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Trastuzumab Combined with Irinotecan in Patients with HER2-Positive Metastatic Colorectal Cancer: A Phase II Single-Arm Study and Exploratory Biomarker Analysis

Ting Xu, Xicheng Wang, Ying Xin, Zhenghang Wang, Jifang Gong, Xiaotian Zhang, Yanyan Li, Congcong Ji, Yu Sun, Feilong Zhao, Depei Huang, Yuezong Bai, Jian Li, Lin Shen

Cancer Research and Treatment. 2023;55(2):626-635. Published online 2022 December 23 DOI: https://doi.org/10.4143/crt.2022.1058

Trastuzumab Combined with Irinotecan in Patients with HER2-Positive Metastatic Colorectal Cancer: A Phase II Single-Arm Study and Exploratory Biomarker Analysis

Ting Xu, Xicheng Wang, Ying Xin, Zhenghang Wang, Jifang Gong, Xiaotian Zhang, Yanyan Li, Congcong Ji, Yu Sun, Feilong Zhao, Depei Huang, Yuezong Bai, Jian Li, Lin Shen

Cancer Research and Treatment. 2023;55(2):626-635

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523TiP MOUNTAINEER: Open-label, phase II study of tucatinib combined with trastuzumab for HER2-positive metastatic colorectal cancer

J. Strickler, K. Ng, A. Cercek, C. Fountzilas, F. Sanchez, J. Hubbard, C. Wu, M. Stecher, L.N. Walker, T. Bekaii-Saab

Annals of Oncology. 2020;31:S460-S461

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Pyrotinib combined with trastuzumab and chemotherapy for the treatment of human epidermal growth factor receptor 2-positive metastatic breast cancer: a single-arm exploratory phase II trial

Xiao-Feng Xie, Qiu-Yi Zhang, Jia-Yi Huang, Li-Ping Chen, Xiao-Feng Lan, Xue Bai, Lin Song, Shui-Ling Xiong, Si-Jia Guo, Cai-Wen Du

. 2022;

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Pertuzumab and Trastuzumab in Combination with Vinorelbine for First-Line Treatment of Patients with HER2-Positive Locally Advanced or Metastatic Breast Cancer (LABC/MBC): A Single-Arm, Two-Cohort, Phase II Study (Velvet)

M. Andersson, J.M. Lopez-Vega, L. Del Mastro, T. Petit, L. Mitchell, C. Pelizon, E.A. Perez

Annals of Oncology. 2012;23:ix142

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244P Eribulin combined with anlotinib for patients with HER2-negative metastatic breast cancer: A single-arm, multicenter, phase II study

Y. Yin, X. Wu, X. Huang, W. Li, Y. Hua, Y. Liang

Annals of Oncology. 2022;33:S648-S649

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Dual HER2 Targeted Therapy With Pyrotinib and Trastuzumab in Refractory HER2 Positive Metastatic Colorectal Cancer: A Result From HER2-FUSCC-G Study

Jinjia Chang, Midie Xu, Chenchen Wang, Dan Huang, Zhe Zhang, Zhiyu Chen, Xiaodong Zhu, Wenhua Li

Clinical Colorectal Cancer. 2022;21(4):347-353

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192P A phase II single-arm clinical study of neoadjuvant treatment with pegylated liposomal doxorubicin (PLD) plus cyclophosphamide (C) combined with trastuzumab (H) and pertuzumab (P) in HER2-positive (HER2+) breast cancer (BC)

Y. Yang, L. Jin, N. Rao, C. Gong, S. Li, Y. Li, J. Wu, J. Zhao, L. Ding, Q. Liu

Annals of Oncology. 2022;33:S624

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Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer

Edith A Perez, Sara A Hurvitz, Lukas C Amler, Kirsten E Mundt, Vivian Ng, Ellie Guardino, Luca Gianni

Breast Cancer Research. 2014;16(3):

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Phase II study of trastuzumab with irinotecan in HER2-positive gastric cancer previously treated with trastuzumab

Kazuteru Hatanaka, Yasuyuki Kawamoto, Satoshi Yuki, Takashi Meguro, Minoru Uebayashi, Masakazu Abe, Michio Nakamura, Hiroyuki Okuda, Yuh Sakata, Yoshito Komatsu

Annals of Oncology. 2017;28:ix93

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Phase 2, Multicenter, Single-Arm Study of Eribulin Mesylate With Trastuzumab as First-Line Therapy for Locally Recurrent or Metastatic HER2-Positive Breast Cancer

Sharon Wilks, Shannon Puhalla, Joyce O'Shaughnessy, Lee Schwartzberg, Erhan Berrak, James Song, David Cox, Linda Vahdat

Clinical Breast Cancer. 2014;14(6):405-412

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