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NUDT15 Variants Cause Hematopoietic Toxicity with Low 6-TGN Levels in Children with Acute Lymphoblastic Leukemia
Eun Sang Yi, Young Bae Choi, Rihwa Choi, Na Hee Lee, Ji Won Lee, Keon Hee Yoo, Ki Woong Sung, Soo-Youn Lee, Hong Hoe Koo
Cancer Research and Treatment. 2018;50(3):872-882.   Published online 2017 September 13    DOI:

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NUDT15 Variants Cause Hematopoietic Toxicity with Low 6-TGN Levels in Children with Acute Lymphoblastic Leukemia
Cancer Research and Treatment. 2018;50(3):872-882   Crossref logo
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ITPA, TPMT, and NUDT15 Genetic Polymorphisms Predict 6-Mercaptopurine Toxicity in Middle Eastern Children With Acute Lymphoblastic Leukemia
Frontiers in Pharmacology. 2019;10:   Crossref logo

Emerging role of NUDT15 polymorphisms in 6-mercaptopurine metabolism and dose related toxicity in acute lymphoblastic leukaemia
Leukemia Research. 2017;62:17-22   Crossref logo
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Association of NUDT15 c.415C>T and FPGS 2572C>T Variants with the Risk of Early Hematologic Toxicity During 6-MP and Low-Dose Methotrexate-Based Maintenance Therapy in Indian Patients with Acute Lymphoblastic Leukemia
Genes. 2020;11(6):594   Crossref logo

Effects of TPMT, NUDT15, and ITPA Genetic Variants on 6-Mercaptopurine Toxicity for Pediatric Patients With Acute Lymphoblastic Leukemia in Yunnan of China
Frontiers in Pediatrics. 2021;9:   Crossref logo

Significance of TPMT and NUDT15 variants in 6-mercaptopurine metabolism in acute lymphoblastic leukaemia/lymphoma patients
Russian journal of hematology and transfusiology. 2021;66(2):253-262   Crossref logo

Development of BCR-ABL positive acute lymphoblastic leukemia in donor cells after allogeneic hematopoietic cell transplantation for Philadelphia-positive acute lymphoblastic leukemia
Bone Marrow Transplantation. 2004;34(2):189-191   Crossref logo
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Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia
The Pharmacogenomics Journal. 2017;18(2):275-280   Crossref logo
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The Effect of NUDT15, TPMT, APEX1, and ITPA Genetic Variations on Mercaptopurine Treatment of Pediatric Acute Lymphoblastic Leukemia
Children. 2021;8(3):224   Crossref logo

Expression of Tel-Aml1 transcript variants in pediatric acute lymphoblastic leukemia
Leukemia. 2005;20(1):165-167   Crossref logo
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