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J Korean Cancer Assoc > Volume 18(1); 1986 > Article
Journal of the Korean Cancer Association 1986;18(1): 29-35.
원발성간세포암의 진단에 있어서 혈청 Ferritin 측정의 의의
유재화, 양상호, 박요한, 구자영, 박병채
Clinical Significance of Serum Ferritin Determination in the Diagnosis of Primary Hepatocellular Carcinome
Jae Hwa Ryu, Sang Ho Yang, Yo Han Park, Ja Young Koo, Byung Chae Park
In an attempt to verify the possibility that serum ferritin and serum ferritin/transamin- ases ratio might be an useful marker in the diagnosis of primary hepatocellular carcinoma, we checked serum ferritin level as well as serum ferritin/transaminases ratio in 52 Patients with chronic liver diseases including primary hepatocellular carcinoma. Serum ferritin level in patients with liver cirrhosis(28l+- 4.83ug/L, mean: SE) and with hepatocellular carcinoma(321+- 29.73 ug/L, mean -SE) were significantly(p(0. 0005) elevated in comparison to normal control group(78. 33+-4. 24 ug/L, mean SE), but no statistical significance was observed between the patient groups of liver cirrhosis and hepatocellular carcinoma. Moreover, we also failed to observe a significant difference of serum ferritin/transaminases ratio in patients with liver cirrhosis(8.30+-1.63, mean SE) and with hepatocellular carcinoma(8.46+-1.62, mean+-SE). The results of this study, therefore, would indicate that serum ferritin determination seems to be not helful in the differential diagnosis of primary hepatocellular carcinoma.
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