Cancer Research and Treatment

Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway

Wanhui Wei, Yuanyuan Lu, Qian Hu, Jinwen Yin, Youwei Wang, Heng Zhang, Qiu Zhao, Lan Liu

Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy

Shutong Li, Aoxue Wang, Yongya Wu, Shengyuan He, Wen Shuai, Min Zhao, Yumeng Zhu, Xiuying Hu, Yubin Luo, Guan Wang

Immunological Reviews.2024; 321(1): 300. CrossRef

Impact of TP53‐induced glycolysis and apoptosis regulator on malignant activity and resistance to ferroptosis in intrahepatic cholangiocarcinoma

Katsuya Toshida, Shinji Itoh, Norifumi Iseda, Takuma Izumi, Shohei Yoshiya, Takeo Toshima, Mizuki Ninomiya, Takeshi Iwasaki, Yoshinao Oda, Tomoharu Yoshizumi

Heteronemin promotes iron-dependent cell death in pancreatic cancer

Gizem Kaftan, Mümin Alper Erdoğan, Mohamed El-Shazly, Mei-Chin Lu, Shou-Ping Shih, Hung-Yu Lin, Luciano Saso, Güliz Armagan

Naunyn-Schmiedeberg's Archives of Pharmacology.2024; 397(3): 1865. CrossRef

Yi-qi-hua-yu-jie-du decoction induces ferroptosis in cisplatin-resistant gastric cancer via the AKT/GSK3β/NRF2/GPX4 axis

Wenjie Huang, Fang Wen, Peipei Yang, Ye Li, Qiurong Li, Peng Shu

Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15

Sheng‐Fan Wang, Yuh‐Lih Chang, Ting‐Yu Liu, Kuo‐Hung Huang, Wen‐Liang Fang, Anna Fen‐Yau Li, Tien‐Shun Yeh, Giun‐Yi Hung, Hsin‐Chen Lee

Current and Potential Roles of Ferroptosis in Bladder Cancer

Wen-xin An, Radheshyam Gupta, Kun Zhai, Ya-ru Wang, Wan-hai Xu, Yan Cui

Current Medical Science.2024; 44(1): 51. CrossRef

BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1

Yizhi Cao, Xuelong Wang, Yang Liu, Pengyi Liu, Jiejie Qin, Youwei Zhu, Shuyu Zhai, Yongsheng Jiang, Yihao Liu, Lijie Han, Jiaxin Luo, Ronghao Zhang, Minmin Shi, Liwen Wang, Xiaomei Tang, Meilin Xue, Jia Liu, Weishen Wang, Chenlei Wen, Xiaxing Deng, Chengh

Ferroptosis and its modulators: A raising target for cancer and Alzheimer’s disease

Gourav Singh, Prashant Kesharwani, Gireesh Kumar Singh, Saroj Kumar, Anjaneyulu Putta, Gyan Modi

Bioorganic & Medicinal Chemistry.2024; 98: 117564. CrossRef

The application of nanoparticles based on ferroptosis in cancer therapy

Yifei Li, Chen Wei, Jianqin Yan, Fashun Li, Bohan Chen, Yong Sun, Kui Luo, Bin He, Yan Liang

Journal of Materials Chemistry B.2024; 12(2): 413. CrossRef

Stability-Enhanced Cisplatin Gold Nanoparticles as Therapeutic Anticancer Agents

Tae Joon Cho, Vytas Reipa, Justin M. Gorham, John M. Pettibone, Alessandro Tona, Aaron Johnston-Peck, Jingyu Liu, Bryant C. Nelson, Vincent A. Hackley

ACS Applied Nano Materials.2024; 7(1): 836. CrossRef

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

Anqi Ge, Qi He, Da Zhao, Yuwei Li, Junpeng Chen, Ying Deng, Wang Xiang, Hongqiao Fan, Shiting Wu, Yan Li, Lifang Liu, Yue Wang

Journal of Cellular and Molecular Medicine.2024;[Epub] CrossRef

Iron accumulation and lipid peroxidation: implication of ferroptosis in hepatocellular carcinoma

Xiaodong Li, Fanguang Meng, Hankang Wang, Liwei Sun, Shulin Chang, Guijie Li, Feng Chen

Crosstalk between ferroptosis and cuproptosis: From mechanism to potential clinical application

Biomedicine & Pharmacotherapy.2024; 171: 116115. CrossRef

A risk model based on 10 ferroptosis regulators and markers established by LASSO-regularized linear Cox regression has a good prognostic value for ovarian cancer patients

Kai Hou, Lin Liu, Zhi-Hui Fang, Wei-Xing Zong, Daqiang Sun, Zhigang Guo, Lu Cao

Archives of Toxicology.2024; 98(3): 709. CrossRef

Exploring the Use of Intracellular Chelation and Non-Iron Metals to Program Ferroptosis for Anticancer Application

Oscar Claudio-Ares, Jeileen Luciano-Rodríguez, Yolmarie L. Del Valle-González, Selene L. Schiavone-Chamorro, Alex J. Pastor, Javier O. Rivera-Reyes, Carmen L. Metzler, Lizandra M. Domínguez-Orona, Brenda Lee Vargas-Pérez, Rachid Skouta, Arthur D. Tinoco

Ferroptosis: a dual-edged sword in tumour growth

Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity

Yihong Wei, Wancheng Liu, Ruiqing Wang, Yuhong Chen, Jinting Liu, Xiaodong Guo, Can Can, Xinyu Yang, Dongmei Wang, Xiang Hu, Daoxin Ma

Free Radical Biology and Medicine.2024; 213: 36. CrossRef

Programmed cell death in tumor immunity: mechanistic insights and clinical implications

Extracellular vesicle-mediated ferroptosis, pyroptosis, and necroptosis: potential clinical applications in cancer therapy

Yi-Chi Yang, Qian Jiang, Ke-Ping Yang, Lingzhi Wang, Gautam Sethi, Zhaowu Ma

Modulating ferroptosis sensitivity: environmental and cellular targets within the tumor microenvironment

Yuze Hua, Sen Yang, Yalu Zhang, Jiayi Li, Mengyi Wang, Palashate Yeerkenbieke, Quan Liao, Qiaofei Liu

Journal of Experimental & Clinical Cancer Research.2024;[Epub] CrossRef

Chemo-photothermal nanoplatform with diselenide as the key for ferroptosis in colorectal cancer

Kaili Deng, Hailong Tian, Tingting Zhang, Yajie Gao, Edouard C. Nice, Canhua Huang, Na Xie, Guoliang Ye, Yuping Zhou

Journal of Controlled Release.2024; 366: 684. CrossRef

Ferroptosis in head and neck squamous cell carcinoma: from pathogenesis to treatment

Lysine acetyltransferase KAT2A modulates ferroptosis during colorectal cancer development

Zhenye Xu, Xiaoyan Wang, Ping Yu, Yong Zhang, Liang Huang, Enqiang Mao, Yi Han

Scandinavian Journal of Gastroenterology.2024; 59(4): 437. CrossRef

Recent Progress in Ferroptosis Induced Tumor Cell Death by Anti‐tumor Metallic complexes

Yong‐Chang Zhou, Tian‐Kun Zhao, Si‐Man Tao, Peng Wang, Yi‐Chen Guan, Ke‐Pei Yang, Sheng‐Qiang Chen, Xiu‐Ying Pu

Chemistry – An Asian Journal.2024;[Epub] CrossRef

Ferroptosis-Based Therapeutic Strategies toward Precision Medicine for Cancer

Journal of Medicinal Chemistry.2024; 67(4): 2238. CrossRef

Novel application of the ferroptosis-related genes risk model associated with disulfidptosis in hepatocellular carcinoma prognosis and immune infiltration

Jiayan Wei, Jinsong Wang, Xinyi Chen, Li Zhang, Min Peng

Edaravone-loaded poly(amino acid) nanogel inhibits ferroptosis for neuroprotection in cerebral ischemia injury

Yunhan Zhang, Zhulin Zou, Shuang Liu, Fangfang Chen, Minglu Li, Haoyang Zou, Haiyan Liu, Jianxun Ding

Asian Journal of Pharmaceutical Sciences.2024; 19(2): 100886. CrossRef

A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer

Xiaomin Shen, Yue Peng, Haixia Zhou, Xiaoxia Ye, Zhong Han, Xiangchao Shi

Journal of Inorganic Biochemistry.2024; 253: 112502. CrossRef

A Smooth Muscle Cell-Based Ferroptosis Model to Evaluate Iron-Chelating Molecules for Cardiovascular Disease Treatment

Sarah El Hajj, Laetitia Canabady-Rochelle, Isabelle Fries-Raeth, Caroline Gaucher

Current Issues in Molecular Biology.2024; 46(2): 1348. CrossRef

DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy

Yuwei Yang, Yuanfang Chen, Haikang Tang, Ziqi Zhang, Xiaoliang Zhou, Wenqing Xu

Biomedicine & Pharmacotherapy.2024; 172: 116227. CrossRef

Iron Oxide Nanoparticles Carrying microRNA-124 Promote Ferroptosis in Treatment of Prostate Cancer

Min Liu, Chuanbing Xu, Huichao Dong, Dongshen Jia, Dongfang Hao, Ruozen Rong, Yao Peng

Journal of Biomedical Nanotechnology.2024; 20(2): 224. CrossRef

Targeting LGR4–Wnt activates ferroptosis and reverses drug resistance in colorectal cancer

Recent research progress based on ferroptosis-related signaling pathways and the tumor microenvironment on it effects

Shijing Yu, Lingwu Tong, Jiangwen Shen, Chenglei Li, Yongshan Hu, Keke Feng, Jingwei Shao

European Journal of Medicinal Chemistry.2024; 269: 116290. CrossRef

TRAIL predisposes non-small cell lung cancer to ferroptosis by regulating ASK-1/JNK1 pathway

Xiaofang Liu, Huiqian Deng, Mi Huang, Wei Zhou, Yilin Yang

G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis

Jiaping Chen, Rong Zhao, Yangwei Wang, Han Xiao, Wei Lin, Mingxin Diao, Shiwen He, Peiyuan Mei, Yongde Liao

Cisplatin Nephrotoxicity Is Critically Mediated by the Availability of BECLIN1

Tillmann Bork, Camila Hernando-Erhard, Wei Liang, Zhejia Tian, Kosuke Yamahara, Tobias B. Huber

International Journal of Molecular Sciences.2024; 25(5): 2560. CrossRef

Ailanthone induces autophagy and ferroptosis in non‑small cell lung cancer Lewis cells

Hongbin Yang, Xiaotong Zhang, Yanjie Lu, Xin Wang, Zhengxin Zhang, Hailan Xu, Fan Li, Qianhui Chen, Yiying Bai, Xinyu Bai, Li Zhang, Lei Liu

Molecular and Clinical Oncology.2024;[Epub] CrossRef

Ferroptosis in lung cancer: dual role, multi-level regulation, and new therapeutic strategies

Curcumin activates the JNK signaling pathway to promote ferroptosis in colon cancer cells

Chemical Biology & Drug Design.2024;[Epub] CrossRef

Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies

Qian Zhou, Yu Meng, Daishi Li, Lei Yao, Jiayuan Le, Yihuang Liu, Yuming Sun, Furong Zeng, Xiang Chen, Guangtong Deng

Signal Transduction and Targeted Therapy.2024;[Epub] CrossRef

AURKA knockdown inhibits esophageal squamous cell carcinoma progression through ferroptosis

Yuan Mi, Liying Chen, Cong Wang, Yuxin Miao, Chuntao Song, Jie Su, Lei Wang

Harnessing ferroptosis for enhanced sarcoma treatment: mechanisms, progress and prospects

Jing Zeng, Xianghong Zhang, Zhengjun Lin, Yu Zhang, Jing Yang, Pengcheng Dou, Tang Liu

Experimental Hematology & Oncology.2024;[Epub] CrossRef

Emerging mechanisms of ferroptosis and its implications in lung cancer

Chinese Medical Journal.2024; 137(7): 818. CrossRef

Role of ferroptosis and ferroptosis-related long non'coding RNA in breast cancer

Shasha Xiang, Wen Yan, Xing Ren, Jianbo Feng, Xuyu Zu

Cellular & Molecular Biology Letters.2024;[Epub] CrossRef

Meningioma achieves malignancy and erastin-induced ferroptosis resistance through FOXM1-AURKA-NRF2 axis

Yangfan Ye, Lei Xu, Liuchao Zhang, Pengzhan Zhao, Wanzhi Cai, Guoqiang Fu, Tian Wang, Zeqiang Tao, Wenqian Shi, Wei Gu, Jingming Hu, Guangyao Yuan, Yutian Wei, Ke Xu, Zhongyuan Bao, Honglu Chao, Ning Liu, Lin Zhao, Yiming Tu, Jing Ji

Esculin induces endoplasmic reticulum stress and drives apoptosis and ferroptosis in colorectal cancer via PERK regulating eIF2α/CHOP and Nrf2/HO-1 cascades

Xiaoke Ji, Zongpin Chen, Weifan Lin, Qifang Wu, Yu Wu, Yan Hong, Haibin Tong, Changxiong Wang, Ya Zhang

Journal of Ethnopharmacology.2024; 328: 118139. CrossRef

A multi-mode Rhein-based nano-platform synergizing ferrotherapy/chemotherapy-induced immunotherapy for enhanced tumor therapy

Xiaokang Zhu, Li Xie, Jinming Tian, Yang Jiang, Erqun Song, Yang Song

Synergistic eradicating impact of 5-fluouracil with FeO nanoparticles-diethyldithiocarbamate in colon cancer spheroids

Mutational signature-based identification of DNA repair deficient gastroesophageal adenocarcinomas for therapeutic targeting

Aurel Prosz, Pranshu Sahgal, Brandon M. Huffman, Zsofia Sztupinszki, Clare X. Morris, David Chen, Judit Börcsök, Miklos Diossy, Viktoria Tisza, Sandor Spisak, Pornlada Likasitwatanakul, Orsolya Rusz, Istvan Csabai, Michael Cecchini, Yasmine Baca, Andrew E

Targeting ferroptosis for leukemia therapy: exploring novel strategies from its mechanisms and role in leukemia based on nanotechnology

Muhammad Hossein Ashoub, Razieh Razavi, Kamran Heydaryan, Masoud Salavati-Niasari, Mahnaz Amiri

European Journal of Medical Research.2024;[Epub] CrossRef

LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis

Nan Cao, Fangmei Zhang, Jiang Yin, Jianlei Zhang, Xiqing Bian, Guopei Zheng, Nan Li, Ying Lin, Liyun Luo

Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression

Rumeng Pan, Rongli Wang, Feiyan Cheng, Lihui Wang, Zhiwei Cui, Jing She, Xinyuan Yang

Reproductive Biology and Endocrinology.2024;[Epub] CrossRef

Deciphering Ferroptosis: From Molecular Pathways to Machine Learning-Guided Therapeutic Innovation

Megha Mete, Amiya Ojha, Priyanka Dhar, Deeplina Das

FSP1-mediated ferroptosis in cancer: from mechanisms to therapeutic applications

Ran Gao, Jinge Wang, Jingjing Huang, Tong Wang, Lingfeng Guo, Wenlu Liu, Jialu Guan, Desen Liang, Qinghui Meng, Huayang Pan

Recent advancements in nanomaterial-mediated ferroptosis-induced cancer therapy: Importance of molecular dynamics and novel strategies

Namdev Dhas, Ritu Kudarha, Ruchi Tiwari, Gaurav Tiwari, Neha Garg, Praveen Kumar, Sanjay Kulkarni, Jahnavi Kulkarni, Soji Soman, Aswathi R. Hegde, Jayvadan Patel, Atul Garkal, Anam Sami, Deepanjan Datta, Viola Colaco, Tejal Mehta, Lalitkumar Vora, Sriniva

Unlocking ferroptosis in prostate cancer — the road to novel therapies and imaging markers

Pham Hong Anh Cao, Abishai Dominic, Fabiola Ester Lujan, Sanjanaa Senthilkumar, Pratip K. Bhattacharya, Daniel E. Frigo, Elavarasan Subramani

Disruption of lipid metabolism to induce ferroptosis using multifunctional fibrate-Pt(iv) prodrugs for cancer treatment

Peng Sun, Jia-Qian Wang, Qiang Xie, Xuan-Lin Ren, Xin Qiao, Jing-Yuan Xu

Inorganic Chemistry Frontiers.2024;[Epub] CrossRef

Cancer-associated fibroblasts secrete FGF5 to inhibit ferroptosis to decrease cisplatin sensitivity in nasopharyngeal carcinoma through binding to FGFR2

Feng Liu, Ling Tang, Huai Liu, Yanzhu Chen, Tengfei Xiao, Wangning Gu, Hongmin Yang, Hui Wang, Pan Chen

Ferroptosis-related lncRNA NRAV affects the prognosis of hepatocellular carcinoma via the miR-375-3P/SLC7A11 axis

Ke Zong, Caifeng Lin, Kai Luo, Yilei Deng, Hongfei Wang, Jianfei Hu, Shi Chen, Renfeng Li

Oleanolic Acid Acetate Alleviates Cisplatin-Induced Nephrotoxicity via Inhibition of Apoptosis and Necroptosis In Vitro and In Vivo

Bori Lee, Yeon-Yong Kim, Seungwon Jeong, Seung Woong Lee, Seung-Jae Lee, Mun-Chual Rho, Sang-Hyun Kim, Soyoung Lee

Ferroptosis is an effective strategy for cancer therapy

Afrasyab Khan, Yu Huo, Yilei Guo, Juanjuan Shi, Yongzhong Hou

Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer

Xin Jin, Wenke Jin, Linlin Tong, Jia Zhao, Lan Zhang, Na Lin

Overexpressed transferrin receptor implied poor prognosis and relapse in gastrointestinal stromal tumors

Chun Zhuang, Xiaoqi Li, Linxi Yang, Xinli Ma, Yanying Shen, Chen Huang, Tao Pan, Jianzhi Cui, Bo Ni, Ming Wang

Nitroimidazoles Part 10. Synthesis, crystal structure, molecular docking, and anticancer evaluation of 4-nitroimidazole derivatives combined with piperazine moiety

Yaseen A. Al-Soud, Sadeekah O. W. Saber, Amneh Shtaiwi, Sondos O. Alsawakhneh, Kafa’ A. S. Alhelal, Qusay F. A. Salman, Luay Abu-Qatouseh, Monther A. Khanfar, Raed A. Al-Qawasmeh

Zeitschrift für Naturforschung C.2023; 78(3-4): 93. CrossRef

The role of ferroptosis in prostate cancer: a novel therapeutic strategy

Prostate Cancer and Prostatic Diseases.2023; 26(1): 25. CrossRef

Mechanistic Approach for Protective Effect of ARA290, a Specific Ligand for the Erythropoietin/CD131 Heteroreceptor, against Cisplatin-Induced Nephrotoxicity, the Involvement of Apoptosis and Inflammation Pathways

Nasrin Ghassemi-Barghi, Zeynab Ehsanfar, Omid Mohammadrezakhani, Sorour Ashari, Shamim Ghiabi, Zahra Bayrami

Ferroptosis in hepatocellular carcinoma: mechanisms and targeted therapy

Amir Ajoolabady, Daolin Tang, Guido Kroemer, Jun Ren

British Journal of Cancer.2023; 128(2): 190. CrossRef

Metal complexes induced ferroptosis for anticancer therapy

Arenobufagin causes ferroptosis in human gastric cancer cells by increasing rev-erbα expression

Ke Chen, Angling Li, Jian Wang, Dongchang Li, Xiaoshan Wang, Chengwei Liu, Zhengguang Wang

Journal of Traditional and Complementary Medicine.2023; 13(1): 72. CrossRef

Research trends in ferroptosis since the origin of the concept: A bibliometric analysis

Huimin Deng, Juan Wei, Keting Min, Hao Yang, Sheng Wang, Zhuoran Xiao, Meiyun Liu, Li Zheng, Huanping Zhou, Yuanli Chen, Wanli Zhu, Quanfu Li, Xin Lv

Clinical and Experimental Pharmacology and Physiology.2023; 50(2): 149. CrossRef

Targeting lipid metabolism for ferroptotic cancer therapy

Minhua Luo, Jiajing Yan, Xinyu Hu, Haolong Li, Hongsheng Li, Quentin Liu, Yibing Chen, Zhengzhi Zou

Metal-free polymer nano-photosensitizer actuates ferroptosis in starved cancer

Dapeng Chen, Chen Liang, Xinyu Qu, Tian Zhang, Xiaozhou Mou, Yu Cai, Wenjun Wang, Jinjun Shao, Xiaochen Dong

Targeting ferroptosis: Paving new roads for drug design and discovery

Yilin Gu, Yizhe Li, Jiaxing Wang, Lele Zhang, Jifa Zhang, Yuxi Wang

European Journal of Medicinal Chemistry.2023; 247: 115015. CrossRef

Ferroptosis: a potential therapeutic target for Alzheimer’s disease

Reviews in the Neurosciences.2023; 34(5): 573. CrossRef

Mechanism and application of ferroptosis in colorectal cancer

Biomedicine & Pharmacotherapy.2023; 158: 114102. CrossRef

Overcoming cancer chemotherapy resistance by the induction of ferroptosis

Yumin Wang, Xiaorui Wu, Zhao Ren, Yulin Li, Wailong Zou, Jichao Chen, Hongquan Wang

Drug Resistance Updates.2023; 66: 100916. CrossRef

Amplified Fenton-Based Oxidative Stress Utilizing Ultraviolet Upconversion Luminescence-Fueled Nanoreactors for Apoptosis-Strengthened Ferroptosis Anticancer Therapy

Nguyen Thi Nguyen, Juho Kim, Xuan Thien Le, Woo Tak Lee, Eun Seong Lee, Kyung Taek Oh, Han-Gon Choi, Yu Seok Youn

NaErF4-Based Nanocarrier for Enhanced Ferroptosis Therapy of Cancer

Jin-Yang Liu, Na Liu, Yue Wu, Xiao-Min Ning, Wen-Chao Zhang, Jing Qian

ACS Applied Nano Materials.2023; 6(1): 270. CrossRef

Liposomes embedded with PEGylated iron oxide nanoparticles enable ferroptosis and combination therapy in cancer

Yang Liu, Xuebo Quan, Jie Li, Jiawei Huo, Xing Li, Zhongpu Zhao, Shumu Li, Jing Wan, Jiao Li, Shuai Liu, Tao Wang, Xing Zhang, Bo Guan, Rui Wen, Zhenwen Zhao, Chunru Wang, Chunli Bai

Review and Chemoinformatic Analysis of Ferroptosis Modulators with a Focus on Natural Plant Products

Mechanism of ferroptosis in traditional chinese medicine for clinical treatment: A review

Jiajiao Liu, Guanyin Jiang, Pengfei He, Xing Du, Zhenming Hu, Fuxiang Li

Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis

Xing-Qiang Dong, Li-Kai Chu, Xu Cao, Qian-Wei Xiong, Yi-Ming Mao, Ching-Hsien Chen, Yun-Li Bi, Jun Liu, Xiang-Ming Yan

Review of ferroptosis in colorectal cancer: Friends or foes?

Zheng Wu, Ze-Xuan Fang, Yan-Yu Hou, Bing-Xuan Wu, Yu Deng, Hua-Tao Wu, Jing Liu

World Journal of Gastroenterology.2023; 29(3): 469. CrossRef

Ferroptosis as a therapeutic target for inflammation-related intestinal diseases

Crosstalk between microwave ablation and ferroptosis: The next hot topic?

Lu Yu, Min Cheng, Jie Liu, Xin Ye, Zhigang Wei, Jiamei Xu, Qi Xie, Jing Liang

Progress in the study of ferroptosis in cancer treatment: State-of-the-Art

Chemico-Biological Interactions.2023; 371: 110348. CrossRef

RNA methylation and cellular response to oxidative stress-promoting anticancer agents

Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy

Wenhua Wang, Wenhao Wang, Shiwei Jin, Fangqin Fu, Zhengwei Huang, Ying Huang, Chuanbin Wu, Xin Pan

Chemical Engineering Journal.2023; 458: 141487. CrossRef

Iron as a therapeutic target in chronic liver disease

Elias Kouroumalis, Ioannis Tsomidis, Argyro Voumvouraki

World Journal of Gastroenterology.2023; 29(4): 616. CrossRef

Ferroptosis in colorectal cancer: a future target?

Hong Yan, Ronan Talty, Oladimeji Aladelokun, Marcus Bosenberg, Caroline H. Johnson

British Journal of Cancer.2023; 128(8): 1439. CrossRef

Targeting critical pathways in ferroptosis and enhancing antitumor therapy of Platinum drugs for colorectal cancer

Gang Wang, Jun-Jie Wang, Zhu Zhi-Min, Xiao-Na Xu, Feng Shi, Xing-Li Fu

Science Progress.2023; 106(1): 003685042211471. CrossRef

Solute Carrier Family 7 Member 11 (SLC7A11) is a Potential Prognostic Biomarker in Uterine Corpus Endometrial Carcinoma

International Journal of General Medicine.2023; Volume 16: 481. CrossRef

Overexpression of PRDX2 in Adipose-Derived Mesenchymal Stem Cells Enhances the Therapeutic Effect in a Neurogenic Erectile Dysfunction Rat Model by Inhibiting Ferroptosis

Peng Chen, Zehong Chen, Jiancheng Zhai, Wende Yang, Hongbo Wei, Víctor M. Mendoza-Núñez

Oxidative Medicine and Cellular Longevity.2023; 2023: 1. CrossRef

Ferroptosis: challenges and opportunities for nanomaterials in cancer therapy

Qiaolin Liu, Yuliang Zhao, Huige Zhou, Chunying Chen

miR-29a-5p modulates ferroptosis by targeting ferritin heavy chain FTH1 in prostate cancer

Biochemical and Biophysical Research Communications.2023; 652: 6. CrossRef

Reactive Oxygen Species and Ferroptosis at the Nexus of Inflammation and Colon Cancer

Antioxidants & Redox Signaling.2023; 39(7-9): 551. CrossRef

Cell death, therapeutics, and the immune response in cancer

Ferroptosis-related metabolic mechanism and nanoparticulate anticancer drug delivery systems based on ferroptosis

Saudi Pharmaceutical Journal.2023; 31(4): 554. CrossRef

Molecular Mechanisms of Nemorosone-Induced Ferroptosis in Cancer Cells

Roberto Fernández-Acosta, Behrouz Hassannia, Jurgen Caroen, Bartosz Wiernicki, Daniel Alvarez-Alminaque, Bruno Verstraeten, Johan Van der Eycken, Peter Vandenabeele, Tom Vanden Berghe, Gilberto L. Pardo-Andreu

Ferroptosis As Ultimate Target of Cancer Therapy

Antioxidants & Redox Signaling.2023; 39(1-3): 206. CrossRef

Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer

Federica Maccarinelli, Daniela Coltrini, Silvia Mussi, Mattia Bugatti, Marta Turati, Paola Chiodelli, Arianna Giacomini, Floriana De Cillis, Nadia Cattane, Annamaria Cattaneo, Alessia Ligresti, Michela Asperti, Maura Poli, William Vermi, Marco Presta, Rob

Identification of cuproptosis hub genes contributing to the immune microenvironment in ulcerative colitis using bioinformatic analysis and experimental verification

Cejun Yang, Wendi Wang, Sang Li, Zhengkang Qiao, Xiaoqian Ma, Min Yang, Juan Zhang, Lu Cao, Shanhu Yao, Zhe Yang, Wei Wang

The unfolding story of dying tumor cells during cancer treatment

Engineered exosomes from different sources for cancer-targeted therapy

Menghui Zhang, Shengyun Hu, Lin Liu, Pengyuan Dang, Yang Liu, Zhenqiang Sun, Bingbing Qiao, Chengzeng Wang

Signal Transduction and Targeted Therapy.2023;[Epub] CrossRef

Development and validation of a combined hypoxia and ferroptosis prognostic signature for breast cancer

Jianxin Zhong, Xi Shen, Junjie Zhou, Heping Yu, Birong Wang, Jianbin Sun, Jing Wang, Feng Liu

Mechanism of ferroptosis in a rat model of premature ovarian insufficiency induced by cisplatin

Rong Du, Xi Cheng, Jingjing Ji, Yang Lu, Yuanyuan Xie, Weina Wang, Yanhua Xu, Yuquan Zhang

An anticancer Ti(IV) complex increases mitochondrial reactive oxygen species levels in relation with hypoxia and endoplasmic-reticulum stress: A distinct non DNA-related mechanism

Journal of Inorganic Biochemistry.2023; 243: 112197. CrossRef

Ferroptosis: Mechanism and potential applications in cervical cancer

Frontiers in Molecular Biosciences.2023;[Epub] CrossRef

Ferroptosis in gastrointestinal cancer: from mechanisms to implications

Ferroptosis Detection: From Approaches to Applications

Fantian Zeng, Sureya Nijiati, Longguang Tang, Jinmin Ye, Zijian Zhou, Xiaoyuan Chen

Angewandte Chemie International Edition.2023;[Epub] CrossRef

Ferroptosis Detection: From Approaches to Applications

Fantian Zeng, Sureya Nijiati, Longguang Tang, Jinmin Ye, Zijian Zhou, Xiaoyuan Chen

The Regulation Role of Ferroptosis Mechanism of Anti-Cancer Drugs and Noncoding RNAs

Mine Ensoy, Zehra Sena Bumin, Huda Abdirizak Jama, Demet Cansaran-Duman

Current Medicinal Chemistry.2023; 30(14): 1638. CrossRef

Comprehensive characterization of ferroptosis in hepatocellular carcinoma revealing the association with prognosis and tumor immune microenvironment

Jingjuan Zhu, Xiao Xu, Man Jiang, Fangfang Yang, Yingying Mei, Xiaochun Zhang

Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy

Nan Xing, Qinyun Du, Sa Guo, Gelin Xiang, Yi Zhang, Xianli Meng, Li Xiang, Shaohui Wang

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling

Solveigh C. Koeberle, Anna P. Kipp, Hermann Stuppner, Andreas Koeberle

Medicinal Research Reviews.2023; 43(3): 614. CrossRef

Implication of Ferroptosis in Cholangiocarcinoma: A Potential Future Target?

Cancer Management and Research.2023; Volume 15: 335. CrossRef

A review of nemorosone: Chemistry and biological properties

Osmany Cuesta-Rubio, Lianet Monzote, Roberto Fernández-Acosta, Gilberto Lázaro Pardo-Andreu, Luca Rastrelli

Ferroptosis landscape in prostate cancer from molecular and metabolic perspective

Jiaming Liang, Yihao Liao, Pu Wang, Kun Yang, Youzhi Wang, Keke Wang, Boqiang Zhong, Diansheng Zhou, Qian Cao, Junbo Li, Yang Zhao, Ning Jiang

Gallium maltolate shows synergism with cisplatin and activates nucleolar stress and ferroptosis in human breast carcinoma cells

Chieh-Hsin Chen, Yi-Ming Huang, Louis Grillet, Yu-Chen Hsieh, Ya-Wen Yang, Kai-Yin Lo

Ferroptosis regulates key signaling pathways in gastrointestinal tumors: Underlying mechanisms and therapeutic strategies

Ravichandiran Rabitha, Sethuraman Shivani, Yahya Showket, Ganapasam Sudhandiran

World Journal of Gastroenterology.2023; 29(16): 2433. CrossRef

Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells

Yingchao Wu, Dajin Pi, Shuyao Zhou, Zhongjia Yi, Yangyang Dong, Wuhong Wang, Huan Ye, Yiliu Chen, Qian Zuo, Mingzi Ouyang

Acta Biochimica et Biophysica Sinica.2023; 55(4): 587. CrossRef

Modulation of Ferroptosis by microRNAs in Human Cancer

Irena Velkova, Martina Pasino, Zumama Khalid, Paola Menichini, Emanuele Martorana, Alberto Izzotti, Alessandra Pulliero

Journal of Personalized Medicine.2023; 13(5): 719. CrossRef

Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin

Chenyuan Li, Ziqi He, Feng Yao, Shichong Liao, Kai Sun, Shengrong Sun, Zhiyu Li, Zhong Wang

PCBP1 protects bladder cancer cells from mitochondria injury and ferroptosis by inducing LACTB mRNA degradation

Yang Luo, Yunli Zhang, Shiyu Pang, Jingxian Min, Tao Wang, Dali Wu, Chun Lin, Zebin Xiao, Qi Xiang, Qing Li, Lili Ma

Molecular Carcinogenesis.2023; 62(7): 907. CrossRef

Recent Advances of Platinum‐Based Anticancer Complexes in Combinational Multimodal Therapy

Tianyuan Zhong, Jie Yu, Yong Pan, Ning Zhang, Yanxin Qi, Yubin Huang

Advanced Healthcare Materials.2023;[Epub] CrossRef

SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex

Ping Huang, Han Zhao, Xiafang Pan, Jinying Li, Wentian Pan, Hua Dai, Jia Wang, Chunhua Xia, Fanglan Liu

Biochemical Pharmacology.2023; 213: 115592. CrossRef

AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

Kaitlyn M. Cahuzac, Abigail Lubin, Kaitlyn Bosch, Nicole Stokes, Sarah Mense Shoenfeld, Royce Zhou, Haddy Lemon, John Asara, Ramon E. Parsons

CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer

Xiaoqian Zhang, Xiaocui Zheng, Xiang Ying, Weiwei Xie, Yujia Yin, Xipeng Wang

Journal of Translational Medicine.2023;[Epub] CrossRef

Expression of Ferredoxin1 in cisplatin‑resistant ovarian cancer cells confers their resistance against ferroptosis induced by cisplatin

Ryosuke Takahashi, Koki Kamizaki, Keitaro Yamanaka, Yoshito Terai, Yasuhiro Minami

Exosomal miR-17–92 derived from human mesenchymal stem cells promotes wound healing by enhancing angiogenesis and inhibiting endothelial cell ferroptosis

Wenbo Nie, Xuemiao Huang, Lijing Zhao, Taiwei Wang, Dan Zhang, Tianxin Xu, Lin Du, Yuxiang Li, Weiyuan Zhang, Fengjun Xiao, Lisheng Wang

Progress in the Mechanism of the Effect of Fe3O4 Nanomaterials on Ferroptosis in Tumor Cells

Donafenib and GSK‐J4 Synergistically Induce Ferroptosis in Liver Cancer by Upregulating HMOX1 Expression

Chenyang Zheng, Bo Zhang, Yunyun Li, Kejia Liu, Wei Wei, Shuhang Liang, Hongrui Guo, Kun Ma, Yao Liu, Jiabei Wang, Lianxin Liu

Schizochytrium sp. Extracted Lipids Prevent Alopecia by Enhancing Antioxidation and Inhibiting Ferroptosis of Dermal Papilla Cells

Zuye Zeng, Boyu Wang, Muhammad Ibrar, Ming Ying, Shuangfei Li, Xuewei Yang

Interaction mechanisms between autophagy and ferroptosis: Potential role in colorectal cancer

Xin-Ya Zeng, Xin-Ze Qiu, Jiang-Ni Wu, Sheng-Mei Liang, Jie-An Huang, Shi-Quan Liu

World Journal of Gastrointestinal Oncology.2023; 15(7): 1135. CrossRef

A Novel Bromophenol Compound from Leathesia nana Inhibits Breast Cancer in a Direct Tumor Killing and Immunotherapy Manner

Ruochen Sun, Mi Zhang, Bufan Li, Shan Jiang, Wanpeng Yu, Lina Yang, Yantao Han, Zhangfeng Zhong, Wenwen Zhao

“Double-Edged Sword” Effect of Reactive Oxygen Species (ROS) in Tumor Development and Carcinogenesis

Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy

Xiaogang Zheng, Xiaodong Jin, Fei Ye, Xiongxiong Liu, Boyi Yu, Zheng Li, Ting Zhao, Weiqiang Chen, Xinguo Liu, Cuixia Di, Qiang Li

Experimental Hematology & Oncology.2023;[Epub] CrossRef

Integrated single-cell and bulk RNA sequencing analysis identifies a prognostic signature related to ferroptosis dependence in colorectal cancer

Xiaochen Xu, Xinwen Zhang, Qiumei Lin, Yuling Qin, Yihao Liu, Weizhong Tang

Targeting Heat Shock Protein 27 and Fatty Acid Oxidation Augments Cisplatin Treatment in Cisplatin-Resistant Ovarian Cancer Cell Lines

James Patrick Heiserman, Zenab Minhas, Elahe Nikpayam, Dong-Joo Cheon

International Journal of Molecular Sciences.2023; 24(16): 12638. CrossRef

A planning strategy may reduce the risk of heart diseases and radiation pneumonia: Avoiding the specific heart substructures

AiHui Feng, YanHua Duan, ZhangRu Yang, Yan Shao, Hao Wang, Hua Chen, HengLe Gu, Ying Huang, ZhenJiong Shen, Xufei Wang, ZhiYong Xu

Journal of Applied Clinical Medical Physics.2023;[Epub] CrossRef

Ferroptosis and EMT: key targets for combating cancer progression and therapy resistance

Yuqing Ren, Xiangrong Mao, Hui Xu, Qin Dang, Siyuan Weng, Yuyuan Zhang, Shuang Chen, Shutong Liu, Yuhao Ba, Zhaokai Zhou, Xinwei Han, Zaoqu Liu, Guojun Zhang

Cellular and Molecular Life Sciences.2023;[Epub] CrossRef

Sinularin Exerts Anti-cancer Effects by Inducing Oxidative Stress-mediated Ferroptosis, Apoptosis, and Autophagy in Prostate Cancer Cells

ZhengPing Wu, MengQiao Su, HanWu Chen, XuZhou Chen, Chung-Yi Chen, LiJie An, ZiChen Shao, XiaoYu Liu, Yi Lin, Ai-Jun OuYang, Chi-Ming Liu

Anti-Cancer Agents in Medicinal Chemistry.2023; 23(12): 1457. CrossRef

Ruihan Yan, Bingyi Lin, Wenwei Jin, Ling Tang, Shuming Hu, Rong Cai

SOCS1 acts as a ferroptosis driver to inhibit the progression and chemotherapy resistance of triple-negative breast cancer

Yiding Wang, Xiaoling Pang, Yuexin Liu, Guiling Mu, Qian Wang

Verteporfin Exerts Anticancer Effects and Reverses Resistance to Paclitaxel via Inducing Ferroptosis in Esophageal Squamous Cell Cancer Cells

Xue-Wei Wang, Zi-Yi Yang, Ting Li, Xin-Ran Zhao, Xiao-Zhong Li, Xiao-Xia Wang

Yuyan Xie, Yang Zhou, Jiale Wang, Lijuan Du, Yuanyuan Ren, Fang Liu

Ferroptosis regulation by methylation in cancer

Mengqiu Hao, Yixin Jiang, Yang Zhang, Xuyang Yang, Junhong Han

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.2023; 1878(6): 188972. CrossRef

FOXA2 Suppression by TRIM36 Exerts Anti‐Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4‐Regulated Ferroptosis

Xin Liu, Chunli Yan, Chunxiao Chang, Fansong Meng, Wenjie Shen, Song Wang, Yi Zhang

Creation of a Rat Takotsubo Syndrome Model and Utilization of Machine Learning Algorithms for Screening Diagnostic Biomarkers

Hongyu Huai, Junliang Li, Xiangjie Zhang, Qiang Xu, Huan Lan

Journal of Inflammation Research.2023; Volume 16: 4833. CrossRef

Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes

Qi Li, Hengchen Liu, Yun Jin, Yuanquan Yu, Yihang Wang, Di Wu, Yinghao Guo, Longfu Xi, Dan Ye, Yanzhi Pan, Xiaoxiao Zhang, Jiangtao Li

Computers in Biology and Medicine.2023; 165: 107370. CrossRef

Ferroptosis as a promising therapeutic strategy for melanoma

Na Ta, Xiaodong Jiang, Yongchun Zhang, Hongquan Wang

The crosstalk between ferroptosis and anti‐tumor immunity in the tumor microenvironment: molecular mechanisms and therapeutic controversy

Cancer Communications.2023; 43(10): 1071. CrossRef

Impact of ferroptosis on preeclampsia: A review

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Biomedicine & Pharmacotherapy.2023; 167: 115466. CrossRef

Endogenous molecule-targeted fluorescent probes for ferroptosis visualization: Current progress and future prospects

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Coordination Chemistry Reviews.2023; 496: 215432. CrossRef

Selenium intake and multiple health-related outcomes: an umbrella review of meta-analyses

Puze Wang, Bo Chen, Yin Huang, Jin Li, Dehong Cao, Zeyu Chen, Jinze Li, Biao Ran, Jiahao Yang, Ruyi Wang, Qiang Wei, Qiang Dong, Liangren Liu

Recent advances of ferroptosis in tumor: From biological function to clinical application

Biomedicine & Pharmacotherapy.2023; 166: 115419. CrossRef

Regulation of m6A modification on ferroptosis and its potential significance in radiosensitization

Xun Chen, Lejia Zhang, Yi He, Siyuan Huang, Shangwu Chen, Wei Zhao, Dongsheng Yu

Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance

Simona D’Aprile, Simona Denaro, Anna Maria Pavone, Sebastiano Giallongo, Cesarina Giallongo, Alfio Distefano, Lucia Salvatorelli, Filippo Torrisi, Raffaella Giuffrida, Stefano Forte, Daniele Tibullo, Giovanni Li Volti, Gaetano Magro, Nunzio Vicario, Rosal

Journal of Translational Medicine.2023;[Epub] CrossRef

The recent advancements of ferroptosis in the diagnosis, treatment and prognosis of ovarian cancer

Implanted, Wireless, Self‐Powered Photodynamic Therapeutic Tablet Synergizes with Ferroptosis Inducer for Effective Cancer Treatment

Pingjin Zou, Rui Lin, Zengyi Fang, Junyang Chen, Hongye Guan, Jie Yin, Zhiheng Chang, Lili Xing, Jinyi Lang, Xinyu Xue, Meihua Chen

Variation of Plasma Damage-Associated Molecular Patterns in Patients with Advanced Solid Tumors after Standard of Care Systemic Treatment

Vicente Valentí, Laia Capdevila, Isabel Ruiz, Javier Ramos, Joan Badía, Susana Blázquez, Óscar Villuendas, Cristina Pérez, Laura Fernández-Sender, Mónica Córdoba, Carlos Alonso-Villaverde

Engineered exosomes-based theranostic strategy for tumor metastasis and recurrence

Min Deng, Shuang Wu, Peizheng Huang, Yun Liu, Chong Li, Ji Zheng

Asian Journal of Pharmaceutical Sciences.2023; 18(6): 100870. CrossRef

Molecular Mechanisms of Ferroptosis and Its Role in Viral Pathogenesis

Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

Abdullah A. Osman, Emre Arslan, Mason Bartels, Chieko Michikawa, Antje Lindemann, Katarzyna Tomczak, Wangjie Yu, Vlad Sandulache, Wencai Ma, Li Shen, Jing Wang, Anand K. Singh, Mitchell J. Frederick, Nakia D. Spencer, Jeffery Kovacs, Timothy Heffernan, Wi

Clinical Cancer Research.2023; 29(7): 1344. CrossRef

Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases

Yumin Wang, Jing Hu, Shuang Wu, Joshua S. Fleishman, Yulin Li, Yinshi Xu, Wailong Zou, Jinhua Wang, Yukuan Feng, Jichao Chen, Hongquan Wang

Signal Transduction and Targeted Therapy.2023;[Epub] CrossRef

Moving beyond cisplatin resistance: mechanisms, challenges, and prospects for overcoming recurrence in clinical cancer therapy

Rui Fu, Borui Zhao, Min Chen, Xiaolong Fu, Qian Zhang, Yange Cui, Xin Hu, Wei Zhou

ALOX5 deficiency contributes to bladder cancer progression by mediating ferroptosis escape

Tianyao Liu, Xinyan Xu, Jiazheng Li, Ming Bai, Wenjie Zhu, Yanqing Liu, Siyang Liu, Zihan Zhao, Tianhang Li, Ning Jiang, Yuhao Bai, Qingyang Jin, Yulin Zhang, Yufeng Zheng, Shengkai Zhou, Shoubin Zhan, Ying Sun, Gaoli Liang, Yang Luo, Xi Chen, Hongqian Gu

NeuroD1-GPX4 signaling leads to ferroptosis resistance in hepatocellular carcinoma

Ping Huang, Wei Duan, Cao Ruan, Lingxian Wang, Rendy Hosea, Zheng Wu, Jianting Zeng, Shourong Wu, Vivi Kasim, Carmen Priolo

Ferroptosis: An emerging therapeutic opportunity for cancer

Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy

Nasim Ebrahimi, Samaneh Adelian, Siavash Shakerian, Maral Afshinpour, Siavash Rahimian Chaleshtori, Nadi Rostami, Fatemeh Rezaei-Tazangi, Sheida Beiranvand, Michael R. Hamblin, Amir Reza Aref

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Programmed cell death in aortic aneurysm and dissection: A potential therapeutic target

Abhijit Chakraborty, Yang Li, Chen Zhang, Yanming Li, Scott A. LeMaire, Ying H. Shen

Journal of Molecular and Cellular Cardiology.2022; 163: 67. CrossRef

Emerging role of ferroptosis in breast cancer: New dawn for overcoming tumor progression

Pharmacology & Therapeutics.2022; 232: 107992. CrossRef

GALNT14 regulates ferroptosis and apoptosis of ovarian cancer through the EGFR/mTOR pathway

Hua-wen Li, Mu-biao Liu, Xue Jiang, Ting Song, Shu-xian Feng, Jing-ya Wu, Peng-fei Deng, Xiao-yu Wang

Research progress on the occurrence and therapeutic mechanism of ferroptosis in NSCLC

Naunyn-Schmiedeberg's Archives of Pharmacology.2022; 395(1): 1. CrossRef

A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury

Chenrui Wu, Mengran Du, Renqiang Yu, Yuqi Cheng, Biying Wu, Jiayuanyuan Fu, Weilin Tan, Qiang Zhou, Ehab Balawi, Z.B. Liao

Free Radical Biology and Medicine.2022; 178: 271. CrossRef

The Role of Ferroptosis Signature in Overall Survival and Chemotherapy of Pancreatic Adenocarcinoma

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The Potential Mechanisms by which Artemisinin and Its Derivatives Induce Ferroptosis in the Treatment of Cancer

Yingying Hu, Nan Guo, Ting Yang, Jianghong Yan, Wenjun Wang, Xiang Li, Julio J. Ochoa

Oxidative Medicine and Cellular Longevity.2022; 2022: 1. CrossRef

Induction and application of ferroptosis in cancer therapy

Molecular regulatory mechanism of ferroptosis and its role in gastrointestinal oncology: Progress and updates

Fan Yang, Si-Yu Sun, Sheng Wang, Jin-Tao Guo, Xiang Liu, Nan Ge, Guo-Xin Wang

World Journal of Gastrointestinal Oncology.2022; 14(1): 1. CrossRef

Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3

Fengfan Liu, Xiang Cheng, Shuang Wu, Bei Hu, Chen Yang, Shufen Deng, Qiwen Shi

Environmental Toxicology.2022; 37(5): 1093. CrossRef

Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products

Chun Ge, Sujie Zhang, Huiwen Mu, Shaojun Zheng, Zhaoyi Tan, Xintong Huang, Chen Xu, Jianjun Zou, Yubing Zhu, Dong Feng, Jiye Aa

Frontiers in Cell and Developmental Biology.2022;[Epub] CrossRef

Identification of Five Ferroptosis-Related LncRNAs as Novel Prognosis and Diagnosis Signatures for Renal Cancer

Xiangjun Shu, Zaiqi Zhang, Zhi-Yong Yao, Xiao-Liang Xing

Frontiers in Molecular Biosciences.2022;[Epub] CrossRef

Modulations of ferroptosis in lung cancer therapy

Expert Opinion on Therapeutic Targets.2022; 26(2): 133. CrossRef

Epigenetic landscape of drug responses revealed through large-scale ChIP-seq data analyses

Zhaonan Zou, Michio Iwata, Yoshihiro Yamanishi, Shinya Oki

Ferroptosis Mediation Patterns Reveal Novel Tool to Implicate Immunotherapy and Multi-Omics Characteristics in Bladder Cancer

Jingchao Liu, Zhipeng Zhang, Wei Zhang, Lingfeng Meng, Jiawen Wang, Zhengtong Lv, Haoran Xia, Meng Wu, Yaoguang Zhang, Jianye Wang

Frontiers in Cell and Developmental Biology.2022;[Epub] CrossRef

Ferroptosis and metabolic dysfunction‐associated fatty liver disease: Is there a link?

Gong Feng, Christopher D. Byrne, Giovanni Targher, Fudi Wang, Ming‐Hua Zheng

Ferroptosis: A Trusted Ally in Combating Drug Resistance in Cancer

Current Medicinal Chemistry.2022; 29(1): 41. CrossRef

Targeting Regulated Cell Death with Pharmacological Small Molecules: An Update on Autophagy-Dependent Cell Death, Ferroptosis, and Necroptosis in Cancer

Journal of Medicinal Chemistry.2022; 65(4): 2989. CrossRef

Albumin-Based Therapeutics Capable of Glutathione Consumption and Hydrogen Peroxide Generation for Synergetic Chemodynamic and Chemotherapy of Cancer

Guangbao Yang, Dongdong Wang, Soo Zeng Fiona Phua, Anivind Kaur Bindra, Cheng Qian, Rui Zhang, Liang Cheng, Guofeng Liu, Hongwei Wu, Zhuang Liu, Yanli Zhao

A Ferroptosis-Related lncRNA Model to Enhance the Predicted Value of Cervical Cancer

Zhaojing Jiang, Jingyu Li, Wenqing Feng, Yujie Sun, Junguo Bu, Fu Wang

Lei Zhao, Xiaoxue Zhou, Feng Xie, Lei Zhang, Haiyan Yan, Jun Huang, Chong Zhang, Fangfang Zhou, Jun Chen, Long Zhang

Schisandrin B suppresses gastric cancer cell growth and enhances the efficacy of chemotherapy drug 5-FU in vitro and in vivo

Leye He, Hao Chen, Qinqin Qi, Nan Wu, Ying Wang, Mengxia Chen, Qian Feng, Buyuan Dong, Rong Jin, Lei Jiang

European Journal of Pharmacology.2022; 920: 174823. CrossRef

Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis

Hsin-Chih Chen, Han-Hsuan Tang, Wei-Hsiang Hsu, Shan-Ying Wu, Wen-Hsing Cheng, Bao-Yuan Wang, Chun-Li Su

Ferroptosis in Cancer Immunotherapy—Implications for Hepatocellular Carcinoma

Johanna Kusnick, Alix Bruneau, Frank Tacke, Linda Hammerich

Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1

Insights Into Ferroptosis, a Novel Target for the Therapy of Cancer

Hong-Tao Wang, Jie Ju, Shao-Cong Wang, Yu-Hui Zhang, Cui-Yun Liu, Tao Wang, Xue Yu, Fei Wang, Xue-Ru Cheng, Kun Wang, Zhao-Yang Chen

The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis

Biochemical and Biophysical Research Communications.2022; 603: 153. CrossRef

Ferroptosis in hematological malignancies and its potential network with abnormal tumor metabolism

Jiasi Zhang, Yuxi Liu, Qun Li, Aoshuang Xu, Yu Hu, Chunyan Sun

Biomedicine & Pharmacotherapy.2022; 148: 112747. CrossRef

Metabolic regulation of ferroptosis in the tumor microenvironment

Journal of Biological Chemistry.2022; 298(3): 101617. CrossRef

The Role of Ferroptosis in the Treatment and Drug Resistance of Hepatocellular Carcinoma

Siqi Zhao, Wubin Zheng, Chao Yu, Gaoxin Xu, Xinyi Zhang, Chao Pan, Yongheng Feng, Kunxing Yang, Jin Zhou, Yong Ma

Frontiers in Cell and Developmental Biology.2022;[Epub] CrossRef

Nan Guo, Yan Chen, Yuhong Zhang, Yonghao Deng, Fancai Zeng, Xiang Li

Scutellaria barbata Inhibits Hepatocellular Carcinoma Tumorigenicity by Inducing Ferroptosis of Hepatocellular Carcinoma Cells

Yue Li, Jiongshan Zhang, Kun Zhang, Yan Chen, Wei Wang, Hongjie Chen, Zengcheng Zou, Yongwei Li, Min Dai

One Ferroptosis-Related Gene-Pair Signature Serves as an Original Prognostic Biomarker in Lung Adenocarcinoma

Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model

Jingyu Wang, Yaqing Wang, Yi Liu, Xintian Cai, Xin Huang, Wenjing Fu, Lei Wang, Lihua Qiu, Junying Li, Li Sun

Targeting ferroptosis as a vulnerability in cancer

AXL inhibition improves BRAF-targeted treatment in melanoma

Marta Nyakas, Karianne Giller Fleten, Mads Haugland Haugen, Nikolai Engedal, Christina Sveen, Inger Nina Farstad, Vivi Ann Flørenes, Lina Prasmickaite, Gunhild Mari Mælandsmo, Kotryna Seip

Role of Induced Programmed Cell Death in the Chemopreventive Potential of Apigenin

International Journal of Molecular Sciences.2022; 23(7): 3757. CrossRef

Boosting ferroptosis via abplatin(iv) for treatment of platinum-resistant recurrent ovarian cancer

Wenwen Wang, Jing Cai, Jiayi Wen, Xinyi Li, Yingjie Yu, Lingpu Zhang, Qing Han, Zheng Wei, Yujia Ma, Feiquan Ying, Xiaohan Xu, Wenhan Li, Qiang Yang, Si Sun, Xiaoqi He, Liqiong Cai, Haihua Xiao, Zehua Wang

A GSH-depleted platinum(IV) prodrug triggers ferroptotic cell death in breast cancer

Dachuan Qi, Lei Xing, Lijun Shen, Wenshuang Sun, Cheng Cai, Chunhua Xue, Xuwei Song, Hua Yu, Hulin Jiang, Chengjun Li, Qingri Jin, Zhiqi Zhang

Chinese Chemical Letters.2022; 33(10): 4595. CrossRef

miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways

Guoshu Bi, Jiaqi Liang, Mengnan Zhao, Huan Zhang, Xing Jin, Tao Lu, Yuansheng Zheng, Yunyi Bian, Zhencong Chen, Yiwei Huang, Valeria Besskaya, Cheng Zhan, Qun Wang, Lijie Tan

Molecular Therapy - Nucleic Acids.2022; 28: 366. CrossRef

Non-coding RNAs and ferroptosis: potential implications for cancer therapy

Amar Balihodzic, Felix Prinz, Michael A. Dengler, George A. Calin, Philipp J. Jost, Martin Pichler

Cell Death & Differentiation.2022; 29(6): 1094. CrossRef

SLC7A11, a Potential Therapeutic Target Through Induced Ferroptosis in Colon Adenocarcinoma

Xin Cheng, Yadong Wang, Liangchao Liu, Chenggang Lv, Can Liu, Jingyun Xu

Frontiers in Molecular Biosciences.2022;[Epub] CrossRef

Molecular mechanisms of reactive oxygen species in regulated cell deaths: Impact of ferroptosis in cancer therapy

Morteza Golbashirzadeh, Hamid Reza Heidari, Ahmad Yari Khosroushahi

Exosomes and ferroptosis: roles in tumour regulation and new cancer therapies

Yixin Shi, Bingrun Qiu, Linyang Huang, Jie Lin, Yiling Li, Yiting Ze, Chenglong Huang, Yang Yao

Induction of ferroptosis by carnosic acid-mediated inactivation of Nrf2/HO-1 potentiates cisplatin responsiveness in OSCC cells

Molecular and Cellular Probes.2022; 64: 101821. CrossRef

Cullin-9/p53 mediates HNRNPC degradation to inhibit erastin-induced ferroptosis and is blocked by MDM2 inhibition in colorectal cancer

Lv Yang, Tang WenTao, Zhang ZhiYuan, Lin Qi, Luo YuXiang, Zheng Peng, Li Ke, Jia XiaoNa, Pang YuZhi, Ji MeiLing, Feng QingYang, He GuoDong, Wang YueXiang, Xu JianMin

Excessive selenium affects neural development and locomotor behavior of zebrafish embryos

Guang Zhao, Jun Hu, Meng Gao, Yuejie Zhu, Yijiang Hong

Ecotoxicology and Environmental Safety.2022; 238: 113611. CrossRef

Hitting Multiple Cellular Targets in Triple-Negative Breast Cancer Using Dual-Action Cisplatin(IV) Prodrugs for Safer Synergistic Chemotherapy

Tushar Date, Kaushik Kuche, Dasharath Chaudhari, Rohan Ghadi, Deepak Kumar Sahel, Deepak Chitkara, Sanyog Jain

ACS Biomaterials Science & Engineering.2022; 8(6): 2349. CrossRef

Prospective Application of Ferroptosis in Hypoxic Cells for Tumor Radiotherapy

Jing Su, Qin Zhao, Zhuangzhuang Zheng, Huanhuan Wang, Chenbin Bian, Lingbin Meng, Ying Xin, Xin Jiang

Solasonine Causes Redox Imbalance and Mitochondrial Oxidative Stress of Ferroptosis in Lung Adenocarcinoma

Yao-Ying Zeng, Ying-Bin Luo, Xu-Dong Ju, Bo Zhang, Ya-Jing Cui, Yan-Bin Pan, Jian-Hui Tian, Wen-Jing Teng, Jianchun Wu, Yan Li

Ferroptosis and Tumor Drug Resistance: Current Status and Major Challenges

Zhenyu Nie, Mei Chen, Yuanhui Gao, Denggao Huang, Hui Cao, Yanling Peng, Na Guo, Fei Wang, Shufang Zhang

Post-Translational Modifications of p53 in Ferroptosis: Novel Pharmacological Targets for Cancer Therapy

Le Zhang, Ningning Hou, Bing Chen, Chengxia Kan, Fang Han, Jingwen Zhang, Xiaodong Sun

Pharmacological Targeting of Ferroptosis in Cancer Treatment

Mehdi Rabiee Valashedi, Amirsadegh Nikoo, Nima Najafi-Ghalehlou, Kazuo Tomita, Yoshikazu Kuwahara, Tomoaki Sato, Amaneh Mohammadi Roushandeh, Mehryar Habibi Roudkenar

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Flavonoid 4,4′-dimethoxychalcone induced ferroptosis in cancer cells by synergistically activating Keap1/Nrf2/HMOX1 pathway and inhibiting FECH

Changmei Yang, Tianxiang Wang, Yujiao Zhao, Xianbin Meng, Wenxi Ding, Qingtao Wang, Chongdong Liu, Haiteng Deng

Free Radical Biology and Medicine.2022; 188: 14. CrossRef

Crosstalk between ferroptosis and stress—Implications in cancer therapeutic responses

Cheng Zhang, Jiao‐jiao Yu, Chen Yang, Shuang Shang, Xiao‐xi Lv, Bing Cui, Fang Hua

Molecular mechanisms of ferroptosis and its role in prostate cancer therapy

Shaokun Wang, Wei Wei, Ning Ma, Yongliang Qu, Qiuju Liu

Critical Reviews in Oncology/Hematology.2022; 176: 103732. CrossRef

Kuan Wang, Yi-Fong Chen, Yu-Chen S. H. Yang, Haw-Ming Huang, Sheng-Yang Lee, Ya-Jung Shih, Zi-Lin Li, Jacqueline Whang-Peng, Hung-Yun Lin, Paul J. Davis

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CRISPR/Cas9-mediated knockout of Lcn2 in human breast cancer cell line MDA-MB-231 ameliorates erastin-mediated ferroptosis and increases cisplatin vulnerability

Mehdi Rabiee Valashedi, Amaneh Mohammadi Roushandeh, Kazuo Tomita, Yoshikazu Kuwahara, Zahra Pourmohammadi-Bejarpasi, Pouya Safarzadeh Kozani, Tomoaki Sato, Mehryar Habibi Roudkenar

Turkish Veterinary Journal.2022; 4(1): 24. CrossRef

Microwave assisted extraction, characterization of a polysaccharide from Salvia miltiorrhiza Bunge and its antioxidant effects via ferroptosis-mediated activation of the Nrf2/HO-1 pathway

Huanhuan Meng, Jianjun Wu, Li Shen, Guangwei Chen, Liang Jin, Mengxia Yan, Haitong Wan, Yu He

International Journal of Biological Macromolecules.2022; 215: 398. CrossRef

Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy

Weitong Gao, Xueying Wang, Yang Zhou, Xueqian Wang, Yan Yu

Signal Transduction and Targeted Therapy.2022;[Epub] CrossRef

Predicting prognosis and clinical features of the tumor microenvironment based on ferroptosis score in patients with breast cancer

Multifaceted Roles of Ferroptosis in Lung Diseases

Frontiers in Molecular Biosciences.2022;[Epub] CrossRef

Comprehensive Analysis of a Ferroptosis-Related lncRNA Signature for Predicting Prognosis and Immune Landscape in Osteosarcoma

Yiming Zhang, Rong He, Xuan Lei, Lianghao Mao, Zhengyu Yin, Xinyu Zhong, Wenbing Cao, Qiping Zheng, Dapeng Li

Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

Bartosz Wiernicki, Sophia Maschalidi, Jonathan Pinney, Sandy Adjemian, Tom Vanden Berghe, Kodi S. Ravichandran, Peter Vandenabeele

Induction of Ferroptosis by Ophiopogonin-B Through Regulating the Gene Signature AURKA in NSCLC

Liqiu Li, Qian Gao, Jin Wang, Ling Gu, Zhihui Li, Shiping Zhang, Cheng Hu, Menglin He, Yulin Wang, Zixuan Wang, Yongxiang Yi, Jin Fu, Xiongfei Zhang, Fei Ge, Meijuan Chen, Xu Zhang

Combination regimen of granulocyte colony-stimulating factor and recombinant human thrombopoietin improves the curative effect on elderly patients with leukemia through inducing pyroptosis and ferroptosis of leukemia cells

Role of Heme Oxygenase in Gastrointestinal Epithelial Cells

Capsaicin induces ferroptosis of NSCLC by regulating SLC7A11/GPX4 signaling in vitro

Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy

Devangkumar Maru, Akhil Hothi, Chintan Bagariya, Anmol Kumar

Current Cancer Drug Targets.2022; 22(3): 234. CrossRef

Amorphous ferric oxide-coating selenium core–shell nanoparticles: a self-preservation Pt(iv) platform for multi-modal cancer therapies through hydrogen peroxide depletion-mediated anti-angiogenesis, apoptosis and ferroptosis

Zhaowei Xu, Qingdong Li, Caiyun Zhang, Peng Wang, Xiaotong Xu, Lang Ran, Li Zhang, Geng Tian, Guilong Zhang

ARPC1A is regulated by STAT3 to inhibit ferroptosis and promote prostate cancer progression

Junpeng Ji, Huibing Li, Wenjun Wang, Bo Yuan, Tianyu Shen

Shinya Toyokuni, Yingyi Kong, Hao Zheng, Yuki Maeda, Yashiro Motooka, Shinya Akatsuka

Journal of Clinical Biochemistry and Nutrition.2022; 71(2): 78. CrossRef

Multi-platform-based characterization of ferroptosis in human colorectal cancer

Yafang Zhong, Wei Zhang, Haiyan Yu, Liewen Lin, Xucan Gao, Jingquan He, Dandan Li, Yumei Chen, Zhipeng Zeng, Yong Xu, Donge Tang, Yong Dai

Knockdown of RRM1 in tumor cells promotes radio-/chemotherapy induced ferroptosis by regulating p53 ubiquitination and p21-GPX4 signaling axis

Yang Gao, Bin Chen, Ruru Wang, An Xu, Lijun Wu, Huayi Lu, Guoping Zhao

Revisiting “BAP1ness” in Malignant Pleural Mesothelioma

Journal of Thoracic Oncology.2022; 17(8): e67. CrossRef

Focus on ferroptosis regulation: Exploring novel mechanisms and applications of ferroptosis regulator

Tian-Liang Ma, Jing-Xian Chen, Peng Zhu, Chao-Bin Zhang, Yong Zhou, Jia-Xi Duan

The crosstalk effect between ferrous and other ions metabolism in ferroptosis for therapy of cancer

Kun Ke, Li Li, Chao Lu, Qicong Zhu, Yuanyu Wang, Yiping Mou, Huiju Wang, Weiwei Jin

Regulated cell death (RCD) in cancer: key pathways and targeted therapies

Fu Peng, Minru Liao, Rui Qin, Shiou Zhu, Cheng Peng, Leilei Fu, Yi Chen, Bo Han

Signal Transduction and Targeted Therapy.2022;[Epub] CrossRef

Frontiers of ferroptosis research: An analysis from the top 100 most influential articles in the field

Kunming Cheng, Qiang Guo, Zefeng Shen, Weiguang Yang, Yan Zhou, Zaijie Sun, Xiuhua Yao, Haiyang Wu

Ferroptosis and Its Multifaceted Role in Cancer: Mechanisms and Therapeutic Approach

Heshu Chen, Chenyu Wang, Zemin Liu, Xinmiao He, Wenjie Tang, Liuqin He, Yanzhong Feng, Di Liu, Yulong Yin, Tiejun Li

Inhibition of the PIN1-NRF2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells

Zheng Zhang, Qiangsheng Hu, Shuang Ye, Libing Xiang

Acta Biochimica et Biophysica Sinica.2022;[Epub] CrossRef

Adipocyte‐Derived Exosomal MTTP Suppresses Ferroptosis and Promotes Chemoresistance in Colorectal Cancer

Qiumo Zhang, Ting Deng, Hongdian Zhang, Duo Zuo, Qihang Zhu, Ming Bai, Rui Liu, Tao Ning, Le Zhang, Zhentao Yu, Haiyang Zhang, Yi Ba

Ferroptosis-Related Long Noncoding RNAs Have Excellent Predictive Ability for Multiomic Characteristics of Bladder Cancer

Jingchao Liu, Jingyi Cui, Shuangyi Zhao, Meng Wu, Jiawen Wang, Yaoguang Zhang, Bin Jin, Jianye Wang, Lianxiang Luo

Oxidative Medicine and Cellular Longevity.2022; 2022: 1. CrossRef

Neratinib inhibits proliferation and promotes apoptosis of acute myeloid leukemia cells by activating autophagy‐dependent ferroptosis

Hongxia Ma, Yang Liu, Zhen Miao, Shijia Cheng, Yunan Zhu, Yifan Wu, Xinxin Fan, Jing Yang, Xingang Li, Liyin Guo

Drug Development Research.2022; 83(7): 1641. CrossRef

System Xc−/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

Feng-Jiao Li, Hui-Zhi Long, Zi-Wei Zhou, Hong-Yu Luo, Shuo-Guo Xu, Li-Chen Gao

The Ferroptosis Molecular Subtype Reveals Characteristics of the Tumor Microenvironment, Immunotherapeutic Response, and Prognosis in Gastric Cancer

Xiao Xu, Na Zhou, Hongwei Lan, Fangfang Yang, Bowen Dong, Xiaochun Zhang

International Journal of Molecular Sciences.2022; 23(17): 9767. CrossRef

The Role of Programmed Necrosis in Colorectal Cancer

Yu-Qiang Yu, Reyes Gamez-Belmonte, Jay V. Patankar, Eva Liebing, Christoph Becker

Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis

Huan Feng, Qi Liu, Zhiyao Deng, Hao Li, Huajie Zhang, Jingyu Song, Xiaming Liu, Jihong Liu, Bo Wen, Tao Wang

Stem Cell Research & Therapy.2022;[Epub] CrossRef

Long non-coding RNA OGFRP1 regulates cell proliferation and ferroptosis by miR-299-3p/SLC38A1 axis in lung cancer

Liang Liu, Shengtian Su, Dan Ye, Zhigao Yu, Wenjing Lu, Xiaoju Li

Ferroptosis: A mixed blessing for infectious diseases

Leyao Xiao, Huanshao Huang, Shuhao Fan, Biying Zheng, Jianguo Wu, Junai Zhang, Jiang Pi, Jun-Fa Xu

More than a duologue: In-depth insights into epitranscriptomics and ferroptosis

Justin Chak Ting Cheung, Guangzheng Deng, Nathalie Wong, Yujuan Dong, Simon Siu Man Ng

Frontiers in Cell and Developmental Biology.2022;[Epub] CrossRef

PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer

Dongya Shen, Jia Luo, Ling Chen, Wenjuan Ma, Xiaoyuan Mao, Yu Zhang, Juyan Zheng, Yang Wang, Jielin Wan, Shiyu Wang, Jing Ouyang, Hanying Yi, Dongbo Liu, Weihua Huang, Wei Zhang, Zhaoqian Liu, Howard L. McLeod, Yijing He

Mechanisms and inhibitors of ferroptosis in psoriasis

Qiao Zhou, Lijing Yang, Ting Li, Kaiwen Wang, Xiaobo Huang, Jingfen Shi, Yi Wang

Frontiers in Molecular Biosciences.2022;[Epub] CrossRef

The pyroptosis-related gene signature predicts prognosis and indicates the immune microenvironment status of chronic lymphocytic leukemia

Yeqin Sha, Rui Jiang, Yi Miao, Shuchao Qin, Wei Wu, Yi Xia, Li Wang, Lei Fan, Hui Jin, Wei Xu, Jianyong Li, Huayuan Zhu

C-phycocyanin alleviated cisplatin-induced oxidative stress and inflammation via gut microbiota—metabolites axis in mice

Yubing Zhang, Lili Li, Song Qin, Jingyi Yuan, Xiaonan Xie, Fan Wang, Shanliang Hu, Yuetao Yi, Min Chen

KIF20A is associated with clinical prognosis and synergistic effect of gemcitabine combined with ferroptosis inducer in lung adenocarcinoma

Hua He, Lu Liang, Jingjing Huang, Shiyao Jiang, Yueying Liu, Xiaoyan Sun, Yi Li, Li Cong, Yiqun Jiang

Ferroptosis-based nano delivery systems targeted therapy for colorectal cancer: Insights and future perspectives

Chu Qiao, Haiying Wang, Qiutong Guan, Minjie Wei, Zhenhua Li

Asian Journal of Pharmaceutical Sciences.2022; 17(5): 613. CrossRef

The Relationship Between Ferroptosis and Diseases

Jinchang Lv, Biao Hou, Jiangang Song, Yunhua Xu, Songlin Xie

Journal of Multidisciplinary Healthcare.2022; Volume 15: 2261. CrossRef

Diclofenac Sensitizes Signet Ring Cell Gastric Carcinoma Cells to Cisplatin by Activating Autophagy and Inhibition of Survival Signal Pathways

Nang Lae Lae Phoo, Amonnat Sukhamwang, Pornngarm Dejkriengkraikul, Supachai Yodkeeree

International Journal of Molecular Sciences.2022; 23(20): 12066. CrossRef

Aberrant expression of microRNA-4443 (miR-4443) in human diseases

Yunan Mao, Jinze Shen, Yuchen Wu, Ruan Wenjing, Feng Zhu, Shiwei Duan

The differential usage of molecular machinery in brain cancer patients with iron-enriched glioma environments

Lucke-Wold Brandon, Diaz Michael Joseph, Song Joanna, Batchu Sai, Root Kevin, Patel Karan, Taneja Kamil

Journal of Surgery and Surgical Research.2022; 8(3): 030. CrossRef

Ferroptosis-related small-molecule compounds in cancer therapy: Strategies and applications

Linzhou Yin, Pengyu Liu, Yue Jin, Zunxi Ning, Yiren Yang, Huiyuan Gao

European Journal of Medicinal Chemistry.2022; 244: 114861. CrossRef

Integrative analysis of enrichment and prognostic value of ferroptosis-related genes and pathways in multiple myeloma

Qi Su, Qi Li, Weimin Zhang, Bingzong Li, Wenzhuo Zhuang

Regulation mechanism of ferroptosis and its research progress in tumor immunotherapy

Jing Xu, Xiaolin Lin, Ting Han, Qingqing Zhou, Yang Su, Shuqing Jiang, Xiuying Xiao, Tengfei Liu

Frontiers in Molecular Biosciences.2022;[Epub] CrossRef

Chuandong Gong, Qiankun Ji, Miaojing Wu, Zewei Tu, Kunjian Lei, Min Luo, Junzhe Liu, Li Lin, Kuangxun Li, Jingying Li, Kai Huang, Xingen Zhu

Journal of Cellular and Molecular Medicine.2022; 26(22): 5565. CrossRef

Ethoxyquin is a Competent Radical-Trapping Antioxidant for Preventing Ferroptosis in Doxorubicin Cardiotoxicity

Tomonori Tadokoro, Masataka Ikeda, Ko Abe, Tomomi Ide, Hiroko Deguchi Miyamoto, Shun Furusawa, Kosei Ishimaru, Masatsugu Watanabe, Akihito Ishikita, Shouji Matsushima, Tomoko Koumura, Ken-ichi Yamada, Hirotaka Imai, Hiroyuki Tsutsui

Journal of Cardiovascular Pharmacology.2022; 80(5): 690. CrossRef

Inhibition of AEBP1 predisposes cisplatin-resistant oral cancer cells to ferroptosis

Qianwen Zhou, Xiaoqi Wang, Yingxue Zhang, Lie Wang, Zhijun Chen

Ferroptosis: A new insight for treatment of acute kidney injury

Shiyang Li, Rui Wang, Yixue Wang, Yong Liu, Yingjin Qiao, Peipei Li, Jingfang Chen, Shaokang Pan, Qi Feng, Zhangsuo Liu, Dongwei Liu

The Impacts of Iron Overload and Ferroptosis on Intestinal Mucosal Homeostasis and Inflammation

International Journal of Molecular Sciences.2022; 23(22): 14195. CrossRef

Erastin enhances metastatic potential of ferroptosis-resistant ovarian cancer cells by M2 polarization through STAT3/IL-8 axis

Wei Cang, Anyue Wu, Liying Gu, Wenjing Wang, Qi Tian, Zhong Zheng, Lihua Qiu

International Immunopharmacology.2022; 113: 109422. CrossRef

A novel ferroptosis‑related gene signature for overall survival prediction and immune infiltration in patients with breast cancer

Yan Zhang, Yiran Liang, Yajie Wang, Fangzhou Ye, Xiaoli Kong, Qifeng Yang

International Journal of Oncology.2022;[Epub] CrossRef

Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival

Jonathan W. Villanueva, Lawrence Kwong, Teng Han, Salvador Alonso Martinez, Michael T. Shanahan, Matt Kanke, Lukas E. Dow, Charles G. Danko, Praveen Sethupathy

Emerging Potential Mechanism and Therapeutic Target of Ferroptosis in PDAC: A Promising Future

International Journal of Molecular Sciences.2022; 23(23): 15031. CrossRef

Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research

Xuhui Tong, Rong Tang, Mingming Xiao, Jin Xu, Wei Wang, Bo Zhang, Jiang Liu, Xianjun Yu, Si Shi

Journal of Hematology & Oncology.2022;[Epub] CrossRef

Xingyu Liu, Halahati Tuerxun, Yawen Li, Yaping Li, Yuanyuan He, Yuguang Zhao

Journal of Inflammation Research.2022; Volume 15: 6801. CrossRef

Low Sulfur Amino Acid, High Polyunsaturated Fatty Acid Diet Inhibits Breast Cancer Growth

Riccardo Turchi, Flavia Tortolici, Monica Benvenuto, Carolina Punziano, Anastasia De Luca, Stefano Rufini, Raffaella Faraonio, Roberto Bei, Daniele Lettieri-Barbato, Katia Aquilano

International Journal of Molecular Sciences.2022; 24(1): 249. CrossRef

Inhibition of SND1 overcomes chemoresistance in bladder cancer cells by promoting ferroptosis

Yu Zhao, Pengpeng Ren, Zhiqin Yang, Lei Wang, Changhua Hu

Comprehensive Analysis of the Expression and Clinical Significance of a Ferroptosis-Related Genome in Ovarian Serous Cystadenocarcinoma: A Study Based on TCGA Data

Cisplatin Promotes the Efficacy of ICI Therapy by Inducing Ferroptosis and Activating Neutrophils

Ziwei Zhou, Yiming Zhao, Si Chen, Guohui Cui, Wenkui Fu, Shouying Li, Xiaorong Lin, Hai Hu

Ferroptosis a Futuristic Roadmap for Cancer and Alzheimer's Disease

Gourav Singh, Prashant Kesharwani, Bhupendra Kumar, Indubhusan Mishra, Saroj Kumar, Gyan Modi

Regulation of ferroptosis in cancer cells by YAP/TAZ and Hippo pathways: The therapeutic implications

Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer

Jian-Shu Lou, Li-Ping Zhao, Zhi-Hui Huang, Xia-Yin Chen, Jing-Ting Xu, William Chi-Shing TAI, Karl W.K. Tsim, Yi-Tao Chen, Tian Xie

Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms

Lulu Sun, Hongliang Dong, Weiqun Zhang, Nan Wang, Na Ni, Xuelian Bai, Naiguo Liu

A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways

Wen-Tsan Chang, Yung-Ding Bow, Pei-Jung Fu, Chia-Yang Li, Chang-Yi Wu, Yi-Hua Chang, Yen-Ni Teng, Ruei-Nian Li, Mei-Chin Lu, Yi-Chang Liu, Chien-Chih Chiu, Cristina Angeloni

Oxidative Medicine and Cellular Longevity.2021; 2021: 1. CrossRef

Broadening horizons: the role of ferroptosis in cancer

Nature Reviews Clinical Oncology.2021; 18(5): 280. CrossRef

Elucidating the Roles of Fenton Reactants in Drug‐Treated Cells by Using a Selective Rhodamine‐Thiophenol Fluorogenic Sensor

Crosstalk between Macrophages, T Cells, and Iron Metabolism in Tumor Microenvironment

Lesang Shen, Yunxiang Zhou, Haifei He, Wuzhen Chen, Cameron Lenahan, Xiaoyi Li, Yongchuan Deng, Anwen Shao, Jian Huang, Ding Sheng Jiang

Oxidative Medicine and Cellular Longevity.2021; 2021: 1. CrossRef

Targeting the tumour microenvironment in platinum-resistant ovarian cancer

Cell death in head and neck cancer pathogenesis and treatment

Curcumin induces ferroptosis in non‐small‐cell lung cancer via activating autophagy

Xin Tang, Hui Ding, Maoli Liang, Xing Chen, Yuxia Yan, Nansheng Wan, Qianqian Chen, Jing Zhang, Jie Cao

Comprehensive Analysis Identifies Potential Ferroptosis-Associated mRNA Therapeutic Targets in Ovarian Cancer

Effect of Micelle-Incorporated Cisplatin With Sizes Ranging From 8 to 40 nm for the Therapy of Lewis Lung Carcinoma

Zhicheng Wang, Yumin Li, Tong Zhang, Hongxia Li, Zhao Yang, Cheng Wang

PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer

Ting Hong, Guang Lei, Xue Chen, He Li, Xiaoye Zhang, Nayiyuan Wu, Yu Zhao, Yilei Zhang, Jing Wang

Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer

Ali Ghoochani, En-Chi Hsu, Merve Aslan, Meghan A. Rice, Holly M. Nguyen, James D. Brooks, Eva Corey, Ramasamy Paulmurugan, Tanya Stoyanova

The emerging role of ferroptosis in intestinal disease

Shu Xu, Yao He, Lihui Lin, Peng Chen, Minhu Chen, Shenghong Zhang

Exosomal miR-4443 promotes cisplatin resistance in non-small cell lung carcinoma by regulating FSP1 m6A modification-mediated ferroptosis

The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis

Chunhua Rui, Shen-nan Shi, Wenqing Ren, Xia Qin, Chunlin Zhuang, Xiaofei Chen, Gang Chen, Jianqiang Yu, Hong-yang Wang, Zhenyu Cai

Biochemical Pharmacology.2021; 188: 114542. CrossRef

Emerging mechanisms and targeted therapy of ferroptosis in cancer

Haiyan Wang, Yan Cheng, Chao Mao, Shuang Liu, Desheng Xiao, Jun Huang, Yongguang Tao

Dihydroisotanshinone I induced ferroptosis and apoptosis of lung cancer cells

Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Geng-He Chang, Ming-Shao Tsai, Cheng-Ming Hsu, Reming-Albert Yeh, Li-Hsin Shu, Yu-Ching Cheng, Hung-Te Liu

Biomedicine & Pharmacotherapy.2021; 139: 111585. CrossRef

Erastin synergizes with cisplatin via ferroptosis to inhibit ovarian cancer growth in vitro and in vivo

Qi Cheng, Lingjie Bao, Mingqing Li, Kaikai Chang, Xiaofang Yi

Journal of Obstetrics and Gynaecology Research.2021; 47(7): 2481. CrossRef

Ferroptosis, radiotherapy, and combination therapeutic strategies

Guang Lei, Chao Mao, Yuelong Yan, Li Zhuang, Boyi Gan

Recent progress on targeting ferroptosis for cancer therapy

Guangxiang Xu, Han Wang, Xiaoling Li, Riming Huang, Lianxiang Luo

Biochemical Pharmacology.2021; 190: 114584. CrossRef

Deubiquitinase USP35 modulates ferroptosis in lung cancer via targeting ferroportin

Zheng Tang, Wanli Jiang, Ming Mao, Jinping Zhao, Jiakuan Chen, Nitao Cheng

Clinical and Translational Medicine.2021;[Epub] CrossRef

Nitroimidazoles Part 9. Synthesis, molecular docking, and anticancer evaluations of piperazine-tagged imidazole derivatives

Yaseen A. Al-Soud, Ala’a H. Al-Ahmad, Luay Abu-Qatouseh, Amneh Shtaiwi, Kafa’ A. S. Alhelal, Hossam H. Al-Suod, Sondos O. Alsawakhneh, Raed A. Al-Qawasmeh

Zeitschrift für Naturforschung B.2021; 76(5): 293. CrossRef

Defining a pharmacological inhibitor fingerprint for oxytosis/ferroptosis

David Soriano-Castell, Antonio Currais, Pamela Maher

Free Radical Biology and Medicine.2021; 171: 219. CrossRef

Construction and External Validation of a Ferroptosis-Related Gene Signature of Predictive Value for the Overall Survival in Bladder Cancer

Jingchao Liu, Hong Ma, Lingfeng Meng, Xiaodong Liu, Zhengtong Lv, Yaoguang Zhang, Jianye Wang

Frontiers in Molecular Biosciences.2021;[Epub] CrossRef

Tetrahedral DNA Nanostructures Inhibit Ferroptosis and Apoptosis in Cisplatin-induced Renal Injury

ACS Applied Bio Materials.2021; 4(6): 5026. CrossRef

Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice

Yasumasa Ikeda, Hirofumi Hamano, Yuya Horinouchi, Licht Miyamoto, Tasuku Hirayama, Hideko Nagasawa, Toshiaki Tamaki, Koichiro Tsuchiya

Journal of Trace Elements in Medicine and Biology.2021; 67: 126798. CrossRef

Expression and Prognostic Characteristics of Ferroptosis-Related Genes in Colon Cancer

International Journal of Molecular Sciences.2021; 22(11): 5652. CrossRef

Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling

Cellular & Molecular Biology Letters.2021;[Epub] CrossRef

A Promising Future of Ferroptosis in Tumor Therapy

Hui Wang, Danfeng Lin, Qianqian Yu, Zhouqi Li, Cameron Lenahan, Ying Dong, Qichun Wei, Anwen Shao

Frontiers in Cell and Developmental Biology.2021;[Epub] CrossRef

Role of Exosomal Non-coding RNAs in Gastric Cancer: Biological Functions and Potential Clinical Applications

Feng Hu, Jixuan Liu, Huibo Liu, Fan Li, Minjie Wan, Manli Zhang, Yanfang Jiang, Min Rao

Ferroptosis Holds Novel Promise in Treatment of Cancer Mediated by Non-coding RNAs

Yuan Zhi, Ling Gao, Baisheng Wang, Wenhao Ren, Kristina Xiao Liang, Keqian Zhi

Frontiers in Cell and Developmental Biology.2021;[Epub] CrossRef

Opportunities for Ferroptosis in Cancer Therapy

Kenji M. Fujihara, Bonnie Z. Zhang, Nicholas J. Clemons

Platinum drugs and taxanes: can we overcome resistance?

Elena V. Sazonova, Gelina S. Kopeina, Evgeny N. Imyanitov, Boris Zhivotovsky

Cisplatin synergizes with PRLX93936 to induce ferroptosis in non-small cell lung cancer cells

Zhigang Liang, Weijun Zhao, Xinjian Li, Longfei Wang, Lifei Meng, Rui Yu

Biochemical and Biophysical Research Communications.2021; 569: 79. CrossRef

Phosphorescent rhenium(I) complexes conjugated with artesunate: Mitochondrial targeting and apoptosis-ferroptosis dual induction

Rui-Rong Ye, Bi-Chun Chen, Jun-Jian Lu, Xiu-Rong Ma, Rong-Tao Li

Journal of Inorganic Biochemistry.2021; 223: 111537. CrossRef

CPEB1 enhances erastin‐induced ferroptosis in gastric cancer cells by suppressing twist1 expression

Jing Wang, Tao Wang, Yang Zhang, Jiaqi Liu, Jie Song, Yanlong Han, Lihong Wang, Shuang Yang, Lili Zhu, Rui Geng, Weimin Li, Xiaoguang Yu

DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism

Jing Du, Xu Wang, Yanchun Li, Xueying Ren, Yi Zhou, Wanye Hu, Chaoting Zhou, Qiangan Jing, Chen Yang, Luyang Wang, Huanjuan Li, Lijuan Fang, Yonglie Zhou, Xiangmin Tong, Ying Wang

Role of ferroptosis-related genes in prognostic prediction and tumor immune microenvironment in colorectal carcinoma

Chao Yang, Shuoyang Huang, Fengyu Cao, Yongbin Zheng

Ferroptosis in the tumor microenvironment: perspectives for immunotherapy

Huanji Xu, Di Ye, Meiling Ren, Hongying Zhang, Feng Bi

Trends in Molecular Medicine.2021; 27(9): 856. CrossRef

Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics

Khaled S Allemailem, Ahmad Almatroudi, Faris Alrumaihi, Saleh A Almatroodi, Mohammad O Alkurbi, Ghaiyda Talal Basfar, Arshad Husain Rahmani, Amjad Ali Khan

International Journal of Nanomedicine.2021; Volume 16: 5065. CrossRef

Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications

Xiao-Huan Tang, Ting Guo, Xiang-Yu Gao, Xiao-Long Wu, Xiao-Fang Xing, Jia-Fu Ji, Zi-Yu Li

Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology

Maria Scuto, Angela Trovato Salinaro, Isabella Caligiuri, Maria Laura Ontario, Valentina Greco, Nello Sciuto, Roberto Crea, Edward J. Calabrese, Flavio Rizzolio, Vincenzo Canzonieri, Vittorio Calabrese

Mechanisms of Ageing and Development.2021; 199: 111551. CrossRef

Establishment of a ferroptosis-related gene signature for prognosis in lung adenocarcinoma patients

Jingjing Cai, Chunyan Li, Hongsheng Li, Xiaoxiong Wang, Yongchun Zhou

A Novel Ferroptosis-Related Prognostic Signature Reveals Macrophage Infiltration and EMT Status in Bladder Cancer

Yilin Yan, Jinming Cai, Zhengnan Huang, Xiangqian Cao, Pengfei Tang, Zeyi Wang, Fang Zhang, Shujie Xia, Bing Shen

Frontiers in Cell and Developmental Biology.2021;[Epub] CrossRef

WITHDRAWN: Oroxylin A promotes therapeutic efficacy of cisplatin to suppress bladder cancer progression via inducing ferroptosis

Qiao Tang, Jiahui Jiang, Junyi Sun, Liang Tang, Xiangyang Zhang

Biochemical and Biophysical Research Communications.2021;[Epub] CrossRef

A novel survival model based on a Ferroptosis-related gene signature for predicting overall survival in bladder cancer

Yingchun Liang, Fangdie Ye, Chenyang Xu, Lujia Zou, Yun Hu, Jimeng Hu, Haowen Jiang

Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy

Rui Sha, Yaqian Xu, Chenwei Yuan, Xiaonan Sheng, Ziping Wu, Jing Peng, Yaohui Wang, Yanping Lin, Liheng Zhou, Shuguang Xu, Jie Zhang, Wenjin Yin, Jinsong Lu

Heat Shock Protein Beta 1 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Hepatocellular Carcinoma

Shengyi Long, Fang Peng, Baohui Song, Liang Wang, Jun Chen, Bingbing Shang

International Journal of General Medicine.2021; Volume 14: 5483. CrossRef

Current understanding of ferroptosis in the progression and treatment of pancreatic cancer

Shi Dong, Xin Li, Wenkai Jiang, Zhou Chen, Wence Zhou

Engineered exosome-like nanovesicles suppress tumor growth by reprogramming tumor microenvironment and promoting tumor ferroptosis

Shichuan Hu, Jinhu Ma, Chao Su, Yanwei Chen, Yongheng Shu, Zhongbing Qi, Bin Zhang, Gang Shi, Yan Zhang, Yuwei Zhang, Anliang Huang, Yueting Kuang, Ping Cheng

The Evolving Role of Ferroptosis in Breast Cancer: Translational Implications Present and Future

Hung-Yu Lin, Hui-Wen Ho, Yen-Hsiang Chang, Chun-Jui Wei, Pei-Yi Chu

Cashing in on ferroptosis against tumor cells: Usher in the next chapter

Mehdi Rabiee Valashedi, Nima Najafi-Ghalehlou, Amirsadegh Nikoo, Chia Bamshad, Kazuo Tomita, Yoshikazu Kuwahara, Tomoaki Sato, Amaneh Mohammadi Roushandeh, Mehryar Habibi Roudkenar

Ferroptosis: A New Promising Target for Lung Cancer Therapy

Rui Xiong, Ruyuan He, Bohao Liu, Wenyang Jiang, Bo Wang, Ning Li, Qing Geng, Manuela Curcio

Oxidative Medicine and Cellular Longevity.2021; 2021: 1. CrossRef

Glutathione peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis

Wenwen Liu, Yang Zhou, Wenzhe Duan, Jing Song, Song Wei, Shengkai Xia, Yingyan Wang, Xiaohui Du, Encheng Li, Caixia Ren, Wei Wang, Qimin Zhan, Qi Wang

Clinical and Translational Medicine.2021;[Epub] CrossRef

Targeting Ferroptosis for Lung Diseases: Exploring Novel Strategies in Ferroptosis-Associated Mechanisms

Tian-Liang Ma, Yong Zhou, Ci Wang, Lu Wang, Jing-Xian Chen, Hui-Hui Yang, Chen-Yu Zhang, Yong Zhou, Cha-Xiang Guan, Laura Bravo

Oxidative Medicine and Cellular Longevity.2021; 2021: 1. CrossRef

Ferroptosis is involved in the anti‑tumor effect of lycorine in renal cell carcinoma cells

Yang Du, Hong-Chao Zhao, Heng-Cheng Zhu, Yao Jin, Lei Wang

Identification of critical ferroptosis regulators in lung adenocarcinoma that RRM2 facilitates tumor immune infiltration by inhibiting ferroptotic death

Bufu Tang, Wangting Xu, Yajie Wang, Jinyu Zhu, Hailin Wang, Jianfei Tu, Qiaoyou Weng, Chunli Kong, Yang Yang, Rongfang Qiu, Zhongwei Zhao, Min Xu, Jiansong Ji

Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate

Longlong Li, Hao Li, Yongli Li, Jiankang Feng, Deng Guan, Yalei Zhang, Yun Fu, Shaoshan Li, Changzheng Li, Maria R. Ciriolo

Oxidative Medicine and Cellular Longevity.2021; 2021: 1. CrossRef

Construction and analysis of a novel ferroptosis‐related gene signature predicting prognosis in lung adenocarcinoma

A Ferroptosis-Related Gene Signature for Predicting the Prognosis and Drug Sensitivity of Head and Neck Squamous Cell Carcinoma

Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage

Bao Zheng, Xiwei Zhou, Lujun Pang, Yanjun Che, Xin Qi

Biological protein mediated ferroptotic tumor nanotherapeutics

Jiaoyang Tao, Chaoqun Li, Yongquan Zheng, Fengmei Wang, Meng Zhang, Xiaodong Wu, Yue Chen, Qingquan Zeng, Fengying Chen, Weidong Fei

Journal of Materials Chemistry B.2021; 9(45): 9262. CrossRef

Sikai Wu, Chengchu Zhu, Daolin Tang, Q. Ping Dou, Jianfei Shen, Xin Chen

Downregulation of Cx43 reduces cisplatin-induced acute renal injury by inhibiting ferroptosis

Meiling Yu, Zhuoheng Lin, Xiaoxue Tian, Shiyu Chen, Xinling Liang, Min Qin, Qian Zhu, Yuanyuan Wu, Shilong Zhong

Food and Chemical Toxicology.2021; 158: 112672. CrossRef

Prognostic significance of ferroptosis-related genes and their methylation in AML

Research progress on the mechanism of ferroptosis and its clinical application

Jiarui Xia, Huifang Si, Wu Yao, Chao Li, Guo Yang, Yangyang Tian, Changfu Hao

Experimental Cell Research.2021; 409(2): 112932. CrossRef

The mechanisms and therapeutic targets of ferroptosis in cancer

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The Regulatory Effects and the Signaling Pathways of Natural Bioactive Compounds on Ferroptosis

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Ferroptosis in Lung Cancer: From Molecular Mechanisms to Prognostic and Therapeutic Opportunities

Peyman Tabnak, Zanyar HajiEsmailPoor, Soroush Soraneh

Identification of the ferroptosis-related long non-coding RNAs signature to improve the prognosis prediction and immunotherapy response in patients with NSCLC

Meng Li, Yanpeng Zhang, Meng Fan, Hui Ren, Mingwei Chen, Puyu Shi

Ferroptosis in Non-Small Cell Lung Cancer: Progression and Therapeutic Potential on It

Jiayu Zou, Li Wang, Hailin Tang, Xiuxiu Liu, Fu Peng, Cheng Peng

International Journal of Molecular Sciences.2021; 22(24): 13335. CrossRef

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miR-6077 Promotes Cisplatin/Pemetrexed Resistance in Lung Adenocarcinoma by Targeting CDKN1A/Cell Cycle Arrest and KEAP1/Ferroptosis Pathways

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Drugs Repurposed as Antiferroptosis Agents Suppress Organ Damage, Including AKI, by Functioning as Lipid Peroxyl Radical Scavengers

Eikan Mishima, Emiko Sato, Junya Ito, Ken-ichi Yamada, Chitose Suzuki, Yoshitsugu Oikawa, Tetsuro Matsuhashi, Koichi Kikuchi, Takafumi Toyohara, Takehiro Suzuki, Sadayoshi Ito, Kiyotaka Nakagawa, Takaaki Abe

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CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer

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Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases

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Jie Li, Feng Cao, He-liang Yin, Zi-jian Huang, Zhi-tao Lin, Ning Mao, Bei Sun, Gang Wang

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Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs

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Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology

Rikki A. M. Brown, Kirsty L. Richardson, Tasnuva D. Kabir, Debbie Trinder, Ruth Ganss, Peter J. Leedman

Nonhomologous end-joining repair is likely involved in the repair of double-stranded DNA breaks induced by riluzole in melanoma cells

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The multifaceted role of reactive oxygen species in tumorigenesis

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The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy

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Molecular Mechanisms of Ferroptosis and Its Role in Pulmonary Disease

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Ferroptosis and Cancer: Mitochondria Meet the “Iron Maiden” Cell Death

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Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress

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Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression

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Systematic analysis of the ABC transporter family in hepatocellular carcinoma reveals the importance of ABCB6 in regulating ferroptosis

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

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Sestrin2 Expression Has Regulatory Properties and Prognostic Value in Lung Cancer

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Near Infrared‐Activatable Platinum‐Decorated Gold Nanostars for Synergistic Photothermal/Ferroptotic Therapy in Combating Cancer Drug Resistance

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Emerging roles of ferroptosis in liver pathophysiology

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Ferrostatin-1 protects auditory hair cells from cisplatin-induced ototoxicity in vitro and in vivo

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Bioactive metal-containing nanomaterials for ferroptotic cancer therapy

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Regulated Necrotic Cell Death in Alternative Tumor Therapeutic Strategies

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A New Approach in Cancer Treatment: Discovery of Chlorido[N,N′-disalicylidene-1,2-phenylenediamine]iron(III) Complexes as Ferroptosis Inducers

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Recent Progress in Ferroptosis Inducers for Cancer Therapy

Chen Liang, Xinglin Zhang, Mengsu Yang, Xiaochen Dong

Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule

Fei Deng, Isha Sharma, Yingbo Dai, Ming Yang, Yashpal S. Kanwar

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STYK1/NOK correlates with ferroptosis in non-small cell lung carcinoma

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Erastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer

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The role of ferroptosis in digestive system cancer (Review)

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Potential mechanism of ferroptosis in pancreatic cancer (Review)

Gang Chen, Guangqi Guo, Xiaodong Zhou, Hongxia Chen

Stearoyl-CoA Desaturase 1 Protects Ovarian Cancer Cells from Ferroptotic Cell Death

Lia Tesfay, Bibbin T. Paul, Anna Konstorum, Zhiyong Deng, Anderson O. Cox, Jingyun Lee, Cristina M. Furdui, Poornima Hegde, Frank M. Torti, Suzy V. Torti

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Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System

Jan Lewerenz, Gamze Ates, Axel Methner, Marcus Conrad, Pamela Maher

Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review

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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I. Bush, Marcus Conrad, Scott J. Dixon, Simone Fulda, Sergio Gascón, Stavroula K. Hatzios, Valerian E. Kagan, Kay Noel, Xuejun Jiang, Andreas Linkermann, Maureen E. Murphy, Michael Overh