1Department of Internal Medicine, Seoul National University, Medical College, Seoul, Korea. 2Department of Neurosurgery, Seoul National University, Medical College, Seoul, Korea.
ABSTRACT
Solitary plasmacytoma consists of solitary bone plasmacytoma (SBP) and extramedullary plasmacytoma. Its frequency is about 7% among the total plasma cell neoplasm. Solitary bone plasmacytoma of the cranial cavity occurs in 0~18% of patients with SBP. We experienced a case of SBP originated from the middle cranial fossa in a 68-year-old man. After surgical removal of the mass, biopsy specimen revealed plasmacytoma, kappa type. There was no evidence of systemic involvement. Additional radiotherapy was performed.
Twenty-one months after the diagnosis of SBP, pathologic fracture of the left humerus happened. Biopsy specimen of the operation revealed same diagnosis. At that time, Bence Jones proteinuria was detected in immuno-electrophoresis of urine and simple bone X-rays showed multiple osteolytic lesions.A case of SBP of the orbit and middle cranial fossa in a 68-year-old man is presented and the literature is reviewed.
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