Cancer Research and Treatment

SPECIAL ARTICLE 2016 October 18 Development of a Community-Based Palliative Care Model for Advance Cancer Patients in Public Health Centers in Busan, Korea
Purpose A feasible palliative care model for advance cancer patients is needed in Korea with its rapidly aging population and corresponding increase in cancer prevalence. This study describes the process involved in the development of a community-based palliative care (CBPC) mo...

ORIGINAL ARTICLE 2016 September 12 An Open-Label, Randomized, Parallel, Phase III Trial Evaluating the Efficacy and Safety of Polymeric Micelle-Formulated Paclitaxel Compared to Conventional Cremophor EL-Based Paclitaxel for Recurrent or Metastatic HER2-Negative Breast Cancer
Purpose Genexol-PM is a Cremophor EL–free formulation of low-molecular-weight, non-toxic, and biodegradable polymeric micelle-bound paclitaxel. We conducted a phase III study comparing the clinical efficacy and toxicity of Genexol-PM with conventional paclitaxel (Genexol). Ma...

ORIGINAL ARTICLE 2016 September 12 Real-World Treatment Patterns among Patients with Advanced Gastric Cancer in South Korea
Purpose The purpose of this study was to understand patient treatment patterns, outcomes, and healthcare resource use in cases of metastatic and/orlocally recurrent, unresectable gastric cancer (MGC) in South Korea. Materials and Methods Thirty physicians reviewed charts of e...

ORIGINAL ARTICLE 2016 September 23 Survey of Medical Oncology Status in Korea (SOMOS-K): A National Survey of Medical Oncologists in the Korean Association for Clinical Oncology (KACO)
Purpose This study was conducted to investigate the current role of medical oncologists in cancer care with a focus on increasing the recognition of medical oncology as an independent specialty. Materials and Methods Questionnaires modified from the Medical Oncology Status in...

Current Issue

Volume 49(3); Jul 2017

Volume 49(2); April 2017

Volume 49(1); January 2017

Special Article

559

Development of a Community-Based Palliative Care Model for Advance Cancer Patients in Public Health Centers in Busan, Korea

Sook-Nam Kim, Soon-Ock Choi, Seong Hoon Shin, Ji-Sun Ryu, Jeong-Won Baik

Cancer Res Treat. 2017;49(3):559-568. Published online October 18, 2016 DOI: https://doi.org/10.4143/crt.2016.276

Original Articles

569

An Open-Label, Randomized, Parallel, Phase III Trial Evaluating the Efficacy and Safety of Polymeric Micelle-Formulated Paclitaxel Compared to Conventional Cremophor EL-Based Paclitaxel for Recurrent or Metastatic HER2-Negative Breast Cancer

In Hae Park, Joo Hyuk Sohn, Sung Bae Kim, Keun Seok Lee, Joo Seop Chung, Soo Hyeon Lee, Tae You Kim, Kyung Hae Jung, Eun Kyung Cho, Yang Soo Kim, Hong Suk Song, Jae Hong Seo, Hun Mo Ryoo, Sun Ah Lee, So Young Yoon, Chul Soo Kim, Yong Tai Kim, Si Young Kim, Mi Ryung Jin, Jungsil Ro

Cancer Res Treat. 2017;49(3):569-577. Published online September 12, 2016 DOI: https://doi.org/10.4143/crt.2016.289

Cited By 4

578

Real-World Treatment Patterns among Patients with Advanced Gastric Cancer in South Korea

Gebra Cuyun Carter, Anna Kaltenboeck, Jasmina Ivanova, Astra M. Liepa, Alexandra San Roman, Maria Koh, Narayan Rajan, Rebecca Cheng, Howard G. Birnbaum, Jong Seok Kim, Yung-Jue Bang

Cancer Res Treat. 2017;49(3):578-587. Published online September 12, 2016 DOI: https://doi.org/10.4143/crt.2016.001

Cited By 1

588

Survey of Medical Oncology Status in Korea (SOMOS-K): A National Survey of Medical Oncologists in the Korean Association for Clinical Oncology (KACO)

Do Yeun Kim, Yun Gyoo Lee, Bong-Seog Kim

Cancer Res Treat. 2017;49(3):588-594. Published online September 23, 2016 DOI: https://doi.org/10.4143/crt.2016.313

595

Proton Pump Inhibition Enhances the Cytotoxicity of Paclitaxel in Cervical Cancer

Taejong Song, Hye-Kyung Jeon, Ji Eun Hong, Jung-Joo Choi, Tae-Joong Kim, Chel Hun Choi, Duk-Soo Bae, Byoung-Gie Kim, Jeong-Won Lee

Cancer Res Treat. 2017;49(3):595-606. Published online September 27, 2016 DOI: https://doi.org/10.4143/crt.2016.034

Cited By 2

607

Current Trends in the Incidence and Survival Rate of Urological Cancers in Korea

Jae Young Joung, Jiwon Lim, Chang-Mo Oh, Kyu-Won Jung, Hyunsoon Cho, Sung Han Kim, Ho Kyung Seo, Weon Seo Park, Jinsoo Chung, Kang Hyun Lee, Young-Joo Won

Cancer Res Treat. 2017;49(3):607-615. Published online September 23, 2016 DOI: https://doi.org/10.4143/crt.2016.139

Cited By 2

616

Lung Cancer Epidemiology in Korea

Aesun Shin, Chang-Mo Oh, Byung-Woo Kim, Hyeongtaek Woo, Young-Joo Won, Jin-Soo Lee

Cancer Res Treat. 2017;49(3):616-626. Published online September 23, 2016 DOI: https://doi.org/10.4143/crt.2016.178

Cited By 1

627

Clinically Significant Unclassified Variants in BRCA1 and BRCA2 Genes among Korean Breast Cancer Patients

Kyong-Ah Yoon, Boyoung Park, Byung Il Lee, Moon Jung Yang, Sun-Young Kong, Eun Sook Lee

Cancer Res Treat. 2017;49(3):627-634. Published online September 13, 2016 DOI: https://doi.org/10.4143/crt.2016.292

Cited By 1

635

Nomograms Predicting Platinum Sensitivity, Progression-Free Survival, and Overall Survival Using Pretreatment Complete Blood Cell Counts in Epithelial Ovarian Cancer

E Sun Paik, Insuk Sohn, Sun-Young Baek, Minhee Shim, Hyun Jin Choi, Tae-Joong Kim, Chel Hun Choi, Jeong-Won Lee, Byoung-Gie Kim, Yoo-Young Lee, Duk-Soo Bae

Cancer Res Treat. 2017;49(3):635-642. Published online September 27, 2016 DOI: https://doi.org/10.4143/crt.2016.282

643

Antitumor Effect of KX-01 through Inhibiting Src Family Kinases and Mitosis

Seongyeong Kim, Ahrum Min, Kyung-Hun Lee, Yaewon Yang, Tae-Yong Kim, Jee Min Lim, So Jung Park, Hyun-Jin Nam, Jung Eun Kim, Sang-Hyun Song, Sae-Won Han, Do-Youn Oh, Jee Hyun Kim, Tae-You Kim, David Hangauer, Johnson Yiu-Nam Lau, Kyongok Im, Dong Soon Lee, Yung-Jue Bang, Seock-Ah Im

Cancer Res Treat. 2017;49(3):643-655. Published online October 6, 2016 DOI: https://doi.org/10.4143/crt.2016.168

656

Long Non-coding RNA HOXA11 Antisense Promotes Cell Proliferation and Invasion and Predicts Patient Prognosis in Serous Ovarian Cancer

Ga Won Yim, Hee Jung Kim, Lee Kyung Kim, Sang Wun Kim, Sunghoon Kim, Eun Ji Nam, Young Tae Kim

Cancer Res Treat. 2017;49(3):656-668. Published online October 11, 2016 DOI: https://doi.org/10.4143/crt.2016.263

Cited By 1

669

Dose-Response Relationship between Radiation Dose and Loco-regional Control in Patients with Stage II-III Esophageal Cancer Treated with Definitive Chemoradiotherapy

Hyun Ju Kim, Yang-Gun Suh, Yong Chan Lee, Sang Kil Lee, Sung Kwan Shin, Byung Chul Cho, Chang Geol Lee

Cancer Res Treat. 2017;49(3):669-677. Published online October 6, 2016 DOI: https://doi.org/10.4143/crt.2016.354

678

ERCC1 Expression-Based Randomized Phase II Study of Gemcitabine/Cisplatin Versus Irinotecan/Cisplatin in Patients with Advanced Non-small Cell Lung Cancer

Ji-Youn Han, Geon Kook Lee, Kun Young Lim, Young Ju Lee, Byung Ho Nam, Jin Soo Lee

Cancer Res Treat. 2017;49(3):678-687. Published online October 11, 2016 DOI: https://doi.org/10.4143/crt.2016.365

688

Survey of the Patterns of Using Stereotactic Ablative Radiotherapy for Early-Stage Non-small Cell Lung Cancer in Korea

Sanghyuk Song, Ji Hyun Chang, Hak Jae Kim, Yeon Sil Kim, Jin Hee Kim, Yong Chan Ahn, Jae-Sung Kim, Si Yeol Song, Sung Ho Moon, Moon June Cho, Seon Min Youn

Cancer Res Treat. 2017;49(3):688-694. Published online October 31, 2016 DOI: https://doi.org/10.4143/crt.2016.219

695

Clinicopathologic Characteristics and Prognosis of Tongue Squamous Cell Carcinoma in Patients with and without a History of Radiation for Nasopharyngeal Carcinoma: A Matched Case-Control Study

Peng Zhang, Li Zhang, Hui Liu, Lei Zhao, Yong Li, Jing-Xian Shen, Qing Liu, Meng-Zhong Liu, Mian Xi

Cancer Res Treat. 2017;49(3):695-705. Published online October 11, 2016 DOI: https://doi.org/10.4143/crt.2016.317

706

A Multicenter Randomized Phase II Study of Docetaxel vs. Docetaxel Plus Cisplatin vs. Docetaxel Plus S-1 as Second-Line Chemotherapy in Metastatic Gastric Cancer Patients Who Had Progressed after Cisplatin Plus Either S-1 or Capecitabine

Keun-Wook Lee, Bum Jun Kim, Mi-Jung Kim, Hye Sook Han, Jin Won Kim, Young Iee Park, Sook Ryun Park

Cancer Res Treat. 2017;49(3):706-716. Published online October 18, 2016 DOI: https://doi.org/10.4143/crt.2016.216

717

Outcomes of Treatment for Malignant Peripheral Nerve Sheath Tumors: Different Clinical Features Associated with Neurofibromatosis Type 1

In Kyung Hwang, Seung Min Hahn, Hyo Sun Kim, Sang Kyum Kim, Hyo Song Kim, Kyoo‑Ho Shin, Chang Ok Suh, Chuhl Joo Lyu, Jung Woo Han

Cancer Res Treat. 2017;49(3):717-726. Published online December 1, 2016 DOI: https://doi.org/10.4143/crt.2016.271

727

Why Do Some People Choose Opportunistic Rather Than Organized Cancer Screening? The Korean National Health and Nutrition Examination Survey (KNHANES) 2010-2012

Myung-Il Hahm, Hsueh-Fen Chen, Thaddeus Miller, Liam O’Neill, Hoo-Yeon Lee

Cancer Res Treat. 2017;49(3):727-738. Published online October 31, 2016 DOI: https://doi.org/10.4143/crt.2016.243

739

Incorporating Risk Factors to Identify the Indication of Post-mastectomy Radiotherapy in N1 Breast Cancer Treated with Optimal Systemic Therapy: A Multicenter Analysis in Korea (KROG 14-23)

Hae Jin Park, Kyung Hwan Shin, Jin Ho Kim, Seung Do Ahn, Ja Young Kim, Won Park, Yong Bae Kim, Yeon-joo Kim, Jin Hee Kim, Kyubo Kim, Kyung Ran Park, Hyun Soo Shin, Bae Kwon Jeong, Sun Young Lee, Suzy Kim

Cancer Res Treat. 2017;49(3):739-747. Published online October 19, 2016 DOI: https://doi.org/10.4143/crt.2016.405

748

Effects of Postoperative Radiotherapy on Leptomeningeal Carcinomatosis or Dural Metastasis after Resection of Brain Metastases in Breast Cancer Patients

Boram Ha, Seung Yeun Chung, Yeon-Joo Kim, Ho-Shin Gwak, Jong Hee Chang, Sang Hyun Lee, In Hae Park, Keun Seok Lee, Seeyoun Lee, Tae Hyun Kim, Dae Yong Kim, Seok-Gu Kang, Chang-Ok Suh

Cancer Res Treat. 2017;49(3):748-758. Published online October 31, 2016 DOI: https://doi.org/10.4143/crt.2016.303

Cited By 1

759

Efficacy of Chemotherapy in Patients with Unresectable or Metastatic Pancreatic Acinar Cell Carcinoma: Potentially Improved Efficacy with Oxaliplatin-Containing Regimen

Changhoon Yoo, Bum Jun Kim, Kyu-pyo Kim, Jae-Lyun Lee, Tae Won Kim, Baek-Yeol Ryoo, Heung-Moon Chang

Cancer Res Treat. 2017;49(3):759-765. Published online November 9, 2016 DOI: https://doi.org/10.4143/crt.2016.371

766

FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition

Sang Hee Cho, Chang Soo Hong, Hee Nam Kim, Min Ho Shin, Ka Rham Kim, Hyun Jeong Shim, Jun Eul Hwang, Woo Kyun Bae, Ik Joo Chung

Cancer Res Treat. 2017;49(3):766-777. Published online November 9, 2016 DOI: https://doi.org/10.4143/crt.2016.457

778

Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo

Jian-Cai Tang, Rui An, Yi-Qing Jiang, Jian Yang

Cancer Res Treat. 2017;49(3):778-789. Published online November 11, 2016 DOI: https://doi.org/10.4143/crt.2015.485

790

p15^Ink4b Loss of Expression by Promoter Hypermethylation Adds to Leukemogenesis and Confers a Poor Prognosis in Acute Promyelocytic Leukemia Patients

Shahid M. Baba, Niyaz A. Azad, Zafar A. Shah, Dil-Afroze , Arshad A. Pandith, Aleem Jan, Sheikh A. Aziz

Cancer Res Treat. 2017;49(3):790-797. Published online December 5, 2016 DOI: https://doi.org/10.4143/crt.2016.108

798

Trends in Participation Rates for the National Cancer Screening Program in Korea, 2002-2012

Mina Suh, Seolhee Song, Ha Na Cho, Boyoung Park, Jae Kwan Jun, Eunji Choi, Yeol Kim, Kui Son Choi

Cancer Res Treat. 2017;49(3):798-806. Published online November 11, 2016 DOI: https://doi.org/10.4143/crt.2016.186

Cited By 1

807

CA19-9 or CEA Decline after the First Cycle of Treatment Predicts Survival in Advanced Biliary Tract Cancer Patients Treated with S-1 and Cisplatin Chemotherapy

Dae-Won Lee, Seock-Ah Im, Yu Jung Kim, Yaewon Yang, Jiyoung Rhee, Im Il Na, Kyung-Hun Lee, Tae-Yong Kim, Sae-Won Han, In Sil Choi, Do-Youn Oh, Jee Hyun Kim, Tae-You Kim, Yung-Jue Bang

Cancer Res Treat. 2017;49(3):807-815. Published online January 18, 2017 DOI: https://doi.org/10.4143/crt.2016.326

816

A Randomized Phase II Study of Leucovorin/5-Fluorouracil with or without Oxaliplatin (LV5FU2 vs. FOLFOX) for Curatively-Resected, Node-Positive Esophageal Squamous Cell Carcinoma

Sung Hee Lim, Young Mog Shim, Se Hoon Park, Hong Kwan Kim, Young Soo Choi, Myung-Ju Ahn, Keunchil Park, Jae Ill Zo, Jong-Mu Sun

Cancer Res Treat. 2017;49(3):816-823. Published online November 9, 2016 DOI: https://doi.org/10.4143/crt.2016.417

Meta-Analyses

824

Impact of Resection Margin Distance on Survival of Pancreatic Cancer: A Systematic Review and Meta-Analysis

Kyung Su Kim, Jeanny Kwon, Kyubo Kim, Eui Kyu Chie

Cancer Res Treat. 2017;49(3):824-833. Published online August 26, 2016 DOI: https://doi.org/10.4143/crt.2016.336

Cited By 2

834

Surrogate Endpoints in Second-Line Trials of Targeted Agents in Metastatic Colorectal Cancer: A Literature-Based Systematic Review and Meta-Analysis

Chiara Cremolini, Carlotta Antoniotti, Filippo Pietrantonio, Rosa Berenato, Marco Tampellini, Chiara Baratelli, Lisa Salvatore, Federica Marmorino, Beatrice Borelli, Federico Nichetti, Paolo Bironzo, Cristina Sonetto, Maria Di Bartolomeo, Filippo de Braud, Fotios Loupakis, Alfredo Falcone, Massimo Di Maio

Cancer Res Treat. 2017;49(3):834-845. Published online November 15, 2016 DOI: https://doi.org/10.4143/crt.2016.249

Case Report

846

A Rare Case of Phyllodes Tumor Metastasis to the Stomach Presenting as Anemia

Do Il Choi, Ho Seok Chi, Sang Ho Lee, Youngmee Kwon, Seog Yun Park, Sung Hoon Sim, In Hae Park, Keun Seok Lee

Cancer Res Treat. 2017;49(3):846-849. Published online September 1, 2016 DOI: https://doi.org/10.4143/crt.2016.188

Cited By 1