Cancer Research and Treatment

ORIGINAL ARTICLE 2020 June 9 Nomogram for Predicting Central Lymph Node Metastasis in Papillary Thyroid Cancer: A Retrospective Cohort Study of Two Clinical Centers
Purpose Central lymph node metastasis (CNM) are highly prevalent but hard to detect preoperatively in papillary thyroid carcinoma (PTC) patients, while the significance of prophylactic compartment central lymph node dissection (CLND) remains controversial as a treatment option....

ORIGINAL ARTICLE 2020 June 18 Protective Effects of N-Acetylcysteine against Radiation-Induced Oral Mucositis In Vitro and In Vivo
Purpose Radiation-induced oral mucositis limits delivery of high-dose radiation to targeted cancers. Therefore, it is necessary to develop a treatment strategy to alleviate radiation-induced oral mucositis during radiation therapy. We previously reported that inhibiting reacti...

ORIGINAL ARTICLE 2020 July 7 Intensity-Modulated Radiotherapy-Based Reirradiation for Head and Neck Cancer: A Multi-institutional Study by Korean Radiation Oncology Group (KROG 1707)
Purpose The benefits of reirradiation for head and neck cancer (HNC) have not been determined. This study evaluated the efficacy of reirradiation using intensity-modulated radiotherapy (IMRT) for recurrent or second primary HNC (RSPHNC) and identified subgroups for whom reirrad...

ORIGINAL ARTICLE 2020 April 23 Survival, Prognostic Factors, and Volumetric Analysis of Extent of Resection for Anaplastic Gliomas
Purpose The aim of this study is to evaluate the survival rate and prognostic factors of anaplastic gliomas according to the 2016 World Health Organization classification, including extent of resection (EOR) as measured by contrast-enhanced T1-weighted magnetic resonance imagin...

Current Issue

Volume 52(4); Oct 2020

Volume 52(3); July 2020

Volume 52(2); April 2020

Original Articles

General

993

The Fear of Cancer from the Standpoint of Oneself, the Opposite Sex and the Fear of Side Effects of Cancer Treatment

Keeho Park, Youngae Kim, Hyung Kook Yang, Hye Sook Min

Cancer Res Treat. 2020;52(4):993-1001. Published online June 24, 2020 DOI: https://doi.org/10.4143/crt.2020.285

1002

Perspectives on Professional Burnout and Occupational Stress among Medical Oncologists: A Cross-sectional Survey by Korean Society for Medical Oncology (KSMO)

Yun-Gyoo Lee, Chi Hoon Maeng, Do Yeun Kim, Bong-Seog Kim

Cancer Res Treat. 2020;52(4):1002-1009. Published online July 10, 2020 DOI: https://doi.org/10.4143/crt.2020.190

Head/neck cancer

1010

Nomogram for Predicting Central Lymph Node Metastasis in Papillary Thyroid Cancer: A Retrospective Cohort Study of Two Clinical Centers

Zheyu Yang, Yu Heng, Jianwei Lin, Chenghao Lu, Dingye Yu, Lei Tao, Wei Cai

Cancer Res Treat. 2020;52(4):1010-1018. Published online June 9, 2020 DOI: https://doi.org/10.4143/crt.2020.254

1019

Protective Effects of N-Acetylcysteine against Radiation-Induced Oral Mucositis In Vitro and In Vivo

Haeng Jun Kim, Sung Un Kang, Yun Sang Lee, Jeon Yeob Jang, Hami Kang, Chul-Ho Kim

Cancer Res Treat. 2020;52(4):1019-1030. Published online June 18, 2020 DOI: https://doi.org/10.4143/crt.2020.012

1031

Intensity-Modulated Radiotherapy-Based Reirradiation for Head and Neck Cancer: A Multi-institutional Study by Korean Radiation Oncology Group (KROG 1707)

Jeongshim Lee, Tae Hyung Kim, Yeon-Sil Kim, Myungsoo Kim, Jae Won Park, Sung Hyun Kim, Hyun Ju Kim, Chang Geol Lee

Cancer Res Treat. 2020;52(4):1031-1040. Published online July 7, 2020 DOI: https://doi.org/10.4143/crt.2020.310

Central nervous system

1041

Survival, Prognostic Factors, and Volumetric Analysis of Extent of Resection for Anaplastic Gliomas

Je Beom Hong, Tae Hoon Roh, Seok-Gu Kang, Se Hoon Kim, Ju Hyung Moon, Eui Hyun Kim, Sung Soo Ahn, Hye Jin Choi, Jaeho Cho, Chang-Ok Suh, Jong Hee Chang

Cancer Res Treat. 2020;52(4):1041-1049. Published online April 23, 2020 DOI: https://doi.org/10.4143/crt.2020.057

1050

Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma

Bo Li, Wenyi Lv, Chunde Li, Jiongxian Yang, Jiajia Chen, Jin Feng, Li Chen, Zhenyu Ma, Youqi Li, Jiayi Wang, Yanwei Liu, Yanong Li, Shuai Liu, Shiqi Luo, Xiaoguang Qiu

Cancer Res Treat. 2020;52(4):1050-1058. Published online July 9, 2020 DOI: https://doi.org/10.4143/crt.2020.437

Cited By 1

Breast cancer

1059

Real-World Data of Pyrotinib-Based Therapy in Metastatic HER2-Positive Breast Cancer: Promising Efficacy in Lapatinib-Treated Patients and in Brain Metastasis

Ying Lin, Mingxi Lin, Jian Zhang, Biyun Wang, Zhonghua Tao, Yiqun Du, Sheng Zhang, Jun Cao, Leiping Wang, Xichun Hu

Cancer Res Treat. 2020;52(4):1059-1066. Published online April 24, 2020 DOI: https://doi.org/10.4143/crt.2019.633

1067

Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression

Zhiqi Huang, Xingyu Li, Tian Xie, Changjiang Gu, Kan Ni, Qingqing Yin, Xiaolei Cao, Chunhui Zhang

Cancer Res Treat. 2020;52(4):1067-1083. Published online May 8, 2020 DOI: https://doi.org/10.4143/crt.2020.187

Cited By 1

1084

β1,4-Galactosyltransferase V Modulates Breast Cancer Stem Cells through Wnt/β-catenin Signaling Pathway

Wei Tang, Meng Li, Xin Qi, Jing Li

Cancer Res Treat. 2020;52(4):1084-1102. Published online May 27, 2020 DOI: https://doi.org/10.4143/crt.2020.093

Cited By 1

1103

Challenge for Diagnostic Assessment of Deep Learning Algorithm for Metastases Classification in Sentinel Lymph Nodes on Frozen Tissue Section Digital Slides in Women with Breast Cancer

Young-Gon Kim, In Hye Song, Hyunna Lee, Sungchul Kim, Dong Hyun Yang, Namkug Kim, Dongho Shin, Yeonsoo Yoo, Kyowoon Lee, Dahye Kim, Hwejin Jung, Hyunbin Cho, Hyungyu Lee, Taeu Kim, Jong Hyun Choi, Changwon Seo, Seong il Han, Young Je Lee, Young Seo Lee, Hyung-Ryun Yoo, Yongju Lee, Jeong Hwan Park, Sohee Oh, Gyungyub Gong

Cancer Res Treat. 2020;52(4):1103-1111. Published online June 30, 2020 DOI: https://doi.org/10.4143/crt.2020.337

Lung cancer

1112

Real-World Experience of Nivolumab in Non-small Cell Lung Cancer in Korea

Sun Min Lim, Sang-We Kim, Byoung Chul Cho, Jin Hyung Kang, Myung-Ju Ahn, Dong-Wan Kim, Young-Chul Kim, Jin Soo Lee, Jong-Seok Lee, Sung Yong Lee, Keon Uk Park, Ho Jung An, Eun Kyung Cho, Tae Won Jang, Bong-Seog Kim, Joo-Hang Kim, Sung Sook Lee, Im-II Na, Seung Soo Yoo, Ki Hyeong Lee

Cancer Res Treat. 2020;52(4):1112-1119. Published online May 15, 2020 DOI: https://doi.org/10.4143/crt.2020.245

1120

Genetic Alterations in Preinvasive Lung Synchronous Lesions

Soyeon Ahn, Jisun Lim, Soo Young Park, Hyojin Kim, Hyun Jung Kwon, Yeon Bi Han, Choon-Taek Lee, Sukki Cho, Jin-Haeng Chung

Cancer Res Treat. 2020;52(4):1120-1134. Published online June 5, 2020 DOI: https://doi.org/10.4143/crt.2020.307

Gastrointestinal cancer

1135

A Phase II Study of Avelumab Monotherapy in Patients with Mismatch Repair–Deficient/Microsatellite Instability–High or POLE-Mutated Metastatic or Unresectable Colorectal Cancer

Jwa Hoon Kim, Sun Young Kim, Ji Yeon Baek, Yong Jun Cha, Joong Bae Ahn, Han Sang Kim, Keun-Wook Lee, Ji-Won Kim, Tae-You Kim, Won Jin Chang, Joon Oh Park, Jihun Kim, Jeong Eun Kim, Yong Sang Hong, Yeul Hong Kim, Tae Won Kim

Cancer Res Treat. 2020;52(4):1135-1144. Published online April 24, 2020 DOI: https://doi.org/10.4143/crt.2020.218

Cited By 1

1145

Evaluation of the American Joint Committee on Cancer (AJCC) 8th Edition Staging System for Hepatocellular Carcinoma in 1,008 Patients with Curative Resection

Sujin Park, Sangjoon Choi, Yoon Ah Cho, Dong Hyun Sinn, Jong Man Kim, Cheol-Keun Park, Sang Yun Ha

Cancer Res Treat. 2020;52(4):1145-1152. Published online April 28, 2020 DOI: https://doi.org/10.4143/crt.2020.208

1153

A Multi-cohort Study of the Prognostic Significance of Microsatellite Instability or Mismatch Repair Status after Recurrence of Resectable Gastric Cancer

Ji Yeong An, Yoon Young Choi, Jeeyun Lee, Woo Jin Hyung, Kyoung-Mee Kim, Sung Hoon Noh, Min-Gew Choi, Jae-Ho Cheong

Cancer Res Treat. 2020;52(4):1153-1161. Published online May 4, 2020 DOI: https://doi.org/10.4143/crt.2020.173

Cited By 2

1162

FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition

Yanwei Ye, Jie Li, Dongbao Jiang, Jingjing Li, Chuangfeng Xiao, Yingze Li, Chao Han, Chunlin Zhao

Cancer Res Treat. 2020;52(4):1162-1177. Published online May 25, 2020 DOI: https://doi.org/10.4143/crt.2020.138

1178

Adjuvant Chemotherapy in Microsatellite Instability–High Gastric Cancer

Jin Won Kim, Sung-Yup Cho, Jeesoo Chae, Ji-Won Kim, Tae-Yong Kim, Keun-Wook Lee, Do-Youn Oh, Yung-Jue Bang, Seock-Ah Im

Cancer Res Treat. 2020;52(4):1178-1187. Published online June 11, 2020 DOI: https://doi.org/10.4143/crt.2020.313

1188

Tumor Control and Overall Survival after Stereotactic Body Radiotherapy for Pulmonary Oligometastases from Colorectal Cancer: A Meta-Analysis

Hoon Sik Choi, Bae Kwon Jeong, Ki Mun Kang, Hojin Jeong, Jin Ho Song, In Bong Ha, Oh-Young Kwon

Cancer Res Treat. 2020;52(4):1188-1198. Published online July 21, 2020 DOI: https://doi.org/10.4143/crt.2020.402

1199

High Systemic Inflammation Response Index (SIRI) Indicates Poor Outcome in Gallbladder Cancer Patients with Surgical Resection: A Single Institution Experience in China

Lejia Sun, Wenmo Hu, Meixi Liu, Yang Chen, Bao Jin, Haifeng Xu, Shunda Du, Yiyao Xu, Haitao Zhao, Xin Lu, Xinting Sang, Shouxian Zhong, Huayu Yang, Yilei Mao

Cancer Res Treat. 2020;52(4):1199-1210. Published online July 21, 2020 DOI: https://doi.org/10.4143/crt.2020.303

Gynecologic cancer

1211

Early Assessment of Response to Neoadjuvant Chemotherapy with ¹⁸F-FDG-PET/CT in Patients with Advanced-Stage Ovarian Cancer

Young Shin Chung, Hyun-Soo Kim, Jung-Yun Lee, Won Jun Kang, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim

Cancer Res Treat. 2020;52(4):1211-1218. Published online April 28, 2020 DOI: https://doi.org/10.4143/crt.2019.506

1219

Evaluation of Circulating Tumor DNA in Patients with Ovarian Cancer Harboring Somatic PIK3CA or KRAS Mutations

Aiko Ogasawara, Taro Hihara, Daisuke Shintani, Akira Yabuno, Yuji Ikeda, Kenji Tai, Keiichi Fujiwara, Keisuke Watanabe, Kosei Hasegawa

Cancer Res Treat. 2020;52(4):1219-1228. Published online May 6, 2020 DOI: https://doi.org/10.4143/crt.2019.688

Cited By 1

1229

Germline and Somatic BRCA1/2 Gene Mutational Status and Clinical Outcomes in Epithelial Peritoneal, Ovarian, and Fallopian Tube Cancer: Over a Decade of Experience in a Single Institution in Korea

Se Ik Kim, Maria Lee, Hee Seung Kim, Hyun Hoon Chung, Jae-Weon Kim, Noh Hyun Park, Yong-Sang Song

Cancer Res Treat. 2020;52(4):1229-1241. Published online July 27, 2020 DOI: https://doi.org/10.4143/crt.2020.557

Genitourinary cancer

1242

Cause of Mortality after Radical Prostatectomy and the Impact of Comorbidity in Men with Prostate Cancer: A Multi-institutional Study in Korea

Sahyun Pak, Dalsan You, In Gab Jeong, Dong-Eun Lee, Sung Han Kim, Jae Young Joung, Kang-Hyun Lee, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn

Cancer Res Treat. 2020;52(4):1242-1250. Published online July 3, 2020 DOI: https://doi.org/10.4143/crt.2020.286

Pediatric malignancy

1251

Genome-Wide Association Study for the Identification of Novel Genetic Variants Associated with the Risk of Neuroblastoma in Korean Children

Joon Seol Bae, Ji Won Lee, Jung Eun Yoo, Je-Gun Joung, Keon Hee Yoo, Hong Hoe Koo, Yun-Mi Song, Ki Woong Sung

Cancer Res Treat. 2020;52(4):1251-1261. Published online June 30, 2020 DOI: https://doi.org/10.4143/crt.2020.140

Lymphoma

1262

Increasing Incidence of B-Cell Non-Hodgkin Lymphoma and Occurrence of Second Primary Malignancies in South Korea: 10-Year Follow-up Using the Korean National Health Information Database

Jin Seok Kim, Yanfang Liu, Kyoung Hwa Ha, Hong Qiu, Lee Anne Rothwell, Hyeon Chang Kim

Cancer Res Treat. 2020;52(4):1262-1272. Published online May 4, 2020 DOI: https://doi.org/10.4143/crt.2020.089

1273

Forkhead Box C1 (FOXC1) Expression in Stromal Cells within the Microenvironment of T and NK Cell Lymphomas: Association with Tumor Dormancy and Activation

Ji Hae Nahm, Woo Ick Yang, Sun Och Yoon

Cancer Res Treat. 2020;52(4):1273-1282. Published online July 3, 2020 DOI: https://doi.org/10.4143/crt.2020.032

Case Reports

1283

Seminal Vesicle Involvement by Carcinoma In Situ of the Bladder: Clonal Analysis Using Next-Generation Sequencing to Elucidate the Mechanism of Tumor Spread

Hyun Sik Park, Hyun Bin Shin, Myung-Shin Lee, Joo Heon Kim, Seon-Young Kim, Jinsung Park

Cancer Res Treat. 2020;52(4):1283-1287. Published online March 19, 2020 DOI: https://doi.org/10.4143/crt.2020.002

1288

EGFR C797S as a Resistance Mechanism of Lazertinib in Non-small Cell Lung Cancer with EGFR T790M Mutation

Sehhoon Park, Bo Mi Ku, Hyun Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Se-Hoon Lee, Keunchil Park, Myung-Ju Ahn

Cancer Res Treat. 2020;52(4):1288-1290. Published online June 22, 2020 DOI: https://doi.org/10.4143/crt.2020.278

1291

Crohn’s Disease Following Rituximab Treatment for Follicular Lymphoma in a Patient with Synchronous Gastric Signet Ring Cells Carcinoma: A Case Report and Literature Review

Elisabetta Cavalcanti, Raffaele Armentano, Ivan Lolli

Cancer Res Treat. 2020;52(4):1291-1295. Published online July 13, 2020 DOI: https://doi.org/10.4143/crt.2020.406

1297

Tables of Contents (Vol. 52, No. 1~4, 2020)

Cancer Res Treat. 2020;52(4):1297-1305.

1306

Acknowledgment of Reviewers (2020)

Cancer Res Treat. 2020;52(4):1306-1309.