PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane–Based Neoadjuvant Chemotherapy
Sanxing Guo, Sibylle Loibl, Gunter von Minckwitz, Silvia Darb-Esfahani, Bianca Lederer, Carsten Denkert
Cancer Res Treat. 2020;52(3):689-696.   Published online 2020 Feb 4     DOI: https://doi.org/10.4143/crt.2019.497
Citations to this article as recorded by Crossref logo
Atezolizumab in Combination With Carboplatin and Survival Outcomes in Patients With Metastatic Triple-Negative Breast Cancer
Brian D. Lehmann, Vandana G. Abramson, E. Claire Dees, Payal D. Shah, Tarah J. Ballinger, Claudine Isaacs, Cesar A. Santa-Maria, Hanbing An, Paula I. Gonzalez-Ericsson, Melinda E. Sanders, Kimberly C. Newsom, Richard G. Abramson, Quanhu Sheng, Chih-Yuan H
JAMA Oncology.2024; 10(2): 193.     CrossRef
Circulating tumour mutation detection in triple-negative breast cancer as an adjunct to tissue response assessment
Elena Zaikova, Brian Y. C. Cheng, Viviana Cerda, Esther Kong, Daniel Lai, Amy Lum, Cherie Bates, Wendie den Brok, Takako Kono, Sylvie Bourque, Angela Chan, Xioalan Feng, David Fenton, Anagha Gurjal, Nathalie Levasseur, Caroline Lohrisch, Sarah Roberts, Ta
npj Breast Cancer.2024;[Epub]     CrossRef
Somatic Mutations in Latin American Breast Cancer Patients: A Systematic Review and Meta-Analysis
Gabriela A. Martínez-Nava, Laura Keren Urbina-Jara, Saúl Lira-Albarrán, Henry L. Gómez, Erika Ruiz-García, María Tereza Nieto-Coronel, Rocio Ortiz-Lopez, Kenia Nadiezhda Martínez Villalba, Mariana Muñoz-Sánchez, Dione Aguilar, Liliana Gómez-Flores-Ramos,
Diagnostics.2024; 14(3): 287.     CrossRef
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein
John M. Ketcham, Stephen J. Harwood, Ruth Aranda, Athenea N. Aloiau, Briana M. Bobek, David M. Briere, Aaron C. Burns, Kersti Caddell Haatveit, Andrew Calinisan, Jeffery Clarine, Adam Elliott, Lars D. Engstrom, Robin J. Gunn, Anthony Ivetac, Benjamin Jone
Journal of Medicinal Chemistry.2024; 67(6): 4936.     CrossRef
Prevalence and effect of PIK3CA H1047R somatic mutation among Indian head and neck cancer patients
Arjita Ghosh, Anbalagan Moorthy
Saudi Journal of Biological Sciences.2024; 31(8): 104029.     CrossRef
Prognostic Factors for Triple-Negative Breast Cancer with Residual Disease after Neoadjuvant Chemotherapy
Zhijun Li, Yiqun Han, Jiayu Wang, Binghe Xu
Journal of Personalized Medicine.2023; 13(2): 190.     CrossRef
Triple-Negative Breast Cancer and Predictive Markers of Response to Neoadjuvant Chemotherapy: A Systematic Review
Nadine S. van den Ende, Anh H. Nguyen, Agnes Jager, Marleen Kok, Reno Debets, Carolien H. M. van Deurzen
International Journal of Molecular Sciences.2023; 24(3): 2969.     CrossRef
A light-up fluorescence platform based DNA: RNA hybrid G-quadruplet for detecting single nucleotide variant of ctDNA and miRNA-21
Gaihua Cao, Keyi Long, Yue Qiu, Lan Peng, Haiyan Han, Yongzhong Wang, Danqun Huo, Changjun Hou
Talanta.2023; 257: 124373.     CrossRef
Phosphoinositide 3-Kinase (PI3K) Inhibitors and Breast Cancer: An Overview of Current Achievements
Alexandre Bertucci, François Bertucci, Anthony Gonçalves
Cancers.2023; 15(5): 1416.     CrossRef
Identification of Kinase Targets for Enhancing the Antitumor Activity of Eribulin in Triple-Negative Breast Cell Lines
Xuemei Xie, Jangsoon Lee, Jon A. Fuson, Huey Liu, Toshiaki Iwase, Kyuson Yun, Cori Margain, Debu Tripathy, Naoto T. Ueno
Biomedicines.2023; 11(3): 735.     CrossRef
Synergistic actions of Alpelisib and Melatonin in breast cancer cell lines with PIK3CA gene mutation
Bianca Lara Venâncio de Godoy, Marina Gobbe Moschetta-Pinheiro, Luiz Gustavo de Almeida Chuffa, Noam Falbel Pondé, Russel J. Reiter, Jucimara Colombo, Debora Aparecida Pires de Campos Zuccari
Life Sciences.2023; 324: 121708.     CrossRef
Molecularly Targeted Therapies for Triple Negative Breast Cancer: History, Advances, and Future Directions
Nicholas Mai, Nour Abuhadra, Komal Jhaveri
Clinical Breast Cancer.2023; 23(8): 784.     CrossRef
Role of epigenetics variation with focus on DNA methylation in triple-negative breast cancer patients
GDeepthi Reddy, V Brahmaiah, BY Kavitha, Jayalatha Nethagani, ElizabethCaroline Palaparthi, RajasekharReddy Lebaka, G Deepika
Archives of Medicine and Health Sciences.2023; 11(1): 96.     CrossRef
Potential Protective Role of Melatonin in Benign Mammary Cells Reprogrammed by Extracellular Vesicles from Malignant Cells
Caroline Procópio de Oliveira, Barbara Maria Frigieri, Heidge Fukumasu, Luiz Gustavo de Almeida Chuffa, Adriana Alonso Novais, Debora Aparecida Pires de Campos Zuccari
Biomedicines.2023; 11(10): 2837.     CrossRef
Sclerosing Polycystic Adenoma: Conclusive Clinical and Molecular Evidence of Its Neoplastic Nature
Juan C. Hernandez-Prera, Daryoush Saeed-Vafa, Amin Heidarian, Kathleen Gewandter, Kristen Otto, Bruce M. Wenig
Head and Neck Pathology.2022; 16(2): 416.     CrossRef
PIK3CA Mutations in Diffuse Gliomas: An Update on Molecular Stratification, Prognosis, Recurrence, and Aggressiveness
Cheila Brito, Ana Tomás, Ana Azevedo, Susana Esteves, Manuela Mafra, Lúcia Roque, Marta Pojo
Clinical Medicine Insights: Oncology.2022; 16: 117955492110688.     CrossRef
Baseline Mutations and Up-Regulation of PI3K-AKT Pathway Serve as Potential Indicators of Lack of Response to Neoadjuvant Chemotherapy in Stage II/III Breast Cancer
Menghao Dong, Benjie Shan, Xinghua Han, Xiaotian Zhao, Fufeng Wang, Liuqing Zhu, Qiuxiang Ou, Xiaopeng Ma, Yueyin Pan
Frontiers in Oncology.2022;[Epub]     CrossRef
Clinical and morphological features of breast tumors with PIK3CA mutations in Russian patients: Observational study
Tatyana N. Sokolova, Tatyana I. Solov'eva, Svetlana N. Aleksakhina, Marina B. Bolieva, Viktor E. Goldberg, Marianna V. Kibisheva, Konstantin V. Menshikov, Dmitrii V. Ryazanov, Aleksandr V. Shkradyuk, Yana S. Chapko, Anna A. Shchukina, Idris M. Khabr
Journal of Modern Oncology.2022; 24(1): 12.     CrossRef
PIK3CAMutations in Breast Cancer Subtypes Other Than HR-Positive/HER2-Negative
Liliana Ascione, Paola Zagami, Eleonora Nicolò, Edoardo Crimini, Giuseppe Curigliano, Carmen Criscitiello
Journal of Personalized Medicine.2022; 12(11): 1793.     CrossRef
Precision Medicine and Triple-Negative Breast Cancer: Current Landscape and Future Directions
Fokhrul Hossain, Samarpan Majumder, Justin David, Lucio Miele
Cancers.2021; 13(15): 3739.     CrossRef
Single-nucleotide variant of PIK3CA H1047R gene assay by CRISPR/Cas12a combined with rolling circle amplification
Gaihua Cao, Xiaolong Chen, Yuanyi Deng, Fuping Nie, Yin Liu, Guoming Wang, Danqun Huo, Changjun Hou
Analytica Chimica Acta.2021; 1182: 338943.     CrossRef
Identification of effective natural PIK3CA H1047R inhibitors by computational study
Naimeng Liu, Xinhui Wang, Xuan Li, Xiaye Lv, Haoqun Xie, Zhen Guo, Jing Wang, Gaojing Dou, Ye Du, Dong Song
Aging.2021; 13(16): 20246.     CrossRef
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment
Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe,
Nature Communications.2021;[Epub]     CrossRef
Molecular Biomarkers Predict Pathological Complete Response of Neoadjuvant Chemotherapy in Breast Cancer Patients: Review
Ana Julia Aguiar de Freitas, Rhafaela Lima Causin, Muriele Bertagna Varuzza, Cassio Murilo Trovo Hidalgo Filho, Vinicius Duval da Silva, Cristiano de Pádua Souza, Márcia Maria Chiquitelli Marques
Cancers.2021; 13(21): 5477.     CrossRef
Clinical value and potential mechanisms of COL8A1 upregulation in breast cancer: a comprehensive analysis
Wei Peng, Jian-Di Li, Jing-Jing Zeng, Xiao-Ping Zou, Deng Tang, Wei Tang, Min-Hua Rong, Ying Li, Wen-Bin Dai, Zhong-Qing Tang, Zhen-Bo Feng, Gang Chen
Cancer Cell International.2020;[Epub]     CrossRef
Novel miRNA Targets and Therapies in the Triple-Negative Breast Cancer Microenvironment: An Emerging Hope for a Challenging Disease
Amal Qattan
International Journal of Molecular Sciences.2020; 21(23): 8905.     CrossRef