065-1076. Published online January 25, 2017 DOI: https://doi.org/10.4143/crt.2016.347

1077

Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer

Si-Hyun Lee, Hwang-Phill Kim, Jun-Kyu Kang, Sang-Hyun Song, Sae-Won Han, Tae-You Kim

Cancer Res Treat. 2017;49(4):1077-1087. Published online January 25, 2017 DOI: https://doi.org/10.4143/crt.2016.301

1088

Can We Skip Intraoperative Evaluation of Sentinel Lymph Nodes? Nomogram Predicting Involvement of Three or More Axillary Lymph Nodes before Breast Cancer Surgery

Soo Kyung Ahn, Min Kyoon Kim, Jongjin Kim, Eunshin Lee, Tae-Kyung Yoo, Han-Byoel Lee, Young Joon Kang, Jisun Kim, Hyeong-Gon Moon, Jung Min Chang, Nariya Cho, Woo Kyung Moon, In Ae Park, Dong-Young Noh, Wonshik Han

Cancer Res Treat. 2017;49(4):1088-1096. Published online January 25, 2017 DOI: https://doi.org/10.4143/crt.2016.473

1097

Comparison of the Clinical Outcomes of Patients with Squamous Cell Carcinoma of the Tonsil Receiving Postoperative Ipsilateral Versus Bilateral Neck Radiotherapy: A Propensity Score Matching Analysis (KROG 11-07)

Youngkyong Kim, Kwan Ho Cho, Sung Ho Moon, Chang Geol Lee, Ki Chang Keum, Sang-wook Lee, Yong Chan Ahn, Dongryul Oh, Yeon-Sil Kim, Yong Kyun Won, Hong-Gyun Wu, J. Hun Hah, Young-Taek Oh

Cancer Res Treat. 2017;49(4):1097-1105. Published online February 9, 2017 DOI: https://doi.org/10.4143/crt.2016.425

1106

Survival of Cancer Patients in Northeast China: Analysis of Sampled Cancers from Population-Based Cancer Registries

Yanxia Li, Liya Yu, Jun Na, Shuang Li, Li Liu, Huijuan Mu, Xuanjuan Bi, Xiaoxia An, Xun Li, Wen Dong, Guowei Pan

Cancer Res Treat. 2017;49(4):1106-1113. Published online February 2, 2017 DOI: https://doi.org/10.4143/crt.2016.613

Cited By 1

1114

Education Level Is a Strong Prognosticator in the Subgroup Aged More Than 50 Years Regardless of the Molecular Subtype of Breast Cancer: A Study Based on the Nationwide Korean Breast Cancer Registry Database

Ki-Tae Hwang, Woochul Noh, Se-Heon Cho, Jonghan Yu, Min Ho Park, Joon Jeong, Hyouk Jin Lee, Jongjin Kim, Sohee Oh, Young A Kim, Korean Breast Cancer Society

Cancer Res Treat. 2017;49(4):1114-1126. Published online February 2, 2017 DOI: https://doi.org/10.4143/crt.2016.528

1127

Prognostic Factors and Scoring Model for Survival in Metastatic Biliary Tract Cancer

Hyung Soon Park, Ji Soo Park, You Jin Chun, Yun Ho Roh, Jieun Moon, Hong Jae Chon, Hye Jin Choi, Joon Seong Park, Dong Ki Lee, Se-Joon Lee, Dong Sup Yoon, Hei-Cheul Jeung

Cancer Res Treat. 2017;49(4):1127-1139. Published online February 6, 2017 DOI: https://doi.org/10.4143/crt.2016.538

Cited By 1

1140

Engineering of Anti-CD133 Trispecific Molecule Capable of Inducing NK Expansion and Driving Antibody-Dependent Cell-Mediated Cytotoxicity

Jörg U. Schmohl, Martin Felices, Felix Oh, Alexander J. Lenvik, Aaron M. Lebeau, Jayanth Panyam, Jeffrey S. Miller, Daniel A. Vallera

Cancer Res Treat. 2017;49(4):1140-1152. Published online February 20, 2017 DOI: https://doi.org/10.4143/crt.2016.491

Cited By 2

1153

Bilateral Salpingo-oophorectomy Compared to Gonadotropin-Releasing Hormone Agonists in Premenopausal Hormone Receptor–Positive Metastatic Breast Cancer Patients Treated with Aromatase Inhibitors

Koung Jin Suh, Se Hyun Kim, Kyung-Hun Lee, Tae-Yong Kim, Yu Jung Kim, Sae-Won Han, Eunyoung Kang, Eun-Kyu Kim, Kidong Kim, Jae Hong No, Wonshik Han, Dong-Young Noh, Maria Lee, Hee Seung Kim, Seock-Ah Im, Jee Hyun Kim

Cancer Res Treat. 2017;49(4):1153-1163. Published online February 27, 2017 DOI: https://doi.org/10.4143/crt.2016.463

1164

Practice Patterns Regarding Multidisciplinary Cancer Management and Suggestions for Further Refinement: Results from a National Survey in Korea

Yun-Gyoo Lee, Sukjoong Oh, Heejin Kimm, Dong-Hoe Koo, Do Yeun Kim, Bong-Seog Kim, Seung-Sei Lee

Cancer Res Treat. 2017;49(4):1164-1169. Published online February 22, 2017 DOI: https://doi.org/10.4143/crt.2016.517