Cancer Research and Treatment

Autophagy in cancer resistance to paclitaxel: Development of combination strategies

Jan Škubník, Vladimíra Svobodová Pavlíčková, Tomáš Ruml, Silvie Rimpelová

Biomedicine & Pharmacotherapy.2023; 161: 114458. CrossRef

Advances in autophagy modulation of natural products in cervical cancer

Journal of Ethnopharmacology.2023; 314: 116575. CrossRef

Chloroquine Sensitizes Esophageal Carcinoma EC109 Cells to Paclitaxel by Inhibiting Autophagy

Zichun Yuan, Jiajing Cai, Qin Du, Qiang Ma, Lei Xu, Yan Cai, Xiaowu Zhong, Xiaolan Guo

Critical Reviews in Eukaryotic Gene Expression.2023; 33(6): 43. CrossRef

New sight into interaction between endoplasmic reticulum stress and autophagy induced by vanadium in duck renal tubule epithelial cells

Li Wang, Yueying Pan, Fan Yang, Xiaowang Guo, Junjun Peng, Xiaoyu Wang, Yukun Fang, Jing Chen, Xin Yi, Huabin Cao, Guoliang Hu

Chemico-Biological Interactions.2022; 362: 109981. CrossRef

Cisplatin and paclitaxel-loaded liposomes induced cervical cancer (HeLa) cell death with multiple copies of human papillomavirus by apoptosis and decreased their cytotoxic effect on non-tumor cells

Paulo Emilio Feuser, Ellen De Pieri, Maria Eduarda Oliveira, Arthur Poester Cordeiro, Rodrigo Cercena, Pedro Henrique Hermes de Araújo, Alexandre Gonçalves Dal Bó, Ricardo Andrez Machado-de-Ávila

Journal of Drug Delivery Science and Technology.2022; 73: 103457. CrossRef

Mechanisms of cancer cell death induction by paclitaxel: an updated review

Shuang Zhao, Yufei Tang, Ruohan Wang, Masoud Najafi

An Updated Review on Implications of Autophagy and Apoptosis in Tumorigenesis: Possible Alterations in Autophagy through Engineered Nanomaterials and Their Importance in Cancer Therapy

Habib Ghaznavi, Milad Shirvaliloo, Amir Zarebkohan, Zinat Shams, Fatemeh Radnia, Zahra Bahmanpour, Saman Sargazi, Ramin Saravani, Sakine Shirvalilou, Omolbanin Shahraki, Sheida Shahraki, Ziba Nazarlou, Roghayeh Sheervalilou

Molecular Pharmacology.2021; 100(2): 119. CrossRef

Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux

Dong-lin Yang, Ya-jun Zhang, Liu-jun He, Chun-sheng Hu, Li-xia Gao, Jiu-hong Huang, Yan Tang, Jie Luo, Dian-yong Tang, Zhong-zhu Chen

Perturbation-Based Modeling Unveils the Autophagic Modulation of Chemosensitivity and Immunogenicity in Breast Cancer Cells

Isaac Quiros-Fernandez, Lucía Figueroa-Protti, Jorge L. Arias-Arias, Norman Brenes-Cordero, Francisco Siles, Javier Mora, Rodrigo Antonio Mora-Rodríguez

Enhanced efficacy of propranolol therapy for infantile hemangiomas based on a mesoporous silica nanoplatform through mediating autophagy dysfunction

Haiwei Wu, Xuan Wang, Hao Liang, Jiawei Zheng, Shengyun Huang, Dongsheng Zhang

Loss of tumor susceptibility gene 101 (TSG101) perturbs endoplasmic reticulum structure and function

Zenia Kaul, Debdatto Mookherjee, Subhrangshu Das, Debmita Chatterjee, Saikat Chakrabarti, Oishee Chakrabarti

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.2020; 1867(9): 118741. CrossRef

RSK2 protects human breast cancer cells under endoplasmic reticulum stress through activating AMPKα2-mediated autophagy

Lan-Ya Li, Xi-Sha Chen, Kuan-Song Wang, Yi-Di Guan, Xing-Cong Ren, Dong-Sheng Cao, Xin-Yuan Sun, Ao-Xue Li, Yong-Guang Tao, Yi Zhang, Ming-Zhu Yin, Xin-Luan Wang, Ming-Hua Wu, Jin-Ming Yang, Yan Cheng

New Insights into Therapy-Induced Progression of Cancer

Polina V. Shnaider, Olga M. Ivanova, Irina K. Malyants, Ksenia S. Anufrieva, Ilya A. Semenov, Marat S. Pavlyukov, Maria A. Lagarkova, Vadim M. Govorun, Victoria O. Shender

International Journal of Molecular Sciences.2020; 21(21): 7872. CrossRef

Kaempferol Induces Cell Death in A2780 Ovarian Cancer Cells and Increases Their Sensitivity to Cisplatin by Activation of Cytotoxic Endoplasmic Reticulum-Mediated Autophagy and Inhibition of Protein Kinase B

Attalla Farag El-Kott, A. A. Shati, M. A. Al-Kahtani, S. A. Alharbi

Targeted Codelivery of Docetaxel and Atg7 siRNA for Autophagy Inhibition and Pancreatic Cancer Treatment

Miaozun Zhang, Wei Zhang, Guping Tang, Hebin Wang, Min Wu, Weiming Yu, Zhenfeng Zhou, Yiping Mou, Xingang Liu

ACS Applied Bio Materials.2019; 2(3): 1168. CrossRef

An ATG5 knockout promotes paclitaxel resistance in v-Ha-ras-transformed NIH 3T3 cells

Seong Yun Eom, Sung-Hee Hwang, Hojin Yeom, Michael Lee

Biochemical and Biophysical Research Communications.2019; 513(1): 234. CrossRef

Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells

Jinmi Lee, Seok-Woo Hong, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee

Cell Stress and Chaperones.2019; 24(4): 825. CrossRef

Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer

Buse Cevatemre, Merve Erkısa, Nazlihan Aztopal, Didem Karakas, Pınar Alper, Chrisiida Tsimplouli, Evangelia Sereti, Konstantinos Dimas, Elif I. Ikitimur Armutak, Ebru Gurel Gurevin, Ayca Uvez, Mattia Mori, Simone Berardozzi, Cinzia Ingallina, Ilaria D’Acq

Pharmacological Research.2018; 129: 500. CrossRef

Chitosan-based zinc oxide nanoparticle for enhanced anticancer effect in cervical cancer: A physicochemical and biological perspective

Saudi Pharmaceutical Journal.2018; 26(2): 205. CrossRef

Pro-survival autophagy and cancer cell resistance to therapy

Cancer and Metastasis Reviews.2018; 37(4): 749. CrossRef

The Superior Antitumor Effect of Self-Assembled Paclitaxel Nanofilaments for Lung Cancer Cells

Mengyu He, Jiali Zhu, Na Yu, Hui Kong, Xiaoning Zeng, Weiping Xie, Huae Xu

Triptolide induces protective autophagy and apoptosis in human cervical cancer cells by downregulating Akt/mTOR activation

Upstream transcription factor 1 prompts malignancies of cervical cancer primarily by transcriptionally activating p65 expression

Wen Wang, Shujuan Yao, Hongjing Jiang, Jing Dong, Xiujuan Cui, Xiangyu Tian, Yanyan Guo, Shiqian Zhang

Experimental and Therapeutic Medicine.2018;[Epub] CrossRef

Autophagy inhibitors chloroquine and LY294002 enhance temozolomide cytotoxicity on cutaneous melanoma cell lines in vitro

Oxana O. Ryabaya, Andrey N. Inshakov, Angelina V. Egorova, Marina A. Emelyanova, Tatiana V. Nasedkina, Alexander S. Zasedatelev, Dmitry A. Khochenkov, Evgenia V. Stepanova

Endoplasmic Reticulum Stress and Homeostasis in Reproductive Physiology and Pathology

Elif Guzel, Sefa Arlier, Ozlem Guzeloglu-Kayisli, Mehmet Tabak, Tugba Ekiz, Nihan Semerci, Kellie Larsen, Frederick Schatz, Charles Lockwood, Umit Kayisli

International Journal of Molecular Sciences.2017; 18(4): 792. CrossRef

Sensitivity to antitubulin chemotherapeutics is potentiated by a photoactivable nanoliposome

Xiaobing Wang, Xiufang Liu, Yixiang Li, Pan Wang, Xiaolan Feng, Quanhong Liu, Fei Yan, Hairong Zheng

MicroRNA‐495 regulates starvation‐induced autophagy by targeting ATG3

Wen Li, Yue Yang, Xiaoyan Hou, Haixia Zhuang, Zijun Wu, Zhiyi Li, Runmin Guo, Hao Chen, Chunxia Lin, Wangtao Zhong, Yusen Chen, Keng Wu, Liangqing Zhang, Du Feng

ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways

Ryuji Oshima, Takafumi Hasegawa, Keiichi Tamai, Naoto Sugeno, Shun Yoshida, Junpei Kobayashi, Akio Kikuchi, Toru Baba, Akira Futatsugi, Ikuro Sato, Kennichi Satoh, Atsushi Takeda, Masashi Aoki, Nobuyuki Tanaka

The effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppression

Cheng-lin Luo, Yu-qiong Liu, Peng Wang, Chun-hua Song, Kai-juan Wang, Li-ping Dai, Jian-ying Zhang, Hua Ye

Biomedicine & Pharmacotherapy.2016; 82: 595. CrossRef

Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells

Baoqing Guo, Adam Tam, Stacey A. Santi, Amadeo M. Parissenti

Blocking autophagy enhances meloxicam lethality to hepatocellular carcinoma by promotion of endoplasmic reticulum stress

Jingtao Zhong, Xiaofeng Dong, Peng Xiu, Fuhai Wang, Ju Liu, Honglong Wei, Zongzhen Xu, Feng Liu, Tao Li, Jie Li

8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells

Cui Zhang, Yingnan Jiang, Jin Zhang, Jian Huang, Jinhui Wang

International Journal of Molecular Sciences.2015; 16(12): 14979. CrossRef