Cancer Research and Treatment

Case Report

Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission: Won Sup Lee, Ji-Hyen Hwang, Moon Jin Kim, Se-Il Go, Anna Lee, Haa-Na Song, Min Jeong Lee, Myung Hee Kang, Hoon-Gu Kim, Jeong-Hee Lee; Cancer Res Treat. 2014;46(3):312-316. Published online July 15, 2014; DOI: https://doi.org/10.4143/crt.2014.46.3.312

Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. It is well-established that patients who are diagnosed with SPTL usually respond poorly to chemotherapy, showing fatal outcome. As a first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the treatment of SPTL, the efficacy of cyclosporine A has been recently reported in relapsed SPTL after anthracycline-based chemotherapy. However, it is still not clear whether cyclosporine A can be used as a first-line treatment against SPTL. Here, we report a case of SPTL, which achieved complete remission for nine years after first-line cyclosporine A therapy. This study suggests that cyclosporine A can induce a complete long-term remission as a first-line treatment.

Citations

Citations to this article as recorded by

The pathophysiology and current treatments for the subcutaneous panniculitis‐like T cell lymphoma: An updated review
En‐Cheng Lin, Jia‐Bin Liao, Yu‐Han Fang, Chien‐Hui Hong
Asia-Pacific Journal of Clinical Oncology.2023; 19(1): 27. CrossRef
A retrospective study of 18 children with subcutaneous panniculitis-like T-cell lymphoma: multidrug combination chemotherapy or immunomodulatory therapy?
Yanlong Duan, Huixia Gao, Chunju Zhou, Ling Jin, Jing Yang, Shuang Huang, Meng Zhang, Yonghong Zhang, Tianyou Wang
Orphanet Journal of Rare Diseases.2022;[Epub] CrossRef
Case Report—Indurated Plaques and Recurrent Fevers in a 37-Year-Old Man: Answer
Elizabeth Dao, Alexandra Bourgeois, Pamela Martin
The American Journal of Dermatopathology.2021; 43(10): 754. CrossRef
Hemophagocytic Lymphohistiocytosis as the Initial Presentation of Subcutaneous Panniculitis-Like T-Cell Lymphoma: A Rare Case Responding to Cyclosporine A and Steroids
Caitlin Sullivan, Arya Loghmani, Katharine Thomas, Rachna Jetly-Shridhar, Rajasree Pia Chowdry
Journal of Investigative Medicine High Impact Case Reports.2020;[Epub] CrossRef
Rare Cutaneous T-Cell Lymphomas
Fabiana Damasco, Oleg E. Akilov
Hematology/Oncology Clinics of North America.2019; 33(1): 135. CrossRef
Hematopoietic stem cell transplantation for subcutaneous panniculitis-like T-cell lymphoma: single center experience in an Asian population
Ting-An Lin, Ching-Fen Yang, Yao-Chung Liu, Jin-Hwang Liu, Tzeon-jye Chiou, Liang-Tsai Hsiao, Hsiu-Ju Yen, Chia-Jen Liu, Hao-Yuan Wang, Po-Shen Ko, Sheng-Hsuan Chien, Jyh-Pyng Gau
International Journal of Hematology.2019; 109(2): 187. CrossRef
Successful treatment of a rare subcutaneous panniculitis‐like T‐cell lymphoma: An unusual case report and literature review
Liye Xu, Yuxuan Che, Xiaolei Ding, Jincheng Song, Xian Zhang, Xiuhua Sun
Dermatologic Therapy.2019;[Epub] CrossRef
British Association of Dermatologists guidelines for the safe and effective prescribing of oral ciclosporin in dermatology 2018
J. Berth‐Jones, L.S. Exton, E. Ladoyanni, M.F. Mohd Mustapa, V.M. Tebbs, P.D. Yesudian, N.J. Levell, P.M. McHenry, T.A. Leslie, S. Wakelin, R.Y.P. Hunasehally, M. Cork, G.A. Johnston, N. Chiang, F.S. Worsnop, A. Salim, D. Buckley, G. Petrof, N. Callachand
British Journal of Dermatology.2019; 180(6): 1312. CrossRef
A Systematic Approach to the Cutaneous Lymphoid Infiltrates: A Clinical, Morphologic, and Immunophenotypic Evaluation
Alejandro A. Gru, Chauncey McHargue, Andrea L. Salavaggione
Archives of Pathology & Laboratory Medicine.2019; 143(8): 958. CrossRef
Hemophagocytic lymphohistiocytosis: A rare, potentially fatal complication in subcutaneous panniculitis like T cell lymphoma
ChandraSekhar Sirka, Swetalina Pradhan, Susama Patra, Somanath Padhi, SarojKumar DasMajumdar, Debjani Panda
Indian Journal of Dermatology, Venereology and Leprology.2019; 85(5): 481. CrossRef
Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas
Pilvi Maliniemi, Kirsi Laukkanen, Liisa Väkevä, Katja Dettmer, Tuomas Lipsanen, Leila Jeskanen, Alban Bessede, Peter J. Oefner, Marshall E. Kadin, Annamari Ranki
OncoImmunology.2017; 6(3): e1273310. CrossRef
Uncommon Variants of T-Cell Lymphomas
Neha Mehta-Shah, Steven Horwitz
Hematology/Oncology Clinics of North America.2017; 31(2): 285. CrossRef
Relapsed and refractory subcutaneous panniculitis-like T-cell lymphoma with excellent response to cyclosporine: a case report and literature review
Chi-Ching Chen, Chieh-Lin Teng, Su-Peng Yeh
Annals of Hematology.2016; 95(5): 837. CrossRef
Managing Patients with Cutaneous B-Cell and T-Cell Lymphomas Other Than Mycosis Fungoides
Meenal Kheterpal, Neha Mehta-Shah, Pooja Virmani, Patricia L. Myskowski, Alison Moskowitz, Steven M. Horwitz
Current Hematologic Malignancy Reports.2016; 11(3): 224. CrossRef
Zebras and hen's teeth: recognition and management of rare T and NK lymphomas
Neha Mehta–Shah, Steven Horwitz
Hematology.2015; 2015(1): 545. CrossRef

11,390 View
90 Download
16 Web of Science
15 Crossref

First
Prev
Page of 1
Next
Last

Search