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Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014
Purpose This study presents the 2014 nationwide cancer statistics in Korea, including cancer incidence, survival, prevalence, and mortality. Materials and Methods Cancer incidence data from 1999 to 2014 was obtained from the Korea National Cancer Incidence Database and follo...
Expression of Myxovirus Resistance A (MxA) Is Associated with Tumor-Infiltrating Lymphocytes in Human Epidermal Growth Factor Receptor 2 (HER2)–Positive Breast Cancers
Purpose The prognostic significance of tumor-infiltrating lymphocytes (TILs) has been determined in breast cancers. Interferons can affect T-cell activity through direct and indirect mechanisms. Myxovirus resistance A (MxA) is an excellent marker of interferon activity. Here,we...
Blocking Interleukin-4 Receptor α Using Polyethylene Glycol Functionalized Superparamagnetic Iron Oxide Nanocarriers to Inhibit Breast Cancer Cell Proliferation
Purpose The specific targeting of interleukin-4 receptor α (IL4Rα) receptor offers a promising therapeutic approach for inhibition of tumor cell progression in breast cancer patients. In the current study, the in vitro efficacy of superparamagnetic iron oxide nanoparticles con...
Current Trends of Lung Cancer Surgery and Demographic and Social Factors Related to Changes in the Trends of Lung Cancer Surgery: An Analysis of the National Database from 2010 to 2014
Purpose We investigated current trends in lung cancer surgery and identified demographic and social factors related to changes in these trends. Materials and Methods We estimated the incidence of lung cancer surgery using a procedure code-based approach provided by the Health...
Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy
Purpose When integrating molecularly targeted compounds in radiotherapy, synergistic effects of the systemic agent and radiation may extend the limits of patient tolerance, increasing the demand for understanding the pathophysiological mechanisms of treatment toxicity. In this ...
Underexpression of HOXA11 Is Associated with Treatment Resistance and Poor Prognosis in Glioblastoma
Purpose Homeobox (HOX) genes are essential developmental regulators that should normally be in the silenced state in an adult brain. The aberrant expression of HOX genes has been associated with the prognosis of many cancer types, including glioblastoma (GBM). This study examin...
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Accepted articles are citable, though unedited, and E-pub version will be posted soon.

Original Articles
The Clinical Utilization of Radiation Therapy in Korea between 2011 and 2015
Young-Seok Seo, Mi-Sook Kim, Jin-Kyu Kang, Won-Il Jang, Hee Jin Kim, Chul Koo Cho, Hyung Jun Yoo, Eun Kyung Paik, Yu Jin Cha, Jae Sun Yoon
Received February 23, 2017     Accepted April 19, 2017     Published online April 25, 2017     DOI: https://doi.org/10.4143/crt.2017.096    
Second Primary Cancer Risk Among Kidney Cancer Patients in Korea: A Population-Based Cohort Study
Jae Young Joung, Whi-An Kwon, Jiwon Lim, Chang-Mo Oh, Kyu-Won Jung, Sung Han Kim, Ho Kyung Seo, Weon Seo Park, Jinsoo Chung, Kang Hyun Lee, Young-Joo Won
Received November 16, 2016     Accepted April 14, 2017     Published online April 19, 2017     DOI: https://doi.org/10.4143/crt.2016.543    
Clinical Outcomes of Proton Beam Therapy for Choroidal Melanoma at a Single Institute in Korea
Tae Wan Kim, Euncheol Choi, Jeonghoon Park, Dong-ho Shin, Su Kyung Jung, Susie Seok, Kwan Ho Cho, Joo-Young Kim, Dae Yong Kim, Tae Hyun Kim, Yang Kwon Suh, Yeon Joo Kim, Sung Ho Moon
Received February 9, 2017     Accepted April 17, 2017     Published online April 19, 2017     DOI: https://doi.org/10.4143/crt.2017.070    
A National Study of Survival Trends and Conditional Survival in Nasopharyngeal Carcinoma: Analysis of the National Population-Based Surveillance Epidemiology and End Results Registry
Jia-Wei Lv, Xiao-Dan Huang, Yu-Pei Chen, Guan-Qun Zhou, Ling-Long Tang, Yan-Ping Mao, Wen-Fei Li, Ai-Hua Lin, Jun Ma, Ying Sun
Received November 17, 2016     Accepted April 17, 2017     Published online April 19, 2017     DOI: https://doi.org/10.4143/crt.2016.544    
No Association of Positive Superficial and/or Deep Margins with Local Recurrence in Invasive Breast Cancer Treated with Breast-Conserving Surgery
Tae In Yoon, Jong Won Lee, Sae Byul Lee, Guiyun Sohn, Jisun Kim, Il Young Chung, Hee Jeong Kim, Beom Seok Ko, Byung Ho Son, Gyungyub Gong, Sung-Bae Kim, Su Ssan Kim, Seung Do Ahn, Minsung Chung, Sei Hyun Ahn
Received January 23, 2017     Accepted April 11, 2017     Published online April 14, 2017     DOI: https://doi.org/10.4143/crt.2017.041    
Selection Criteria for Active Surveillance of Patients with Prostate Cancer in Korea: A Multicenter Analysis of Pathology after Radical Prostatectomy
Chang Wook Jeong, Sung Kyu Hong, Seok Soo Byun, Seong Soo Jeon, Seong Il Seo, Hyun Moo Lee, Hanjong Ahn, Dong Deuk Kwon, Hong Koo Ha, Tae Gyun Kwon, Jae Seung Chung, Cheol Kwak, Hyung Jin Kim
Received October 5, 2016     Accepted April 6, 2017     Published online April 14, 2017     DOI: https://doi.org/10.4143/crt.2016.477    
Korean Cancer Patients’ Awareness of Clinical Trials, Perceptions on the Benefit and Willingness to Participate
Yoojoo Lim, Jee Min Lim, Won Jae Jeong, Kyung-Hun Lee, Bhumsuk Keam, Tae-Yong Kim, Tae Min Kim, Sae-Won Han, Do Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Seock-Ah Im
Received August 29, 2016     Accepted January 3, 2017     Published online April 7, 2017     DOI: https://doi.org/10.4143/crt.2016.413    
Original Article
Comparison of Ion Personal Genome Machine Platforms for the Detection of Variants in BRCA1 and BRCA2
Sang Mee Hwang, Ki Chan Lee, Min Seob Lee, Kyoung Un Park
Received February 1, 2017     Accepted April 3, 2017     Published online April 7, 2017     DOI: https://doi.org/10.4143/crt.2017.062    
Original Articles
The Prognostic Value of Treatment-Related Lymphopenia in Nasopharyngeal Carcinoma Patients
Li-Ting Liu, Qiu-Yan Chen, Lin-Quan Tang, Shan-Shan Guo, Ling Guo, Hao-Yuan Mo, Ming-Yuan Chen, Chong Zhao, Xiang Guo, Chao-Nan Qian, Mu-Sheng Zeng, Jin-Xin Bei, Jing Tan, Shuai Chen, Ming-Huang Hong, Jian-Yong Shao, Ying Sun, Jun Ma, Hai-Qiang Mai
Received December 18, 2016     Accepted February 11, 2017     Published online April 5, 2017     DOI: https://doi.org/10.4143/crt.2016.595    
Gemcitabine and Docetaxel Combination for Advanced Soft Tissue Sarcoma: A Nationwide Retrospective Study
Yunjung Choi, Mi Sun Yun, Sang Hee Lim, Jeeyun Lee, Jin-Hee Ahn, Yu Jung Kim, Kyong Hwa Park, Young Suk Park, Ho Yeong Lim, Hyonggin An, Dong-Churl Suh, Yeul Hong Kim
Received November 10, 2016     Accepted March 15, 2017     Published online March 30, 2017     DOI: https://doi.org/10.4143/crt.2016.535    
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