Cancer Research and Treatment

ORIGINAL ARTICLE 2024 January 18 Phase 1/2a Study of Rivoceranib, a Selective VEGFR-2 Angiogenesis Inhibitor, in Patients with Advanced Solid Tumors
Purpose This study aimed to report the results from an early-phase study of rivoceranib, an oral tyrosine kinase inhibitor highly selective for vascular endothelial growth factor receptor 2, in patients with advanced solid tumors. Materials and Methods In this open-label, singl...

ORIGINAL ARTICLE 2024 January 8 Analytical and Clinical Validation of a Highly Sensitive NGS-Based ctDNA Assay with Real-World Concordance in Non–Small Cell Lung Cancer
Purpose There have been needs to improve the sensitivity of liquid biopsy. This report aims to report the analytical and clinical validation of a next-generation sequencing (NGS)–based circulating tumor DNA (ctDNA) assay. Materials and Methods Analytical validation was conduct...

ORIGINAL ARTICLE 2024 January 30 Comparison of Clinicopathogenomic Features and Treatment Outcomes of EGFR and HER2 Exon 20 Insertion Mutations in Non–Small Cell Lung Cancer: Single-Institution Experience
Purpose Exon 20 insertion mutations (E20ins) in epidermal growth factor receptor (EGFR) or human epidermal growth factor receptor 2 (HER2) in non–small cell lung cancer (NSCLC) patients has become more important with emergence of novel agents targeting E20ins. Materials and Me...

Current Issue

Volume 56(3); Jul 2024

Volume 56(2); April 2024

Volume 56(1); January 2024

Editorial

699

Editor’s Note on Recent Journal Impact Factor of Cancer Research and Treatment

Yong Chan Ahn

Cancer Res Treat. 2024;56(3):699-699. Published online July 9, 2024 DOI: https://doi.org/10.4143/crt.2024.619

Web of Science 1 Crossref 1

Review Article

700

HER2-Low Breast Cancer: Now and in the Future

Sora Kang, Sung-Bae Kim

Cancer Res Treat. 2024;56(3):700-720. Published online January 30, 2024 DOI: https://doi.org/10.4143/crt.2023.1138

Special Article

721

Clinical Practice Recommendations for the Use of Next-Generation Sequencing in Patients with Solid Cancer: A Joint Report from KSMO and KSP

Miso Kim, Hyo Sup Shim, Sheehyun Kim, In Hee Lee, Jihun Kim, Shinkyo Yoon, Hyung-Don Kim, Inkeun Park, Jae Ho Jeong, Changhoon Yoo, Jaekyung Cheon, In-Ho Kim, Jieun Lee, Sook Hee Hong, Sehhoon Park, Hyun Ae Jung, Jin Won Kim, Han Jo Kim, Yongjun Cha, Sun Min Lim, Han Sang Kim, Choong-kun Lee, Jee Hung Kim, Sang Hoon Chun, Jina Yun, So Yeon Park, Hye Seung Lee, Yong Mee Cho, Soo Jeong Nam, Kiyong Na, Sun Och Yoon, Ahwon Lee, Kee-Taek Jang, Hongseok Yun, Sungyoung Lee, Jee Hyun Kim, Wan-Seop Kim

Cancer Res Treat. 2024;56(3):721-742. Published online November 29, 2023 DOI: https://doi.org/10.4143/crt.2023.1043

Original Articles

General

743

Phase 1/2a Study of Rivoceranib, a Selective VEGFR-2 Angiogenesis Inhibitor, in Patients with Advanced Solid Tumors

Yoon-Koo Kang, Min-Hee Ryu, Yong Sang Hong, Chang-Min Choi, Tae Won Kim, Baek-Yeol Ryoo, Jeong Eun Kim, John R. Weis, Rachel Kingsford, Cheol Hee Park, Seong Jang, Arlo McGinn, Theresa L. Werner, Sunil Sharma

Cancer Res Treat. 2024;56(3):743-750. Published online January 18, 2024 DOI: https://doi.org/10.4143/crt.2023.980

Lung and Thoracic cancer

751

Association of Immune-Related Adverse Events and the Efficacy of Anti–PD-(L)1 Monotherapy in Non–Small Cell Lung Cancer: Adjusting for Immortal-Time Bias

Ying Yu, Ning Chen, Sizhe Yu, Wanji Shen, Wanchen Zhai, Hui Li, Yun Fan

Cancer Res Treat. 2024;56(3):751-764. Published online January 2, 2024 DOI: https://doi.org/10.4143/crt.2023.1118

Web of Science 1

765

Analytical and Clinical Validation of a Highly Sensitive NGS-Based ctDNA Assay with Real-World Concordance in Non–Small Cell Lung Cancer

Hanbaek Yi, Jeonghwan Youk, Yoojoo Lim, Hanseong Roh, Dongsoo Kyung, Hwang-Phill Kim, Duhee Bang, Bhumsuk Keam, Tae-Min Kim, Miso Kim, Dong-Wan Kim, Tae-You Kim

Cancer Res Treat. 2024;56(3):765-773. Published online January 8, 2024 DOI: https://doi.org/10.4143/crt.2023.1294

Web of Science 2 Crossref 2

774

Comparison of Clinicopathogenomic Features and Treatment Outcomes of EGFR and HER2 Exon 20 Insertion Mutations in Non–Small Cell Lung Cancer: Single-Institution Experience

So Heun Lee, Hyehyun Jeong, Deok Hoon Kim, Se Jin Jang, Sang-We Kim, Shinkyo Yoon, Dae Ho Lee

Cancer Res Treat. 2024;56(3):774-784. Published online January 30, 2024 DOI: https://doi.org/10.4143/crt.2023.1177

785

Contribution of Enhanced Locoregional Control to Improved Overall Survival with Consolidative Durvalumab after Concurrent Chemoradiotherapy in Locally Advanced Non–Small Cell Lung Cancer: Insights from Real-World Data

Jeong Yun Jang, Si Yeol Song, Young Seob Shin, Ha Un Kim, Eun Kyung Choi, Sang-We Kim, Jae Cheol Lee, Dae Ho Lee, Chang-Min Choi, Shinkyo Yoon, Su Ssan Kim

Cancer Res Treat. 2024;56(3):785-794. Published online January 16, 2024 DOI: https://doi.org/10.4143/crt.2023.1014

Web of Science 1 Crossref 1

Breast cancer

795

Trastuzumab Biosimilar (HLX02), Pertuzumab Plus Chemotherapy in Patients with HER2-Positive Metastatic Breast Cancer after Progression of Trastuzumab: A Prospective, Phase II Study

Ruyan Zhang, Xiaoran Liu, Guohong Song, Yan Zhang, Huiping Li

Cancer Res Treat. 2024;56(3):795-801. Published online December 20, 2023 DOI: https://doi.org/10.4143/crt.2023.1151

802

Implementation of BRCA Test among Young Breast Cancer Patients in South Korea: A Nationwide Cohort Study

Yung-Huyn Hwang, Tae-Kyung Yoo, Sae Byul Lee, Jisun Kim, Beom Seok Ko, Hee Jeong Kim, Jong Won Lee, Byung Ho Son, Il Yong Chung

Cancer Res Treat. 2024;56(3):802-808. Published online February 19, 2024 DOI: https://doi.org/10.4143/crt.2023.1186

Gastrointestinal cancer

809

The Clinical Efficacy of Colorectal Cancer Patients with Pulmonary Oligometastases by Sterotactic Body Ablative Radiotherapy: A Meta-Analysis

Jae-Uk Jeong, Chai Hong Rim, Gyu Sang Yoo, Won Kyung Cho, Eui Kyu Chie, Yong Chan Ahn, Jong Hoon Lee, on behalf of Korean Oligometastasis Working Group, Korean Cancer Association

Cancer Res Treat. 2024;56(3):809-824. Published online December 14, 2023 DOI: https://doi.org/10.4143/crt.2023.920

825

The Persistence of Hypertriglyceridemia and the Risk of Early Onset Colorectal Cancer According to Tumor Subsites: A Nationwide Population-Based Study

Young Hoon Chang, Cheol Min Shin, Kyungdo Han, Jin Hyung Jung, Eun Hyo Jin, Joo Hyun Lim, Seung Joo Kang, Yoon Jin Choi, Hyuk Yoon, Young Soo Park, Nayoung Kim, Dong Ho Lee

Cancer Res Treat. 2024;56(3):825-837. Published online December 20, 2023 DOI: https://doi.org/10.4143/crt.2023.753

Web of Science 1 Crossref 1

838

Combined High-Dose Radiotherapy with Sequential Gemcitabine-Cisplatin Based Chemotherapy Increase the Resectability and Survival in Locally Advanced Unresectable Intrahepatic Cholangiocarcinoma: A Multi-institutional Cohort Study

Jung Ho Im, Jeong Il Yu, Tae Hyun Kim, Tae Gyu Kim, Jun Won Kim, Jinsil Seong

Cancer Res Treat. 2024;56(3):838-846. Published online January 2, 2024 DOI: https://doi.org/10.4143/crt.2023.886

847

Global Expanded Access Program for Pemigatinib in Patients with Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma and Fibroblast Growth Factor Receptor Gene Alterations

Anouk Lindley, Gerald Prager, Michael Bitzer, Timothy C. Burn, Christine F. Lihou, Elisabeth Croft

Cancer Res Treat. 2024;56(3):847-855. Published online February 7, 2024 DOI: https://doi.org/10.4143/crt.2023.1197

Web of Science 1 Crossref 1

Genitourinary cancer

856

Invasiveness of Upper Tract Urothelial Carcinoma: Clinical Significance and Integrative Diagnostic Strategy

Bokyung Ahn, Doeun Kim, Kye Jin Park, Ja-Min Park, Sun Young Yoon, Bumsik Hong, Yong Mee Cho, Deokhoon Kim

Cancer Res Treat. 2024;56(3):856-870. Published online December 18, 2023 DOI: https://doi.org/10.4143/crt.2023.1150

Web of Science 2 Crossref 2

871

Adjuvant Chemotherapy for Upper Tract Urothelial Carcinoma: A Real-World, Retrospective Study

Junho Lee, Sung Hee Lim, Jae Hoon Chung, Wan Song, Hyun Hwan Sung, Byong Chang Jeong, Se Hoon Park

Cancer Res Treat. 2024;56(3):871-876. Published online January 16, 2024 DOI: https://doi.org/10.4143/crt.2023.1226

Crossref 1

877

Single Early Intravesical Instillation of Epirubicin for Preventing Bladder Recurrence after Nephroureterectomy in Upper Urinary Tract Urothelial Carcinoma

Jong Hoon Lee, Chung Un Lee, Jae Hoon Chung, Wan Song, Minyong Kang, Hwang Gyun Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Hwan Sung

Cancer Res Treat. 2024;56(3):877-884. Published online January 17, 2024 DOI: https://doi.org/10.4143/crt.2023.1219

885

Bilateral Seminal Vesicle Invasion as a Strong Prognostic Indicator in T3b Prostate Cancer Patients Following Radical Prostatectomy: A Comprehensive, Multicenter, Long-term Follow-up Study

Jungyo Suh, In Gab Jeong, Hwang Gyun Jeon, Chang Wook Jeong, Sangchul Lee, Seong Soo Jeon, Seok-Soo Byun, Cheol Kwak, Hanjong Ahn

Cancer Res Treat. 2024;56(3):885-892. Published online January 5, 2024 DOI: https://doi.org/10.4143/crt.2023.1264

893

Neoadjuvant Cisplatin-Based Chemotherapy Followed by Selective Bladder Preservation Chemoradiotherapy in Muscle-Invasive Urothelial Carcinoma of the Bladder: Post Hoc Analysis of Two Prospective Studies

Sung Wook Cho, Sung Hee Lim, Ghee Young Kwon, Chan Kyo Kim, Won Park, Hongryull Pyo, Jae Hoon Chung, Wan Song, Hyun Hwan Sung, Byong Chang Jeong, Se Hoon Park

Cancer Res Treat. 2024;56(3):893-897. Published online February 15, 2024 DOI: https://doi.org/10.4143/crt.2024.015

Gynecologic cancer

898

Predicted Cervical Cancer Prevention: Impact of National HPV Vaccination Program on Young Women in South Korea

Kyeongmin Kwak, Seung-sik Hwang

Cancer Res Treat. 2024;56(3):898-908. Published online January 15, 2024 DOI: https://doi.org/10.4143/crt.2023.981

Pediatric cancer

909

The Role of Early and Delayed Surgery for Infants with Congenital Brain Tumors

Jong Seok Lee, Ji Yeoun Lee, Kyung Hyun Kim, Sung-Hye Park, Eun Jung Koh, Seung-Ki Kim, Ji Hoon Phi

Cancer Res Treat. 2024;56(3):909-919. Published online December 28, 2023 DOI: https://doi.org/10.4143/crt.2023.1174

Hematologic malignancy

920

Feasibility of Circulating Tumor DNA Analysis in Patients with Follicular Lymphoma

Sang Eun Yoon, Seung-Ho Shin, Dae Keun Nam, Junhun Cho, Won Seog Kim, Seok Jin Kim

Cancer Res Treat. 2024;56(3):920-935. Published online January 16, 2024 DOI: https://doi.org/10.4143/crt.2023.869

Crossref 1

936

Secondary Malignancies in Multiple Myeloma in Korean Patients: A Nationwide Population-Based Study

Boyoung Park, Eunyoung Lee, Junghyun Yoon, YoungJu Park, Hyeon-Seok Eom

Cancer Res Treat. 2024;56(3):936-944. Published online December 18, 2023 DOI: https://doi.org/10.4143/crt.2023.843

945

CD19-Specific CAR-T Cell Treatment of 115 Children and Young Adults with Acute B Lymphoblastic Leukemia: Long-term Follow-up

Yu Wang, Yu-juan Xue, Ying-xi Zuo, Yue-ping Jia, Ai-dong Lu, Hui-min Zeng, Le-ping Zhang

Cancer Res Treat. 2024;56(3):945-955. Published online February 13, 2024 DOI: https://doi.org/10.4143/crt.2023.1205

956

Nation-Wide Retrospective Analysis of Allogeneic Stem Cell Transplantation in Patients with Multiple Myeloma: A Study from Korean Multiple Myeloma Working Party (KMM1913)

Ho-Jin Shin, Do-Young Kim, Kihyun Kim, Chang-Ki Min, Je-Jung Lee, Yeung-Chul Mun, Won-Sik Lee, Sung-Nam Lim, Jin Seok Kim, Joon Ho Moon, Da Jung Kim, Soo-Mee Bang, Jong-Ho Won, Jae-Cheol Jo, Young Il Koh

Cancer Res Treat. 2024;56(3):956-966. Published online March 4, 2024 DOI: https://doi.org/10.4143/crt.2024.074

Case Report

967

Molecular and Treatment Characteristics of SMARCB1 or SMARCA4-Deficient Undifferentiated Tumor: Retrospective Case Series

Hyeon Gyu Kang, Jiwon Koh, Tae Min Kim, Doo Hee Han, Tae-Bin Won, Dong-Wan Kim, Dong-Young Kim, Bhumsuk Keam

Cancer Res Treat. 2024;56(3):967-971. Published online February 13, 2024 DOI: https://doi.org/10.4143/crt.2023.1308

Correspondence

972

Bridging the Gap between Trial Adverse Events and Real-World Data

Sang Hyuk Kim, Hyun Lee, Dong Won Park

Cancer Res Treat. 2024;56(3):972-973. Published online January 10, 2024 DOI: https://doi.org/10.4143/crt.2024.019