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J Korean Cancer Assoc > Volume 26(3); 1994 > Article
Journal of the Korean Cancer Association 1994;26(3): 415-425.
유방보존 수술 후 유방암의 재발
김지연, 장일성
The Recurrence of Breast Cancer after the Breast Conservation Surgery
Ji Yeon Kim, Eil Sang Chang
ABSTRACT
Breast cancer, like many other cancers, often follows a tortuous course marked by remissions and subseguent recurrences and, its disease free interval is of varying duration. There are several clinical factors which might be associated with recurrence of breast cancer such as tumor size, axillary 1ymph node involvement, histologic type, patient age and selected treatment modalities. But it is not yet settled that a certain factor closely related with recurrence among those prognostic factors. For this reason, we had carried out this clinical study for the purpose of knowing such factors during the period from March of 1990 to February of 1993 at department of Surgery, College of Medicine, Chungnam National University. 50 cases out of l41 breast cancer patients who had recieved the breast conservation surgery were elected for this study. By the time of follw-up, recurrence had occurred of 7 of those 50 patients, for an incidence of 14%. The sites of vast majority of locoregional recurrence at the time of discovery were interpectoral nodes and remnant breast. The supraclavicular nodes, contralateral breast and skin of forearm were the sites of systemic recurrence. The most common symptoms of reccurence at the time of discovery was the palpable mass, and the others were erythematous skin change on forearm. But, in one case, there was not any symptoms except that a certain recurrence had been suspected on mammographic finding. The tumor size lesser than 2 cm(T2)had a recurrence rate af 8.3%, compared with 13.6% for those larger than 2 cm(T,). The rateof recurrece for N, N, and N were 10.3%, 13.3% and 33.3%, respectively. The recurrence rate according to treatment modalities were 7.7% in surgery with chemotherapy group, 20% in combination of surgery, chemotherapy and Tamoxifen, 14.3% in combination of surgery, chemotherapy and radiotherapy. But, there was not noted any recurrence in patients with combination of surgery, chemotherapy, radiotherapy and Tamoxifen. The disease free intervals were more shorter in larger tumor size, more involvement of axillary lymph nodes, and in the invasize lobular carcinoma on histopathology. But, the interval was not related with the patients age and the radiotherapy.
Key words: Recurrence, Breast conservation surgery
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