Cancer Research and Treatment

Statins in the Cause and Prevention of Cancer: Confounding by Indication and Mediation by Rhabdomyolysis and Phosphate Toxicity

Journal of Cardiovascular Development and Disease.2024; 11(9): 296. CrossRef

Unraveling lipid metabolism reprogramming for overcoming drug resistance in melanoma

Biochemical Pharmacology.2024; 223: 116122. CrossRef

Cardiovascular/anti‐inflammatory drugs repurposed for treating or preventing cancer: A systematic review and meta‐analysis of randomized trials

The preventative effects of statin on lung cancer development in patients with idiopathic pulmonary fibrosis using the National Health Insurance Service Database in Korea

Yoo Jung Lee, Nayoon Kang, Junghyun Nam, Eung Gu Lee, Jiwon Ryoo, Soon Seog Kwon, Yong Hyun Kim, Hye Seon Kang, Tsai-Ching Hsu

DHCR24 in Tumor Diagnosis and Treatment: A Comprehensive Review

Technology in Cancer Research & Treatment.2024;[Epub] CrossRef

The effects of statins in patients with advanced-stage cancers - a systematic review and meta-analysis

Qiang Zhou, Zhihua Jiao, Yuxi Liu, Peter N. Devreotes, Zhenyu Zhang

Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients

Claes R. Andersson, Jiawei Ye, Kristin Blom, Mårten Fryknäs, Rolf Larsson, Peter Nygren

New insights into the therapeutic potentials of statins in cancer

Chengyu Liu, Hong Chen, Bicheng Hu, Jiajian Shi, Yuchen Chen, Kun Huang

Functional significance of cholesterol metabolism in cancer: from threat to treatment

Mingming Xiao, Jin Xu, Wei Wang, Bo Zhang, Jiang Liu, Jialin Li, Hang Xu, Yingjun Zhao, Xianjun Yu, Si Shi

Experimental & Molecular Medicine.2023; 55(9): 1982. CrossRef

Simvastatin Enhanced Anti-tumor Effects of Bevacizumab against Lung Adenocarcinoma A549 Cells via Abating HIF-1α-Wnt/β-Catenin Signaling Pathway

Xin Tu, Jian Zhang, Wei Yuan, Xia Wu, Zhi Xu, Cuo Qing

Anti-Cancer Agents in Medicinal Chemistry.2023; 23(19): 2083. CrossRef

Lipoproteins and cancer: The role of HDL-C, LDL-C, and cholesterol-lowering drugs

Biochemical Pharmacology.2022; 196: 114654. CrossRef

Beyond Lipid-Lowering: Effects of Statins on Cardiovascular and Cerebrovascular Diseases and Cancer

Yoichi Morofuji, Shinsuke Nakagawa, Kenta Ujifuku, Takashi Fujimoto, Kaishi Otsuka, Masami Niwa, Keisuke Tsutsumi

Reprogramming of Lipid Metabolism in Lung Cancer: An Overview with Focus on EGFR-Mutated Non-Small Cell Lung Cancer

Kamal Eltayeb, Silvia La Monica, Marcello Tiseo, Roberta Alfieri, Claudia Fumarola

Effect of Statins on Lung Cancer Molecular Pathways: A Possible Therapeutic Role

Gianmarco Marcianò, Caterina Palleria, Alessandro Casarella, Vincenzo Rania, Emanuele Basile, Luca Catarisano, Cristina Vocca, Luigi Bianco, Corrado Pelaia, Erika Cione, Bruno D’Agostino, Rita Citraro, Giovambattista De Sarro, Luca Gallelli

The effects of epithelial–mesenchymal transitions in COPD induced by cigarette smoke: an update

Xiaoshan Su, Weijing Wu, Zhixing Zhu, Xiaoping Lin, Yiming Zeng

Scientific Research Directions on the Histopathology and Immunohistochemistry of the Cutaneous Squamous Cell Carcinoma: A Scientometric Study

Iuliu Gabriel Cocuz, Maria Elena Cocuz, Angela Repanovici, Adrian-Horațiu Sabău, Raluca Niculescu, Andreea-Cătălina Tinca, Vlad Vunvulea, Corina Eugenia Budin, Andreea Raluca Szoke, Maria Cătălina Popelea, Raluca Moraru, Titiana Cornelia Cotoi, Ovidiu Sim

Xueli Bian, Rui Liu, Ying Meng, Dongming Xing, Daqian Xu, Zhimin Lu

Journal of Experimental Medicine.2021;[Epub] CrossRef

Simvastatin-romidepsin combination kills bladder cancer cells synergistically

Kazuki Okubo, Kosuke Miyai, Kimi Kato, Takako Asano, Akinori Sato

Translational Oncology.2021; 14(9): 101154. CrossRef

Statins Decrease Programmed Death-Ligand 1 (PD-L1) by Inhibiting AKT and β-Catenin Signaling

Woo-Jin Lim, Mingyu Lee, Yerin Oh, Xue-Quan Fang, Sujin Lee, Chang-Hoon Lim, Jooho Park, Ji-Hong Lim

ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells

Jillian Hattaway Luttman, Jacob P. Hoj, Kevin H. Lin, Jiaxing Lin, Jing Jin Gu, Clay Rouse, Amanda G. Nichols, Nancie J. MacIver, Kris C. Wood, Ann Marie Pendergast

Adjuvant statin therapy for oesophageal adenocarcinoma: the STAT-ROC feasibility study

L. Alexandre, A. B. Clark, S. Walton, M. P. Lewis, B. Kumar, E. C. Cheong, H. Warren, S. S. Kadirkamanathan, S. L. Parsons, S. M. Dresner, E. Sims, M. Jones, M. Hammond, M. Flather, Y. K. Loke, A. M. Swart, A. R. Hart

Whether statin use improves the survival of patients with glioblastoma?

Yonglin Xie, Qin Lu, Cameron Lenahan, Shuxu Yang, Daoyang Zhou, Xuchen Qi

Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells

Kazuki Okubo, Makoto Isono, Kosuke Miyai, Takako Asano, Akinori Sato

Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage?

Paolo Gelosa, Laura Castiglioni, Marina Camera, Luigi Sironi

Biochemical Pharmacology.2020; 177: 113895. CrossRef

Attenuation of the pro-inflammatory signature of lung cancer-derived mesenchymal stromal cells by statins

Sabine Galland, Patricia Martin, Giulia Fregni, Igor Letovanec, Ivan Stamenkovic

Efficacy and safety profile of statins in patients with cancer: a systematic review of randomised controlled trials

European Journal of Clinical Pharmacology.2020; 76(12): 1639. CrossRef

Statins as Anticancer Agents in the Era of Precision Medicine

Joseph Longo, Jenna E. van Leeuwen, Mohamad Elbaz, Emily Branchard, Linda Z. Penn

Clinical Cancer Research.2020; 26(22): 5791. CrossRef

Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway

Sheng Zhou, Huanji Xu, Qiulin Tang, Hongwei Xia, Feng Bi

Molecular Cancer Therapeutics.2020; 19(1): 135. CrossRef

Diverse Stakeholders of Tumor Metabolism: An Appraisal of the Emerging Approach of Multifaceted Metabolic Targeting by 3-Bromopyruvate

Saveg Yadav, Shrish Kumar Pandey, Yugal Goel, Mithlesh Kumar Temre, Sukh Mahendra Singh

Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis

Cheng-Wei Chou, Ching-Heng Lin, Tzu-Hung Hsiao, Chia-Chien Lo, Chih-Ying Hsieh, Cheng-Chung Huang, Yuh-Pyng Sher

Drug Repurposing of Metabolic Agents in Malignant Glioma

International Journal of Molecular Sciences.2018; 19(9): 2768. CrossRef

The Effect of Statin Added to Systemic Anticancer Therapy: A Meta-Analysis of Randomized, Controlled Trials

Journal of Clinical Medicine.2018; 7(10): 325. CrossRef

Statin therapy in the treatment of active cancer: A systematic review and meta-analysis of randomized controlled trials

Mohammed A. M. Farooqi, Nikita Malhotra, Som D. Mukherjee, Stephanie Sanger, Sukhbinder K. Dhesy-Thind, Peter Ellis, Darryl P. Leong, Robert M. Lafrenie

Synergistic effect of receptor-interacting protein 140 and simvastatin on the inhibition of proliferation and survival of hepatocellular carcinoma cells

Kun Xia, Panpan Zhang, Jian Hu, Huan Hou, Mingdi Xiong, Junping Xiong, Nianlong Yan