| 유방암에서 CMF 보조화학요법후 예후에 영향을 주는 전이 액와 임파절 수의 평가 |
| 임호영, 유효민, 고은희, 유내춘, 김주항, 노재경, 김병수, 이경식, 조인성 |
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| Identification of Number of Positive Axillary Nodes to Influence Prognosis in Breast Cancer after Adjuvant CMF Chemotherapy |
| Ho Yeong Lim, Hyo Min Yoo, Eun Hee Koh, Nae Chun Yoo, Joo Hang Kim, Jae Kyung Roh, Byung Soo Kim, Kyung Shik Lee, In Sung Cho |
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| ABSTRACT |
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The most important prognostic indicator for patients with operable breast cancer is the histological involvement of axillary lymph nodes metastasis, and the extent of nodal metastasis is highly prognostic, larger numbers of positive nodes are associated poorer prognosis. One hundred and nine patients of resected breast cancer with nodal involvement treated at Yonsei University College of Medicine from Dec. 1980 to Dec. 19S9 weres studied to identify the number of positive axillary nodes to influence prognosis after adjuvant CMF chemotherapy. And we obtained the following results. There was no significant difference in the disease free survival and overall survival between those with 1-3 positive axillary nodes and those with 4-7 positive nodes. So, we tried to reas- sess positive nodal groupings for determining the prognosis of breast cancer and identifying high risk group according to their nodal status. The current results showed that there was a significant difference in the disease free survival and overall survival between those with 1-7 positive axillary nodes and those with >= 8 positive nodes(DFS; 73% vs. 42%, OS; 78% vs. 40%, p < 0.05). This resport emphasizes the prognostic importance of positive nodal involvement with pa- tients of breast cancer and necessity of intensive managment for those with >= 8 positive nodes. |
| Key words:
Number of positive axillary nodes, Breast cancer, prognosis |
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