Cancer Research and Treatment

Tumor-derived exosomal miR-1247-3p promotes angiogenesis in bladder cancer by targeting FOXO1

Cancer Biology & Therapy.2024;[Epub] CrossRef

Sirt6-Mediated Cell Death Associated with Sirt1 Suppression in Gastric Cancer

Ji Hyun Seo, Somi Ryu, So Young Cheon, Seong-Jun Lee, Seong-Jun Won, Chae Dong Yim, Hyun-Jin Lee, Young-Sool Hah, Jung Je Park

Insertion/deletions within the bovine FoxO1 gene and their association analysis with growth traits in three Chinese cattle breeds

Kunpeng Liu, Ao Qi, Wenxiu Ru, Xiaojun Jiang, Hui Cao, Xianyong Lan, Yongzhen Huang, Chuzhao Lei, Xiuzhu Sun, Hong Chen

Animal Biotechnology.2023; 34(7): 2051. CrossRef

Hepatocellular carcinoma-derived FOXO1 inhibits tumor progression by suppressing IL-6 secretion from macrophages

Xiao Cui, Huiyong Zhao, Sheng Wei, Qiang Du, Kun Dong, Yihe Yan, David. A Geller

Tetrahedral Framework Nucleic Acids Promote Senile Osteoporotic Fracture Repair by Enhancing Osteogenesis and Angiogenesis of Callus

Li-Nan Liu, Pei Hu, Yao Liu, Yue Sun, Zhong-Ming Li, Jia-Zhuang Xu, En Luo

ACS Applied Materials & Interfaces.2023; 15(21): 25403. CrossRef

LITAF inhibits colorectal cancer stemness and metastatic behavior by regulating FOXO1-mediated SIRT1 expression

Jiao Guan, Zheng-Yun Zhang, Jian-Hua Sun, Xin-Ping Wang, Zun-Qiang Zhou, Lei Qin

Clinical & Experimental Metastasis.2023; 40(4): 309. CrossRef

miR-376a inhibits glioma proliferation and angiogenesis by regulating YAP1/VEGF signalling via targeting of SIRT1

Translational Oncology.2022; 15(1): 101270. CrossRef

Cytochalasin Q exerts anti-melanoma effect by inhibiting creatine kinase B

Yi Lu, Peng Zhang, Hongdan Chen, Qingyi Tong, Jia Wang, Qing Li, Cheng Tian, Jian Yang, Senlin Li, Zijun Zhang, Huimin Yuan, Ming Xiang

Toxicology and Applied Pharmacology.2022; 441: 115971. CrossRef

The HIF-1α as a Potent Inducer of the Hallmarks in Gastric Cancer

The FOXO family of transcription factors: key molecular players in gastric cancer

Ying Liu, Xiang Ao, Yi Jia, Xiaoge Li, Yu Wang, Jianxun Wang

Journal of Molecular Medicine.2022; 100(7): 997. CrossRef

Exosomal miR-27b-3p Derived from Hypoxic Cardiac Microvascular Endothelial Cells Alleviates Rat Myocardial Ischemia/Reperfusion Injury through Inhibiting Oxidative Stress-Induced Pyroptosis via Foxo1/GSDMD Signaling

Baojian Zhang, Chao Sun, Yaozhong Liu, Fan Bai, Tao Tu, Qiming Liu, Tian Li

Oxidative Medicine and Cellular Longevity.2022; 2022: 1. CrossRef

Whole-Exome Sequencing Reveals Pathogenic SIRT1 Variant in Brain Arteriovenous Malformation: A Case Report

Kymbat Mukhtarova, Elena Zholdybayeva, Ulykbek Kairov, Ilyas Akhmetollayev, Chingiz Nurimanov, Marat Kulmirzayev, Yerbol Makhambetov, Yerlan Ramankulov

Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target?

Amandine Badie, Christian Gaiddon, Georg Mellitzer

Sirtuins (SIRTs) As a Novel Target in Gastric Cancer

Agata Poniewierska-Baran, Paulina Warias, Katarzyna Zgutka

International Journal of Molecular Sciences.2022; 23(23): 15119. CrossRef

Cdc20 induces the radioresistance of bladder cancer cells by targeting FoxO1 degradation

Lixia Wang, Chuanlai Yang, Man Chu, Zhi-wei Wang, Boxin Xue

Treatment Strategies of Gastric Cancer—Molecular Targets for Anti-angiogenic Therapy: a State-of-the-art Review

Magdalena Tyczyńska, Paweł Kędzierawski, Kaja Karakuła, Jacek Januszewski, Krzysztof Kozak, Monika Sitarz, Alicja Forma

Journal of Gastrointestinal Cancer.2021; 52(2): 476. CrossRef

Clinicopathological Significances of Tumor–Stroma Ratio (TSR) in Colorectal Cancers: Prognostic Implication of TSR Compared to Hypoxia-Inducible Factor-1α Expression and Microvessel Density

Guhyun Kang, Jung-Soo Pyo, Nae-Yu Kim, Dong-Wook Kang

Current Oncology.2021; 28(2): 1314. CrossRef

Diverse roles of FOXO family members in gastric cancer

Yu-Han Chen, Chun-Lan Li, Wen-Jia Chen, Jing Liu, Hua-Tao Wu

World Journal of Gastrointestinal Oncology.2021; 13(10): 1367. CrossRef

Sirtuin-1 and Its Relevance in Vascular Calcification

Chien-Lin Lu, Min-Tser Liao, Yi-Chou Hou, Yu-Wei Fang, Cai-Mei Zheng, Wen-Chih Liu, Chia-Ter Chao, Kuo-Cheng Lu, Yee-Yung Ng

International Journal of Molecular Sciences.2020; 21(5): 1593. CrossRef

Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis

Mohd Farhan, Marta Silva, Xing Xingan, Yu Huang, Wenhua Zheng

Clinicopathological significance and angiogenic role of the constitutive phosphorylation of the FOXO1 transcription factor in colorectal cancer

Pathology - Research and Practice.2020; 216(11): 153150. CrossRef

Exosomal miR-183-5p promotes angiogenesis in colorectal cancer by regulation of FOXO1

Anquan Shang, Xuan Wang, Chenzheng Gu, Wenfang Liu, Junjun Sun, Bingjie Zeng, Chen Chen, Ping Ji, Junlu Wu, Wenqiang Quan, Yiwen Yao, Weiwei Wang, Zujun Sun, Dong Li

Hypoxia-Inducible Lysine Methyltransferases: G9a and GLP Hypoxic Regulation, Non-histone Substrate Modification, and Pathological Relevance

Anand Chopra, William C. Cho, William G. Willmore, Kyle K. Biggar

Frontiers in Genetics.2020;[Epub] CrossRef

Interconnection between Metabolism and Cell Cycle in Cancer

Philippe Icard, Ludovic Fournel, Zherui Wu, Marco Alifano, Hubert Lincet

Trends in Biochemical Sciences.2019; 44(6): 490. CrossRef

Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation

Integrative Cancer Therapies.2019; 18: 153473541984637. CrossRef

Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications

Wei Sun, Bing Wang, Xing-Long Qu, Bi-Qiang Zheng, Wen-Ding Huang, Zheng-Wang Sun, Chun-Meng Wang, Yong Chen

Oncogenic USP22 supports gastric cancer growth and metastasis by activating c-Myc/NAMPT/SIRT1-dependent FOXO1 and YAP signaling

Hongxia Liu, Ningning Liu, Yali Zhao, Xiaoshan Zhu, Changsong Wang, Qinqin Liu, Chunfang Gao, Xusheng Zhao, Juntang Li

FOXO1: Another avenue for treating digestive malignancy?

Feiyu Shi, Tian Li, Zhi Liu, Kai Qu, Chengxin Shi, Yaguang Li, Qian Qin, Liang Cheng, Xin Jin, Tianyu Yu, Wencheng Di, Jianwen Que, Hongping Xia, Junjun She

Seminars in Cancer Biology.2018; 50: 124. CrossRef

Homeostatic interplay between FoxO proteins and ER proteostasis in cancer and other diseases

Matías González-Quiroz, Hery Urra, Celia María Limia, Claudio Hetz

Seminars in Cancer Biology.2018; 50: 42. CrossRef

Deciphering the roles of FOXO1 in human neoplasms

Shuai Jiang, Tian Li, Zhi Yang, Wei Hu, Yang Yang

International Journal of Cancer.2018; 143(7): 1560. CrossRef

Sinomenine Induces G1-Phase Cell Cycle Arrest and Apoptosis in Malignant Glioma Cells Via Downregulation of Sirtuin 1 and Induction of p53 Acetylation

Xiaoyan He, Mayinur Maimaiti, Yan Jiao, Xuegang Meng, Hongyan Li

Technology in Cancer Research & Treatment.2018; 17: 153303461877030. CrossRef

Impact of curcumin on sirtuins: A review

Elham Zendedel, Alexandra E Butler, Stephen L Atkin, Amirhossein Sahebkar

Journal of Cellular Biochemistry.2018; 119(12): 10291. CrossRef

Downregulation of microRNA‑660 inhibits cell proliferation and invasion in osteosarcoma by directly targeting forkhead box O1

Peng Zhang, Haifeng Gao, Qing Li, Xinlei Chen, Xifa Wu

Molecular Medicine Reports.2018;[Epub] CrossRef

miR-101 suppresses HBV replication and expression by targeting FOXO1 in hepatoma carcinoma cell lines

Biochemical and Biophysical Research Communications.2017; 487(1): 167. CrossRef

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition

Tianxiu Dong, Yu Zhang, Yaodong Chen, Pengfei Liu, Tingting An, Jiuwei Zhang, Haichao Yang, Wenjing Zhu, Xiuhua Yang

c-Jun N-terminal kinase activation has a prognostic implication and is negatively associated with FOXO1 activation in gastric cancer

Youngsun Choi, Jinju Park, Yiseul Choi, Young San Ko, Da-Ae Yu, Younghoon Kim, Jung-Soo Pyo, Bo Gun Jang, Min A. Kim, Woo Ho Kim, Byung Lan Lee

BMC Gastroenterology.2016;[Epub] CrossRef

Transcriptional repression of FOXO1 by KLF4 contributes to glioma progression

Guodong Tang, Dingyang Liu, Gelei Xiao, Qing Liu, Jian Yuan

Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression

Young San Ko, Sung Jin Cho, Jinju Park, Younghoon Kim, Yong Joon Choi, Jung-Soo Pyo, Bo Gun Jang, Jong-Wan Park, Woo Ho Kim, Byung Lan Lee

British Journal of Cancer.2015; 113(8): 1186. CrossRef