Cancer Research and Treatment

Neutrophil–lymphocyte ratio reflects tumour‐infiltrating lymphocytes and tumour‐associated macrophages and independently predicts poor outcome in breast cancers with neoadjuvant chemotherapy

Joshua J X Li, Shelly Y B Ni, Julia Y S Tsang, Wai Yin Chan, Ray K W Hung, Joshua W H Lui, Sally W Y Ng, Leong Kwong Shum, Ying Fei Tang, Gary M Tse

Circulating blood biomarkers correlated with the prognosis of advanced triple negative breast cancer

Xingyu Li, Yanyan Zhang, Cheng Zhu, Wentao Xu, Xiaolei Hu, Domingo Antonio Sánchez Martínez, José Luis Alonso Romero, Ming Yan, Ying Dai, Hua Wang

Recent advancements in nanoconstructs for the theranostics applications for triple negative breast cancer

Ashutosh Gupta, Kumar Nishchaya, Moumita Saha, Gaurisha Alias Resha Ramnath Naik, Sarika Yadav, Shreya Srivastava, Amrita Arup Roy, Sudheer Moorkoth, Srinivas Mutalik, Namdev Dhas

Journal of Drug Delivery Science and Technology.2024; 93: 105401. CrossRef

Predictive value of stromal tumor-infiltrating lymphocytes in patients with breast cancer treated with neoadjuvant chemotherapy: A meta-analysis

Guangfa Xia, Ziran Zhang, Qin Jiang, Huan Wang, Jie Wang

Pathology of neoadjuvant therapy and immunotherapy testing for breast cancer

Recent Advances in Targeted Nanocarriers for the Management of Triple Negative Breast Cancer

Rajesh Pradhan, Anuradha Dey, Rajeev Taliyan, Anu Puri, Sanskruti Kharavtekar, Sunil Kumar Dubey

The prognostic value of tumour-infiltrating lymphocytes, programmed cell death protein-1 and programmed cell death ligand-1 in Stage I–III triple-negative breast cancer

Guang-Yi Sun, Jing Zhang, Bing-Zhi Wang, Hao Jing, Hui Fang, Yu Tang, Yong-Wen Song, Jing Jin, Yue-Ping Liu, Yuan Tang, Shu-Nan Qi, Bo Chen, Ning-Ning Lu, Ning Li, Ye-Xiong Li, Jian-Ming Ying, Shu-Lian Wang

British Journal of Cancer.2023; 128(11): 2044. CrossRef

Effect of neoadjuvant chemotherapy on tumor immune infiltration in breast cancer patients: Systematic review and meta-analysis

Manuela Llano-León, Laura Camila Martínez-Enriquez, Oscar Mauricio Rodríguez-Bohórquez, Esteban Alejandro Velandia-Vargas, Nicolás Lalinde-Ruíz, María Alejandra Villota-Álava, Ivon Johanna Rodríguez-Rodríguez, María del Pilar Montilla-Velásquez, Carlos Al

Association of neutrophil-to-lymphocyte ratio with clinical, pathological, radiological, laboratory features and disease outcomes of invasive breast cancer patients: A retrospective observational cohort study

Sarosh Khan Jadoon, Rufina Soomro, Muhammad Nadeem Ahsan, Raja Muhammad Ijaz Khan, Sadia Iqbal, Farah Yasmin, Hala Najeeb, Nida Saleem, Namiya Cho, Resham, Taha Gul Shaikh, Syeda Fatima Saba Hasan, Muhammad Zain Khalid, Sarosh Alvi, Ahsan Mujtaba Rizvi,

A new prognostic model including immune biomarkers, genomic proliferation tumor markers (AURKA and MYBL2) and clinical-pathological features optimizes prognosis in neoadjuvant breast cancer patients

Esmeralda García-Torralba, Esther Navarro Manzano, Gines Luengo-Gil, Pilar De la Morena Barrio, Asunción Chaves Benito, Miguel Pérez-Ramos, Beatriz Álvarez-Abril, Alejandra Ivars Rubio, Elisa García-Garre, Francisco Ayala de la Peña, Elena García-Martínez

Tumor infiltrating lymphocytes and neutrophil-to-lymphocyte ratio in relation to pathological complete remission to neoadjuvant therapy and prognosis in triple negative breast cancer

Meng Zhao, Hui Xing, Jiankun He, Xinran Wang, Yueping Liu

Pathology - Research and Practice.2023; 248: 154687. CrossRef

Minimal residual disease in advanced or metastatic solid cancers: The G0-G1 state and immunotherapy are key to unwinding cancer complexity

Andrea Nicolini, Giuseppe Rossi, Paola Ferrari, Angelo Carpi

The advanced lung cancer inflammation index is a novel independent prognosticator in colorectal cancer patients after curative resection

Taichi Horino, Ryuma Tokunaga, Yuji Miyamoto, Yukiharu Hiyoshi, Takahiko Akiyama, Nobuya Daitoku, Yuki Sakamoto, Naoya Yoshida, Hideo Baba

Annals of Gastroenterological Surgery.2022; 6(1): 83. CrossRef

The Characteristics of Tumor Microenvironment in Triple Negative Breast Cancer

Cancer Management and Research.2022; Volume 14: 1. CrossRef

Predictive and Prognostic Role of Peripheral Blood T-Cell Subsets in Triple-Negative Breast Cancer

Meng Li, Junnan Xu, Cui Jiang, Jingyan Zhang, Tao Sun

PD-L1 expression in breast invasive ductal carcinoma with incomplete pathological response to neoadjuvant chemotherapy

Ahmad Alhesa, Heyam Awad, Sarah Bloukh, Mahmoud Al-Balas, Mohammed El-Sadoni, Duaa Qattan, Bilal Azab, Tareq Saleh

International Journal of Immunopathology and Pharmacology.2022; 36: 039463202210784. CrossRef

Circulating proteins as predictive and prognostic biomarkers in breast cancer

Hugo Veyssière, Yannick Bidet, Frederique Penault-Llorca, Nina Radosevic-Robin, Xavier Durando

Targeting the antigen processing and presentation pathway to overcome resistance to immune checkpoint therapy

Silvia D’Amico, Patrizia Tempora, Ombretta Melaiu, Valeria Lucarini, Loredana Cifaldi, Franco Locatelli, Doriana Fruci

Programmed death-ligand 1 (PD-L1) expression predicts response to neoadjuvant chemotherapy in triple-negative breast cancer: a systematic review and meta-analysis

Hamdy A. Azim, Kyrillus S. Shohdy, Hagar Elghazawy, Monica M. Salib, Doaa Almeldin, Loay Kassem

Determining Factors in the Therapeutic Success of Checkpoint Immunotherapies against PD-L1 in Breast Cancer: A Focus on Epithelial-Mesenchymal Transition Activation

Mariana Segovia-Mendoza, Susana Romero-Garcia, Cristina Lemini, Heriberto Prado-Garcia, francesca bianchi

Journal of Immunology Research.2021; 2021: 1. CrossRef

Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Sandeep K. Singhal, Jung S. Byun, Samson Park, Tingfen Yan, Ryan Yancey, Ambar Caban, Sara Gil Hernandez, Stephen M. Hewitt, Heike Boisvert, Stephanie Hennek, Mark Bobrow, Md Shakir Uddin Ahmed, Jason White, Clayton Yates, Andrew Aukerman, Rami Vanguri, R

Relationship Between the Neutrophil to Lymphocyte Ratio, Stromal Tumor-infiltrating Lymphocytes, and the Prognosis and Response to Neoadjuvant Chemotherapy in Triple-negative Breast Cancer

Jian Pang, Haiyan Zhou, Xue Dong, Shouman Wang, Zhi Xiao

Immune cell composition and functional marker dynamics from multiplexed immunohistochemistry to predict response to neoadjuvant chemotherapy in the WSG-ADAPT-TN trial

Monika Graeser, Friedrich Feuerhake, Oleg Gluz, Valery Volk, Michael Hauptmann, Katarzyna Jozwiak, Matthias Christgen, Sherko Kuemmel, Eva-Maria Grischke, Helmut Forstbauer, Michael Braun, Mathias Warm, John Hackmann, Christoph Uleer, Bahriye Aktas, Claud

Journal for ImmunoTherapy of Cancer.2021; 9(5): e002198. CrossRef

Clinicopathological and prognostic significance of programmed cell death ligand 1 expression in patients diagnosed with breast cancer: meta-analysis

M G Davey, É J Ryan, M S Davey, A J Lowery, N Miller, M J Kerin

British Journal of Surgery.2021; 108(6): 622. CrossRef

INSTIGO Trial: Evaluation of a Plasma Protein Profile as a Predictive Biomarker for Metastatic Relapse of Triple Negative Breast Cancer

Hugo Veyssière, Sejdi Lusho, Ioana Molnar, Myriam Kossai, Maureen Bernadach, Catherine Abrial, Yannick Bidet, Nina Radosevic-Robin, Xavier Durando

Inhibitors of PD-1/PD-L1 and ERK1/2 impede the proliferation of receptor positive and triple-negative breast cancer cell lines

Karen Bräutigam, Elodie Kabore-Wolff, Ahmad Fawzi Hussain, Stephan Polack, Achim Rody, Lars Hanker, Frank Köster

Journal of Cancer Research and Clinical Oncology.2021; 147(10): 2923. CrossRef

Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer: A Retrospective Analysis in the Neoadjuvant Setting

Antonino Grassadonia, Vincenzo Graziano, Laura Iezzi, Patrizia Vici, Maddalena Barba, Laura Pizzuti, Giuseppe Cicero, Eriseld Krasniqi, Marco Mazzotta, Daniele Marinelli, Antonella Amodio, Clara Natoli, Nicola Tinari

Time-Sequencing of the Neutrophil-to-Lymphocyte Ratio to Predict Prognosis of Triple-Negative Breast Cancer

Joo-Heung Kim, Nak-Hoon Son, Jun-Sang Lee, Ji-Eun Mun, Jee-Ye Kim, Hyung-Seok Park, Seho Park, Seung-Il Kim, Byeong-Woo Park

Platelet-to-Lymphocyte Ratio Is Associated With Favorable Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer: A Study on 120 Patients

Sejdi Lusho, Xavier Durando, Marie-Ange Mouret-Reynier, Myriam Kossai, Nathalie Lacrampe, Ioana Molnar, Frederique Penault-Llorca, Nina Radosevic-Robin, Catherine Abrial

Role of neutrophil-to-lymphocyte ratio as a prognostic biomarker in patients with breast cancer receiving neoadjuvant chemotherapy: a meta-analysis

Qiong Zhou, Jie Dong, Qingqing Sun, Nannan Lu, Yueyin Pan, Xinghua Han

Neutrophil to Lymphocyte Ratio after Treatment Completion as a Potential Predictor of Survival in Patients with Triple-Negative Breast Cancer

Kwang-Min Kim, Hyang Suk Choi, Hany Noh, In-Jeong Cho, Seung Taek Lim, Jong-In Lee, Airi Han

Journal of Breast Cancer.2021; 24(5): 443. CrossRef

Tumor Microenvironment Characterization in Breast Cancer Identifies Prognostic and Neoadjuvant Chemotherapy Relevant Signatures

Fei Ji, Jiao-Mei Yuan, Hong-Fei Gao, Ai-Qi Xu, Zheng Yang, Ci-Qiu Yang, Liu-Lu Zhang, Mei Yang, Jie-Qing Li, Teng Zhu, Min-Yi Cheng, Si-Yan Wu, Kun Wang

Frontiers in Molecular Biosciences.2021;[Epub] CrossRef

Neutrophil to Lymphocyte Ratio as Prognostic and Predictive Factor in Breast Cancer Patients: A Systematic Review

A Rosetta Stone for Breast Cancer: Prognostic Value and Dynamic Regulation of Neutrophil in Tumor Microenvironment

Wei Zhang, Yimin Shen, Huanhuan Huang, Sheng Pan, Jingxin Jiang, Wuzhen Chen, Ting Zhang, Chao Zhang, Chao Ni

Perspectives on Triple-Negative Breast Cancer: Current Treatment Strategies, Unmet Needs, and Potential Targets for Future Therapies

Gagan K. Gupta, Amber L. Collier, Dasom Lee, Richard A. Hoefer, Vasilena Zheleva, Lauren L. Siewertsz van Reesema, Angela M. Tang-Tan, Mary L. Guye, David Z. Chang, Janet S. Winston, Billur Samli, Rick J. Jansen, Emanuel F. Petricoin, Matthew P. Goetz, Ha

Prognostic Role and Clinical Significance of Tumor-Infiltrating Lymphocyte (TIL) and Programmed Death Ligand 1 (PD-L1) Expression in Triple-Negative Breast Cancer (TNBC): A Systematic Review and Meta-Analysis Study

Parisa Lotfinejad, Mohammad Asghari Jafarabadi, Mahdi Abdoli Shadbad, Tohid Kazemi, Fariba Pashazadeh, Siamak Sandoghchian Shotorbani, Farhad Jadidi Niaragh, Amir Baghbanzadeh, Nafiseh Vahed, Nicola Silvestris, Behzad Baradaran

Prediction of Late Recurrence and Distant Metastasis in Early-stage Breast Cancer: Overview of Current and Emerging Biomarkers

A. Gouri, B. Benarba, A. Dekaken, H. Aoures, S. Benharkat

Prognostic value of neutrophil‐to‐lymphocyte ratio and platelet‐to‐lymphocyte ratio for breast cancer patients: An updated meta‐analysis of 17079 individuals

Wanying Guo, Xin Lu, Qipeng Liu, Ting Zhang, Peng Li, Weiqiang Qiao, Miao Deng

Prognostic and clinicopathological value of PD-L1 expression in primary breast cancer: a meta-analysis

Breast Cancer Research and Treatment.2019; 178(1): 17. CrossRef

Comparison of Preoperative Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Bladder Cancer Patients Undergoing Radical Cystectomy

BioMed Research International.2019; 2019: 1. CrossRef

Immunotherapy in HER2-positive breast cancer: state of the art and future perspectives

E. Krasniqi, G. Barchiesi, L. Pizzuti, M. Mazzotta, A. Venuti, M. Maugeri-Saccà, G. Sanguineti, G. Massimiani, D. Sergi, S. Carpano, P. Marchetti, S. Tomao, T. Gamucci, R. De Maria, F. Tomao, C. Natoli, N. Tinari, G. Ciliberto, M. Barba, P. Vici

Journal of Hematology & Oncology.2019;[Epub] CrossRef

Prognostic Implications of PD-L1 Expression in Breast Cancer: Systematic Review and Meta-analysis of Immunohistochemistry and Pooled Analysis of Transcriptomic Data

Alexios Matikas, Ioannis Zerdes, John Lövrot, François Richard, Christos Sotiriou, Jonas Bergh, Antonios Valachis, Theodoros Foukakis

Clinical Cancer Research.2019; 25(18): 5717. CrossRef