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J Korean Cancer Assoc > Volume 27(4); 1995 > Article
Journal of the Korean Cancer Association 1995;27(4): 696-703.
Multicentric Castleman 병 1 예
송용호, 황선호, 이재용, 김인순, 안유현, 김호중, 고영혜
A case of Multicentric Castleman's Disease
Yong Ho Song, Seon Ho Hwang, Jae Woong Lee, In Soon Kim, You Hern Ahn, Ho Joong Kim, Young Hyeh Ko
Multicentric Castleman's disease is a systemic lymphoproliferative disorder, characterized by generalized lymphadenopathe, multisystem involvement, disordered immunity and an in- creased incidence of malignant tumors, particularly Kaposis sarcoma and lymphoid neoplasia. The clinical presentation and laboratory features of this syndrome are similar to those of an- other atypical lymphorliferative disorder, angioimmunoblastic lymphadenopathy with dysproteinemia, although this is histologically different from Castleman's disease. A 21-year old male presented ta us with complaints of arthralgia and myalgia of 4 months duration, followed by 2weeks of high fever. Initial physical findings showed small, generalized lymphadenopathies in cervical, axillary and inguinal areas. He developed hepatosplenomegaly and pleuropericardial effusions rapidly. Lymph node biopsy from left inguinal area was consistent with angiofollicular lymph node hyperplasia, plasma cell type.
Key words: Castlemans disease, Angiofollicular lymph node hyperplasia, Angioimmunoblastic lymphadenopathy with dysproteinemia(AILD)
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