Twenty-eight cases of malignant melanoma were treated at this hospital during the period from 1978 to 1987. An analysis of this clinical material revealed the followings. 1) The incidence of this cancer was far less common than in the west, comprising only 0.4% of all registered cancer patients at Department of GerneraI Surgery in SNVH. 2) The sex ratio was almost equal, and the disease was most often diagnosed in the sixth decade of life. 3) Twenty-six cases were cutaneous melanoma, and two cases were mucosal melanoma. 4) Main clinical symptoms were change in size or contour of nevus and unhealed ulcer. 5) Most freuqent primary site was lower extremity. 6) Almost all patients symptom duration was less than one year. 7) Most frequently used treatment modality was combination on wide excision, regional lymph node dissection, and adjuvant therapy. 8) Frquently metastatic sites of malignant melanoma were regional lymph node (17), Liver (5), lung (4), bone (4), other site of skin (2), and brain (1). 9) The determinate survivai af cutaneous melanoma was 36.1 months and mucosal melanoma was 31.5 months. 1(l) The determinate survivai of malienant melanoma, according to clinical stage were stage I cases 44.6 months, stage II cases 36.1 months and stage Ill cases 15.6 months. 11) The disease free interval of malignant melanoma, were cutaneous melanoma 19.4 months and mucosal melanoma 24 montha 12) The disease free interval of malignant melanoma according to clinical stage were stage I cases 26.5 months, stage II cases 22.1 months and stage III cases 6.4 months. 13) Those factors like stage I and II, less than 0.76 mm, thick and below Clark level II revealed good prognostic indicators.
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