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2 "Min Jae Kim"
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Original Article
Clinicopathologic Features of Metachronous or Synchronous Gastric Cancer Patients with Three or More Primary Sites
Joo Hoon Kim, Sun Young Rha, Chan Kim, Gun Min Kim, Sang Hyun Yoon, Ki Hyang Kim, Min Jae Kim, Joong Bae Ahn, Hyun Cheol Chung, Jae Kyung Roh, Hyo Song Kim
Cancer Res Treat. 2010;42(4):217-224.   Published online December 31, 2010
DOI: https://doi.org/10.4143/crt.2010.42.4.217
AbstractAbstract PDFPubReaderePub
Purpose

We investigated the clinicopathologic information of patients with gastric cancer with multiple primary cancers (GC-MPC) of three or more sites.

Materials and Methods

Between 1995 and 2009, 105,908 patients were diagnosed with malignancy at Severance Hospital, Yonsei University Health System. Of these, 113 (0.1%) patients with MPC of three or more sites were registered, and 41 (36.3%) of these were GC-MPC. We retrospectively reviewed the clinical data and overall survival using the medical records of these 41 GC-MPC patients. We defined synchronous cancers as those occurring within 6 months of the first primary cancer, while metachronous cancers were defined as those occurring more than 6 months later.

Results

Patients with metachronous GC-MPC were more likely to be female (p=0.003) and young than patients with synchronous GC-MPC (p=0.013). The most common cancer sites for metachronous GC-MPC patients were the colorectum, thyroid, lung, kidney and breast, while those for synchronous GC-MPC were the head and neck, esophagus, lung, and kidney. Metachronous GC-MPC demonstrated significantly better overall survival than synchronous GC-MPC, with median overall survival durations of 4.7 and 14.8 years, respectively, and 10-year overall survival rates of 48.2% and 80.7%, respectively (p<0.001).

Conclusion

Multiplicity of primary malignancies itself does not seem to indicate a poor prognosis. The early detection of additional primary malignancies will enable proper management with curative intent.

Citations

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    Journal of Gastrointestinal Surgery.2020; 24(7): 1499.     CrossRef
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  • 27 Crossref
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Case Report
A Case of Metachronous Metastasis to the Breast from Non-Small Cell Lung Carcinoma
Min Yong Yoon, Chang Seok Song, Mi Hae Seo, Min Jae Kim, Tae Yun Oh, Un Ha Jang, Hyon Joo Kwag, Hee Sung Kim, Si Young Lim, Seong Yong Lim, Seung Sae Lee
Cancer Res Treat. 2010;42(3):172-175.   Published online September 30, 2010
DOI: https://doi.org/10.4143/crt.2010.42.3.172
AbstractAbstract PDFPubReaderePub

Breast metastases from an extramammary primary tumor are very rare and the prognosis for such patients is generally poor. We report here on a case of a 42-year-old female with metastasis of non-small cell lung cancer to the breast, and she is now being followed up on an outpatient basis. In 2004, she presented with a solitary pulmonary nodule in the left lung, and this lesion had been noted to have gradually increased in size over time. The final pathological diagnosis was adenocarcinoma, and the diagnosis was made by performing percutaneous needle aspiration and lobectomy of the left upper lobe. Adjuvant chemotherapy and radiotherapy were given. Unfortunately, a nodule in the left breast was noted three years later, and metastatic non-small-cell lung cancer to the breast was diagnosed by excisional biopsy. Making the correct diagnosis to distinguish a primary breast carcinoma from a metastatic one is important, because the therapeutic plan and outcome for these two types of cancer are quite different.

Citations

Citations to this article as recorded by  
  • A Rare Case of Breast Metastasis from a Primary Lung Tumor: Case Report
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  • 65 Download
  • 7 Crossref
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