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J Korean Cancer Assoc > Volume 30(3); 1998 > Article
Journal of the Korean Cancer Association 1998;30(3): 608-612.
A Case of Placental Metastasis from Advanced Gastric Carcinoma
Mi Sook Lee, Sang Hee Kim, Je Hwan Lee, Sung Bae Kim, Cheol Won Suh, Kyoo Hyung Lee, Jung Shin Lee, Woo Kun Kim, Sang We Kim
Department of Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Placental and fetal involvement by matenal malignancy is rare. We report a case of placental metastasis from advanced gastric carcinoma in a 27 year-old woman. The patient also had disseminated bone metastasis, bone marrow involvement, malignant ascites, multiple lymphadenopathy, and disseminated intravascular coagulopathy. Cut surface of the placental body showed many, variable-sized, grayish white nodules and plaques. Light microscopic finding showed sheets of poorly differentiated adenocarcinoma in intervillous spaces. Villi were not invaded. Despite palliative chemotherapy the patient died of massive gastric cancer bleeding. But the patients child is alive and doing well with age of 11 months. We suggest that the presence of malignancy in pregnancy demands complete evaluation of the placenta and adequate follow-up of the infant for the sign of involvement.
Key words: Placental metastasis;Advanced gastric carcinoma
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