Cancer Research and Treatment

Tumor microenvironment responded naturally extracted FOF1-ATPase loaded chromatophores for antitumor therapy

Weiyong Hong, Bang Lou, Ying Gao, Hui Zhao, Sanjun Ying, Saicheng Yang, Hanbing Li, Qingliang Yang, Gensheng Yang

International Journal of Biological Macromolecules.2023; 230: 123127. CrossRef

MITF Downregulation Induces Death in Human Mast Cell Leukemia Cells and Impairs IgE-Dependent Degranulation

Elizabeth Proaño-Pérez, Laia Ollé, Yanru Guo, Cristina Aparicio, Mario Guerrero, Rosa Muñoz-Cano, Margarita Martin

International Journal of Molecular Sciences.2023; 24(4): 3515. CrossRef

Autophagy in BRAF-mutant cutaneous melanoma: recent advances and therapeutic perspective

Elisabetta Fratta, Giorgio Giurato, Roberto Guerrieri, Francesca Colizzi, Jessica Dal Col, Alessandro Weisz, Agostino Steffan, Barbara Montico

BRAF Mutations in Melanoma: Biological Aspects, Therapeutic Implications, and Circulating Biomarkers

Giorgia Castellani, Mariachiara Buccarelli, Maria Beatrice Arasi, Stefania Rossi, Maria Elena Pisanu, Maria Bellenghi, Carla Lintas, Claudio Tabolacci

METTL3 promotes non-small-cell lung cancer growth and metastasis by inhibiting FDX1 through copper death-associated pri-miR-21-5p maturation

A Review on the Role of miR-1246 in the Pathoetiology of Different Cancers

Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Mohammad Samadian

Frontiers in Molecular Biosciences.2022;[Epub] CrossRef

Circulating miR-1246 and miR-485-3p as Promising Biomarkers of Clinical Response and Outcome in Melanoma Patients Treated with Targeted Therapy

Lauretta Levati, Cristian Bassi, Simona Mastroeni, Laura Lupini, Gian Carlo Antonini Cappellini, Laura Bonmassar, Ester Alvino, Simona Caporali, Pedro Miguel Lacal, Maria Grazia Narducci, Ivan Molineris, Federica De Galitiis, Massimo Negrini, Giandomenico

Paradoxical downregulation of LPAR3 exerts tumor-promoting activity through autophagy induction in Ras-transformed cells

SH3BP2 Silencing Increases miRNAs Targeting ETV1 and Microphthalmia-Associated Transcription Factor, Decreasing the Proliferation of Gastrointestinal Stromal Tumors

Elizabeth Proaño-Pérez, Eva Serrano-Candelas, Cindy Mancia, Arnau Navinés-Ferrer, Mario Guerrero, Margarita Martin

Carfilzomib in Combination with Bortezomib Enhances Apoptotic Cell Death in B16-F1 Melanoma Cells

Min Seung Lee, So Hyun Lim, Ah-Ran Yu, Chi Yeon Hwang, Insug Kang, Eui-Ju Yeo

Resistance to Molecularly Targeted Therapies in Melanoma

Meet Patel, Adam Eckburg, Shahina Gantiwala, Zachary Hart, Joshua Dein, Katie Lam, Neelu Puri

Learning from Embryogenesis—A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development

Lisa Linck-Paulus, Lisa Lämmerhirt, Daniel Völler, Katharina Meyer, Julia C. Engelmann, Rainer Spang, Norbert Eichner, Gunter Meister, Silke Kuphal, Anja Katrin Bosserhoff

Journal of Clinical Medicine.2021; 10(11): 2259. CrossRef

METTL3 promotes the initiation and metastasis of ovarian cancer by inhibiting CCNG2 expression via promoting the maturation of pri-microRNA-1246

Xuehan Bi, Xiao Lv, Dajiang Liu, Hongtao Guo, Guang Yao, Lijuan Wang, Xiaolei Liang, Yongxiu Yang

Choosing The Right Animal Model for Renal Cancer Research

Paweł Sobczuk, Anna Brodziak, Mohammed Imran Khan, Stuti Chhabra, Michał Fiedorowicz, Marlena Wełniak-Kamińska, Kamil Synoradzki, Ewa Bartnik, Agnieszka Cudnoch-Jędrzejewska, Anna M. Czarnecka

Translational Oncology.2020; 13(3): 100745. CrossRef

Circulating microRNAs as biomarkers for early diagnosis of cutaneous melanoma

Sara Carpi, Beatrice Polini, Stefano Fogli, Adriano Podestà, Erkko Ylösmäki, Vincenzo Cerullo, Antonella Romanini, Paola Nieri

Expert Review of Molecular Diagnostics.2020; 20(1): 19. CrossRef

Autophagy inhibition in 3T3-L1 adipocytes breaks the crosstalk with tumor cells by suppression of adipokine production

Animal Cells and Systems.2020; 24(1): 17. CrossRef

Roles of S100 family members in drug resistance in tumors: Status and prospects

Xin Hua, Hongming Zhang, Jinfang Jia, Shanshan Chen, Yue Sun, Xiaoli Zhu

Biomedicine & Pharmacotherapy.2020; 127: 110156. CrossRef

MicroRNAs as Key Players in Melanoma Cell Resistance to MAPK and Immune Checkpoint Inhibitors

Maria Letizia Motti, Michele Minopoli, Gioconda Di Carluccio, Paolo Antonio Ascierto, Maria Vincenza Carriero

International Journal of Molecular Sciences.2020; 21(12): 4544. CrossRef

Circulating miRNAs in Small Extracellular Vesicles Secreted by a Human Melanoma Xenograft in Mouse Brains

Loredana Guglielmi, Marta Nardella, Carla Musa, Ingrid Cifola, Manuela Porru, Beatrice Cardinali, Ilaria Iannetti, Chiara Di Pietro, Giulia Bolasco, Valentina Palmieri, Laura Vilardo, Nicolò Panini, Fabrizio Bonaventura, Massimiliano Papi, Ferdinando Scav

MiR‐1246 promotes anti‐apoptotic effect of mini‐αA in oxidative stress‐induced apoptosis in retinal pigment epithelial cells

Qianyin Chen, Huimin Lin, Xuan Deng, Shengnan Li, Jinglin Zhang

Clinical & Experimental Ophthalmology.2020; 48(5): 682. CrossRef

Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review

Ilaria Proietti, Nevena Skroza, Nicoletta Bernardini, Ersilia Tolino, Veronica Balduzzi, Anna Marchesiello, Simone Michelini, Salvatore Volpe, Alessandra Mambrin, Giorgio Mangino, Giovanna Romeo, Patrizia Maddalena, Catherine Rees, Concetta Potenza

The potential of BRAF-associated non-coding RNA as a therapeutic target in melanoma

Luigi Fattore, Rita Mancini, Paolo Antonio Ascierto, Gennaro Ciliberto

Expert Opinion on Therapeutic Targets.2019; 23(1): 53. CrossRef

A plasma microRNA biomarker of melanoma as a personalised assessment of treatment response

Ryan K. van Laar, Mitchel T. Lincoln, Barton J. van Laar

A three plasma microRNA signature for papillary thyroid carcinoma diagnosis in Chinese patients

Zhiyan Wang, Jinru Lv, Xuan Zou, Zebo Huang, Huo Zhang, Qingxie Liu, Lin Jiang, Xin Zhou, Wei Zhu

The origin of exosomal miR-1246 in human cancer cells

Yi-Fan Xu, Bethany N. Hannafon, Ujjwol Khatri, Amy Gin, Wei-Qun Ding

Differential Gene Expression Common to Acquired and Intrinsic Resistance to BRAF Inhibitor Revealed by RNA-Seq Analysis

Jun-Ho Ahn, Sung-Hee Hwang, Hyun-Soo Cho, Michael Lee

Biomolecules & Therapeutics.2019; 27(3): 302. CrossRef

Seminars in Cancer Biology.2019; 59: 208. CrossRef

miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A

Simona Caporali, Adriana Amaro, Lauretta Levati, Ester Alvino, Pedro Miguel Lacal, Simona Mastroeni, Federica Ruffini, Laura Bonmassar, Gian Carlo Antonini Cappellini, Nadia Felli, Alessandra Carè, Ulrich Pfeffer, Stefania D’Atri

Journal of Experimental & Clinical Cancer Research.2019;[Epub] CrossRef

MicroRNA-1246 regulates the radio-sensitizing effect of curcumin in bladder cancer cells via activating P53

Ran Xu, Huabing Li, Shuiqing Wu, Jian Qu, Haiyan Yuan, Yangang Zhou, Qiong Lu

International Urology and Nephrology.2019; 51(10): 1771. CrossRef

The “-OMICS” facet of melanoma: Heterogeneity of genomic, proteomic and metabolomic biomarkers

Seminars in Cancer Biology.2019; 59: 165. CrossRef

Upregulation of S100A9 contributes to the acquired resistance to BRAF inhibitors

Targeting CDC7 sensitizes resistance melanoma cells to BRAFV600E-specific inhibitor by blocking the CDC7/MCM2-7 pathway

Shaimaa A. Gad, Hamdy E. A. Ali, Rofaida Gaballa, Rania M. Abdelsalam, Mourad Zerfaoui, Hamed I. Ali, Salwa H. Salama, Sanaa A. Kenawy, Emad Kandil, Zakaria Y. Abd Elmageed

The Role of Autophagy in the Resistance to BRAF Inhibition in BRAF-Mutated Melanoma

Targeting signal-transducer-and-activator-of-transcription 3 sensitizes human cutaneous melanoma cells to BRAF inhibitor

Xiaohui Wang, Huajun Qu, Yinghe Dong, Guozhi Wang, Yuchen Zhen, Linxia Zhang

Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4

Li-Jun Mo, Man Song, Qiao-Hua Huang, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Bo Huang, Rui-Xue Huang, Ping-Kun Zhou

British Journal of Cancer.2018; 119(4): 492. CrossRef

An oasis in the desert of cancer chemotherapeutic resistance: The enlightenment from reciprocal crosstalk between signaling pathways of UPR and autophagy in cancers

Biomedicine & Pharmacotherapy.2017; 92: 972. CrossRef