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J Korean Cancer Assoc > Volume 28(6); 1996 > Article
Journal of the Korean Cancer Association 1996;28(6): 1050-1055.
근치적 절제술을 시행받은 위암환자에서 수술전 혈청 CEA 치의 측정
최진혁, 이선영, 심강섭, 손혜영, 이기현, 김종선, 박진아, 홍은순, 김효정, 박수영, 황민규, 심광섭
Determination of Preoperative Serum CEA Level in Curativeal Resected Gastric Cancer
Jin Hyuk Choi, Sun Young Lee, Kang Sup Shim, Hye Young Son, Ki Youl Seo, Jong Seon Kim, Jin Ah Park, Eun Soon Hong, Hyo Jeong Kim, Su Young Park, Min Gyeu Hwang, Kang Sup Shim
ABSTRACT
Background: Although the role of serum carcinoembryonic antigen(CEA) as a tumor marker in gastric cancer remains unanswered, several reports suggested the usefulness of serum CEA as prognostic factor or indicator of recurrence.
Method:
Preoperative serum levels of CEA were determined in 79 patients with curatively resected gastric cancer and its correlation with clinicopathologic characteristics was investigated.
Results:
Serum CEA was positive(defined as>5ng/ml) in 16 patients(20.3%). The mean age of CEA positive group(62.9¡¾7.5 years) was significantly older than that of the negative group(53.2¡¾12.7 years)(p=0.005), and Borrmann type III cases were more frequent in CEA positive group(56.3% vs. 19.0%)(p=0.026). There were no significant differences between two groups in other clinicopathologic characteristics, including tumor size, tumor location, differentiation of tumor, and stages.
Conclusion:
Serum CEA does not seem to be standard. tumor marker of gastric cancer, in terms of screening or diagnosis. However, it could be useful as prognostic factor or for early detection of recurrence in curatively resected gaxtric cancer
Key words: Gastric cancer, Curative resection, CEA, Prognostic factor, Detection of recurrence
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