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J Korean Cancer Assoc > Volume 30(1); 1998 > Article
Journal of the Korean Cancer Association 1998;30(1): 72-79.
Pancreaticoduodenectomy for gastric Cancer
Jae Cheol Byun, Joo Ho Lee, Hang Jong Yu, Soo Jin Kim, Kuhn Uk Lee, Jin Pok Kim
Department of Surgery, Seoul National University, College of Medicine.
We purpose of this retrospective study is to evaluate the role of pancreaticoduadenectomy (PD) in gastric cancer which invades neighboring organs.
We analysed 28 patients with locally advanced gastric cancer which invaded to pancreas and/or duodenum who received surgical resection from Jan. 1989 to Dec. 1996. Patients were divided into two groups: Group A (n=12) who received PD and Group B (n=16) who received gastrectomy only. Indication of PD in group A is locally advanced gastric cancer which invaded to pancreas and/or duodenum but had no evidence of widespread nodal involvement, extended hepatic metastasis, or peritoneal dissemination.
The operation time, amount of blood loss during operation, and postoperative hospital stay were greater in group A than in group B. Operative mortality was found in 1 case in group B but none in group A. Postoperative complications were similar in both groups. Four patients had liver metastases in both group during follow up period, whereas 2 and 4 patients had disseminated peritoneal seeding in group A and B, respectively. When survival rates were compared, Group A shows better survival than Group B (p= 0.043).
These results suggest that PD is a rational and safe method for treatment of gastric cancer infiltrating into pancreatic head and/or duodenum.
Key words: Gastric cancer;Pancreaticoduodenectomy
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