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Drug Resistance to 5 - Fluorouracil and Overexpression of Thymidylate Synthase mRNA in Human Gastrointestinal Malignancies
Tae You Kim, Baek Yeol Ryoo, Yung Hyuck Im, Yoon Koo Kang, Sang Jae Lee, Yung Jue Bang, Noe Kyeong Kim
Cancer Research and Treatment. 2000;32(1):44-52.

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Escherichia coli thymidylate synthase expression protects human cells from the cytotoxic effects of 5-fluorodeoxyuridine more effectively than human thymidylate synthase overexpression
Cancer Gene Therapy. 2000;7(8):1179-1187   Crossref logo
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High Expression of Thymidylate Synthase Leads to Resistance to 5-Fluorouracil in Biliary Tract Carcinomain vitro
Japanese Journal of Cancer Research. 2001;92(10):1127-1132   Crossref logo

Association of Time to Recurrence With Thymidylate Synthase and Dihydropyrimidine Dehydrogenase mRNA Expression in Stage II and III Colorectal Cancer
Journal of Gastrointestinal Surgery. 2002;6(3):331-337   Crossref logo
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Drug Resistance Against Tyrosine Kinase Inhibitor in Gastrointestinal Malignancies
Role of Tyrosine Kinases in Gastrointestinal Malignancies. 2018;191-224   Crossref logo

Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil
Biochemical Pharmacology. 1995;49(10):1419-1426   Crossref logo
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Fragment-based discovery of novel thymidylate synthase leads by NMR screening and group epitope mapping
Chemical Biology & Drug Design. 2010;no-no   Crossref logo

Retroviral Transduction of a Mutant Dihydrofolate Reductase-Thymidylate Synthase Fusion Gene into Murine Marrow Cells Confers Resistance to Both Methotrexate and 5-Fluorouracil
Human Gene Therapy. 2003;14(5):435-446   Crossref logo

Resistance to Inhibitor Compounds of Thymidylate Synthase
Encyclopedia of Cancer. 2002;107-113   Crossref logo
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High expression of thymidylate synthase is Associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy
Cancer. 1998;82(9):1626-1631   Crossref logo
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Repression of Human Thymidylate Synthase mRNA Translation by Antisense 2′-O-Methyl Oligoribonucleotides
Antisense and Nucleic Acid Drug Development. 1998;8(5):371-378   Crossref logo

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