Skip Navigation
Skip to contents

Cancer Res Treat : Cancer Research and Treatment

Search
Advanced Search
OPEN ACCESS
mobile search button mobile menu button

Search

Page Path
HOME > Search
21 "Cohort"
Filter
Filter
Article category
Keywords
More +
Publication year
More +
Authors
More +
Funded articles
More +
Original Articles
Association of Pro-inflammatory Cytokines with Gastric Cancer Risk: A Case-Cohort Study
Seungju Baek, Eunjung Park, Eun Young Park
Received July 29, 2024  Accepted November 18, 2024  Published online November 19, 2024  
DOI: https://doi.org/10.4143/crt.2024.718    [Accepted]
AbstractAbstract PDF
Purpose
This study aimed to assess the association between inflammatory cytokines and the risk of gastric cancer (GC).
Materials and Methods
We conducted a case-cohort study using Korean National Cancer Center Community (KNCCC) cohort data to investigate the associations between pro-inflammatory, anti-inflammatory cytokines, inflammatory mediators, and GC risk in the Korean general population (GC cases: n=159, subcohort: n=822). Serum levels of inflammatory cytokines were measured using Quantikine® ELISA and analyzed using a Cox proportional hazards regression model.
Results
Compared to those with the lowest serum interleukin 6 (IL-6) levels, the risk of GC significantly increased in the second (HR: 3.48 [1.73-6.99]), third (HR: 3.74 [1.91-7.29], and fourth quartiles (HR: 3.79 [1.93-7.48]). Elevated levels of interleukin 1β (IL-1β) (HR: 1.57 [1.12-2.21]) and interferon gamma (IFN-γ) (HR: 2.49 [1.73-3.58]) were also associated with an increased risk of GC.
Conclusion
The findings of this study indicate associations between pro-inflammatory cytokines (IL-6, IL-1β, and IFN-γ) and the risk of GC, suggesting that regulating these cytokine levels may aid in GC prevention.
  • 221 View
  • 21 Download
Close layer
Effectiveness and Safety of Regorafenib and TAS-102 in Patients with Metastatic Colorectal Cancer: A Nationwide Population-Based Study in Taiwan
Ya-Wen Chang, Chun-Nan Kuo, Chia-Lun Chang, Jason C. Hsu, Yu Ko
Received April 16, 2024  Accepted November 16, 2024  Published online November 18, 2024  
DOI: https://doi.org/10.4143/crt.2024.376    [Accepted]
AbstractAbstract PDF
Purpose
This study aimed to examine the real-world effectiveness and safety of regorafenib and trifluridine/tipiracil (TAS-102) in metastatic colorectal cancer (mCRC) patients in Taiwan.
Materials and Methods
Data were extracted from Taiwan’s National Health Insurance Research Database to evaluate the clinical outcomes of mCRC patients treated with either regorafenib or TAS-102 between 2016 and 2019. Overall survival (OS) was compared using Kaplan-Meier curves and Cox’s proportional hazard models, adjusting for age, gender, Quan-CCI score, liver metastases, number of metastatic sites, and the use of anti-EGFR medications. Additionally, OS was compared between regorafenib monotherapy and TAS-102 monotherapy, excluding patients who had received both regorafenib and TAS-102.
Results
A total of 2,608 patients in the regorafenib group and 521 patients in the TAS-102 group were identified. The median OS was 6.5 months for regorafenib and 7.5 months for TAS-102, with a significant difference observed (p=0.001). The mean duration of treatment was similar for regorafenib and TAS-102 (108 days vs. 101 days) with no significant difference. The safety profiles of the two drugs were distinct; a higher proportion of patients in the regorafenib group had hypertension and hand-foot skin reaction while nausea and vomiting were more common in the TAS-102 group. In the subgroup analysis, patients receiving TAS-102 monotherapy showed significantly longer OS than those receiving regorafenib monotherapy.
Conclusion
The findings of this study indicated that TAS-102 had superior survival outcomes compared to regorafenib in mCRC patients. This study provides insights into the effectiveness and safety profiles of regorafenib and TAS-102 in Taiwan.
  • 315 View
  • 45 Download
Close layer
Genitourinary cancer
Physical Activity and Bladder Cancer Risk: Findings of the Japan Collaborative Cohort Study
Hang An, Keyang Liu, Kokoro Shirai, Ryo Kawasaki, Akiko Tamakoshi, Hiroyasu Iso
Cancer Res Treat. 2024;56(2):616-623.   Published online October 6, 2023
DOI: https://doi.org/10.4143/crt.2023.962
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The association of physical activity with the risk of bladder cancer remains inconsistent among Asian populations. We aimed to examine the association in a large Japanese cohort.
Materials and Methods
In a population-based prospective cohort study, a total of 50,374 Japanese adults aged 40-79 years without a history of cancer or cardiovascular disease who had information on physical activity from self-administrated questionnaires were used for analysis. We performed Cox proportional hazard models to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for incident bladder cancer after adjusting for several potential confounders.
Results
During the median 17.5 years of follow-up, 153 incident bladder cancers (116 men and 37 women) were identified. After the multivariable adjustment, HRs (95% CI) of bladder cancer concerning those with recreational sports participation of 1-2 hr/wk, 3-4 hr/wk, and 5 hr/wk and more were 0.67 (0.38-1.20), 0.79 (0.36-1.74), and 0.28 (0.09-0.89), respectively (p for trend=0.017). Compared with mostly sitting at the workplace, occupational physical activity of standing and walking were associated with a lower risk of bladder cancer (HR, 0.53 [95% CI, 0.32 to 0.85]). Hours of daily walking were not associated with the risk. The lower risk of bladder cancer was more evident for recreational sports (HR, 0.33 [95% CI, 0.10 to 1.00]), and for occupational standing and walking activity at work (HR, 0.57 [95% CI, 0.33 to 0.98]) among men.
Conclusion
Recreational sports participation and occupational physical activity were inversely associated with the risk of bladder cancer among Japanese, especially in men.
  • 3,983 View
  • 178 Download
Close layer
Breast cancer
Impact of Social Support during Diagnosis and Treatment on Disease Progression in Young Patients with Breast Cancer: A Prospective Cohort Study
Danbee Kang, Seri Park, Hyo Jung Kim, Seok Won Kim, Jeong Eon Lee, Jonghan Yu, Se Kyung Lee, Ji-Yeon Kim, Seok Jin Nam, Juhee Cho, Yeon Hee Park
Cancer Res Treat. 2024;56(1):125-133.   Published online September 4, 2023
DOI: https://doi.org/10.4143/crt.2023.673
AbstractAbstract PDFPubReaderePub
Purpose
We evaluated the association between changes in social support after cancer treatment and recurrence-free survival (RFS) in such patients using a prospective cohort study.
Materials and Methods
Data were obtained from a prospective cohort study (NCT03131089) conducted at Samsung Medical Center (2013-2021). The primary outcome measure was RFS. Social support was measured using the social and family well-being (SFWB) domain of the Functional Assessment of Cancer Therapy-General. We calculated the changes in SFWB scores before and during treatment and the hazard ratio for RFS by comparing such changes.
Results
The mean±standard deviation (SD) age of the patients was 35±3.9 years, and 71.5% and 64.8% of the patients were married and had children, respectively. The mean±SD SFWB score at baseline was 20.5±5.0 out of 26. After cancer treatment, 35.9%, 10.3%, and 53.8% of the participants had increasing, unchanged, and decreasing SFWB scores, respectively. The decreasing SFWB score group had a higher risk of mortality or recurrence than the increasing group. Risk factors for the decreasing score were the presence of children during diagnosis.
Conclusion
In this cohort, changes in social support after treatment were associated with RFS in young patients with breast cancer. Health professionals should develop family interventions to help them receive proper social support.
  • 3,072 View
  • 204 Download
Close layer
Gastrointestinal cancer
Association between Metabolically Healthy Status and Risk of Gastrointestinal Cancer
Haozhe Cui, Fei Tian, Yongliang Chen, Xiangming Ma
Cancer Res Treat. 2024;56(1):238-246.   Published online August 2, 2023
DOI: https://doi.org/10.4143/crt.2023.539
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
Although obesity is associated with numerous diseases, the risks of disease may depend on metabolically healthy status. Nevertheless, it is unclear to whether metabolically healthy status affects risk of gastrointestinal (GI) cancer in general Chinese population.
Materials and Methods
A total of 114,995 participants who met the criteria were included from the Kailuan Study. The study participants were divided into four groups according to body mass index (BMI)/waist circumference (WC) and metabolic status. Incident of GI cancer (esophageal cancer, gastric cancer, liver cancer, biliary cancer, pancreatic cancer, and colorectal cancer) during 2006-2020 were confirmed by review of medical records. The Cox proportional hazard regression models were used to assess the association metabolically healthy status with the risk of GI cancer by calculating the hazard ratios (HR) and 95% confidence interval (CI).
Results
During a mean 13.76 years of follow-up, we documented 2,311 GI cancers. Multivariate Cox regression analysis showed that compared with the metabolically healthy normal-weight group, metabolically healthy obese (MHO) participants demonstrated an increased risk of developing GI cancer (HR, 1.54; 95% CI, 1.11 to 2.13) by BMI categories. However, such associations were not found for WC category. These associations were moderated by age, sex, and anatomical site of the tumor. Individuals with metabolic unhealthy normal-weight or metabolic unhealthy obesity phenotype also have an increased risk of GI cancer.
Conclusion
MHO phenotype was associated with increased risk of GI cancer. Moreover, individuals who complicated by metabolic unhealthy status have an increased risk of developing GI cancer. Hence, clinicians should consider the risk of incident GI cancer in people with abnormal metabolically healthy status and counsel them about metabolic fitness and weight control.

Citations

Citations to this article as recorded by  
  • Association between transitions in metabolic health and colorectal cancer across categories of body size phenotype: a prospective cohort study
    Qian Liu, Fei Si, Yuntao Wu, Jing Yu
    Obesity.2024; 32(10): 1948.     CrossRef
  • Gastric Cancer - Epidemiology, Modifiable and Non-modifiable Risk Factors, Challenges and Opportunities: An Updated Review
    Tajul Islam Mamun, Sabrina Younus, Md. Hashibur Rahman
    Cancer Treatment and Research Communications.2024; : 100845.     CrossRef
  • 3,046 View
  • 170 Download
  • 3 Web of Science
  • 2 Crossref
Close layer
Descriptive Analysis of Gastric Cancer Mortality in Korea, 2000-2020
Tung Hoang, Hyeongtaek Woo, Sooyoung Cho, Jeeyoo Lee, Sayada Zartasha Kazmi, Aesun Shin
Cancer Res Treat. 2023;55(2):603-617.   Published online September 6, 2022
DOI: https://doi.org/10.4143/crt.2022.307
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
This study aimed to examine secular trends, age-period-cohort effects, and geographical differences in gastric cancer (GC) mortality in Korea.
Materials and Methods
Using cause of death data from the Korean Statistical Information Service for GC from 2000 to 2020, we calculated average annual percentage changes (AAPCs) in the age-standardized mortality of GC in 17 cities and provinces through joinpoint regression. Decomposition of age, period, and cohort effects on GC mortality were elucidated by applying a log-linear model and an intrinsic estimate method. Spatial patterns and the degree of spatial clustering in 250 administrative regions were explored via Moran’s I statistics. Stratification by sex was performed for all analyses.
Results
The age-standardized mortality of GC per 100,000 persons declined from 29.0 in 2000 to 7.9 in 2020 (AAPC, -6.28%). Age-period-cohort analyses of GC mortality showed a downward trend among five-year age groups from age 20-89 years across five-year periods from 2005-2020 and five-year birth cohorts from 1920-2000. Overall, the younger birth cohort showed lower mortality rates than the older cohort within the same period. In 2020, clusters of high GC mortality were observed in the central area for men (Chungcheongbuk, Jeollabuk, Gyeongsangbuk, and Gyeongsangnam) and in the eastern area for women (Gyeongsangbuk).
Conclusion
This study identified a downward trend in GC mortality among men and women from 2000 to 2020 in Korea. This trend was mainly attributed to birth cohort rather than period effects. Spatial analysis showed high GC mortality in the Chungcheong and Gyeongsangbuk areas.

Citations

Citations to this article as recorded by  
  • Expression of claudin 18.2 in poorly cohesive carcinoma and its association with clinicopathologic parameters in East Asian patients
    Moonsik Kim, Byung Woog Kang, Jihyun Park, Jin Ho Baek, Jong Gwang Kim
    Pathology - Research and Practice.2024; 263: 155628.     CrossRef
  • Updated Epidemiology of Gastric Cancer in Asia: Decreased Incidence but Still a Big Challenge
    Wing Sum Shin, Fuda Xie, Bonan Chen, Peiyao Yu, Jun Yu, Ka Fai To, Wei Kang
    Cancers.2023; 15(9): 2639.     CrossRef
  • 5,043 View
  • 191 Download
  • 4 Web of Science
  • 2 Crossref
Close layer
General
Validation of Cancer Diagnosis Based on the National Health Insurance Service Database versus the National Cancer Registry Database in Korea
Min Soo Yang, Minae Park, Joung Hwan Back, Gyeong Hyeon Lee, Ji Hye Shin, Kyuwoong Kim, Hwa Jeong Seo, Young Ae Kim
Cancer Res Treat. 2022;54(2):352-361.   Published online August 2, 2021
DOI: https://doi.org/10.4143/crt.2021.044
AbstractAbstract PDFPubReaderePub
Purpose
This study aimed to assess the feasibility of operational definitions of cancer patients in conducting cancer-related studies using the claims data from the National Health Insurance Service (NHIS).
Materials and Methods
Cancer incidence data were obtained from the Korean Central Cancer Registry, the NHIS primary diagnosis, and from the rare and intractable disease (RID) registration program.
Results
The operational definition with higher sensitivity for cancer patient verification was different by cancer type. Using primary diagnosis, the lowest sensitivity was found in colorectal cancer (91.5%; 95% confidence interval [CI], 91.7 to 92.0) and the highest sensitivity was found in breast cancer (97.9%; 95% CI, 97.8 to 98.0). With RID, sensitivity was the lowest in liver cancer (91.9%; 95% CI, 91.7 to 92.0) and highest in breast cancer (98.1%; 95% CI, 98.0 to 98.2). In terms of the difference in the date of diagnosis in the cancer registration data, > 80% of the patients showed a < 31-day difference from the RID definition.
Conclusion
Based on the NHIS data, the operational definition of cancer incidence is more accurate when using the RID registration program claims compared to using the primary diagnosis despite the relatively lower concordance by cancer type requires additional definitions such as treatment.

Citations

Citations to this article as recorded by  
  • Smoking habit change after cancer diagnosis: effect on cardiovascular risk
    Hyeok-Hee Lee, Hokyou Lee, Deepak L Bhatt, Ga Bin Lee, Jiyen Han, Dong Wook Shin, Danbee Kang, Jong-Chan Youn, Eliseo Guallar, Juhee Cho, Hyeon Chang Kim
    European Heart Journal.2024; 45(2): 132.     CrossRef
  • Prognosis of amyotrophic lateral sclerosis patients after tracheostomy invasive ventilation in Korea
    Jong-Su Kim, Minae Park, Sojeong Park, Juhee Chae, Yoon-Ho Hong, Kyung Seok Park, Jung-Joon Sung, Seok-Jin Choi
    Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.2024; 25(3-4): 271.     CrossRef
  • Impact of coronavirus disease 2019 on cancer care: How the pandemic has changed cancer utilization and expenditures
    Jinah Sim, Jihye Shin, Hyun Jeong Lee, Yeonseung Lee, Young Ae Kim, Chong-Chi Chiu
    PLOS ONE.2024; 19(2): e0296808.     CrossRef
  • Cancer risk according to fasting blood glucose trajectories: a population-based cohort study
    Thi Minh Thu Khong, Thi Tra Bui, Hee-Yeon Kang, Jinhee Lee, Eunjung Park, Jin-Kyoung Oh
    BMJ Open Diabetes Research & Care.2024; 12(1): e003696.     CrossRef
  • Association between age-related macular degeneration and risk of incident cancer
    Junhee Park, Wonyoung Jung, Kyungdo Han, Bongseong Kim, Seung-Yeon Lee, Je Moon Yoon, Dong Hui Lim, Dong Wook Shin
    British Journal of Ophthalmology.2024; 108(9): 1249.     CrossRef
  • Association between low-dose aspirin and the risk of gastric cancer and adenoma according to a family history of gastric cancer
    Yoon Suk Jung, Mai Thi Xuan Tran, Boyoung Park, Chang Mo Moon
    Digestive and Liver Disease.2024; 56(9): 1614.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and risk of esophageal cancer in patients with diabetes mellitus: a nationwide cohort study
    Yeong Jeong Jeon, Kyungdo Han, Seung Woo Lee, Ji Eun Lee, Junhee Park, In Young Cho, Jong Ho Cho, Dong Wook Shin
    Diseases of the Esophagus.2024;[Epub]     CrossRef
  • Temporal Trend in Uptake of the National General Health Checkups and Cancer Screening Program among Korean Women with Breast Cancer
    Thi Xuan Mai Tran, Soyeoun Kim, Chihwan Cha, Boyoung Park
    Cancer Research and Treatment.2024; 56(2): 522.     CrossRef
  • Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study
    Wonyoung Jung, In Young Cho, Jinhyung Jung, Mi Hee Cho, Hye Yeon Koo, Yong-Moon Mark Park, Jong-Ha Baek, Kyungdo Han, Dong Wook Shin
    Journal of Cancer Survivorship.2024;[Epub]     CrossRef
  • Association between physical activity changes and risk of incident ischemic stroke following cancer diagnosis: A nationwide retrospective cohort study
    Wonyoung Jung, In Young Cho, Jinhyung Jung, Mi Hee Cho, Hye Yeon Koo, Yong‐Moon Mark Park, Be‐Long Cho, Hyuktae Kwon, Jin Ho Park, Kyungdo Han, Dong Wook Shin
    Cancer.2024; 130(16): 2873.     CrossRef
  • Association of decreased estimated glomerular filtration rate with lung cancer risk in the Korean population
    Soonsu Shin, Min-Ho Kim, Chang-Mo Oh, Hyejin Chun, Eunhee Ha, Hyo Choon Lee, Seong Ho Moon, Dong-Young Lee, Dosang Cho, Sangho Lee, Min Hyung Jung, Jae-Hong Ryoo
    Epidemiology and Health.2024; : e2024041.     CrossRef
  • The Trends and Outcomes of Initial Palliative Chemotherapy in Patients with Pancreatic Cancer in Korea Based on National Health Insurance Service Data
    Dong Jang, Young Kim, Jang Lee, Hakjun Kim, Yoon Lee, Jung Chun, Jong-Chan Lee, Sang Woo, Jin-Hyeok Hwang
    Journal of Clinical Medicine.2024; 13(11): 3229.     CrossRef
  • Increased risk of fragility fractures in patients with primary biliary cholangitis
    Jihye Lim, Ye-Jee Kim, Sehee Kim, Jonggi Choi
    JBMR Plus.2024;[Epub]     CrossRef
  • Increased risk of cardiovascular disease among kidney cancer survivors: a nationwide population-based cohort study
    Minji Jung, Eunjung Choo, Shufeng Li, Zhengyi Deng, Jinhui Li, Mingyi Li, Satvir Basran, Sukhyang Lee, Marvin E. Langston, Benjamin I. Chung
    Frontiers in Oncology.2024;[Epub]     CrossRef
  • Secondary Malignancies in Multiple Myeloma in Korean Patients: A Nationwide Population-Based Study
    Boyoung Park, Eunyoung Lee, Junghyun Yoon, YoungJu Park, Hyeon-Seok Eom
    Cancer Research and Treatment.2024; 56(3): 936.     CrossRef
  • Cancer Incidence Among Residents Near Coal-Fired Power Plants Based on the Korean National Health Insurance System Data
    Xue Han, Kyung-Hwa Choi, Hyungryul Lim, Jonghyuk Choi, Sanghyuk Bae, Mina Ha, Ho-Jang Kwon
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Post‐diagnosis smoking habit change and incident dementia in cancer survivors
    Hyeok‐Hee Lee, Jaeun Ahn, Changchuan Jiang, Young‐gun Lee, Hyeon Chang Kim, Hokyou Lee
    Alzheimer's & Dementia.2024;[Epub]     CrossRef
  • Increased cardiovascular disease risk among adolescents and young adults with gastric cancer
    Hea Lim Choi, Danbee Kang, Hyunsoo Kim, Juhee Cho, Keun Hye Jeon, Wonyoung Jung, Dong Wook Shin, Su-Min Jeong
    Gastric Cancer.2024; 27(6): 1169.     CrossRef
  • Trends in multiple myeloma incidence, prevalence, mortality, and survival rate in South Korea: a nationwide population-based study
    Boyoung Park, Junghyun Yoon, YooSun Lee, YoungJu Park, Hyeon-Seok Eom
    Annals of Hematology.2024; 103(10): 4111.     CrossRef
  • Real-World Outcomes of First-Line Chemotherapy in Metastatic Pancreatic Cancer: A Nationwide Population-Based Study in Korea
    Chan Su Park, Byung Kyu Park, Joung-Ho Han, Kyong Joo Lee, Kang Ju Son
    Cancers.2024; 16(18): 3173.     CrossRef
  • Chronic periodontal disease is related with newly developing hypertension: a nationwide cohort study
    Jung-Hyun Park, Min Kyoung Kang, Gwang Hyun Leem, Jin-Woo Kim, Tae-Jin Song
    Clinical Hypertension.2024;[Epub]     CrossRef
  • Smoking Habits Following Cancer Diagnosis and Heart Failure
    Hyeok-Hee Lee, Changchuan Jiang, Deepak L. Bhatt, Hyeon Chang Kim, Hokyou Lee
    JAMA Network Open.2024; 7(10): e2437867.     CrossRef
  • A Large Cohort Study of Height and Mammographic Density in Relation to Breast Cancer Risk among Korean Women
    Ga Eun Park, Sung Hun Kim, Kyungdo Han
    Cancer Epidemiology, Biomarkers & Prevention.2024; 33(11): 1484.     CrossRef
  • Breast cancer risk among women with schizophrenia and association with duration of antipsychotic use: population-based cohort study in South Korea
    Ji Su Yang, Sunghyuk Kang, Kwanghyun Kim, Alexander C. Tsai, Chul-Hyun Cho, Sun Jae Jung
    The British Journal of Psychiatry.2024; : 1.     CrossRef
  • Contrasting income-based inequalities in incidence and mortality of breast cancer in South Korea, 2006–2015
    Jinwook Bahk, Hee-Yeon Kang, Young-Ho Khang, Kyunghee Jung-Choi
    Epidemiology and Health.2024; : e2024074.     CrossRef
  • Longitudinal Trends of Comorbidities and Survival Among Kidney Cancer Patients in Asian Population
    Minji Jung, Eunjung Choo, Jinhui Li, Zhengyi Deng, Marvin E. Langston, Sukhyang Lee, Benjamin I. Chung
    Cancer Medicine.2024;[Epub]     CrossRef
  • Cancer Risk According to Alcohol Consumption Trajectories: A Population-based Cohort Study of 2.8 Million Korean Men
    Thi Tra Bui, Minji Han, Ngoc Minh Luu, Thi Phuong Thao Tran, Min Kyung Lim, Jin-Kyoung Oh
    Journal of Epidemiology.2023; 33(12): 624.     CrossRef
  • Epidemiology and comorbidities in idiopathic pulmonary fibrosis: a nationwide cohort study
    Jang Ho Lee, Hyung Jun Park, Seonok Kim, Ye-Jee Kim, Ho Cheol Kim
    BMC Pulmonary Medicine.2023;[Epub]     CrossRef
  • Fatty Liver and Risk of Head and Neck Cancer in Type 2 Diabetes Mellitus: A Nationwide Cohort Study
    Junhee Park, Kyungdo Han, Seung Woo Lee, Yeong Jeong Jeon, Sang-Man Jin, Wonyoung Jung, Yoon Kyoung So, Sang Duk Hong, Dong Wook Shin
    Cancers.2023; 15(4): 1209.     CrossRef
  • Big Data Research in the Field of Endocrine Diseases Using the Korean National Health Information Database
    Sun Wook Cho, Jung Hee Kim, Han Seok Choi, Hwa Young Ahn, Mee Kyoung Kim, Eun Jung Rhee
    Endocrinology and Metabolism.2023; 38(1): 10.     CrossRef
  • Sodium-glucose Cotransporter-2 Inhibitors and Risk of Hepatocellular Carcinoma Among Patients With Type 2 Diabetes
    Sungho Bea, Han Eol Jeong, Jae Hyeon Kim, Oriana Hy Yu, Laurent Azoulay, Ju-Young Shin
    Clinical Gastroenterology and Hepatology.2023; 21(13): 3451.     CrossRef
  • Association between Age at Helicobacter pylori Eradication and the Risk of Gastric Cancer Stratified by Family History of Gastric Cancer: A Nationwide Population-Based Study
    Yoon Suk Jung, Mai Thi Xuan Tran, Huiyeon Song, Boyoung Park, Chang Mo Moon
    Cancers.2023; 15(5): 1604.     CrossRef
  • Risk of cancer in Korean patients with psoriatic arthritis: a nationwide population-based cohort study
    Yeonghee Eun, Jiwon Hwang, Gi Hyeon Seo, Joong Kyong Ahn
    RMD Open.2023; 9(1): e002874.     CrossRef
  • Trends and Patterns of Cancer Burdens by Region and Income Level in Korea: A National Representative Big Data Analysis
    Yoon-Sun Jung, Seok-Jun Yoon
    Cancer Research and Treatment.2023; 55(2): 408.     CrossRef
  • Risk of pancreatic cancer after acute pancreatitis: A population-based matched cohort study
    Byung Kyu Park, Jeong Hun Seo, Kang Ju Son, Jung Kyu Choi
    Pancreatology.2023; 23(5): 449.     CrossRef
  • Bleeding risk and mortality according to antithrombotic agents’ exposure in cancer-related stroke patients: nationwide population-based cohort study in South Korea
    Bo Kyu Choi, Ji Sung Lee, Hae Reong Kim, Han Sang Kim, Yo Han Jung, Yu Rang Park
    BMC Neurology.2023;[Epub]     CrossRef
  • Trends in treatment patterns and survival outcomes in pancreatic cancer: A nationwide population-based study in Korea
    Byung Kyu Park, Jeong Hun Seo, Joung-Ho Han, Kyong Joo Lee, Kang Ju Son, Jung Kyu Choi
    European Journal of Cancer.2023; 189: 112932.     CrossRef
  • Mortality risk according to smoking trajectories after cancer diagnosis among Korean male cancer survivors: A population-based cohort study
    Thi Tra Bui, Minji Han, Ngoc Minh Luu, Thi Phuong Thao Tran, Sun Young Kim, Young Ae Kim, Min Kyung Lim, Jin-Kyoung Oh
    Tobacco Induced Diseases.2023; 21(May): 1.     CrossRef
  • Mutual association between family history of gastric and colorectal cancer and risk of gastric and colorectal cancer
    Yoon Suk Jung, Mai Thi Xuan Tran, Boyoung Park, Chang Mo Moon
    Journal of Gastroenterology and Hepatology.2023; 38(10): 1787.     CrossRef
  • Sex and Tumor-Site Differences in the Association of Alcohol Intake With the Risk of Early-Onset Colorectal Cancer
    Eun Hyo Jin, Kyungdo Han, Cheol Min Shin, Dong Ho Lee, Seung Joo Kang, Joo Hyun Lim, Yoon Jin Choi
    Journal of Clinical Oncology.2023; 41(22): 3816.     CrossRef
  • Differential risk of 23 site‐specific incident cancers and cancer‐related mortality among patients with metabolic dysfunction‐associated fatty liver disease: a population‐based cohort study with 9.7 million Korean subjects
    Goh Eun Chung, Su Jong Yu, Jeong‐Ju Yoo, Yuri Cho, Kyu‐na Lee, Dong Wook Shin, Yoon Jun Kim, Jung‐Hwan Yoon, Kyungdo Han, Eun Ju Cho
    Cancer Communications.2023; 43(8): 863.     CrossRef
  • Operational Definition of Liver Cancer in Studies Using Data from the National Health Insurance Service: A Systematic Review
    Yu Rim Kim, Ji Yoon Baek, Seung Hee Seo, Hyeree Park, Sooyoung Cho, Aesun Shin
    Journal of Cancer Prevention.2023; 28(2): 47.     CrossRef
  • Individual and joint effect of socioeconomic status and lifestyle factors on cancer in Korea
    Chi Lan Tran, Kui Son Choi, Sun‐Young Kim, Jin‐Kyoung Oh
    Cancer Medicine.2023; 12(16): 17389.     CrossRef
  • The impact of diabetes status on total and site-specific cancer risk in the elderly population: A nationwide cohort study
    Kyuho Kim, Bongseong Kim, Hyunho Kim, Hyung Soon Park, Yu-Bae Ahn, Seung-Hyun Ko, Kyungdo Han, Jae-Seung Yun
    Diabetes Research and Clinical Practice.2023; 203: 110866.     CrossRef
  • Changes in metabolic syndrome and the risk of breast and endometrial cancer according to menopause in Korean women
    Thi Xuan Mai Tran, Soyeoun Kim, Boyoung Park
    Epidemiology and Health.2023; 45: e2023049.     CrossRef
  • Operational Definitions of Colorectal Cancer in the Korean National Health Insurance Database
    Hyeree Park, Yu Rim Kim, Yerin Pyun, Hyundeok Joo, Aesun Shin
    Journal of Preventive Medicine and Public Health.2023; 56(4): 312.     CrossRef
  • Risk of Pancreatic Cancer and Use of Dipeptidyl Peptidase 4 Inhibitors in Patients with Type 2 Diabetes: A Propensity Score-Matching Analysis
    Mee Kyoung Kim, Kyungdo Han, Hyuk-Sang Kwon, Soon Jib Yoo
    Endocrinology and Metabolism.2023; 38(4): 426.     CrossRef
  • Changes in physical activity and incident cardiovascular events in cancer survivors
    Hyeok-Hee Lee, Hokyou Lee, Deepak L Bhatt, Danbee Kang, Jong-Chan Youn, Dong Wook Shin, Juhee Cho, Hyeon Chang Kim
    European Heart Journal.2023; 44(47): 4997.     CrossRef
  • Mammographic Breast Density and Risk of Ovarian Cancer in Korean Women
    Thi Xuan Mai Tran, Soyeoun Kim, Boyoung Park
    Cancer Epidemiology, Biomarkers & Prevention.2023; 32(12): 1690.     CrossRef
  • Risk factors for early-onset lung cancer in Korea: analysis of a nationally representative population-based cohort
    Jihun Kang, Taeyun Kim, Kyung-Do Han, Jin-Hyung Jung, Su-Min Jeong, Yo Hwan Yeo, Kyuwon Jung, Hyun Lee, Jong Ho Cho, Dong Wook Shin
    Epidemiology and Health.2023; 45: e2023101.     CrossRef
  • Increased risk of cancer and cancer-related mortality in middle-aged Korean women with prediabetes and diabetes: a population-based study
    Thi Xuan Mai Tran, Soyeoun Kim, Huiyeon Song, Boyoung Park
    Epidemiology and Health.2023; 45: e2023080.     CrossRef
  • Temporal patterns of chronic disease incidence after breast cancer: a nationwide population-based cohort study
    Danbee Kang, Minwoong Kang, Yun Soo Hong, Jihwan Park, Jin Lee, Hwa Jeong Seo, Dong Wook Kim, Jin Seok Ahn, Yeon Hee Park, Se Kyung Lee, Dong Wook Shin, Eliseo Guallar, Juhee Cho
    Scientific Reports.2022;[Epub]     CrossRef
  • Association Between Family History of Gastric Cancer and the Risk of Gastric Cancer and Adenoma: A Nationwide Population-Based Study
    Yoon Suk Jung, Mai Thi Xuan Tran, Boyoung Park, Chang Mo Moon
    American Journal of Gastroenterology.2022; 117(8): 1255.     CrossRef
  • Longitudinal Changes in Smoking Habits in Women and Subsequent Risk of Cancer
    Thi Xuan Mai Tran, Soyeoun Kim, Huiyeon Song, Boyoung Park
    American Journal of Preventive Medicine.2022; 63(6): 894.     CrossRef
  • Incidence, mortality, and survival of liver cancer using Korea central cancer registry database: 1999-2019
    Sung Yeon Hong, Mee Joo Kang, Taegyu Kim, Kyu-Won Jung, Bong-Wan Kim
    Annals of Hepato-Biliary-Pancreatic Surgery.2022; 26(3): 211.     CrossRef
  • Difference in medical service use among Korean gastric cancer survivors according to regional healthcare vulnerabilities: a cohort study
    Sung Hoon Jeong, Jae Hong Joo, Minah Park, Choa Yun, Soo Hyun Kang, Eun-Cheol Park, Yoon Dae Han, Sung-In Jang
    Supportive Care in Cancer.2022; 30(11): 9233.     CrossRef
  • Cancer risk associated with the use of valsartan in Korea: A nationwide cohort study
    Ha-Lim Jeon, Seon Hee Lee, Jin Hyun Nam, Ju-Young Shin
    Cancer Epidemiology.2022; 80: 102245.     CrossRef
  • Association between A Family History of Colorectal Cancer and the Risk of Colorectal Cancer: A Nationwide Population-Based Study
    Yoon Suk Jung, Huiyeon Song, Mai Thi Xuan Tran, Boyoung Park, Chang Mo Moon
    Journal of Personalized Medicine.2022; 12(10): 1566.     CrossRef
  • The Association Between Metabolic Syndrome and Colorectal Cancer Risk by Obesity Status in Korean Women: A Nationwide Cohort Study
    Seong-geun Moon, Boyoung Park
    Journal of Preventive Medicine and Public Health.2022; 55(5): 475.     CrossRef
  • Microcalcifications, mammographic breast density, and risk of breast cancer: a cohort study
    Soyeoun Kim, Thi Xuan Mai Tran, Huiyeon Song, Boyoung Park
    Breast Cancer Research.2022;[Epub]     CrossRef
  • Association between malignancy risk and Janus kinase inhibitors versus tumour necrosis factor inhibitors in Korean patients with rheumatoid arthritis: a nationwide population-based study
    Yeo-Jin Song, Soo-Kyung Cho, Seung-Hun You, Jeong-Yeon Kim, Hyoungyoung Kim, Sun-Young Jung, Yoon-Kyoung Sung
    RMD Open.2022; 8(2): e002614.     CrossRef
  • Association Between Metabolic Syndrome and Risk of Esophageal Cancer: a Nationwide Population-Based Study
    Ji Eun Lee, Kyungdo Han, Juhwan Yoo, Yohwan Yeo, In Young Cho, Belong Cho, Jin-Ho Park, Dong Wook Shin, Jong Ho Cho, Yong-Moon Park
    Cancer Epidemiology, Biomarkers & Prevention.2022; 31(12): 2228.     CrossRef
  • Risk of non-Hodgkin lymphoma in breast cancer survivors: a nationwide cohort study
    Danbee Kang, Sang Eun Yoon, Dongwook Shin, Jin Lee, Yun Soo Hong, Se Kyung Lee, Jeong Eon Lee, Yeon Hee Park, Jin Seok Ahn, Eliseo Guallar, Won Seog Kim, Jungho Lee, Seok Jin Kim, Juhee Cho
    Blood Cancer Journal.2021;[Epub]     CrossRef
  • 9,371 View
  • 373 Download
  • 63 Web of Science
  • 63 Crossref
Close layer
Gastrointestinal Cancer
Fasting Blood Glucose, Cholesterol, and Risk of Primary Liver Cancer: The Kailuan Study
Xiangming Ma, Haozhe Cui, Miaomiao Sun, Qian Liu, Xining Liu, Guangjian Li, Yaochen Wei, Qingjiang Fu, Siqing Liu, Liying Cao
Cancer Res Treat. 2021;53(4):1113-1122.   Published online January 19, 2021
DOI: https://doi.org/10.4143/crt.2020.817
AbstractAbstract PDFPubReaderePub
Purpose
The influence of fasting blood glucose (FBG) and cholesterolemia primary liver cancer (PLC) in china was analyzed via a large prospective cohort study based on a community population, and the combined effects between them were investigated.
Materials and Methods
Overall, 98,936 staff from the Kailuan Group who participated in and finished physical examinations between 2006 and 2007 were included in the cohort study. Their medical information was collected and they were followed up after examination. The correlations of serum FBG or TC with PLC were analyzed. Then, we categorized all staff into four groups: normal FBG/ non-hypocholesterolemia, normal FBG/hypocholesterolemia, elevated FBG/non-hypocholesterolemia, elevated FBG/hypocholesterolemia and normal FBG/ non-hypocholesterolemia was used as a control group. The combined effects of elevated FBG and hypocholesterolemia with PLC were analyzed using the Age-scale Cox proportional hazard regression model.
Results
During 1,134,843.68 person*years follow up, a total of 388 PLC cases occured. We found the elevated FBG and hypocholesterolemia increases the risk for PLC, respectively. Compared with the non-hypocholesterolemia/normal FBG group, the risk of PLC was significantly increased in the non-hypocholesterolemia/elevated FBG group (HR=1.19,95%CI 0.88–1.62) and hypocholesterolemia/normal FBG group (HR=1.53,95%CI 1.19–1.97), and in the hypocholesterolemia/elevated FBG group (HR=3.16 95%CI2.13-4.69). And, a significant interaction effect was found of FBG and TC on PLC. All results were independent from the influence of liver disease.
Conclusion
Elevated serum FBG and hypocholesterolemia are risk factors for PLC, especially when combined. Thus, for the prevention and treatment of PLC, serum FBG and TC levels should be investigated.

Citations

Citations to this article as recorded by  
  • Association between Metabolically Healthy Status and Risk of Gastrointestinal Cancer
    Haozhe Cui, Fei Tian, Yongliang Chen, Xiangming Ma
    Cancer Research and Treatment.2024; 56(1): 238.     CrossRef
  • Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model
    Emily M. Hawes, Derek P. Claxton, James K. Oeser, Richard M. O’Brien
    Bioscience Reports.2024;[Epub]     CrossRef
  • Primary hypocholesterolemia is associated with an increased risk of hepatic complications in the general population
    Matthieu Wargny, Thomas Goronflot, Antoine Rimbert, Jérôme Boursier, Sofiane Kab, Joseph Henny, Antoine Lainé, Christophe Leux, Sarra Smati, Samy Hadjadj, Cédric Le May, Marcel Goldberg, Marie Zins, Bertrand Cariou
    Journal of Hepatology.2024; 80(6): 846.     CrossRef
  • Biochemical and metabolic characterization of a G6PC2 inhibitor
    Emily M. Hawes, Mohsin Rahim, Zeinab Haratipour, Abigail R. Orun, Margaret L. O'Rourke, James K. Oeser, Kwangho Kim, Derek P. Claxton, Ray D. Blind, Jamey D. Young, Richard M. O'Brien
    Biochimie.2024; 222: 109.     CrossRef
  • Nanomaterials modulate tumor-associated macrophages for the treatment of digestive system tumors
    Hao Li, Shuai Wang, Zhengqiang Yang, Xianwei Meng, Meng Niu
    Bioactive Materials.2024; 36: 376.     CrossRef
  • Association between transitions in metabolic health and colorectal cancer across categories of body size phenotype: a prospective cohort study
    Qian Liu, Fei Si, Yuntao Wu, Jing Yu
    Obesity.2024; 32(10): 1948.     CrossRef
  • The role of glucose-6-phosphatase activity in glucose homeostasis and its potential for diabetes therapy
    Lay Shuen Tan, Hwee Hui Lau, Essam M. Abdelalim, Chin Meng Khoo, Richard M. O’Brien, E. Shyong Tai, Adrian Kee Keong Teo
    Trends in Molecular Medicine.2024;[Epub]     CrossRef
  • Abdominal obesity, chronic inflammation and the risk of non-alcoholic fatty liver disease
    Dongna Zhao, Haozhe Cui, Zhiqiang Shao, Liying Cao
    Annals of Hepatology.2023; 28(4): 100726.     CrossRef
  • Fasting plasma glucose and alanine aminotransferase on the risk of hepatocellular carcinoma: A nested case-control study
    Lizhen Zhang, Zhongge Wang, Ruirui Chen, Zhiyuan Cheng, Jingli Yang, Jing Li, Siyu Li, Yarong Chen, Lulu Xu, Yujia Hu, Yana Bai
    Cancer Epidemiology.2023; 84: 102362.     CrossRef
  • Lipids, cholesterols, statins and liver cancer: a Mendelian randomization study
    Zicheng Liang, Zhen Zhang, Xiaoning Tan, Puhua Zeng
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • Triglyceride-glucose index associated with the risk of cardiovascular disease: the Kailuan study
    Qian Liu, Haozhe Cui, Yihan Ma, Xu Han, Zhiwei Cao, Yuntao Wu
    Endocrine.2022; 75(2): 392.     CrossRef
  • Cumulative triglyceride-glucose index is a risk for CVD: a prospective cohort study
    Haozhe Cui, Qian Liu, Yuntao Wu, Liying Cao
    Cardiovascular Diabetology.2022;[Epub]     CrossRef
  • Association of triglyceride–glucose index and traditional risk factors with cardiovascular disease among non-diabetic population: a 10-year prospective cohort study
    Li Liu, Zhenguo Wu, Yifan Zhuang, Yerui Zhang, Huiliang Cui, Fanghong Lu, Jie Peng, Jianmin Yang
    Cardiovascular Diabetology.2022;[Epub]     CrossRef
  • 6,474 View
  • 118 Download
  • 13 Web of Science
  • 13 Crossref
Close layer
Gastrointestinal cancer
Television Viewing Time and the Risk of Colorectal Cancer Mortality among Japanese Population: The JACC Study
Yuting Li, Ehab S. Eshak, Renzhe Cui, Kokoro Shirai, Keyang Liu, Hiroyasu Iso, Satoyo Ikehara, Akiko Tamakoshi, Shigekazu Ukawa, JACC Study Group
Cancer Res Treat. 2021;53(2):497-505.   Published online October 27, 2020
DOI: https://doi.org/10.4143/crt.2020.327
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
Sedentary behavior attributes to the increased risk of some cancers and all-cause mortality. The evidence is limited for the association between television (TV) viewing time, a major sedentary behavior, and risk of colorectal cancer death. We aimed to examine this association in Japanese population.
Materials and Methods
A prospective cohort study encompassed of 90,834 men and women aged 40-79 years with no prior history of colorectal cancer who completed a self-administered food frequency questionnaire, and provided their TV viewing information. The participants were followed-up from 1988-1990 to the end of 2009. The hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated by the Cox proportional hazard regression for risk of colorectal cancer mortality according to TV viewing time.
Results
During the median 19.1-year follow-up period, we documented 749 (385 men and 364 women) colorectal cancer deaths. The multivariable-adjusted HRs for mortality from colorectal cancer were 1.11 (0.88-1.41) for 1.5 to < 3 hr/day, 1.14 (0.91-1.42) for 3 to < 4.5 hr/day and 1.33 (1.02-1.73) for ≥ 4.5 hr/day in comparison to < 1.5 hr/day TV watching; p-trend=0.038, and that for 1-hour increment in TV viewing time was 1.06 (1.01-1.11). Moreover, the multivariable-adjusted HR (95%CI) of colon cancer for 1-hour increment in TV viewing time was 1.07 (1.02-1.13). Age, body mass index, and level of leisure-physical activity did not show significant effect modifications on the observed associations.
Conclusion
TV viewing time is associated with the increased risk of colorectal cancer mortality among Japanese population, more specifically colon rather than rectal cancer.

Citations

Citations to this article as recorded by  
  • The causal effects of leisure screen time on irritable bowel syndrome risk from a Mendelian randomization study
    Liesheng Lu, Changqin Liu, Kunpeng Liu, Chenzhang Shi, Zhongchen Liu, Xun Jiang, Feng Wang
    Scientific Reports.2023;[Epub]     CrossRef
  • Association of Physical Activity and Sedentary Behavior With the Risk of Colorectal Cancer
    Sanghyun An, Sungjin Park
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
  • Sedentary behavior and cancer–an umbrella review and meta-analysis
    Rafael Hermelink, Michael F. Leitzmann, Georgios Markozannes, Kostas Tsilidis, Tobias Pukrop, Felix Berger, Hansjörg Baurecht, Carmen Jochem
    European Journal of Epidemiology.2022; 37(5): 447.     CrossRef
  • 7,410 View
  • 137 Download
  • 4 Web of Science
  • 3 Crossref
Close layer
Gynecologic cancer
Nationwide Comparison of Surgical and Oncologic Outcomes in Endometrial Cancer Patients Undergoing Robotic, Laparoscopic, and Open Surgery: A Population-Based Cohort Study
Kyung-Jin Eoh, Eun-Ji Nam, Sang-Wun Kim, Minkyung Shin, Stella J-H Kim, Jung-Ae Kim, Yong-Tae Kim
Cancer Res Treat. 2021;53(2):549-557.   Published online October 22, 2020
DOI: https://doi.org/10.4143/crt.2020.802
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
Population-based comparisons between minimally invasive surgery (MIS) (robotic surgery [RS] and laparoscopic surgery [LS]) and open surgery (OS) for managing endometrial cancer are lacking. This study aimed to compare surgical and oncologic outcomes between endometrial cancer patients who underwent surgical staging via MIS or OS.
Materials and Methods
A population-based retrospective cohort study was performed using claims data from the Korean National Health Insurance database from January 2012 to December 2016. All patients who underwent hysterectomy under diagnosis of endometrial cancer were identified. Patients were classified into RS, LS, and OS groups. Operative and oncologic outcomes were compared among the three groups after adjustments for age group, risk group (adjuvant therapy status), modified Charlson comorbidity index, income level, insurance type, and index year using propensity scores obtained via the inverse probability of treatment weighted method.
Results
After adjustment, 5,065 patients (RS, n=315; LS, n=3,248; OS, n=1,503) were analyzed. Patient demographics were comparable. Hospital stay, postoperative complications, and cost were more favorable in the RS and LS groups than in the OS group (all p < 0.001). Five-year overall survival was significantly longer in the RS and LS groups than in the OS group (94.8%, 91.9%, and 86.9%, respectively; p < 0.001). Moreover, the survival benefit of RS was shown in the subgroup analysis of low-risk endometrial cancer patients.
Conclusion
Our study provides further evidence for the RS being a safe surgical alternative to the LS and OS, especially in low-risk endometrial cancer patients, offering surgical and oncologic outcomes equivalent to other surgical approaches.

Citations

Citations to this article as recorded by  
  • Robot-assisted pelvic and renal surgery compared with laparoscopic or open surgery: Literature review of cost-effectiveness and clinical outcomes
    Thomas Davidson, Rune Sjödahl, Åke Aldman, Claes Lennmarken, Ann-Sofi Kammerlind, Elvar Theodorsson
    Scandinavian Journal of Surgery.2024; 113(1): 13.     CrossRef
  • Progress of Research on the Application of Robotic Surgical System in Gynecologic Malignancies
    璐 余
    Advances in Clinical Medicine.2024; 14(03): 327.     CrossRef
  • Sociodemographic, clinical characteristics, and treatment patterns of endometrial cancer cases in Puerto Rico during the period 2009 to 2015: A retrospective study
    Yisel Pagán Santana, Maira Castañeda Ávila, Ruth Ríos Motta, Karen J. Ortiz Ortiz, Asmerom Tesfamariam Sengal
    PLOS ONE.2024; 19(5): e0302253.     CrossRef
  • Comparison of Long-Term Outcomes in Early-Stage Endometrial Cancer: Robotic Single-Site vs. Multiport Laparoscopic Surgery
    Heeju Kang, Hyewon Chung, Seungmee Lee, Tae-Kyu Jang, So-Jin Shin, Sang-Hoon Kwon, Chi-Heum Cho
    Journal of Personalized Medicine.2024; 14(6): 601.     CrossRef
  • Impact of Robotic Assistance on Minimally Invasive Surgery for Type II Endometrial Cancer: A National Cancer Database Analysis
    Kelly Lamiman, Michael Silver, Nicole Goncalves, Michael Kim, Ioannis Alagkiozidis
    Cancers.2024; 16(14): 2584.     CrossRef
  • Clinical Relevance of Uterine Manipulation on Oncologic Outcome in Robot-Assisted versus Open Surgery in the Management of Endometrial Cancer
    Kyung Jin Eoh, Yoo-Na Kim, Eun Ji Nam, Sang Wun Kim, Young Tae Kim
    Journal of Clinical Medicine.2023; 12(5): 1950.     CrossRef
  • Trend and characteristics of minimally invasive surgery for patients with endometrial cancer in Japan
    Hiroshi Yoshida, Hiroko Machida, Koji Matsuo, Yoshito Terai, Takuma Fujii, Masaki Mandai, Kei Kawana, Hiroaki Kobayashi, Mikio Mikami, Satoru Nagase
    Journal of Gynecologic Oncology.2023;[Epub]     CrossRef
  • Clinical Relevance of Red Blood Cell Distribution Width (RDW) in Endometrial Cancer: A Retrospective Single-Center Experience from Korea
    Kyung-Jin Eoh, Tae-Kyung Lee, Eun-Ji Nam, Sang-Wun Kim, Young-Tae Kim
    Cancers.2023; 15(15): 3984.     CrossRef
  • Robot-Assisted Surgery in the Treatment of Gynecological Carcinoma and Malignancies: Introduction to the da Vinci Robotic Surgery System
    Arnav Goel, Soumya Pamnani, Ashish Anjankar
    Cureus.2023;[Epub]     CrossRef
  • Robot-assisted versus conventional laparoscopic surgery for endometrial cancer: long-term comparison of outcomes
    Kyung Jin Eoh, Tae-Joong Kim, Jeong-Yeol Park, Hee Seung Kim, Jiheum Paek, Young Tae Kim
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • Comparison of Single-Port Laparoscopy with Other Surgical Approaches in Endometrial Cancer Surgical Staging: Propensity-Score-Matched Analysis
    Sang Hyun Cho, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Young Tae Kim, Sang Wun Kim
    Cancers.2023; 15(22): 5322.     CrossRef
  • Short-Term Outcome of Robotic versus Laparoscopic Hysterectomy for Endometrial Cancer in Women with Diabetes: Analysis of the US Nationwide Inpatient Sample
    Huang-Pin Shen, Chih-Jen Tseng
    Journal of Clinical Medicine.2023; 12(24): 7713.     CrossRef
  • Laparoscopic vs. open procedure for intermediate‑ and high‑risk endometrial cancer: a minimum 4-year follow-up analysis
    Xing Zhou, Sitian Wei, Qingchun Shao, Jun Zhang, Rong Zhao, Rui Shi, Wei Zhang, Kejun Dong, Wan Shu, Hongbo Wang
    BMC Cancer.2022;[Epub]     CrossRef
  • Oncologic safety of laparoscopic surgery for women with apparent early‐stage uterine serous carcinoma: A multi‐institutional retrospective cohort study
    Yu Xu, Juan Shen, Qianwen Zhang, Yuedong He, Cheng Chen, Yong Tian
    International Journal of Gynecology & Obstetrics.2022; 158(1): 162.     CrossRef
  • Impact of lymphadenectomy on short- and long-term complications in patients with endometrial cancer
    Louisa Proppe, Ibrahim Alkatout, Ricarda Koch, Sascha Baum, Christos Kotanidis, Achim Rody, Lars C. Hanker, Georgios Gitas
    Archives of Gynecology and Obstetrics.2022; 306(3): 811.     CrossRef
  • Survival Analysis in Endometrial Carcinomas by Type of Surgical Approach: A Matched-Pair Study
    Pluvio J. Coronado, Agnieszka Rychlik, Laura Baquedano, Virginia García-Pineda, Maria A. Martínez-Maestre, Denis Querleu, Ignacio Zapardiel
    Cancers.2022; 14(4): 1081.     CrossRef
  • Robot-assisted versus laparoscopic minimally invasive surgery for the treatment of stage I endometrial cancer
    Peter A. Argenta, Jordan Mattson, Colleen L. Rivard, Elizabeth Luther, Alexandra Schefter, Rachel I. Vogel
    Gynecologic Oncology.2022; 165(2): 347.     CrossRef
  • Effects of Quantitative Nursing Combined with Psychological Intervention in Operating Room on Stress Response, Psychological State, and Prognosis of Patients Undergoing Laparoscopic Endometrial Cancer Surgery
    Xiaojing Chen, Huiyan Li, Shouyan Wang, Yu Wang, Li Zhang, Dandan Yao, Li Li, Ge Gao, Shakeel Ahmad
    Computational and Mathematical Methods in Medicine.2022; 2022: 1.     CrossRef
  • Increased HSF1 Promotes Infiltration and Metastasis in Cervical Cancer via Enhancing MTDH-VEGF-C Expression
    Xueyan Shi, Zhenghao Deng, Shouman Wang, Shuai Zhao, Lan Xiao, Jiang Zou, Tao Li, Sichuang Tan, SipAin Tan, Xianzhong Xiao
    OncoTargets and Therapy.2021; Volume 14: 1305.     CrossRef
  • Surgical and Patient Outcomes of Robotic Versus Conventional Laparoscopic Hysterectomy: A Systematic Review
    Khadija Alshowaikh, Katarzyna Karpinska-Leydier, Jashvini Amirthalingam , Gokul Paidi, Anuruddhika I Iroshani Jayarathna, Divya Bala Anthony Manisha R Salibindla, Huseyin Ekin Ergin
    Cureus.2021;[Epub]     CrossRef
  • Surgical outcomes of robotic-assisted surgery in endometrial cancer:comparison with laparoscopic surgery and laparotomy
    Yoshitsugu Chigusa, Sae Yu, Naoki Horikawa, Haruko Okamoto, Masumi Sunada, Ukita Masayo, Koji Yamanoi, Ken Yamaguchi, Akihito Horie, Masaki Mandai
    JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY.2021; 37(2): 10.     CrossRef
  • 7,265 View
  • 218 Download
  • 20 Web of Science
  • 21 Crossref
Close layer
Time Trends for Prostate Cancer Incidence from 2003 to 2013 in South Korea: An Age-Period-Cohort Analysis
Hyun Young Lee, Do Kyoung Kim, Seung Whan Doo, Won Jae Yang, Yun Seob Song, Bora Lee, Jae Heon Kim
Cancer Res Treat. 2020;52(1):301-308.   Published online August 1, 2019
DOI: https://doi.org/10.4143/crt.2019.194
AbstractAbstract PDFPubReaderePub
Purpose
Prostate cancer (PCa) incidence is affected by aging phenomenon and performance of screening test. In United States, PCa incidence is affected by period effect of U.S. Preventive Services Task Force (USPSTF) recommendation. However, no study has reported the effect of USPSTF recommendation or aging phenomenon on PCa incidence in South Korea. Thus, the objective of this study was to investigate effects of age, period, and birth cohort on PCa incidence using age-period-cohort analysis.
Materials and Methods
Annual report of cancer statistics between 2003 and 2013 from National Health Insurance Service (NHIS) in South Korea for the number of PCa patients and Korean Statistical Information Service (KOSIS) data between 2003 and 2013 from national statistics in South Korea for the number of Korean male population were used. Age-period-cohort models were used to investigate effects of age, period, and birth cohort on PCa incidence.
Results
Overall PCa incidence in South Korea was increased 8.8% in annual percentage (95% confidential interval, 6.5 to 11.2; p < 0.001). It showed an increasing pattern from 2003 to 2011 but a decreasing pattern from 2011 to 2013. Age increased the risk of PCa incidence. However, the speed of increase was slower with increasing age. PCa incidence was increased 1.4 times in 2008 compared to that in 2003 or 2013. Regarding cohort effect, the risk of PCa incidence started to increase from 1958 cohort.
Conclusion
PCa incidence was affected by period of specific year. There was a positive cohort effect on PCa incidence associated with age structural change.

Citations

Citations to this article as recorded by  
  • Incidence trends and spatial distribution of thyroid cancer in the Chinese female population from 1990 to 2019
    Xiaowei Qiao, Yunshang Cui, Changgeng Ma, Chunxiao Ma, Bingyu Bai, Chunping Wang
    Asia-Pacific Journal of Oncology Nursing.2024; 11(7): 100529.     CrossRef
  • Exploring Prostate Cancer Incidence Trends and Age Change in Cancer Registration Areas of Jiangsu Province, China, 2009 to 2019
    Hairong Zhou, Xin Hong, Weigang Miao, Weiwei Wang, Chenchen Wang, Renqiang Han, Jinyi Zhou
    Current Oncology.2024; 31(9): 5516.     CrossRef
  • A Web-Based Decision Aid for Informed Prostate Cancer Screening: Development and Pilot Evaluation
    Wonyoung Jung, In Young Cho, Keun Hye Jeon, Yohwan Yeo, Jae Kwan Jun, Mina Suh, Ansuk Jeong, Jungkwon Lee, Dong Wook Shin
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Regional disparities in major cancer incidence in Korea, 1999-2018
    Eun Hye Park, Mee Joo Kang, Kyu-Won Jung, Eun Hye Park, E Hwa Yun, Hye-Jin Kim, Hyun-Joo Kong, Chang Kyun Choi, Jeong-Soo Im, Hong Gwan Seo
    Epidemiology and Health.2023; 45: e2023089.     CrossRef
  • Time Trends in Psoriasis and Psoriatic Arthritis Incidence from 2002 to 2016 in Taiwan: An Age–Period–Cohort Analysis
    Yu-Tsung Chen, Chih-Yi Wu, Yu-Ling Li, Li-Ying Chen, Hung-Yi Chiou
    Journal of Clinical Medicine.2022; 11(13): 3744.     CrossRef
  • The burden of endometriosis in China from 1990 to 2019
    Yan Wang, Xiaoyan Wang, Kaijun Liao, Baoqin Luo, Jiashou Luo
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Impact of Benign Prostatic Hyperplasia and/or Prostatitis on the Risk of Prostate Cancer in Korean Patients
    Sung Han Kim, Whi-An Kwon, Jae Young Joung
    The World Journal of Men's Health.2021; 39(2): 358.     CrossRef
  • Can Prostate-Specific Antigen Density Be an Index to Distinguish Patients Who Can Omit Repeat Prostate Biopsy in Patients with Negative Magnetic Resonance Imaging?
    Jiwoong Yu, Youngjun Boo, Minyong Kang, Hyun Hwan Sung, Byong Chang Jeong, Seongil Seo, Seong soo Jeon, Hyunmoo Lee, Hwang Gyun Jeon
    Cancer Management and Research.2021; Volume 13: 5467.     CrossRef
  • Long-term trends in the incidence of endometriosis in China from 1990 to 2019: a joinpoint and age–period–cohort analysis
    Jinhui Feng, Shitong Zhang, Jiadong Chen, Jie Yang, Jue Zhu
    Gynecological Endocrinology.2021; 37(11): 1041.     CrossRef
  • Personalized 5-Year Prostate Cancer Risk Prediction Model in Korea Based on Nationwide Representative Data
    Yohwan Yeo, Dong Wook Shin, Jungkwon Lee, Kyungdo Han, Sang Hyun Park, Keun Hye Jeon, Jungeun Shin, Aesun Shin, Jinsung Park
    Journal of Personalized Medicine.2021; 12(1): 2.     CrossRef
  • Association between SOD2 V16A variant and urological cancer risk
    Li-Feng Zhang, Kai Xu, Bo-Wen Tang, Wei Zhang, Wei Yuan, Chuang Yue, Li Shi, Yuan-Yuan Mi, Li Zuo, Li-Jie Zhu
    Aging.2020; 12(1): 825.     CrossRef
  • 7,029 View
  • 246 Download
  • 12 Web of Science
  • 11 Crossref
Close layer
The Effect of Disability on the Diagnosis and Treatment of Multiple Myeloma in Korea: A National Cohort Study
Jihyun Kwon, So Young Kim, Kyoung Eun Yeob, Hye Sook Han, Ki Hyeong Lee, Dong Wook Shin, Yeon-Yong Kim, Jong Heon Park, Jong Hyock Park
Cancer Res Treat. 2020;52(1):1-9.   Published online April 22, 2019
DOI: https://doi.org/10.4143/crt.2018.702
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
This study aimed to determine whether the diagnosis, treatment approach, and prognosis of multiple myeloma (MM) vary according to the presence and type of disability.
Materials and Methods
Demographic, socioeconomic, and medical data were obtained from the National Disability Database, the Korean Central Cancer Registry, and the Korean National Health Insurance claims database. An age- and sex-matched cohort was established using a 1:3 ratio constituted with 2,776,450 people with disabilities and 8,329,350 people without disabilities. Adult patients diagnosed with MM were subsequently selected from this cohort. Disabilities were categorized as physical, communication, intellectual or psychological, and affecting the major internal organs.
Results
The cohort included 4,090 patients with MM, with a significantly lower rate per 100,000 persons among people with disabilities than among people without disabilities (29.1 vs. 39.4, p < 0.001). People with disabilities were more likely to undergo dialysis treatment at the time of diagnosis (16.3% vs. 10.0%, p < 0.001), but were less likely to undergo autologous stem cell transplantation (37.5% vs. 43.7%, p=0.072). This trend was more evident among patients with intellectual or psychological disabilities. The median overall survival among patients with disabilities was significantly shorter than that among patients without disabilities (36.8 months vs. 51.2 months, p < 0.001).
Conclusion
In Korea, people with disabilities generally have a lower rate of MM diagnosis, receive less intensive treatment, and have a lower survival rate than people without disabilities.

Citations

Citations to this article as recorded by  
  • Case report: IORT as an alternative treatment option for breast cancer patients with difficulty staying still
    Fardeen Bhimani, Maureen McEvoy, Yu Chen, Anjuli Gupta, Jessica Pastoriza, Shani Fruchter, Zachary C. Bitan, Wolfgang A. Tomé, Keyur Mehta, Jana Fox, Sheldon Feldman
    Frontiers in Oncology.2024;[Epub]     CrossRef
  • The Korea National Disability Registration System
    Miso Kim, Wonyoung Jung, So Young Kim, Jong Hyock Park, Dong Wook Shin
    Epidemiology and Health.2023; 45: e2023053.     CrossRef
  • Do people with disabilities experience disparities in cancer care? A systematic review
    Irene Tosetti, Hannah Kuper, Sina Azadnajafabad
    PLOS ONE.2023; 18(12): e0285146.     CrossRef
  • Cancer detection, diagnosis, and treatment for adults with disabilities
    Lisa I Iezzoni
    The Lancet Oncology.2022; 23(4): e164.     CrossRef
  • Disparities in All-Cause Mortality in Older Patients with Colorectal Cancer According to Disability Status: A Nationwide Analysis
    Woo-Ri Lee, Kyu-Tae Han, Mingee Choi, Woorim Kim
    Current Oncology.2022; 29(10): 7430.     CrossRef
  • Disparities in prostate cancer diagnosis, treatment, and survival among men with disabilities: Retrospective cohort study in South Korea
    Dong Wook Shin, Jinsung Park, Kyoung Eun Yeob, Seok Jung Yoon, Soong-nang Jang, So Young Kim, Jong Heon Park, Jong Hyock Park, Ichiro Kawachi
    Disability and Health Journal.2021; 14(4): 101125.     CrossRef
  • Disparities in the Diagnosis, Treatment, and Survival Rate of Cervical Cancer among Women with and without Disabilities
    Jin Young Choi, Kyoung Eun Yeob, Seung Hwa Hong, So Young Kim, Eun-Hwan Jeong, Dong Wook Shin, Jong Heon Park, Gil-won Kang, Hak Soon Kim, Jong Hyock Park, Ichiro Kawachi
    Cancer Control.2021;[Epub]     CrossRef
  • Disparities in the Diagnosis and Treatment of Gastric Cancer in Relation to Disabilities
    Hyoung Woo Kim, Dong Wook Shin, Kyoung Eun Yeob, In Young Cho, So Young Kim, Seon Mee Park, Jong Heon Park, Jong Hyock Park, Ichiro Kawachi
    Clinical and Translational Gastroenterology.2020; 11(10): e00242.     CrossRef
  • 9,418 View
  • 365 Download
  • 7 Web of Science
  • 8 Crossref
Close layer
Television Viewing Time and Breast Cancer Incidence for Japanese Premenopausal and Postmenopausal Women: The JACC Study
Jinhong Cao, Ehab Salah Eshak, Keyang Liu, Isao Muraki, Renzhe Cui, Hiroyasu Iso, Akiko Tamakoshi, JACC Study Group
Cancer Res Treat. 2019;51(4):1509-1517.   Published online March 21, 2019
DOI: https://doi.org/10.4143/crt.2018.705
AbstractAbstract PDFPubReaderePub
Purpose
The evidence on effects of TV viewing time among premenopausal and postmenopausal women for breast cancer risk remains controversial and limited.
Materials and Methods
A prospective study encompassing 33,276 (17,568 premenopausal, and 15,708 postmenopausal) women aged 40-79 years in whom TV viewing time, menstrual, and reproductive histories were determined by a self-administered questionnaire. The follow-up was from 1988 to 2009 and hazard ratios (HRs) with 95% confidence intervals (CIs) of breast cancer incidence were calculated for longer TV viewing time in reference to shorter TV viewing time by Cox proportional hazard models.
Results
During 16.8-year median follow-up, we found positive associations between TV viewing time and breast cancer incidence with a borderline significant trend among total women and a significant trend among postmenopausal women. Among total women, the multivariable HRs (95% CIs) for risk of breast cancer in reference to < 1.5 hr/day of TV viewing time were 0.89 (0.59-1.34) for 1.5 to < 3.0 hr/day, 1.19 (0.82-1.74) for 3.0 to < 4.5 hr/day, and 1.45 (0.91-2.32) for ≥ 4.5 hr/day (p for trend=0.053) and among postmenopausal women, the corresponding risk estimates were 1.10 (0.42-2.88), 2.54 (1.11-5.80), and 2.37 (0.92-6.10) (p for trend=0.009), respectively.
Conclusion
Prolonged TV viewing time was associated with increased risk of breast cancer, especially among postmenopausal women.

Citations

Citations to this article as recorded by  
  • METTL3 regulates FAM83D m6A modification to accelerate tumorigenesis of triple-negative breast cancer via the Wnt/β-catenin pathway
    Xiaodong Yu, Yaxun Li, Fanshuang Kong, Qun Xu
    Toxicology in Vitro.2024; 95: 105746.     CrossRef
  • Risk Factors for Female Breast Cancer: A Population Cohort Study
    Yu-Chiao Wang, Ching-Hung Lin, Shih-Pei Huang, Mingchih Chen, Tian-Shyug Lee
    Cancers.2022; 14(3): 788.     CrossRef
  • Sedentary behavior and risk of breast cancer: a dose–response meta-analysis from prospective studies
    Feifei Chong, Yanli Wang, Mengmeng Song, Qiuyu Sun, Weihong Xie, Chunhua Song
    Breast Cancer.2021; 28(1): 48.     CrossRef
  • Television Viewing Time and the Risk of Colorectal Cancer Mortality among Japanese Population: The JACC Study
    Yuting Li, Ehab S. Eshak, Renzhe Cui, Kokoro Shirai, Keyang Liu, Hiroyasu Iso, Satoyo Ikehara, Akiko Tamakoshi, Shigekazu Ukawa
    Cancer Research and Treatment.2021; 53(2): 497.     CrossRef
  • Association of job category and occupational activity with breast cancer incidence in Japanese female workers: the JACC study
    Gita Nirmala Sari, Ehab Salah Eshak, Kokoro Shirai, Yoshihisa Fujino, Akiko Tamakoshi, Hiroyasu Iso
    BMC Public Health.2020;[Epub]     CrossRef
  • Identification of NUF2 and FAM83D as potential biomarkers in triple-negative breast cancer
    Xiuming Zhai, Zhaowei Yang, Xiji Liu, Zihe Dong, Dandan Zhou
    PeerJ.2020; 8: e9975.     CrossRef
  • 7,341 View
  • 145 Download
  • 7 Web of Science
  • 6 Crossref
Close layer
Association between Body Mass Index and Gastric Cancer Risk According to Effect Modification by Helicobacter pylori Infection
Jieun Jang, Eun-Jung Cho, Yunji Hwang, Elisabete Weiderpass, Choonghyun Ahn, Jeoungbin Choi, Soung-Hoon Chang, Hai-Rim Shin, Min Kyung Lim, Keun-Young Yoo, Sue K. Park
Cancer Res Treat. 2019;51(3):1107-1116.   Published online November 21, 2018
DOI: https://doi.org/10.4143/crt.2018.182
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
Few studies investigated roles of body mass index (BMI) on gastric cancer (GC) risk according to Helicobacter pylori infection status. This study was conducted to evaluate associations between BMI and GC risk with consideration of H. pylori infection information.
Materials and Methods
We performed a case-cohort study (n=2,458) that consists of a subcohort, (n=2,193 including 67 GC incident cases) randomly selected from the Korean Multicenter Cancer Cohort (KMCC) and 265 incident GC cases outside of the subcohort. H. pylori infection was assessed using an immunoblot assay. GC risk according to BMI was evaluated by calculating hazard ratios (HRs) and their 95% confidence intervals (95% CIs) using weighted Cox hazard regression model.
Results
Increased GC risk in lower BMI group (< 23 kg/m2) with marginal significance, (HR, 1.32; 95% CI, 0.98 to 1.77) compared to the reference group (BMI of 23-24.9 kg/m2) was observed. In the H. pylori non-infection, both lower (< 23 kg/m2) and higher BMI (≥ 25 kg/m2) showed non-significantly increased GC risk (HR, 10.82; 95% CI, 1.25 to 93.60 and HR, 11.33; 95% CI, 1.13 to 113.66, respectively). However, these U-shaped associations between BMI and GC risk were not observed in the group who had ever been infected by H. pylori.
Conclusion
This study suggests the U-shaped associations between BMI and GC risk, especially in subjects who had never been infected by H. pylori.

Citations

Citations to this article as recorded by  
  • Ethnic-specific associations between body mass index and gastric cancer: a Mendelian randomization study in European and Korean populations
    Sangjun Lee, Sue K. Park
    Gastric Cancer.2024; 27(1): 19.     CrossRef
  • Cross-phenotype association analysis of gastric cancer: in-silico functional annotation based on the disease–gene network
    Sangjun Lee, Han-Kwang Yang, Hyuk-Joon Lee, Do Joong Park, Seong-Ho Kong, Sue K. Park
    Gastric Cancer.2023; 26(4): 517.     CrossRef
  • Association between metabolic syndrome and gastric cancer risk: results from the Health Examinees Study
    Dan Huang, Woo-Kyoung Shin, Katherine De la Torre, Hwi-Won Lee, Sukhong Min, Aesun Shin, Jong-Koo Lee, Daehee Kang
    Gastric Cancer.2023; 26(4): 481.     CrossRef
  • Cancer Progress and Priorities: Gastric Cancer
    Priya Alagesan, Jessica C. Goodwin, Katherine S. Garman, Meira Epplein
    Cancer Epidemiology, Biomarkers & Prevention.2023; 32(4): 473.     CrossRef
  • Obesity at early adulthood increases risk of gastric cancer from the Health Examinees-Gem (HEXA-G) study
    Hwi-Won Lee, Dan Huang, Woo-Kyoung Shin, Katherine de la Torre, Jae Jeong Yang, Minkyo Song, Aesun Shin, Jong-koo Lee, Daehee Kang, Shengxu Li
    PLOS ONE.2022; 17(2): e0260826.     CrossRef
  • Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants
    Jieun Jang, Sangjun Lee, Kwang-Pil Ko, Sarah K. Abe, Md. Shafiur Rahman, Eiko Saito, Md. Rashedul Islam, Norie Sawada, Xiao-Ou Shu, Woon-Puay Koh, Atsuko Sadakane, Ichiro Tsuji, Jeongseon Kim, Isao Oze, Chisato Nagata, Shoichiro Tsugane, Hui Cai, Jian-Min
    Cancer Epidemiology, Biomarkers & Prevention.2022; 31(9): 1727.     CrossRef
  • Impact of a Fermented High-Fiber Rye Diet on Helicobacter pylori and Cardio-Metabolic Risk Factors: A Randomized Controlled Trial Among Helicobacter pylori-Positive Chinese Adults
    Kun Xue, Yuwei Liu, Kia Nøhr Iversen, Mohsen Mazidi, Zheng Qu, Chenglin Dong, Tayi Jin, Göran Hallmans, Per Åman, Anders Johansson, Gengsheng He, Rikard Landberg
    Frontiers in Nutrition.2021;[Epub]     CrossRef
  • Current therapeutic options for gastric adenocarcinoma
    C.R. Akshatha, Smitha Bhat, R. Sindhu, Dharini Shashank, Sarana Rose Sommano, Wanaporn Tapingkae, Ratchadawan Cheewangkoon, Shashanka K. Prasad
    Saudi Journal of Biological Sciences.2021; 28(9): 5371.     CrossRef
  • The U‐shaped association between body mass index and gastric cancer risk in the Helicobacter pylori Biomarker Cohort Consortium: A nested case–control study from eight East Asian cohort studies
    Jieun Jang, Tianyi Wang, Hui Cai, Fei Ye, Gwen Murphy, Taichi Shimazu, Philip R Taylor, You‐Lin Qiao, Keun‐Young Yoo, Sun Ha Jee, Jeongseon Kim, Sheau‐Chiann Chen, Christian C Abnet, Shoichiro Tsugane, Wei Zheng, Xiao‐Ou Shu, Michael Pawlita, Sue K. Park,
    International Journal of Cancer.2020; 147(3): 777.     CrossRef
  • 13,119 View
  • 286 Download
  • 9 Web of Science
  • 9 Crossref
Close layer
Effectiveness of Gastric Cancer Screening on Gastric Cancer Incidence and Mortality in a Community-Based Prospective Cohort
Heewon Kim, Yunji Hwang, Hokyung Sung, Jieun Jang, Choonghyun Ahn, Sang Gyun Kim, Keun-Young Yoo, Sue K. Park
Cancer Res Treat. 2018;50(2):582-589.   Published online June 9, 2017
DOI: https://doi.org/10.4143/crt.2017.048
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
This study was performed to investigate the effectiveness of gastric cancer (GC) screening methods in a community-based prospective cohort of the Korean Multi-center Cancer Cohort (KMCC) with over a 10-year follow-up.
Materials and Methods
A total 10,909 and 4,773 subjects from the KMCC with information on gastroendoscopy (GE) and upper gastrointestinal series (UGIS) were included in this study. Cox proportional hazard model adjusted for age, sex, Helicobacter pylori infection, cigarette smoking, and alcohol drinking was used to estimate the hazard ratios (HRs) and 95% confidence interval (CI).
Results
The GE screened subjects had almost half the risk of GC-specific death than that of unscreened subjects (HR, 0.58; 95% CI, 0.36 to 0.94). Among the GC patients, GE screenees had a 2.24-fold higher survival rate than that of the non-screenees (95% CI, 1.61 to 3.11). In particular, GE screenees who underwent two or more screening episodes had a higher survival rate than that of the non-screenees (HR, 13.11; 95% CI, 7.38 to 23.30). The effectiveness of GE screening on reduced GC mortality and increased survival rate of GC patients was better in elderly subjects (≥ 65 years old) (HR, 0.47; 95% CI, 0.24 to 0.95 and HR, 8.84; 95% CI, 3.63 to 21.57, respectively) than that in younger subjects (< 65 years old) (HR, 0.66; 95% CI, 0.34 to 1.29 and HR, 1.83; 95% CI, 1.24 to 2.68, respectively). In contrast, UGIS screening had no significant relation to GC mortality and survival.
Conclusion
The findings of this study suggest that a decreased GC-specific mortality and improved survival rate in GC patients can be achieved through GE screening.

Citations

Citations to this article as recorded by  
  • Inhibition of TAF1B impairs ribosome biosynthesis and suppresses cell proliferation in stomach adenocarcinoma through promoting c-MYC mRNA degradation
    Hang-fei Chen, Zhang-ping Li, Qi Wu, Chun Yu, Jing-Yi Yan, Yong-feng Bai, Sheng-mei Zhu, Mao-xiang Qian, Ming Liu, Li-feng Xu, Zheng Peng, Feng Zhang
    Heliyon.2024; 10(1): e23167.     CrossRef
  • Cumulative exposure to impaired fasting glucose and gastrointestinal cancer risk: A nationwide cohort study
    Byeong Yun Ahn, Bokyung Kim, Sanghyun Park, Sang Gyun Kim, Kyungdo Han, Soo‐Jeong Cho
    Cancer.2024; 130(10): 1807.     CrossRef
  • Gastric cancer screening in Western countries: A call to action
    Fabio Farinati, Filippo Pelizzaro
    Digestive and Liver Disease.2024; 56(10): 1653.     CrossRef
  • The Role of Screening and Early Detection in Upper Gastrointestinal Cancers
    Jin Woo Yoo, Monika Laszkowska, Robin B. Mendelsohn
    Hematology/Oncology Clinics of North America.2024; 38(3): 693.     CrossRef
  • Evaluation of the value of combined detection of tumor markers CA724, carcinoembryonic antigen, CA242, and CA19-9 in gastric cancer
    Chong-Mei Zhou, Shao-Hua Zhao
    World Journal of Gastrointestinal Oncology.2024; 16(5): 1737.     CrossRef
  • Global incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035
    Ju-Li Lin, Jian-Xian Lin, Guang-Tan Lin, Chang-Ming Huang, Chao-Hui Zheng, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Ping Li
    BMC Public Health.2024;[Epub]     CrossRef
  • Gastric intestinal metaplasia regression in United States population: A retrospective longitudinal study
    Akram I Ahmed, Ahmed El Sabagh, Claire Caplan, Arielle Lee, Won K Cho
    JGH Open.2024;[Epub]     CrossRef
  • Performance of the National Cancer Screening Program for Gastric Cancer in Korea
    Young-Il Kim
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2024; 24(3): 231.     CrossRef
  • MicroRNA-155 and its exosomal form: Small pieces in the gastrointestinal cancers puzzle
    Jinbao Guo, Li Zhong, Mohammad Reza Momeni
    Cell Biology and Toxicology.2024;[Epub]     CrossRef
  • Clinicopathological and prognostic significance of TIMP1 expression in gastric cancer: a systematic review and meta-analysis
    Mingcan Zheng, Puxu Wang, Yuhang Wang, Zirui Jia, Jiacheng Gao, Xiaodong Tan, Hailong Chen, Guo Zu
    Expert Review of Anticancer Therapy.2024; 24(11): 1169.     CrossRef
  • Fecal Immunochemical Test and Helicobacter pylori Stool Antigen Co-Testing
    M. Constanza Camargo
    JAMA.2024; 332(19): 1621.     CrossRef
  • Knowledge and practice of early gastric cancer screening among adults aged ≥ 45 years in China: a cross-sectional study
    Xiaoci He, Wei Qi, Qian Wang, Shuping Zhao
    BMC Public Health.2024;[Epub]     CrossRef
  • Inadequate gastric preparation and its associated factors for magnetically controlled capsule endoscopy
    Qing-Zhou Kong, Cheng Peng, Zhen Li, Bao-Ling Tian, Yue-Yue Li, Fei-Xue Chen, Xiu-Li Zuo, Yan-Qing Li
    Frontiers in Pharmacology.2023;[Epub]     CrossRef
  • Clinicopathologic significance of Her-2 and P53 expressions in gastric cancer
    Xiaoyu Zhang, Mingchuan Wang, Yizhuo Wang, Xianbin Cheng, Yang Jiang, Huijie Xiao
    Asian Journal of Surgery.2023; 46(1): 526.     CrossRef
  • Trend of gastric cancer incidence and death rate in adolescents and young adults: A retrospective cohort study based on the Surveillance, Epidemiology, and End Results (SEER) database
    Jie Wen, Huiqin Shen
    Journal of Gastroenterology and Hepatology.2023; 38(3): 393.     CrossRef
  • Metachronous gastric neoplasm beyond 5 years after endoscopic resection for early gastric cancer
    Eunwoo Lee, Sang Gyun Kim, Bokyung Kim, Jue Lie Kim, Jung Kim, Hyunsoo Chung, Soo-Jeong Cho
    Surgical Endoscopy.2023; 37(5): 3901.     CrossRef
  • Gastric cancer clinical characteristics and their altered trends in South China: An epidemiological study with 2,800 cases spanning 26 years
    Hongfa Wei, Xiao-Yong Zhan, Xianying Liao, Wenchao Li, Hui Chen, Cuncan Deng, Xinghan Jin, Zhangsen Huang, Mo Yang, Changhua Zhang, Yulong He
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • Controlling Gastric Cancer in a World of Heterogeneous Risk
    Robert J. Huang, Monika Laszkowska, Haejin In, Joo Ha Hwang, Meira Epplein
    Gastroenterology.2023; 164(5): 736.     CrossRef
  • Willingness to Undergo Gastroscopy for Early Gastric Cancer Screening and Its Associated Factors During the COVID-19 Pandemic – A Nationwide Cross-Sectional Study in China
    Kejia Ma, Xuejie Chen, Xin Xiang, Xueyi Mao, Ningxin Zhu, Tianyu Wang, Shuyu Ye, Xiaoyan Wang, Minzi Deng
    Patient Preference and Adherence.2023; Volume 17: 505.     CrossRef
  • Radiographic and endoscopic screening to reduce gastric cancer mortality: a systematic review and meta-analysis
    Masaya Hibino, Chisato Hamashima, Mitsunaga Iwata, Teruhiko Terasawa
    The Lancet Regional Health - Western Pacific.2023; 35: 100741.     CrossRef
  • Screening behaviors and related factors among the first-degree relatives of Chinese patients with gastric cancer
    Min Zhao, Hui Li, Hui Ren, Jie Zhang, Hong Yang, Yuhan Lu
    Asia-Pacific Journal of Oncology Nursing.2023; 10(5): 100220.     CrossRef
  • ALDOC regulated the biological function and immune infiltration of gastric cancer cells
    Liqiao Chen, Yi Zeng, Baoqing Ren, Xinyu Wang, Fucheng Zhao, Jitao Du, Rupeng Zhang, Jingyu Deng
    The International Journal of Biochemistry & Cell Biology.2023; 158: 106407.     CrossRef
  • Gastric Cancer Biomarker Candidates Identified by Machine Learning and Integrative Bioinformatics: Toward Personalized Medicine
    Vigneshwar Suriya Prakash Sinnarasan, Dahrii Paul, Rajesh Das, Amouda Venkatesan
    OMICS: A Journal of Integrative Biology.2023; 27(6): 260.     CrossRef
  • Endoscopic evaluation by the Kyoto classification of gastritis combined with serum anti-Helicobacter pylori antibody testing reliably risk-stratifies subjects in a population-based gastric cancer screening program
    Ryosuke Hirai, Mami Hirai, Motoyuki Otsuka, Toshiharu Mitsuhashi, Yuichi Shimodate, Hirokazu Mouri, Kazuhiro Matsueda, Hiroshi Yamamoto, Motowo Mizuno
    Journal of Gastroenterology.2023; 58(9): 848.     CrossRef
  • Determinants of gastric cancer screening attendance in Southeastern China: a cross-sectional study
    Zhiwen Huang, Zhijian Hu, Li Ping Wong, Yulan Lin
    BMJ Open.2023; 13(7): e073925.     CrossRef
  • LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis
    Jie Wang, Dongxiao Shen, Shichao Li, Qiuying Li, Qingsong Zuo, Jiahao Lu, Donghao Tang, Yuejiao Feng, Peihao Yin, Chao Chen, Teng Chen
    Cancer Gene Therapy.2023; 30(11): 1530.     CrossRef
  • FIS1 Overexpression Is Correlated with Tumor Metastasis in Gastric Adenocarcinoma
    Dariush Karimi, Negar Pedram, Farzad Kakaei, Milad Asadi, Elham Poursaei, Touraj Asvadi Kermani
    Journal of Gastrointestinal Cancer.2022; 53(2): 466.     CrossRef
  • An Approach to the Primary and Secondary Prevention of Gastric Cancer in the United States
    Robert J. Huang, Meira Epplein, Chisato Hamashima, Il Ju Choi, Eunjung Lee, Dennis Deapen, Yanghee Woo, Thuy Tran, Shailja C. Shah, John M. Inadomi, David A. Greenwald, Joo Ha Hwang
    Clinical Gastroenterology and Hepatology.2022; 20(10): 2218.     CrossRef
  • Thrombospondin-2 holds prognostic value and is associated with metastasis and the mismatch repair process in gastric cancer
    Xiao-dong Chu, Zheng-bin Lin, Ting Huang, Hui Ding, Yi-ran Zhang, Zhan Zhao, Shu-chen Huangfu, Sheng-hui Qiu, Yan-guan Guo, Xiao-li Chu, Jing-hua Pan, Yun-long Pan
    BMC Cancer.2022;[Epub]     CrossRef
  • Beneficial effects of endoscopic screening on gastric cancer and optimal screening interval: a population-based study
    Wen-Qing Li, Xiang-Xiang Qin, Zhe-Xuan Li, Le-Hua Wang, Zong-Chao Liu, Xiao-Han Fan, Li-Hui Zhang, Yi Li, Xiu-Zhen Wu, Jun-Ling Ma, Yang Zhang, Lan-Fu Zhang, Ming Li, Tong Zhou, Jing-Ying Zhang, Jian-Xi Wang, Wei-Dong Liu, Wei-Cheng You, Kai-Feng Pan
    Endoscopy.2022; 54(09): 848.     CrossRef
  • Current status of the gastric cancer screening program in Korea
    Young-Il Kim, Il Ju Choi
    Journal of the Korean Medical Association.2022; 65(5): 250.     CrossRef
  • Gastric hydrodistension CT versus CT without gastric distension in preoperative TN staging of gastric carcinoma: analysis of single-center cancer registry
    Yu-Hsien Lee, Wen-Hui Chan, Ying-Chieh Lai, An-Hsin Chen, Chien-Ming Chen
    Scientific Reports.2022;[Epub]     CrossRef
  • Small molecules as potential biomarkers of early gastric cancer: A mass spectrometry imaging approach
    Long Zou, Luolin Wang, Lei Guo, Weixun Zhou, Zhizhen Lai, Cheng Zhu, Xi Wu, Zhili Li, Aiming Yang
    Clinica Chimica Acta.2022; 534: 35.     CrossRef
  • Gastric cancer incidence, mortality and burden in adolescents and young adults: a time-trend analysis and comparison among China, South Korea, Japan and the USA
    Si Lin Wu, Yao Zhang, Yi Fu, Jian Li, Ji Sheng Wang
    BMJ Open.2022; 12(7): e061038.     CrossRef
  • Current Evidence for a Paradigm Shift in Gastric Cancer Prevention From Endoscopic Screening toHelicobacter pyloriEradication in Korea
    Young-Il Kim, Il Ju Choi
    Journal of Gastric Cancer.2022; 22(3): 169.     CrossRef
  • Effectiveness of endoscopic screening for gastric cancer: The Japan Public Health Center‐based Prospective Study
    Nobuhiro Narii, Tomotaka Sobue, Ling Zha, Tetsuhisa Kitamura, Motoki Iwasaki, Manami Inoue, Taiki Yamaji, Shoichiro Tsugane, Norie Sawada
    Cancer Science.2022; 113(11): 3922.     CrossRef
  • The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway
    Tuoyang Li, Junyi Zhou, Yingming Jiang, Yandong Zhao, Jintuan Huang, Weiyao Li, Zhenze Huang, Zijian Chen, Xiaocheng Tang, Hao Chen, Zuli Yang
    International Journal of Molecular Sciences.2022; 23(19): 11022.     CrossRef
  • Urine proteomic signatures predicting the progression from premalignancy to malignant gastric cancer
    Hua Fan, Xue Li, Zhong-Wu Li, Nai-Ren Zheng, Li-Hua Cao, Zong-Chao Liu, Ming-Wei Liu, Kai Li, Wen-Hui Wu, Zhe-Xuan Li, Tong Zhou, Yang Zhang, Wei-Dong Liu, Lan-Fu Zhang, Wei-Cheng You, Yi Wang, Jianmin Wu, Kai-Feng Pan, Jun Qin, Wen-Qing Li
    eBioMedicine.2022; 86: 104340.     CrossRef
  • Forthcoming Step in Gastric Cancer Prevention: How Can Risk Stratification Be Combined with Endoscopic Screening for Gastric Cancer?
    Chisato Hamashima
    Gut and Liver.2022; 16(6): 811.     CrossRef
  • Survival of gastric cancer in China from 2000 to 2022: A nationwide systematic review of hospital-based studies
    Houqiang Li, Han Zhang, Hujia Zhang, Youxin Wang, Xiaobing Wang, Haifeng Hou
    Journal of Global Health.2022;[Epub]     CrossRef
  • Optimal extent of lymph node dissection in gastric cancer
    Zsolt Varga, Péter Kolozsi, Kitti Nagy, Dezső Tóth
    Frontiers in Surgery.2022;[Epub]     CrossRef
  • Urine Proteomic Signatures Predicting the Progression from Premalignancy to Malignant Gastric Cancer
    Hua Fan, Xue Li, Zhong-Wu Li, Nai-Ren Zheng, Li-Hua Cao, Zong-Chao Liu, Yi Wang, Ming-Wei Liu, Kai Li, Wen-Hui Wu, Zhe-Xuan Li, Tong Zhou, Yang Zhang, Wei-Dong Liu, Lan-Fu Zhang, Wei-Cheng You, Jianmin Wu, Kai-Feng Pan, Jun Qin, Wen-Qing Li
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Disaggregated mortality from gastrointestinal cancers in Asian Americans: Analysis of United States death records
    Robert J. Huang, Nora Sharp, Ruth Talamoa, Kristopher Kapphahn, Vedant Sathye, Bryant Lin, Malathi Srinivasan, Latha P. Palaniappan
    International Journal of Cancer.2021; 148(12): 2954.     CrossRef
  • Gastrointestinal cancers in China, the USA, and Europe
    Yumo Xie, Lishuo Shi, Xiaosheng He, Yanxin Luo
    Gastroenterology Report.2021; 9(2): 91.     CrossRef
  • Endoscopic Screening and Surveillance for Gastric Cancer
    Bokyung Kim, Soo-Jeong Cho
    Gastrointestinal Endoscopy Clinics of North America.2021; 31(3): 489.     CrossRef
  • Improvement in the Mortality-to-Incidence Ratios for Gastric Cancer in Developed Countries With High Health Expenditures
    Tzu-Wei Yang, Chi-Chih Wang, Wei-Cheng Hung, Yu-Hsiang Liu, Wen-Wei Sung, Ming-Chang Tsai
    Frontiers in Public Health.2021;[Epub]     CrossRef
  • Extended Gastrectomy for T4b Gastric Adenocarcinoma: Single-Surgeon Experience
    Mushegh А. Sahakyan, Artak Gabrielyan, Hmayak Petrosyan, Shushan Yesayan, Sevak S. Shahbazyan, Arthur M. Sahakyan
    Journal of Gastrointestinal Cancer.2020; 51(1): 135.     CrossRef
  • Laparoscopic management of gastric remnant ischemia after laparoscopic distal gastrectomy with Billroth-I anastomosis—A case report
    Abdulaziz Alshehri, Hee-sung Kim, Byung Sik Kim
    International Journal of Surgery Case Reports.2020; 66: 265.     CrossRef
  • Modeling the Surface Field From an Ingested Radio Transmitter With an Approximate Attenuation Model for Gastroenterology Investigations
    Yana A. Salchak, Hugo G. Espinosa, David V. Thiel
    IEEE Transactions on Biomedical Engineering.2020; 67(2): 504.     CrossRef
  • The long-term population impact of endoscopic screening programmes on disease burdens of gastric cancer in China: A mathematical modelling study
    Mingwang Shen, Ruyi Xia, Zheng Luo, Hongmei Zeng, Wenqiang Wei, Guihua Zhuang, Lei Zhang, Wanqing Chen
    Journal of Theoretical Biology.2020; 484: 109996.     CrossRef
  • CD40 DNA hypermethylation in primary gastric tumors; as a novel diagnostic biomarker
    Mohammad Amini, Khodayar Ghorban, Ahad Mokhtarzadeh, Maryam Dadmanesh, Behzad Baradaran
    Life Sciences.2020; 254: 117774.     CrossRef
  • Bio-assay of the non-amidated progastrin-derived peptide (G17-Gly) using the tailor-made recombinant antibody fragment and phage display method: a biomedical analysis
    Deniz Sadighbayan, Mohammad Reza Tohidkia, Tayebeh Mehdipour, Mohammad Hasanzadeh, Ahmad Yari Khosroushahi
    Analytical Methods.2020; 12(21): 2735.     CrossRef
  • A protocol of systematic review and meta-analysis of narrow band imaging endoscopy in detection of early gastric cancer
    Li Zhang, Xiao-yu Liu, Gang Zhong, Zhi Xin, Xiang-Yu Sun, Zhen-Yu Wang
    Medicine.2020; 99(33): e21420.     CrossRef
  • Gastric cancer
    Elizabeth C Smyth, Magnus Nilsson, Heike I Grabsch, Nicole CT van Grieken, Florian Lordick
    The Lancet.2020; 396(10251): 635.     CrossRef
  • Development and external validation of a nomogram to predict the risk of Upper gastrointestinal precancerous lesions in a non‐high‐incidence area
    Hai‐Fan Xiao, Shi‐Peng Yan, Ji‐Gang Li, Zhao‐Hui Shi, Yan‐Hua Zou, Ke‐Kui Xu, Xian‐Zhen Liao
    Cancer Medicine.2020; 9(22): 8722.     CrossRef
  • The Clinicopathological Features and Staging at Presentation of Gastric Cancer: A Single-Center Retrospective Study
    Syn Yi Chong, Soo Fan Ang
    Asian Journal of Oncology.2020; 06: 120.     CrossRef
  • Initial results from a multi-center population-based cluster randomized trial of esophageal and gastric cancer screening in China
    Hongmei Zeng, Kexin Sun, Maomao Cao, Rongshou Zheng, Xibin Sun, Shuzheng Liu, Zhiyi Zhang, Yuqin Liu, Guizhou Guo, Guohui Song, Yigong Zhu, Xianghong Wu, Bingbing Song, Xianzhen Liao, Yanfang Chen, Mingyang Song, Edward Giovannucci, Guihua Zhuang, Wenqian
    BMC Gastroenterology.2020;[Epub]     CrossRef
  • Gastric Mucosal Atrophy Impedes Housekeeping Gene Methylation in Gastric Cancer Patients
    Jung-Hwan Oh, Mun-Gan Rhyu, Suk-Il Kim, Mi-Ri Yun, Jung-Ha Shin, Seung-Jin Hong
    Cancer Research and Treatment.2019; 51(1): 267.     CrossRef
  • Gastric Cancer – From Aetiology to Management: Differences Between the East and the West
    W.L. Chan, K.O. Lam, V.H.F. Lee, M. Davidson, T.H. So, J.S. Li, I. Chau, D.L.W. Kwong
    Clinical Oncology.2019; 31(8): 570.     CrossRef
  • Using big data to see the forest and the trees: endoscopic submucosal dissection of early gastric cancer in Korea
    Chang Seok Bang, Gwang Ho Baik
    The Korean Journal of Internal Medicine.2019; 34(4): 772.     CrossRef
  • Review and Comparison of Cancer Biomarker Trends in Urine as a Basis for New Diagnostic Pathways
    Carmen Bax, Beatrice Julia Lotesoriere, Selena Sironi, Laura Capelli
    Cancers.2019; 11(9): 1244.     CrossRef
  • Awareness of risk factors and warning symptoms and attitude towards gastric cancer screening among the general public in China: a cross-sectional study
    Qi Liu, Xi Zeng, Wen Wang, Ruo-lin Huang, Yan-jin Huang, Shan Liu, Ying-hui Huang, Ying-xin Wang, Qing-hong Fang, Guoping He, Ying Zeng
    BMJ Open.2019; 9(7): e029638.     CrossRef
  • Preoperative gastric lavage in gastric cancer patients undergoing surgical, endoscopic or minimally invasive treatment: An oncological measure preventing peritoneal spillage of intragastric cancer cells and development of related metastases
    Edoardo Virgilio, Genoveffa Balducci, Paolo Mercantini, Enrico Giarnieri, Maria Rosaria Giovagnoli, Monica Montagnini, Antonella Proietti, Rosaria D'Urso, Marco Cavallini
    Medical Hypotheses.2018; 114: 30.     CrossRef
  • Endoscopic Screening in Asian Countries Is Associated With Reduced Gastric Cancer Mortality: A Meta-analysis and Systematic Review
    Xing Zhang, Meng Li, Shuntai Chen, Jiaqi Hu, Qiujun Guo, Rui Liu, Honggang Zheng, Zhichao Jin, Yuan Yuan, Yupeng Xi, Baojin Hua
    Gastroenterology.2018; 155(2): 347.     CrossRef
  • Screening for gastric cancer with magnetically controlled capsule gastroscopy in asymptomatic individuals
    An-Jing Zhao, Yang-Yang Qian, Hui Sun, Xi Hou, Jun Pan, Xiao Liu, Wei Zhou, Yi-Zhi Chen, Xi Jiang, Zhao-Shen Li, Zhuan Liao
    Gastrointestinal Endoscopy.2018; 88(3): 466.     CrossRef
  • Changing trends in clinico-pathologic characteristics and treatment outcomes in patients with gastric cancer: A single-center, public hospital, retrospective study
    Min-Seung Gwak, Jong-Min Park
    Korean Journal of Clinical Oncology.2018; 14(2): 69.     CrossRef
  • 11,093 View
  • 430 Download
  • 67 Web of Science
  • 66 Crossref
Close layer
Light Alcohol Drinking and Risk of Cancer: A Meta-Analysis of Cohort Studies
Yoon-Jung Choi, Seung-Kwon Myung, Ji-Ho Lee
Cancer Res Treat. 2018;50(2):474-487.   Published online May 22, 2017
DOI: https://doi.org/10.4143/crt.2017.094
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Purpose
The purpose of this study was to determine whether light alcohol drinking increases the risk of cancer by using a meta-analysis of cohort studies because the newly revised 2015 European Code against Cancer fourth edition on alcohol and cancer was based on critical flaws in the interpretation and citation of the previous meta-analyses.
Materials and Methods
PubMed and EMBASE were searched in April, 2016. Two authors independently reviewed and selected cohort studies on the association between very light (≤ 0.5 drink/day), light (≤ 1 drink/day), or moderate drinking (1-2 drinks/day) and the risk of cancer incidence and mortality. A pooled relative riskwith its 95% confidence intervalwas calculated by a randomeffects meta-analysis. Main outcome measures were cancer incidence and mortality.
Results
A total of 60 cohort studies from 135 articles were included in the final analysis. Very light drinking or light drinking was not associated with the incidence of most cancers except for female breast cancer in women and male colorectal cancer. Conversely, light drinking was associated with a decreased incidence of both female and male lung cancer significantly and both female and male thyroid cancer marginally significantly. Moderate drinking significantly increased the incidence of male colorectal cancer and female breast cancer,whereas it decreased the incidence of both female and male hematologic malignancy.
Conclusion
We found that very light or light alcohol drinking was not associated with the risk of most of the common cancers except for the mild increase in the incidence of breast cancer in women and colorectal cancer in men.

Citations

Citations to this article as recorded by  
  • Lung Cancer and Lifestyle Factors
    Jeta Bunjaku, Arber Lama, Tawanda Pesanayi, Jeton Shatri, Mary Chamberlin, Ilir Hoxha
    Hematology/Oncology Clinics of North America.2024; 38(1): 171.     CrossRef
  • Breast Cancer and Lifestyle Factors
    Ilir Hoxha, Fitim Sadiku, Lot Hoxha, Midhet Nasim, Marie Anne Christine Buteau, Krenare Grezda, Mary D. Chamberlin
    Hematology/Oncology Clinics of North America.2024; 38(1): 137.     CrossRef
  • Association between lifestyle and dietary preference factors and conventional adenomas and serrated polyps
    Jue Xu, Peihan Chi, Kang Qin, Biao Li, Zhongxue Cheng, Zhecong Yu, Caixia Jiang, Yunxian Yu
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • Predicting lung cancer survival prognosis based on the conditional survival bayesian network
    Lu Zhong, Fan Yang, Shanshan Sun, Lijie Wang, Hong Yu, Xiushan Nie, Ailing Liu, Ning Xu, Lanfang Zhang, Mingjuan Zhang, Yue Qi, Huaijun Ji, Guiyuan Liu, Huan Zhao, Yinan Jiang, Jingyi Li, Chengcun Song, Xin Yu, Liu Yang, Jinchao Yu, Hu Feng, Xiaolei Guo,
    BMC Medical Research Methodology.2024;[Epub]     CrossRef
  • Differential patterns of reproductive and lifestyle risk factors for breast cancer according to birth cohorts among women in China, Japan and Korea
    Salma Nabila, Ji-Yeob Choi, Sarah Krull Abe, Md Rashedul Islam, Md Shafiur Rahman, Eiko Saito, Aesun Shin, Melissa A. Merritt, Ryoko Katagiri, Xiao-Ou Shu, Norie Sawada, Akiko Tamakoshi, Ritsu Sakata, Atsushi Hozawa, Jeongseon Kim, Chisato Nagata, Sue K.
    Breast Cancer Research.2024;[Epub]     CrossRef
  • Design, synthesis, in silico, and pharmacological evaluation of novel quinoline derivatives containing substituted piperazine moieties as potential anti-breast cancer agents
    Muthiah Gnana Ruba Priya, Viswas Raja Solomon, Nagarajan Hemavathy, Jeyaraman Jeyakanthan, Dileep Kumar, Jahnavi Mahesh
    Results in Chemistry.2024; 7: 101359.     CrossRef
  • Sijunzi decoction enhances sensitivity of colon cancer cells to NK cell destruction by modulating P53 expression
    Xinxin Wang, Shufang Pan, Liangyan Chen, Chengchen Liang, Yueyi Zhu, Ke Zhou, Xiaolan Shi
    Journal of Ethnopharmacology.2024; 329: 118115.     CrossRef
  • The Lancet Breast Cancer Commission
    Charlotte E Coles, Helena Earl, Benjamin O Anderson, Carlos H Barrios, Maya Bienz, Judith M Bliss, David A Cameron, Fatima Cardoso, Wanda Cui, Prudence A Francis, Reshma Jagsi, Felicia Marie Knaul, Stuart A McIntosh, Kelly-Anne Phillips, Lukas Radbruch, M
    The Lancet.2024; 403(10439): 1895.     CrossRef
  • The Combined Effects of Alcohol Consumption and Smoking on Cancer Risk by Exposure Level: A Systematic Review and Meta-Analysis
    Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Non-genetic factors and breast cancer: an umbrella review of meta-analyses
    Anneza Yiallourou, Katerina Pantavou, Georgios Markozannes, Antonis Pilavas, Andrea Georgiou, Andria Hadjikou, Mary Economou, Neophytos Christodoulou, Konstantinos Letsos, Elina Khattab, Chrystalleni Kossyva, Maria Constantinou, Melanie Theodoridou, Danie
    BMC Cancer.2024;[Epub]     CrossRef
  • Sex difference in alcohol consumption associated with colorectal cancer risk in Quzhou, China: A nested case-control study
    Shi-Ming Lai, Hong-Hong Zhu, Zhi-Juan Gan, Bi-Yun Zheng, Zhao-Hui Xu, Zhi-Cheng Wang, Xiao-Fang Liao
    Preventive Medicine Reports.2024; 44: 102807.     CrossRef
  • Meaningful nomograms based on systemic immune inflammation index predicted survival in metastatic pancreatic cancer patients receiving chemotherapy
    Yanan Sun, Jiahe Hu, Rongfang Wang, Xinlian Du, Xiaoling Zhang, Jiaoting E, Shaoyue Zheng, Yuxin Zhou, Ruishu Mou, Xuedong Li, Hanbo Zhang, Ying Xu, Yuan Liao, Wenjie Jiang, Lijia Liu, Ruitao Wang, Jiuxin Zhu, Rui Xie
    Cancer Medicine.2024;[Epub]     CrossRef
  • Oncologists’ communication about tobacco and alcohol use during treatment for esophagogastric cancer: a qualitative observational study of simulated consultations
    Danique W. Bos-van den Hoek, Loïs F. van de Water, Pieter G. Vos, Meeke Hoedjes, Ruud Roodbeen, Bastiaan R. Klarenbeek, Debby Geijsen, Ellen M. A. Smets, Hanneke W. M. van Laarhoven, Inge Henselmans
    Supportive Care in Cancer.2024;[Epub]     CrossRef
  • The clinicopathological and prognostic significance of PSMD14 in cancers based on bioinformatics and meta-analysis
    Shu-Yi Dong, Shuxin Ding, Zhen Meng, Bo Zou
    Future Science OA.2024;[Epub]     CrossRef
  • Alcoholic beverage consumption and female breast cancer risk: A systematic review and meta‐analysis of prospective cohort studies
    Ivneet Sohi, Jürgen Rehm, Marian Saab, Lavanya Virmani, Ari Franklin, Gonzalo Sánchez, Mihojana Jhumi, Ahmed Irshad, Hiya Shah, Daniela Correia, Pietro Ferrari, Carina Ferreira‐Borges, Beatrice Lauby‐Secretan, Gauden Galea, Susan Gapstur, Maria Neufeld, H
    Alcohol, Clinical and Experimental Research.2024;[Epub]     CrossRef
  • Association of alcohol types, coffee and tea intake with mortality: prospective cohort study of UK Biobank participants
    Sylva M. Schaefer, Anna Kaiser, Inken Behrendt, Gerrit Eichner, Mathias Fasshauer
    British Journal of Nutrition.2023; 129(1): 115.     CrossRef
  • Magazines as contradictory spaces for alcohol messaging: a mixed method content and thematic analysis of UK women’s magazine representations of alcohol and its consumption
    A. M. Atkinson, B. R. Meadows, K. M. Ross-Houle, C. Smith, H. R. Sumnall
    Drugs: Education, Prevention and Policy.2023; 30(5): 474.     CrossRef
  • Sweetened beverages are associated with a higher risk of differentiated thyroid cancer in the EPIC cohort: a dietary pattern approach
    Raul Zamora-Ros, Valerie Cayssials, Ramon Clèries, Maria Torrents, Graham Byrnes, Elisabete Weiderpass, Maria Sandström, Martin Almquist, Marie-Christine Boutron-Ruault, Anne Tjønneland, Cecilie Kyrø, Verena A. Katzke, Charlotte Le Cornet, Giovanna Masala
    European Journal of Nutrition.2023; 62(1): 105.     CrossRef
  • Designing Effective Alcohol Warnings: Consumer Reactions to Icons and Health Topics
    Anna H. Grummon, Phoebe R. Ruggles, Thomas K. Greenfield, Marissa G. Hall
    American Journal of Preventive Medicine.2023; 64(2): 157.     CrossRef
  • Reinstating apoptosis using putative Bcl-xL natural product inhibitors: Molecular docking and ADMETox profiling investigations
    Ibrahim Damilare Boyenle, Abdeen Tunde Ogunlana, Abdul-Quddus Kehinde Oyedele, Babatunde Kazeem Olokodana, Nurudeen Owolabi, Abdulmalik Salahudeen, Oluwafemi Timothy Aderenle, Taiwo Oluwafisayomi Oloyede, Temitope Isaac Adelusi
    Journal of Taibah University Medical Sciences.2023; 18(3): 461.     CrossRef
  • Cancer Risk According to Alcohol Consumption Trajectories: A Population-based Cohort Study of 2.8 Million Korean Men
    Thi Tra Bui, Minji Han, Ngoc Minh Luu, Thi Phuong Thao Tran, Min Kyung Lim, Jin-Kyoung Oh
    Journal of Epidemiology.2023; 33(12): 624.     CrossRef
  • A Brief Intervention for Improving Alcohol Literacy and Addressing Harmful Alcohol Use Among Women Attending an Australian Breast Screening Service (Health4her): Protocol for a Hybrid Effectiveness-Implementation Trial
    Jasmin Grigg, Victoria Manning, Darren Lockie, Michelle Giles, Robin Bell, Peta Stragalinos, Chloe Bernard, Isabelle Volpe, Christopher J Greenwood, Liam Smith, Peter Bragge, Dan I Lubman
    JMIR Research Protocols.2023; 12: e44867.     CrossRef
  • Moderate wine consumption and cancer risk in context
    Ursula Fradera, Claudia Hammer, P. Roca
    BIO Web of Conferences.2023; 56: 04002.     CrossRef
  • Systemic treatment for metastatic colorectal cancer
    Wattana Leowattana, Pathomthep Leowattana, Tawithep Leowattana
    World Journal of Gastroenterology.2023; 29(10): 1425.     CrossRef
  • Systemic treatment for metastatic colorectal cancer
    Wattana Leowattana, Pathomthep Leowattana, Tawithep Leowattana
    World Journal of Gastroenterology.2023; 29(10): 1569.     CrossRef
  • Why Does Obesity as an Inflammatory Condition Predispose to Colorectal Cancer?
    Anna Maria Rychter, Liliana Łykowska-Szuber, Agnieszka Zawada, Aleksandra Szymczak-Tomczak, Alicja Ewa Ratajczak, Kinga Skoracka, Michalina Kolan, Agnieszka Dobrowolska, Iwona Krela-Kaźmierczak
    Journal of Clinical Medicine.2023; 12(7): 2451.     CrossRef
  • Risky alcohol consumption among women in Australia attending breast screening services: an exploratory cross‐sectional study
    Jasmin Grigg, Victoria Manning, Ali Cheetham, Christopher J. Greenwood, George Youssef, Darren Lockie, Robin Bell, Peta Stragalinos, Chloe Bernard, Dan I. Lubman
    Addiction.2023; 118(8): 1493.     CrossRef
  • Alcohol consumption and all-cause and cause-specific mortality among US adults: prospective cohort study
    Yalan Tian, Jiahui Liu, Yue Zhao, Nana Jiang, Xiao Liu, Gang Zhao, Xia Wang
    BMC Medicine.2023;[Epub]     CrossRef
  • A brief intervention for improving alcohol literacy and reducing harmful alcohol use by women attending a breast screening service: a randomised controlled trial
    Jasmin Grigg, Victoria Manning, Darren Lockie, Michelle Giles, Robin J Bell, Peta Stragalinos, Chloe Bernard, Christopher J Greenwood, Isabelle Volpe, Liam Smith, Peter Bragge, Dan I Lubman
    Medical Journal of Australia.2023; 218(11): 511.     CrossRef
  • Associations between Liver Enzymes, Lifestyle Risk Factors and Pre-Existing Medical Conditions in a Population-Based Cross-Sectional Sample
    Onni Niemelä, Aini Bloigu, Risto Bloigu, Mauri Aalto, Tiina Laatikainen
    Journal of Clinical Medicine.2023; 12(13): 4276.     CrossRef
  • Gut Microbiota and Colorectal Cancer Risk Factors
    Hadi Feizi, Mohammad Ahangarzadeh Rezaee, Reza Ghotaslou, Mohammad Sadrkabir, Farhad Jadidi-Niaragh, Pourya Gholizadeh, Sepehr Taghizadeh, Khudaverdi Ghanbarov, Mehdi Yousefi, Hossein Samadi Kafil
    Current Pharmaceutical Biotechnology.2023; 24(8): 1018.     CrossRef
  • Effect of alcohol consumption on breast cancer: probabilistic bias analysis for adjustment of exposure misclassification bias and confounders
    Reza Pakzad, Saharnaz Nedjat, Hamid Salehiniya, Nasrin Mansournia, Mahyar Etminan, Maryam Nazemipour, Iraj Pakzad, Mohammad Ali Mansournia
    BMC Medical Research Methodology.2023;[Epub]     CrossRef
  • Food Intake and Colorectal Cancer
    Akshaya Kumar, Shanmugavel Chinnathambi, Magi Kumar, Ganesh N. Pandian
    Nutrition and Cancer.2023; 75(9): 1710.     CrossRef
  • Shared Lifestyle-Related Risk Factors of Cardiovascular Disease and Cancer: Evidence for Joint Prevention
    Farzad Masoudkabir, Noushin Mohammadifard, Arya Mani, Andrew Ignaszewski, Margot K. Davis, Golnaz Vaseghi, Marjan Mansourian, Christopher Franco, Carolyn Gotay, Nizal Sarrafzadegan, Francesco Giallauria
    The Scientific World Journal.2023; 2023: 1.     CrossRef
  • Alcohol and cancer: a denied association the statement of the Italian society on alcohol (Società Italiana di Alcologia—SIA)
    Gianni Testino, Emanuele Scafato, Valentino Patussi, Patrizia Balbinot, Andrea Ghiselli, Fabio Caputo
    Alcohol and Alcoholism.2023; 58(6): 683.     CrossRef
  • Diet-Wide Association, Genetic Susceptibility and Colorectal Cancer Risk: A Prospective Cohort Study
    Dongqing Jin, Ying Lu, Wei Wu, Fangyuan Jiang, Zihan Li, Liying Xu, Rongqi Zhang, Xue Li, Dong Chen
    Nutrients.2023; 15(22): 4801.     CrossRef
  • Male- and female-specific reproductive risk factors across the lifespan for dementia or cognitive decline: a systematic review and meta-analysis
    Shuang-Ling Han, De-Chun Liu, Chen-Chen Tan, Lan Tan, Wei Xu
    BMC Medicine.2023;[Epub]     CrossRef
  • Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis
    Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park
    Epidemiology and Health.2023; 45: e2023092.     CrossRef
  • ‘Pretty in Pink’ and ‘Girl Power’: An analysis of the targeting and representation of women in alcohol brand marketing on Facebook and Instagram
    A.M. Atkinson, B.R. Meadows, C. Emslie, A. Lyons, H.R. Sumnall
    International Journal of Drug Policy.2022; 101: 103547.     CrossRef
  • Very-light alcohol consumption suppresses breast tumor progression in a mouse model
    Xiuxiu Wang, Min Jia, Yifei Mao, Zhenzhen Jia, Huilin Liu, Guiwen Yang, Shuo Wang, Baoguo Sun, Hongyan Zhang
    Food & Function.2022; 13(6): 3391.     CrossRef
  • Global, regional, and national cancer deaths and disability‐adjusted life‐years (DALYs) attributable to alcohol consumption in 204 countries and territories, 1990‐2019
    Saeid Safiri, Seyed Aria Nejadghaderi, Nahid Karamzad, Kristin Carson‐Chahhoud, Nicola Luigi Bragazzi, Mark J. M. Sullman, Amir Almasi‐Hashiani, Mohammad Ali Mansournia, Gary S. Collins, Jay S. Kaufman, Ali‐Asghar Kolahi
    Cancer.2022; 128(9): 1840.     CrossRef
  • Adherence to the Vegetable-Fruit-Soy Dietary Pattern, a Reference From Mediterranean Diet, Protects Against Postmenopausal Breast Cancer Among Chinese Women
    Shang Cao, Linchen Liu, Qianrang Zhu, Zheng Zhu, Jinyi Zhou, Pingmin Wei, Ming Wu
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • The effects of modest drinking on life expectancy and mortality risks: a population-based cohort study
    Yen-Tze Liu, June Han Lee, Min Kuang Tsai, James Cheng-Chung Wei, Chi-Pang Wen
    Scientific Reports.2022;[Epub]     CrossRef
  • Colon Cancer: From Epidemiology to Prevention
    Kyriaki Katsaounou, Elpiniki Nicolaou, Paris Vogazianos, Cameron Brown, Marios Stavrou, Savvas Teloni, Pantelis Hatzis, Agapios Agapiou, Elisavet Fragkou, Georgios Tsiaoussis, George Potamitis, Apostolos Zaravinos, Chrysafis Andreou, Athos Antoniades, Chr
    Metabolites.2022; 12(6): 499.     CrossRef
  • Associations Between Physical Activity and Alcohol Consumption in Rural Cancer Survivors
    Scherezade K. Mama, Natalia I. Heredia, Hannah Johnston, David E. Conroy
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • Epidemiology beyond its limits
    Lauren E. McCullough, Maret L. Maliniak, Avnika B. Amin, Julia M. Baker, Davit Baliashvili, Julie Barberio, Chloe M. Barrera, Carolyn A. Brown, Lindsay J. Collin, Alexa A. Freedman, David C. Gibbs, Maryam B. Haddad, Eric W. Hall, Sarah Hamid, Kristin R. V
    Science Advances.2022;[Epub]     CrossRef
  • Review on recent development of quinoline for anticancer activities
    Mohan Ilakiyalakshmi, Ayyakannu Arumugam Napoleon
    Arabian Journal of Chemistry.2022; 15(11): 104168.     CrossRef
  • Relationship Between Physical Activity Levels and Thyroid Cancer Risk: A Prospective Cohort Study in Korea
    Anh Quynh Bui, Madhawa Gunathilake, Jeonghee Lee, Eun Kyung Lee, Jeongseon Kim
    Thyroid.2022; 32(11): 1402.     CrossRef
  • Frequent low dose alcohol intake increases gastric cancer risk: the Health Examinees-Gem (HEXA-G) study
    Hwi-Won Lee, Dan Huang, Woo-Kyoung Shin, Katherine de la Torre, Minkyo Song, Aesun Shin, Jong-Koo Lee, Daehee Kang
    Cancer Biology & Medicine.2022; 19(8): 1224.     CrossRef
  • Bewertung des Rotweinkonsums im Rahmen der mediterranen Ernährung – Eine systematische Literaturanalyse
    Benjamin Seethaler, Mirjam Fuchs, Julia Schumacher, Maryam Basrai, Marion Kiechle, Stephan C. Bischoff
    Aktuelle Ernährungsmedizin.2022; 47(05): 368.     CrossRef
  • What is behind the lifestyle risk factors for head and neck cancer?
    Anem Iftikhar, Mohammad Islam, Simon Shepherd, Sarah Jones, Ian Ellis
    Frontiers in Psychology.2022;[Epub]     CrossRef
  • Association of alcohol use with memory decline in middle-aged and older Chinese: a longitudinal cohort study
    Yu Meng Tian, Wei Sen Zhang, Chao Qiang Jiang, Feng Zhu, Ya Li Jin, Tong Zhu, Kar Keung Cheng, Lin Xu
    BMC Psychiatry.2022;[Epub]     CrossRef
  • Impact of Physical Activity on the Characteristics and Metabolic Consequences of Alcohol Consumption: A Cross-Sectional Population-Based Study
    Onni Niemelä, Aini Bloigu, Risto Bloigu, Anni S. Halkola, Markus Niemelä, Mauri Aalto, Tiina Laatikainen
    International Journal of Environmental Research and Public Health.2022; 19(22): 15048.     CrossRef
  • Current Developments in European Alcohol Policy: An Analysis of Possible Impacts on the German Wine Industry
    Frederik Nikolai Schulz, Barbara Richter, Jon H. Hanf
    Beverages.2022; 8(4): 75.     CrossRef
  • Polymorphisms in IL-17A Gene and Susceptibility of Colorectal Cancer in Bangladeshi Population: A Case-Control Analysis
    Md. Robiul Islam, Md. Abdul Aziz, Mohammad Shahriar, Mohammad Safiqul Islam
    Cancer Control.2022;[Epub]     CrossRef
  • Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population‐based cohort studies and two‐sample Mendelian randomization analyses
    Jue‐Sheng Ong, Eske M. Derks, Mikael Eriksson, Jiyuan An, Liang‐Dar Hwang, Douglas F. Easton, Paul P. Pharoah, Andrew Berchuck, Linda E. Kelemen, Keitaro Matsuo, Georgia Chenevix‐Trench, Per Hall, Stig E. Bojesen, Penelope M. Webb, Stuart MacGregor
    International Journal of Cancer.2021; 148(6): 1338.     CrossRef
  • Estimation of cancers caused by light to moderate alcohol consumption in the European Union
    Pol Rovira, Jürgen Rehm
    European Journal of Public Health.2021; 31(3): 591.     CrossRef
  • LncRNA PRNCR1 rs1456315 and CCAT2 rs6983267 Polymorphisms on 8q24 Associated with Lung Cancer
    Wei-Ling Yu, Jin-Jian Yao, Zong-Zhou Xie, Yan-Jing Huang, Sha Xiao
    International Journal of General Medicine.2021; Volume 14: 255.     CrossRef
  • Time trends of colorectal cancer incidence and associated lifestyle factors in South Korea
    Hayeong Khil, Sung Min Kim, SungEun Hong, Hyeon Min Gil, Eugene Cheon, Dong Hoon Lee, Young Ae Kim, NaNa Keum
    Scientific Reports.2021;[Epub]     CrossRef
  • Alcohol Consumption, HDL-Cholesterol and Incidence of Colon and Rectal Cancer: A Prospective Cohort Study Including 250,010 Participants
    Aage Tverdal, Gudrun Høiseth, Per Magnus, Øyvind Næss, Randi Selmer, Gun Peggy Knudsen, Jørg Mørland
    Alcohol and Alcoholism.2021; 56(6): 718.     CrossRef
  • Low-level alcohol consumption and cancer mortality
    Hyeonyoung Ko, Yoosoo Chang, Han-Na Kim, Jae-Heon Kang, Hocheol Shin, Eunju Sung, Seungho Ryu
    Scientific Reports.2021;[Epub]     CrossRef
  • Factors Associated with Women’s Unwillingness to Decrease Alcohol Intake to Decrease Breast Cancer Risk
    Jenna Matin, Rachel McFarland Lucia, Krustina Lal, Alyssa Columbus, Deborah Goodman, Kathryn Larsen, Argyrios Ziogas, Hannah Lui Park
    Journal of Primary Care & Community Health.2021;[Epub]     CrossRef
  • Past 6-Year Trends in Current Alcohol Use among Cyberbullied Adolescents
    George E. Higgins, Jason Nicholson, Catherine D. Marcum
    Substance Use & Misuse.2021; 56(6): 831.     CrossRef
  • Meme Kanserinden Korunmada ve Meme Kanseri Tedavisinde Akdeniz Diyetinin Etkisi
    Burcu DENİZ GÜNEŞ, Nilüfer ACAR TEK
    Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi.2021; 5(2): 442.     CrossRef
  • Global colorectal cancer burden in 2020 and projections to 2040
    Yue Xi, Pengfei Xu
    Translational Oncology.2021; 14(10): 101174.     CrossRef
  • Alcohol abstinence and mortality in a general population sample of adults in Germany: A cohort study
    Ulrich John, Hans-Juergen Rumpf, Monika Hanke, Christian Meyer, Charlotte Hanlon
    PLOS Medicine.2021; 18(11): e1003819.     CrossRef
  • Alcohol Use and Cancer in the European Union
    Jürgen Rehm, Kevin D. Shield
    European Addiction Research.2021; 27(1): 1.     CrossRef
  • Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes
    Firas Baidoun, Kholoud Elshiwy, Yasmine Elkeraie, Zahi Merjaneh, George Khoudari, Muhammad Talal Sarmini, Mohamed Gad, Muneer Al-Husseini, Anas Saad
    Current Drug Targets.2021; 22(9): 998.     CrossRef
  • Improving Knowledge that Alcohol Can Cause Cancer is Associated with Consumer Support for Alcohol Policies: Findings from a Real-World Alcohol Labelling Study
    Ashini Weerasinghe, Nour Schoueri-Mychasiw, Kate Vallance, Tim Stockwell, David Hammond, Jonathan McGavock, Thomas K. Greenfield, Catherine Paradis, Erin Hobin
    International Journal of Environmental Research and Public Health.2020; 17(2): 398.     CrossRef
  • Alcohol Consumption by Beverage Type and Risk of Breast Cancer: A Dose-Response Meta-Analysis of Prospective Cohort Studies
    Qiuyu Sun, Weihong Xie, Yanli Wang, Feifei Chong, Mengmeng Song, Tiandong Li, Linping Xu, Chunhua Song
    Alcohol and Alcoholism.2020; 55(3): 246.     CrossRef
  • The Burden and Trends of Breast Cancer From 1990 to 2017 at the Global, Regional, and National Levels: Results From the Global Burden of Disease Study 2017
    Peng Ji, Yue Gong, Ming-Liang Jin, Xin Hu, Gen-Hong Di, Zhi-Ming Shao
    Frontiers in Oncology.2020;[Epub]     CrossRef
  • General and particular issues of etiopathogenesis of peptic ulcer and gastric cancer: current status of the problem
    A. M. Osadchuk, I. L. Davydkin, T. A. Gricenko, M. A. Osadchuk
    Terapevticheskii arkhiv.2020; 92(2): 97.     CrossRef
  • Risk Factors of Cardiovascular Disease according to Alcohol Behavioral Change after Cancer Diagnosis
    Eun Mi Bae, In Young Cho, Ji-Hye Jun, Kiheon Lee, Ju Young Kim, Woo Kyung Bae, Hyejin Lee, Jong Soo Han, Se Young Jung, Kee Hyuck Lee, Sarah Kim, Hye Yeon Koo, Sang Jin Cho, Houbuem Lee, Chuelmin Paek
    Korean Journal of Family Medicine.2020; 41(4): 222.     CrossRef
  • Joint effect of tobacco, alcohol, and oral HPV infection on head and neck cancer risk in the French West Indies
    Aviane Auguste, Jacqueline Deloumeaux, Clarisse Joachim, Stanie Gaete, Leah Michineau, Cécile Herrmann‐Storck, Suzy Duflo, Danièle Luce
    Cancer Medicine.2020; 9(18): 6854.     CrossRef
  • Impacts of Habitual Diets Intake on Gut Microbial Counts in Healthy Japanese Adults
    Takuya Sugimoto, Tatsuichiro Shima, Ryuta Amamoto, Chiaki Kaga, Yukiko Kado, Osamu Watanabe, Junko Shiinoki, Kaoru Iwazaki, Hiroko Shigemura, Hirokazu Tsuji, Satoshi Matsumoto
    Nutrients.2020; 12(8): 2414.     CrossRef
  • Alcohol Consumption in Non-Alcoholic Fatty Liver Disease: Safety and Disease Overlap
    Sheela S. Reddy
    Current Hepatology Reports.2020; 19(4): 382.     CrossRef
  • Qualitative Study of Compliance with Nutritional Management in Colorectal Cancer Patient Undergoing Chemotherapy
    Heejung Park, Hyonson Kil, Wookyoun Cho
    Korean Journal of Community Nutrition.2020; 25(4): 303.     CrossRef
  • Heterogenous Effect of Risk Factors on Breast Cancer across the Breast Density Categories in a Korean Screening Population
    Boyoung Park, Se-Eun Lim, HyoJin Ahn, Junghyun Yoon, Yun Su Choi
    Cancers.2020; 12(6): 1391.     CrossRef
  • The effect of moderate alcohol drinking in nonalcoholic fatty liver disease
    Jong Hwa Choi, Won Sohn, Yong Kyun Cho
    Clinical and Molecular Hepatology.2020; 26(4): 662.     CrossRef
  • Report on Recently (2017–20) Designed Quinoline‐Based Human Cancer Cell Growth Inhibitors
    Atukuri Dorababu
    ChemistrySelect.2020; 5(44): 13902.     CrossRef
  • Validating Breast Cancer Risk Prediction Models in the Korean Cancer Prevention Study-II Biobank
    Yon Ho Jee, Chi Gao, Jihye Kim, Seho Park, Sun Ha Jee, Peter Kraft
    Cancer Epidemiology, Biomarkers & Prevention.2020; 29(6): 1271.     CrossRef
  • Light Alcohol Drinking and the Risk of Cancer Development: A Controversial Relationship
    Giuseppe G. Caprio, Desiree Picascia, Marcello Dallio, Pietro P. Vitiello, Emilio F. Giunta, Vincenzo De Falco, Ludovico Abenavoli, Anna C. Procopio, Vincenzo Famiglietti, Erika Martinelli, Antonietta G. Gravina, Alessandro Federico, Fortunato Ciardiello,
    Reviews on Recent Clinical Trials.2020; 15(3): 164.     CrossRef
  • Laboratory test based assessment of WHO alcohol risk drinking levels
    Onni Niemelä, Ulla Nivukoski, Aini Bloigu, Risto Bloigu, Mauri Aalto, Tiina Laatikainen
    Scandinavian Journal of Clinical and Laboratory Investigation.2019; 79(1-2): 58.     CrossRef
  • Wein und Krebs – was zeigt die epidemiologie?
    N. Worm, Jean-Marie Aurand
    BIO Web of Conferences.2019; 12: 04002.     CrossRef
  • Association of Periodontitis with Oral Cancer: A Case-Control Study
    Y.J. Shin, H.W. Choung, J.H. Lee, I.C. Rhyu, H.D. Kim
    Journal of Dental Research.2019; 98(5): 526.     CrossRef
  • Does Alcohol Use Affect Cancer Risk?
    Jürgen Rehm, Isabelle Soerjomataram, Carina Ferreira-Borges, Kevin D. Shield
    Current Nutrition Reports.2019; 8(3): 222.     CrossRef
  • Dietary index scores and invasive breast cancer risk among women with a family history of breast cancer
    Joshua Petimar, Yong-Moon Mark Park, Stephanie A Smith-Warner, Teresa T Fung, Dale P Sandler
    The American Journal of Clinical Nutrition.2019; 109(5): 1393.     CrossRef
  • Impacts of unfavourable lifestyle factors on biomarkers of liver function, inflammation and lipid status
    Ulla Nivukoski, Markus Niemelä, Aini Bloigu, Risto Bloigu, Mauri Aalto, Tiina Laatikainen, Onni Niemelä, Pedro Tauler
    PLOS ONE.2019; 14(6): e0218463.     CrossRef
  • Dietary Intake of Omega-3 fatty acids and Endocrine-related Gynecological Cancer: A Meta-Analysis of Observational Studies
    Tung Hoang, Seung-Kwon Myung, Thu Thi Pham
    Cancer Research and Treatment.2019; 51(3): 1022.     CrossRef
  • Colorectal cancer epidemiology in Korea
    Aesun Shin, Doeun Jang, Sunho Choe, Young-Joo Won, Kyu-Won Jung, Ji Won Park, Seung-Yong Jeong
    Journal of the Korean Medical Association.2019; 62(8): 407.     CrossRef
  • Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
    NaNa Keum, Edward Giovannucci
    Nature Reviews Gastroenterology & Hepatology.2019; 16(12): 713.     CrossRef
  • Alcohol Exposure Impacts the Composition of HeLa-Derived Extracellular Vesicles
    Leandra B. Jones, Sanjay Kumar, Aliyah J. Curry, Jayde S. Price, Alexandre Krendelchtchikov, Brennetta J. Crenshaw, Courtnee’ R. Bell, Sparkle D. Williams, Tambre A. Tolliver, Sabita N. Saldanha, Brian Sims, Qiana L. Matthews
    Biomedicines.2019; 7(4): 78.     CrossRef
  • Joint tobacco smoking and alcohol intake exacerbates cancer risk in women– the Danish nurse cohort
    Jette Heberg, Mette Kildevæld Simonsen, Anne Kjaergaard Danielsen, Tobias Wirenfeldt Klausen, Vibeke Zoffmann, Thordis Thomsen
    European Journal of Oncology Nursing.2019; 43: 101675.     CrossRef
  • Wie hoch ist das Krebs-Risiko bei moderate Weinkonsum im Rahmen einer mediterranen Ernährung?
    N. Worma, P. Roca
    BIO Web of Conferences.2019; 15: 04003.     CrossRef
  • From scientific evidence to media and policy: Wine – part of a balanced diet or a health risk?
    U. Fradera, C. Stein-Hammer, P. Roca
    BIO Web of Conferences.2019; 15: 04004.     CrossRef
  • The individual and combined effects of alcohol consumption and cigarette smoking on site-specific cancer risk in a prospective cohort of 26,607 adults: results from Alberta’s Tomorrow Project
    Benjamin Viner, Amanda M. Barberio, Tiffany R. Haig, Christine M. Friedenreich, Darren R. Brenner
    Cancer Causes & Control.2019; 30(12): 1313.     CrossRef
  • STUDY OF KNOWN RISK FACTORS IN BREAST CANCER PATIENTS IN THE REGIONAL POPULATION
    Ashok Kumar, Abhilash Bipin Kumar Tirkey, Sumitoj Singh, Rajiv Devgan
    Journal of Evolution of Medical and Dental Sciences.2019; 8(18): 1446.     CrossRef
  • High-Risk Drinking in the Elderly
    Seung-Won Oh
    Korean Journal of Family Medicine.2018; 39(4): 209.     CrossRef
  • Epidemiology of Moderate Alcohol Consumption and Breast Cancer: Association or Causation?
    Samir Zakhari, Jan B. Hoek
    Cancers.2018; 10(10): 349.     CrossRef
  • Alcohol and Health
    Giovanni de Gaetano, Simona Costanzo
    Journal of the American College of Cardiology.2017; 70(8): 923.     CrossRef
  • 22,873 View
  • 819 Download
  • 104 Web of Science
  • 100 Crossref
Close layer
Epidemiology of Intracranial Metastases in Korea: A National Cohort Investigation
Tackeun Kim, Changhoon Song, Jung Ho Han, In-Ah Kim, Yu Jung Kim, Se Hyun Kim, Jee Hyun Kim, Chae-Yong Kim
Cancer Res Treat. 2018;50(1):164-174.   Published online March 21, 2017
DOI: https://doi.org/10.4143/crt.2017.072
AbstractAbstract PDFPubReaderePub
Purpose
To investigate the epidemiologic features of intracranial metastases (ICMET) in Korea, we performed a cohort study using the National Health Insurance Service–National Sample Cohort database, which comprised healthcare usage information of approximately 1 million Korean individuals over 12 years.
Materials and Methods
We enrolled 998,602 subjects, after excluding 18,218 subjects diagnosed with any cancer during the washout period (2002-2004). The observation period was 9 years (2005-2013; 8,725,438 person-years). The initial diagnosis date of ICMET and the primary cancer was recorded. The incidence was determined based on the number of incident cases and observation size, whereas survival was estimated using death statistics from the database.
Results
Through observation period, a total 776 subjects developed ICMET. The age-standardized incidence of ICMET was 8.2 per 100,000 person-years. The mean interval between the initial diagnosis date of the primary cancer and ICMET was 13.1 months. Patients with ICMET had shorter survival than those without ICMET (30.9 months vs. 81.4 months, p < 0.001). The ICMET incidence among the cancer patients was 5.0 per 1,000 personyears; it was highest in lung cancer cases, followed by breast and liver cancer cases. Moreover, ICMET from lung cancer was the most common metastasis type, followed by ICMET from liver and breast cancer.
Conclusion
The incidence of ICMET was 8.2 per 100,000 person-years among the Korean population and 5.0 per 1,000 person-years among cancer patients. Most of the ICMET cases arose from lung cancer. ICMET also critically influenced survival in cancer patients.

Citations

Citations to this article as recorded by  
  • TRP-2 / gp100 DNA vaccine and PD-1 checkpoint blockade combination for the treatment of intracranial tumors
    Joshua R. D. Pearson, Carles Puig-Saenz, Jubini E. Thomas, Lydia D. Hardowar, Murrium Ahmad, Louise C. Wainwright, Adam M. McVicar, Victoria A. Brentville, Chris J. Tinsley, A. Graham Pockley, Lindy G. Durrant, Stephanie E. B. McArdle
    Cancer Immunology, Immunotherapy.2024;[Epub]     CrossRef
  • Dural Metastasis in Breast Cancer: MRI-Based Morphological Subtypes and Their Clinical Implications
    Sung Jun Ahn, Bio Joo, Mina Park, Hun Ho Park, Sang Hyun Suh, Sung Gwe Ahn, Jihwan Yoo
    Cancer Research and Treatment.2024; 56(4): 1105.     CrossRef
  • Treatment Outcome of the Brain Metastases in Peri-Rolandic Area: Comparison Between Surgery and Stereotactic Radiosurgery
    Jun Hyeok Jung, Kawngwoo Park, Eun Young Kim, Chan-Jong Yoo, Gi-Taek Yee, Woo-Kyung Kim, Dong-Won Shin
    Brain Tumor Research and Treatment.2023; 11(4): 246.     CrossRef
  • Mutational profiles of primary pulmonary adenocarcinoma and paired brain metastases disclose the importance of KRAS mutations
    Erik Vassella, Elham Kashani, Philipp Zens, Alexandra Kündig, Christian Fung, Amina Scherz, Evelyn Herrmann, Ekin Ermis, Ralph A. Schmid, Sabina Berezowska
    European Journal of Cancer.2021; 159: 227.     CrossRef
  • Verification of Low Risk for Perihippocampal Recurrence in Patients with Brain Metastases Who Received Whole-Brain Radiotherapy with Hippocampal Avoidance
    Youngkyong Kim, Sung Hwan Kim, Jong Hoon Lee, Dae Gyu Kang
    Cancer Research and Treatment.2019; 51(2): 568.     CrossRef
  • Non–coplanar whole brain radiotherapy is an effective modality for parotid sparing
    Jaehyeon Park, Jae Won Park, Ji Woon Yea
    Yeungnam University Journal of Medicine.2019; 36(1): 36.     CrossRef
  • Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
    Jaehyeon Park, Ji Woon Yea
    Radiation Oncology Journal.2019; 37(1): 22.     CrossRef
  • 9,056 View
  • 238 Download
  • 5 Web of Science
  • 7 Crossref
Close layer
The Clinical Significance of Occult Gastrointestinal Primary Tumours in Metastatic Cancer: A Population Retrospective Cohort Study
Malek B. Hannouf, Eric Winquist, Salaheddin M. Mahmud, Muriel Brackstone, Sisira Sarma, George Rodrigues, Peter K. Rogan, Jeffrey S. Hoch, Gregory S. Zaric
Cancer Res Treat. 2018;50(1):183-194.   Published online March 21, 2017
DOI: https://doi.org/10.4143/crt.2016.532
AbstractAbstract PDFPubReaderePub
Purpose
The purpose of this study was to estimate the incidence of occult gastrointestinal (GI) primary tumours in patients with metastatic cancer of uncertain primary origin and evaluate their influence on treatments and overall survival (OS).
Materials and Methods
We used population heath data from Manitoba, Canada to identify all patients initially diagnosed with metastatic cancer between 2002 and 2011. We defined patients to have “occult” primary tumour if the primary was found at least 6 months after initial diagnosis. Otherwise, we considered primary tumours as “obvious.” We used propensity-score methods to match each patient with occult GI tumour to four patients with obvious GI tumour on all known clinicopathologic features. We compared treatments and 2-year survival data between the two patient groups and assessed treatment effect on OS using Cox regression adjustment.
Results
Eighty-three patients had occult GI primary tumours, accounting for 17.6% of men and 14% of women with metastatic cancer of uncertain primary. A 1:4 matching created a matched group of 332 patients with obvious GI primary tumour. Occult cases compared to the matched group were less likely to receive surgical interventions and targeted biological therapy, and more likely to receive cytotoxic empiric chemotherapeutic agents. Having an occult GI tumour was associated with reduced OS and appeared to be a nonsignificant independent predictor of OS when adjusting for treatment differences.
Conclusion
GI tumours are the most common occult primary tumours in men and the second most common in women. Patients with occult GI primary tumours are potentially being undertreated with available GI site-specific and targeted therapies.

Citations

Citations to this article as recorded by  
  • Relationship between metastasis and second primary cancers in women with breast cancer
    Chaofan Li, Mengjie Liu, Jia Li, Xixi Zhao, Yusheng Wang, Xi Chen, Weiwei Wang, Shiyu Sun, Cong Feng, Yifan Cai, Fei Wu, Chong Du, Yinbin Zhang, Shuqun Zhang, Jingkun Qu
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • The Potential Clinical and Economic Value of Primary Tumour Identification in Metastatic Cancer of Unknown Primary Tumour: A Population-Based Retrospective Matched Cohort Study
    Malek B. Hannouf, Eric Winquist, Salaheddin M. Mahmud, Muriel Brackstone, Sisira Sarma, George Rodrigues, Peter K. Rogan, Jeffrey S. Hoch, Gregory S. Zaric
    PharmacoEconomics - Open.2018; 2(3): 255.     CrossRef
  • 9,120 View
  • 140 Download
  • 2 Web of Science
  • 2 Crossref
Close layer
Trends and Age-Period-Cohort Effects on the Incidence and Mortality Rate of Cervical Cancer in Korea
Eun-Kyeong Moon, Chang-Mo Oh, Young-Joo Won, Jong-Keun Lee, Kyu-Won Jung, Hyunsoon Cho, Jae Kwan Jun, Myong Cheol Lim, Moran Ki
Cancer Res Treat. 2017;49(2):526-533.   Published online September 1, 2016
DOI: https://doi.org/10.4143/crt.2016.316
AbstractAbstract PDFPubReaderePub
Purpose
This study was conducted to describe the trends and age-period-cohort effects on the incidence and mortality rate of cervical cancer in Korea.
Materials and Methods
The incidence and mortality rate of cervical cancer among ≥ 20-year-old women from 1993 to 2012 were obtained from the Korea Central Cancer Registry and the Korean Statistical Information Service. Age-standardized rates were calculated and Joinpoint regression was used to evaluate the trends in the incidence and mortality rate. Age-period-cohort analysis was performed to investigate the independent effects of age, period and cohort.
Results
The incidence of cervical cancer decreased from 32.8 per 100,000 in 1993 to 15.9 per 100,000 in 2012 (annual percent change [APC], –3.9%; 95% confidence interval [CI], –4.2% to –3.6%). The mortality rate decreased from 5.2 per 100,000 in 1993 to 2.1 per 100,000 in 2012 (APC, –4.8%; 95% CI, –5.1% to –4.4%); however, the incidence and mortality rates among young women (< 30 years old) increased. An age-period-cohort model of the incidence and mortality rate showed decreasing period effects between 1993 and 2008 and decreasing cohort effects between 1928 and 1973, while birth cohorts after 1973 exhibited slight increases in the incidence and mortality rate of cervical cancer.
Conclusion
Recent decreases in the incidence and mortality rate of cervical cancer were due to decreases in the period and cohort effects, which reflect the implementation of a cancer screening program and changes in lifestyle. However, our findings also highlighted an increase in cohort effects on the incidence and mortality rate among young women born after 1973.

Citations

Citations to this article as recorded by  
  • Trends in gynecological cancer incidence, mortality, and survival among elderly women: A SEER study
    Subhadra Priyadarshini, Prafulla Kumar Swain, Khushi Agarwal, Diptismita Jena, Sourav Padhee
    AGING MEDICINE.2024; 7(2): 179.     CrossRef
  • Determination of ovarian transposition through prediction of postoperative adjuvant therapy in young patients with early stage cervical cancer undergoing surgery: a Korean multicenter retrospective study (KGOG 1042)
    Woo Yeon Hwang, Chel Hun Choi, Kidong Kim, Moon-Hong Kim, Myong Cheol Lim, Banghyun Lee, Myounghwan Kim, Yun Hwan Kim, Seok Ju Seong, Jong-Min Lee
    Obstetrics & Gynecology Science.2024; 67(3): 296.     CrossRef
  • Global, regional, and national trends in mesothelioma burden from 1990 to 2019 and the predictions for the next two decades
    Wenmin Zhu, Jialin Liu, Yiling Li, Ziwei Shi, Sheng Wei
    SSM - Population Health.2023; 23: 101441.     CrossRef
  • Changes in cervical dysplasia, carcinoma in situ, and cervical cancer after expanding the National Cancer Screening Program to younger women in Korea
    Woorim Kim, Sungyoun Chun, Sang Ah Lee
    International Journal for Quality in Health Care.2023;[Epub]     CrossRef
  • Secular trend in disease burden of leukemia and its subtypes in China from 1990 to 2019 and its projection in 25 years
    Dongdong Niu, Yumei Zhao, Jia Wang, Enlin Ye, Jiasheng Huang, Jie Liu, Xueying Huang, Suru Yue, Xuefei Hou, Jiayuan Wu
    Annals of Hematology.2023; 102(9): 2375.     CrossRef
  • Gigantol inhibits proliferation and enhanced oxidative stress‐mediated apoptosis through modulating of Wnt/β‐catenin signaling pathway in HeLa cells
    Huanan Kang, Yiming Sun, Xijiao Hu, Li Liu
    Journal of Biochemical and Molecular Toxicology.2022;[Epub]     CrossRef
  • Antiproliferative and apoptotic potential of Glycyrrhizin against HPV16+ Caski cervical cancer cells: A plausible association with downreguation of HPV E6 and E7 oncogenes and Notch signaling pathway
    Afza Ahmad, Rohit Kumar Tiwari, Prakriti Mishra, Ali G. Alkhathami, Tahani M. Almeleebia, Mohammad Y. Alshahrani, Irfan Ahmad, Rawan Amer Asiri, Noura M. Alabdullah, Mohamed Hussien, Mohd Saeed, Irfan Ahmad Ansari
    Saudi Journal of Biological Sciences.2022; 29(5): 3264.     CrossRef
  • Trends in cervical cancer screening rates among Korean women: results of the Korean National Cancer Screening Survey, 2005–2020
    Hye Young Shin, Yun Yeong Lee, Soo Yeon Song, Bomi Park, Mina Suh, Kui Son Choi, Jae Kwan Jun
    Journal of Gynecologic Oncology.2022;[Epub]     CrossRef
  • Disparities in the increases of cervical cancer incidence rates: observations from a city-wide population-based study
    Ke Li, Huan Xu, Suixiang Wang, Pengzhe Qin, Boheng Liang
    BMC Cancer.2022;[Epub]     CrossRef
  • Inequalities in Temporal Effects on Cervical Cancer Mortality in States in Different Geographic Regions of Brazil: An Ecological Study
    Karina Cardoso Meira, Carinne Magnago, Angelo Braga Mendonça, Stephane Fernanda Soares Duarte, Pedro Henrique Oliveira de Freitas, Juliano dos Santos, Dyego Leandro Bezerra de Souza, Taynãna César Simões
    International Journal of Environmental Research and Public Health.2022; 19(9): 5591.     CrossRef
  • Trends in Incidence Rates, Mortality Rates, and Age-Period-Cohort Effects of Cervical Cancer — China, 2003–2017
    Kexin Sun, Rongshou Zheng, Lin Lei, Siwei Zhang, Hongmei Zeng, Shaoming Wang, Li Li, Ru Chen, Bingfeng Han, Ji Peng, Wenqiang Wei, Jie He
    China CDC Weekly.2022; 4(48): 1070.     CrossRef
  • Population-Based Temporal Trends and Ethnic Disparity in Cervical Cancer Mortality in South Africa (1999–2018): A Join Point and Age–Period–Cohort Regression Analyses
    Gbenga Olorunfemi, Elena Libhaber, Oliver Ezechi, Eustasius Musenge
    Cancers.2022; 14(24): 6256.     CrossRef
  • Understanding of Cervical Screening Adoption among Female University Students Based on the Precaution Adoption Process Model and Health-Belief Model
    Hye Young Shin, Purum Kang, Soo Yeon Song, Jae Kwan Jun
    International Journal of Environmental Research and Public Health.2022; 20(1): 700.     CrossRef
  • The Effects of Age, Period, and Cohort on the Mortality of Cervical Cancer in Three High-Income Countries: Canada, Korea, and Italy
    Jinyao Wang, Zhiqiang Bai, Xudong Gao, Nianping Zhang, Zhenkun Wang, Zhongjie Shi
    BioMed Research International.2021; 2021: 1.     CrossRef
  • Metasequoia glyptostroboides potentiates anticancer effect against cervical cancer via intrinsic apoptosis pathway
    Hoomin Lee, Cheolwoo Oh, Suji Kim, Debasish Kumar Dey, Hyung Kyo Kim, Vivek K. Bajpai, Young-Kyu Han, Yun Suk Huh
    Scientific Reports.2021;[Epub]     CrossRef
  • The Trend of HIV/AIDS Incidence and Risks Associated with Age, Period, and Birth Cohort in Four Central African Countries
    Nodjimadji Tamlengar Martial, Sumaira Mubarik, Chuanhua Yu
    International Journal of Environmental Research and Public Health.2021; 18(5): 2564.     CrossRef
  • Trends in breast and cervical cancer in India under National Cancer Registry Programme: An Age-Period-Cohort analysis
    Krishnan Sathishkumar, Vinodh N, R.A. Badwe, S.V.S. Deo, N. Manoharan, Reeni Malik, NS Panse, C. Ramesh, Atul Shrivastava, R. Swaminathan, C.R. Vijay, Sandeep Narasimhan, Meesha Chaturvedi, Prashant Mathur
    Cancer Epidemiology.2021; 74: 101982.     CrossRef
  • Tendencias temporales del cáncer de cuello uterino invasivo en mujeres entre 20 y 39 años en Manizales, Colombia. 2003-2018
    María Del Pilar Arango Arango
    Revista Médica de Risaralda.2021;[Epub]     CrossRef
  • Analysis of the effects of the age-period-birth cohort on cervical cancer mortality in the Brazilian Northeast
    Karina Cardoso Meira, Glauber Weder dos Santos Silva, Juliano dos Santos, Raphael Mendonça Guimarães, Dyego Leandro Bezerra de Souza, Gilcilene Pretta Cani Ribeiro, Eder Samuel Oliveira Dantas, Jovanka Bittencourt Leite de Carvalho, Rafael Tavares Jomar,
    PLOS ONE.2020; 15(2): e0226258.     CrossRef
  • Age-Period-Cohort Analysis of HIV Mortality in China: Data from the Global Burden of Disease Study 2016
    Disi Gao, Zhiyong Zou, Wenjing Zhang, Tianqi Chen, Wenxin Cui, Yinghua Ma
    Scientific Reports.2020;[Epub]     CrossRef
  • Kallikrein 5 overexpression is associated with poor prognosis in uterine cervical cancer
    Jee Suk Chang, Nalee Kim, Ji-Ye Kim, Sung-Im Do, Yeona Cho, Hyun-Soo Kim, Yong Bae Kim
    Journal of Gynecologic Oncology.2020;[Epub]     CrossRef
  • Trends in cervical cancer mortality in Brazil in 5 years (2012-2016)
    Blenda Tallon, Denise Monteiro, Leila Soares, Nádia Rodrigues, Flavio Morgado
    Saúde em Debate.2020; 44(125): 362.     CrossRef
  • Tendências da mortalidade por câncer de colo no Brasil em 5 anos (2012-2016)
    Blenda Tallon, Denise Monteiro, Leila Soares, Nádia Rodrigues, Flavio Morgado
    Saúde em Debate.2020; 44(125): 362.     CrossRef
  • Cervical Cancer Screening and Human Papillomavirus Vaccination among Korean Sexual Minority Women by Sex of Their Sexual Partners
    Ssirai Kim, Sun-Young Lee, Smi Choi-Kwon
    International Journal of Environmental Research and Public Health.2020; 17(23): 8924.     CrossRef
  • Increasing risk of uterine cervical cancer among young Japanese women: Comparison of incidence trends in Japan, South Korea and Japanese‐Americans between 1985 and 2012
    Mai Utada, Pavel Chernyavskiy, Won Jin Lee, Silvia Franceschi, Catherine Sauvaget, Amy Berrington de Gonzalez, Diana R. Withrow
    International Journal of Cancer.2019; 144(9): 2144.     CrossRef
  • Ovarian transposition before radiotherapy in cervical cancer patients: functional outcome and the adequate dose constraint
    Lina Yin, Saiquan Lu, Jun Zhu, Weiling Zhang, Guihao Ke
    Radiation Oncology.2019;[Epub]     CrossRef
  • Prevalence of human papillomavirus-related diseases in the Republic of Korea: a cross-sectional study
    Jin-Kyoung Oh, Hwa Young Choi, Minji Han, Jae-Kwan Lee, Kyung-Jin Min, Moran Ki
    Sexually Transmitted Infections.2019; 95(4): 292.     CrossRef
  • Contributions and Limitations of National Cervical Cancer Screening Program in Korea: A Retrospective Observational Study
    Jung Hyun Lee, Hyeongsu Kim, Heejung Choi, Hyoseon Jeong, Young Ko, Seung-Hyuk Shim, Eunjoo Lee, Su Hyun Chae
    Asian Nursing Research.2018; 12(1): 9.     CrossRef
  • The Prognostic Impact of the Number of Metastatic Lymph Nodes and a New Prognostic Scoring System for Recurrence in Early-Stage Cervical Cancer with High Risk Factors: A Multicenter Cohort Study (KROG 15-04)
    Jeanny Kwon, Keun-Young Eom, Young Seok Kim, Won Park, Mison Chun, Jihae Lee, Yong Bae Kim, Won Sup Yoon, Jin Hee Kim, Jin Hwa Choi, Sei Kyung Chang, Bae Kwon Jeong, Seok Ho Lee, Jihye Cha
    Cancer Research and Treatment.2018; 50(3): 964.     CrossRef
  • Who Really Benefits from 3D-Based Planning of Brachytherapy for Cervical Cancer?
    In Bong Ha, Bae Kwon Jeong, Ki Mun Kang, Hojin Jeong, Yun Hee Lee, Hoon Sik Choi, Jong Hak Lee, Won Jun Choi, Jeong Kyu Shin, Jin Ho Song
    Journal of Korean Medical Science.2018;[Epub]     CrossRef
  • Induction of Apoptotic Cell Death on Human Cervix Cancer HeLa cells by Extract from Loranthus yadoriki
    Eun-Joo Kim, Chang-Won Kang, Nan-Hee Kim, Yong Bae Seo, Soo-Wan Nam, Gun-Do Kim
    Biotechnology and Bioprocess Engineering.2018; 23(2): 201.     CrossRef
  • Updates on Cancer Epidemiology in Korea, 2018
    Sun-Seog Kweon
    Chonnam Medical Journal.2018; 54(2): 90.     CrossRef
  • The economic burden of human papillomavirus infection-associated diseases in the Republic of Korea, 2002–2015
    Moran Ki, Hwa Young Choi, Minji Han, Jin-Kyoung Oh
    Vaccine.2018; 36(31): 4633.     CrossRef
  • How confident can we be in the current guidelines for exiting cervical screening?
    Patti E. Gravitt, Rebecca Landy, Mark Schiffman
    Preventive Medicine.2018; 114: 188.     CrossRef
  • Comparison of gynecologic cancer risk factors, incidence and mortality trends between South Korea and Israel, 1999–2013
    N Michaan, S Y Park, Y J Won, M C Lim
    Japanese Journal of Clinical Oncology.2018; 48(10): 884.     CrossRef
  • 14,579 View
  • 351 Download
  • 35 Web of Science
  • 35 Crossref
Close layer
Meta-Analysis
Alcohol Intake and Risk of Thyroid Cancer: A Meta-Analysis of Observational Studies
Seung-Hee Hong, Seung-Kwon Myung, Hyeon Suk Kim, The Korean Meta-Analysis (KORMA) Study Group
Cancer Res Treat. 2017;49(2):534-547.   Published online July 7, 2016
DOI: https://doi.org/10.4143/crt.2016.161
AbstractAbstract PDFPubReaderePub
Purpose
The purpose of this study was to assess whether alcohol intake is associated with the risk of thyroid cancer by a meta-analysis of observational studies.
Materials and Methods
We searched PubMed and EMBASE in June of 2015 to locate eligible studies. We included observational studies such as cross-sectional studies, case-control studies, and cohort studies reporting odd ratios (ORs) or relative risk (RRs) with 95% confidence intervals (CIs).
Results
We included 33 observational studies with two cross-sectional studies, 20 case-controls studies, and 11 cohort studies, which involved a total of 7,725 thyroid cancer patients and 3,113,679 participants without thyroid cancer in the final analysis. In the fixed-effect model meta-analysis of all 33 studies, we found that alcohol intake was consistently associated with a decreased risk of thyroid cancer (OR or RR, 0.74; 95% CI, 0.67 to 0.83; I2=38.6%). In the subgroup meta-analysis by type of study, alcohol intake also decreased the risk of thyroid cancer in both case-control studies (OR, 0.77; 95% CI, 0.65 to 0.92; I2=29.5%; n=20) and cohort studies (RR, 0.70; 95% CI, 0.60 to 0.82; I2=0%; n=11). Moreover, subgroup meta-analyses by type of thyroid cancer, gender, amount of alcohol consumed, and methodological quality of study showed that alcohol intake was significantly associated with a decreased risk of thyroid cancer.
Conclusion
The current meta-analysis of observational studies found that, unlike most of other types of cancer, alcohol intake decreased the risk of thyroid cancer.

Citations

Citations to this article as recorded by  
  • Prevalence of thyroid nodule and relationship with physiological and psychosocial factors among adults in Zhejiang Province, China: a baseline survey of a cohort study
    Xueqing Li, Zhijian Chen, Lizhi Wu, Pengchen Tu, Zhe Mo, Mingluan Xing
    BMC Public Health.2024;[Epub]     CrossRef
  • The influence of nutrition in nodular thyroid pathology: a systematic review
    Vanessa Neto, Catarina Leitão, Marta Estrela, Margarida Fardilha, Maria Teresa Herdeiro, Alexandra Nunes
    Critical Reviews in Food Science and Nutrition.2024; : 1.     CrossRef
  • Associations Between Obesity and Risk of Thyroid Cancer: A Meta-Analysis of Cohort Studies
    Urfa Khairatun Hisan, Seung-Kwon Myung, Giap Viet Nguyen
    Nutrition and Cancer.2024; : 1.     CrossRef
  • Alcohol consumption and its association with cancer, cardiovascular, liver and brain diseases: a systematic review of Mendelian randomization studies
    Naouras Bouajila, Cloé Domenighetti, Henri-Jean Aubin, Mickael Naassila
    Frontiers in Epidemiology.2024;[Epub]     CrossRef
  • Sweetened beverages are associated with a higher risk of differentiated thyroid cancer in the EPIC cohort: a dietary pattern approach
    Raul Zamora-Ros, Valerie Cayssials, Ramon Clèries, Maria Torrents, Graham Byrnes, Elisabete Weiderpass, Maria Sandström, Martin Almquist, Marie-Christine Boutron-Ruault, Anne Tjønneland, Cecilie Kyrø, Verena A. Katzke, Charlotte Le Cornet, Giovanna Masala
    European Journal of Nutrition.2023; 62(1): 105.     CrossRef
  • Molecular Testing Results for Indeterminate Thyroid Nodules and Social Habits
    Hui Zheng, John F. Whitney, Victoria Lai
    Journal of Surgical Research.2023; 284: 245.     CrossRef
  • Smoking and alcohol consumption with the risk of 11 common otolaryngological diseases: a bidirectional Mendelian randomization
    Xu Wang, Yuewei Bi, Guangping Liu, Wei Wang, Hualei Cui
    European Archives of Oto-Rhino-Laryngology.2023; 280(12): 5615.     CrossRef
  • Will metformin use lead to a decreased risk of thyroid cancer? A systematic review and meta-analyses
    Hailong Li, Yue Chen, Lei Hu, Wenzhi Yang, Zongshi Gao, Mengqing Liu, Hui Tao, Jie Li
    European Journal of Medical Research.2023;[Epub]     CrossRef
  • Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis
    Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park
    Epidemiology and Health.2023; 45: e2023092.     CrossRef
  • Adapted dietary inflammatory index and differentiated thyroid carcinoma risk in two French population-based case–control studies
    Lucie Lécuyer, Nasser Laouali, Mariem Hajji-Louati, Melanie Paquet, Vincent Souchard, Mojgan Karimi, Claire Schvartz, Anne-Valérie Guizard, Constance Xhaard, Carole Rubino, Yan Ren, Françoise Borson-Chazot, Elisabeth Adjadj, Emilie Cordina-Duverger, Flore
    European Journal of Nutrition.2022; 61(2): 1097.     CrossRef
  • Association between Thyroid Cancer and Breast Cancer: Two Longitudinal Follow-Up Studies Using a National Health Screening Cohort
    Young Ju Jin, Mi Jung Kwon, Ji Hee Kim, Joo-Hee Kim, Hyo Geun Choi
    Journal of Personalized Medicine.2022; 12(2): 133.     CrossRef
  • Smoking, Alcohol Consumption, and the Risk of Thyroid Cancer: A Population-Based Korean Cohort Study of 10 Million People
    Yohwan Yeo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Tae Hyuk Kim, Sohyun Chun, Su-Min Jeong, Yun-Mi Song
    Thyroid.2022; 32(4): 440.     CrossRef
  • Alcohol and Health Outcomes: An Umbrella Review of Meta-Analyses Base on Prospective Cohort Studies
    Lixian Zhong, Weiwei Chen, Tonghua Wang, Qiuting Zeng, Leizhen Lai, Junlong Lai, Junqin Lin, Shaohui Tang
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Inflammatory potential of the diet and association with risk of differentiated thyroid cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
    Lucie Lécuyer, Nasser Laouali, Laure Dossus, Nitin Shivappa, James R. Hébert, Antonio Agudo, Anne Tjonneland, Jytte Halkjaer, Kim Overvad, Verena A. Katzke, Charlotte Le Cornet, Matthias B. Schulze, Franziska Jannasch, Domenico Palli, Claudia Agnoli, Rosa
    European Journal of Nutrition.2022; 61(7): 3625.     CrossRef
  • Are “Bad Habits” Good? The Relationships Between Smoking, Alcohol Use, and Thyroid Cancer
    Alex Tessnow
    Clinical Thyroidology.2022; 34(7): 309.     CrossRef
  • Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study
    Fjorida Llaha, Valerie Cayssials, Marta Farràs, Antonio Agudo, Maria Sandström, Anne Kirstine Eriksen, Anne Tjønneland, Marie-Christine Boutron-Ruault, Nasser Laouali, Thérèse Truong, Charlotte Le Cornet, Verena Katzke, Matthias Schulze, Domenico Palli, V
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Multiethnic genome‐wide association study of differentiated thyroid cancer in the EPITHYR consortium
    Thérèse Truong, Fabienne Lesueur, Pierre‐Emmanuel Sugier, Julie Guibon, Constance Xhaard, Mojgan Karimi, Om Kulkarni, Elise A. Lucotte, Delphine Bacq‐Daian, Anne Boland‐Auge, Claire Mulot, Pierre Laurent‐Puig, Claire Schvartz, Anne‐Valérie Guizard, Yan Re
    International Journal of Cancer.2021; 148(12): 2935.     CrossRef
  • Association of Polygenetic Risk Scores Related to Cell Differentiation and Inflammation with Thyroid Cancer Risk and Genetic Interaction with Dietary Intake
    Sang Shin Song, ShaoKai Huang, Sunmin Park
    Cancers.2021; 13(7): 1510.     CrossRef
  • Incidence and mortality from thyroid cancer in Latin America
    Fábia Cheyenne Gomes de Morais Fernandes, Dyego Leandro Bezerra de Souza, Maria Paula Curado, Talita Araujo de Souza, Arthur de Almeida Medeiros, Isabelle Ribeiro Barbosa
    Tropical Medicine & International Health.2021; 26(7): 800.     CrossRef
  • Trends in Childhood Thyroid Cancer incidence in Korea and Its Potential Risk Factors
    Jun Park, Hyunju Park, Tae Hyuk Kim, Sun Wook Kim, Hye Won Jang, Jae Hoon Chung
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • Changes in Smoking, Alcohol Consumption, and the Risk of Thyroid Cancer: A Population-Based Korean Cohort Study
    Yohwan Yeo, Kyungdo Han, Dong-Wook Shin, Dahye Kim, Su-Min Jeong, Sohyun Chun, In-Young Choi, Keun-Hye Jeon, Tae-Hyuk Kim
    Cancers.2021; 13(10): 2343.     CrossRef
  • Der Tumormarker Thyreoglobulin
    K. Passek, N. Zulauf, M. H. Bendels, D. Quarcoo, G. M. Oremek
    Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie.2020; 70(1): 40.     CrossRef
  • Withdrawn: Smoking, alcohol consumption, and the risk of thyroid cancer: a population-based Korean cohort study of 10 million people
    Yohwan Yeo, Dong Wook Shin, Kyung-Do Han, Dahye Kim, Tae Hyuk Kim, Sohyun Chun, Sumin Jeong, Yun-Mi Song
    Thyroid.2020;[Epub]     CrossRef
  • Association between Family Histories of Thyroid Cancer and Thyroid Cancer Incidence: A Cross-Sectional Study Using the Korean Genome and Epidemiology Study Data
    Soo-Hwan Byun, Chanyang Min, Hyo-Geun Choi, Seok-Jin Hong
    Genes.2020; 11(9): 1039.     CrossRef
  • A national database analysis for factors associated with thyroid cancer occurrence
    Joon-Hyop Lee, Sora Youn, Sohee Jung, Kwangsoo Kim, Young Jun Chai, Yoo Seung Chung, Won Seo Park, Kyu Eun Lee, Ka Hee Yi
    Scientific Reports.2020;[Epub]     CrossRef
  • Obesity is positively related and tobacco smoking and alcohol consumption are negatively related to an increased risk of thyroid cancer
    Soo-Youn An, So Young Kim, Dong Jun Oh, Chanyang Min, Songyoung Sim, Hyo Geun Choi
    Scientific Reports.2020;[Epub]     CrossRef
  • Human milk as a protective factor for bronchopulmonary dysplasia: a systematic review and meta-analysis
    Jinglan Huang, Li Zhang, Jun Tang, Jing Shi, Yi Qu, Tao Xiong, Dezhi Mu
    Archives of Disease in Childhood - Fetal and Neonatal Edition.2019; 104(2): F128.     CrossRef
  • Leukocyte Mitochondrial DNA Copy Number and Risk of Thyroid Cancer: A Two-Stage Case-Control Study
    Jian Zheng, Ning-hua Cui, Shuai Zhang, Xue-bin Wang, Liang Ming
    Frontiers in Endocrinology.2019;[Epub]     CrossRef
  • Contemporary Debates in Adult Papillary Thyroid Cancer Management
    Donald S A McLeod, Ling Zhang, Cosimo Durante, David S Cooper
    Endocrine Reviews.2019; 40(6): 1481.     CrossRef
  • Low expression of ryanodine receptor 2 is associated with poor prognosis in thyroid carcinoma
    Nizhen Xu, Deguang Zhang, Jian Chen, Gaofei He, Li Gao
    Oncology Letters.2019;[Epub]     CrossRef
  • A Linkage Between Thyroid and Breast Cancer: A Common Etiology?
    Eric L. Bolf, Brian L. Sprague, Frances E. Carr
    Cancer Epidemiology, Biomarkers & Prevention.2019; 28(4): 643.     CrossRef
  • Interaction between alcohol consumption and methylenetetrahydrofolate reductase polymorphisms in thyroid cancer risk: National Cancer Center cohort in Korea
    Sarah Yang, Jeonghee Lee, Yoon Park, Eun Kyung Lee, Yul Hwangbo, Junsun Ryu, Joohon Sung, Jeongseon Kim
    Scientific Reports.2018;[Epub]     CrossRef
  • Alcohol consumption and risk of hematological malignancies: A meta‐analysis of prospective studies
    Theodora Psaltopoulou, Theodoros N. Sergentanis, Ioannis Ntanasis‐Stathopoulos, Ioannis‐Georgios Tzanninis, Diamantis I. Tsilimigras, Meletios A. Dimopoulos
    International Journal of Cancer.2018; 143(3): 486.     CrossRef
  • Light Alcohol Drinking and Risk of Cancer: A Meta-Analysis of Cohort Studies
    Yoon-Jung Choi, Seung-Kwon Myung, Ji-Ho Lee
    Cancer Research and Treatment.2018; 50(2): 474.     CrossRef
  • Thyroid Cancer Epidemiology in South Spain: a population-based time trend study
    Elena Salamanca-Fernández, Miguel Rodriguez-Barranco, Yoe-Ling Chang-Chan, Daniel Redondo-Sánchez, Santiago Domínguez-López, Eloísa Bayo, Dariusz Narankiewicz, José Expósito, María José Sánchez
    Endocrine.2018; 62(2): 423.     CrossRef
  • 12,803 View
  • 309 Download
  • 35 Web of Science
  • 35 Crossref
Close layer
Original Article
Long Term Trends and the Future Gastric Cancer Mortality in Korea: 1983~2013
Yunhee Choi, Jin Gwack, Yeonju Kim, Jisuk Bae, Jae-Kwan Jun, Kwang-Pil Ko, Keun-Young Yoo
Cancer Res Treat. 2006;38(1):7-12.   Published online February 28, 2006
DOI: https://doi.org/10.4143/crt.2006.38.1.7
Correction in: Cancer Res Treat 2007;39(1):44
AbstractAbstract PDFPubReaderePub
Purpose

In spite of gastric cancer's decreasing incidence and mortality rates, it is still the most common cancer in Korea. In the present study, we examined the temporal trends of gastric cancer mortality during the past 20 years in Korea by using an age-period-cohort model, and we predicted the mortality rates for the next 10 years.

Materials and Methods

Data on the annual number of deaths due to gastric cancer and data on population statistics from 1984 to 2003 were obtained from the Korean National Statistical Office. A log-linear Poisson age-period-cohort model was used to estimate age, period and birth cohort effects. To project two periods (10 years) into the future, the new cohort values were estimated by performing linear regression that was applied to a chosen number of the most recent cohort values.

Results

The trends of gastric cancer mortality were predominantly explained by the cohort effect; the risk of gastric cancer death decreased since the 1919 birth cohort for both genders. The predicted, expected age-adjusted mortality rates per 100,000 for males and females are 45.72 and 23.75, respectively, during 2004~2008, and 34.62 and 17.93 respectively, during 2009~2013. During 2004~2008 and 2009~2013, the predicted numbers of deaths due to gastric cancer in males are 36,922 and 27,959, respectively, whereas those in females are 19,698 and 14,869, respectively.

Conclusions

Not only the mortality, but also the incidence of gastric cancer in Korea is expected to further decrease in both men and women if the trends of the past 20 years continue.

Citations

Citations to this article as recorded by  
  • Magnifying endoscopy is superior at detecting easy-missed neoplastic lesions on the upper gastrointestinal tract
    Bo Jin, Xiaoliang Jin, Liang Huang, Chunli Zhang, Bin Lyu
    Surgical Endoscopy.2023; 37(7): 5094.     CrossRef
  • Descriptive Analysis of Gastric Cancer Mortality in Korea, 2000-2020
    Tung Hoang, Hyeongtaek Woo, Sooyoung Cho, Jeeyoo Lee, Sayada Zartasha Kazmi, Aesun Shin
    Cancer Research and Treatment.2023; 55(2): 603.     CrossRef
  • Risk of lymph node metastasis and feasibility of endoscopic submucosal dissection in undifferentiated-type early gastric cancer
    Pengyue Zhang, Tingting Xu, Hui Feng, Zhen Zhu, Jingjing Wang, Yalei Wang
    BMC Gastroenterology.2023;[Epub]     CrossRef
  • Status of Endoscopic Screening Strategies for Upper Gastrointestinal Tract Cancer
    Bin Lyu, Xiao-Liang Jin
    Cancer Screening and Prevention.2022; 000(000): 000.     CrossRef
  • Clinical Features and Risk Factors for Lymph Node Metastasis in Early Signet Ring Cell Gastric Cancer
    Xiaoliang Jin, Wei Wu, Jing Zhao, Shuang Song, Chunli Zhang, Wenyong Sun, Bin Lv
    Frontiers in Oncology.2021;[Epub]     CrossRef
  • Operable gastric adenocarcinoma with different histological subtypes: Cancer-specific survival in the United States
    Chun-Lin Lin, Guang-Wei Zhu, Yong-Jian Huang, Wei Zheng, Shu-Gang Yang, Jian-Xin Ye
    Saudi Journal of Gastroenterology.2020; 26(1): 46.     CrossRef
  • Surgical Strategy and Outcome in Patients Undergoing Pancreaticoduodenectomy After Gastric Resection: A Three‐Center Experience with 39 Patients
    Dooin Lee, Jae Hoon Lee, Dongho Choi, Chang Moo Kang, Jae Uk Chong, Song‐Chul Kim, Kyeong Geun Lee
    World Journal of Surgery.2017; 41(2): 552.     CrossRef
  • Differential Prognostic Implications of Gastric Signet Ring Cell Carcinoma
    Hong Jae Chon, Woo Jin Hyung, Chan Kim, Sohee Park, Jie-Hyun Kim, Chan Hyuk Park, Joong Bae Ahn, Hyunki Kim, Hyun Cheol Chung, Sun Young Rha, Sung Hoon Noh, Hei-Cheul Jeung
    Annals of Surgery.2017; 265(5): 946.     CrossRef
  • Second primary malignancy risk among patients with gastric cancer: a nationwide population-based study in Taiwan
    San-Chi Chen, Chia-Jen Liu, Yu-Wen Hu, Chiu-Mei Yeh, Li-Yu Hu, Yen-Po Wang, Yi-Ping Hung, Cheng-Hwai Tzeng, Tzeon-Jye Chiou, Tzeng-Ji Chen, Chung-Jen Teng
    Gastric Cancer.2016; 19(2): 490.     CrossRef
  • Age and sex interactions in gastric cancer incidence and mortality trends in Korea
    Minkyo Song, Daehee Kang, Jae Jeong Yang, Ji-Yeob Choi, Hyuna Sung, Yunhee Lee, Hyung-Suk Yoon, Yunhee Choi, Seong-Ho Kong, Hyuk-Joon Lee, Han-Kwang Yang, Woo Ho Kim
    Gastric Cancer.2015; 18(3): 580.     CrossRef
  • Ultrasonically activated shears versus electrocautery in open gastrectomy for gastric cancer: a randomized controlled trial
    Min-Gew Choi, Seung Jong Oh, Jae Hyung Noh, Tae Sung Sohn, Sung Kim, Jae Moon Bae
    Gastric Cancer.2014; 17(3): 556.     CrossRef
  • The Effects ofHelicobacter pylorion the prognosis of patients with curatively resected gastric cancers in a population with high infection rate
    Hoon Hur, Sang Rim Lee, Yi Xuan, Young Bae Kim, Young Ae Lim, Yong Kwan Cho, Sang-Uk Han
    Journal of the Korean Surgical Society.2012; 83(4): 203.     CrossRef
  • Long‐term results and prognostic factors of gastric cancer patients with only positive peritoneal lavage cytology
    Cheong Ah Oh, Jae Moon Bae, Seung Jong Oh, Min Gew Choi, Jae Hyung Noh, Tae Sung Sohn, Sung Kim
    Journal of Surgical Oncology.2012; 105(4): 393.     CrossRef
  • Understanding the Rapid Increase in Life Expectancy in South Korea
    Seungmi Yang, Young-Ho Khang, Sam Harper, George Davey Smith, David A. Leon, John Lynch
    American Journal of Public Health.2010; 100(5): 896.     CrossRef
  • Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses
    Jin‐Hee Lee, Do‐Sun Byun, Min‐Goo Lee, Byung‐Kyu Ryu, Min‐Ju Kang, Kwon‐Seok Chae, Kil Yeon Lee, Hyo‐Jong Kim, Heonyong Park, Sung‐Gil Chi
    International Journal of Cancer.2008; 122(7): 1573.     CrossRef
  • Temporal Changes of Lung Cancer Mortality in Korea
    Yunhee Choi, Yeonju Kim, Yun-Chul Hong, Sue Kyung Park, Keun-Young Yoo
    Journal of Korean Medical Science.2007; 22(3): 524.     CrossRef
  • 9,511 View
  • 53 Download
  • 16 Crossref
Close layer
Cancer Res Treat : Cancer Research and Treatment
© Korean Cancer Association.
Close layer
TOP