Search
- Page Path
-
HOME
> Search
Original Articles
-
A Clinical Analysis of Primary Small Bowel Cancer
-
Ki Sun Kil, Jin Sun Bae
-
J Korean Cancer Assoc. 1997;29(5):899-905.
-
-
-
Abstract
PDF
- PURPOSE
Primary small bowel cancer is rare. In many cases, the diagnosis is difficult especially in jejunum and ileum, confirmed in advanced state with poor prognosis. This study was intended to clarify the characteristics of primary small bowel cancer.
MATERIAL AND METHOD: We have reviewed 24 patients with primary small bowel cancer that have been operated at the Department of Surgery, hospital from Jan. 1990 until Dec.
1996. The clinical feature, diagnostic method, location and histologic finding of tumor, prognosis were analyzed.
RESULTS
1. The ratio of male to female was 1:1.18. The mean age was 53 years and the most prevalent age group was 6th decade (13 cases, 54.1%). 2. The most common primary site was jejunum (9 cases), followed by duodenum (8 cases) and ileum (7 cases). Leiomyosarcoma occurred most frequently in jejunum, adenocarcinoma in duodenum, and lymphoma in ileum.
3. The most common symptom was abdominal pain (66.7%), followed by anemia (54.2%), palpable mass (50%). 4. The accuracy rate of preoperative diagnosis or suspicion was 45.8%, and diagnostic measures were endoscopy in duodenum, small bowel series and/or abdominal CT. in jejunum and ileum. 5. Curative resection was performed in 14 cases (58.3%), and the cancer in which palliative resection was undertaken most frequently was leiomyosarcoma. 6. The mean follow-up period of 23 cases except 1 was 33 months, during this time 9 cases were dead, of whom 5 cases had leiomyosarcoma.
CONCLUSION
Frequently, small bowel cancer is difficult in diagnosis, confirmed in late stage. High degree of suspicion and more endeavor to discover it is important and needed to bring a better result.
-
A Clinical Analysis of Primary Small Bowel Cancer
-
Sang Yong Yun, Ik Jin Yun, Se Hwan Han, Jae Gahb Park, Kuhn Uk Lee, Kuk Jin Choe
-
J Korean Cancer Assoc. 1996;28(1):72-78.
-
-
-
Abstract
PDF
- Though small intestine accounts for 75% in the length and 90% in the mucosal surface of the gastrointestinal tract, primary small bowel cancer is relatively rare. So characteristics of smal1 bowel cancer are not known precisely. We analyzed 63 cases of the primary small bowel cancer(except ampulla of Vater cancer) that were operated at the department of surgery, Seoul National University Hospital from 1980 to 1994. The clinical features, diagnostic method, tumor location, histologic findings, preoperative diagnotic accuracy and type of operation were analyzed. The results were as follows; 1) There were 37 men and 26 women, ranging from 24 years to 95 years of age. The most prevalent age group was 6th decade(25 cases, 40%). 2) There were 28 adenocarcinomas, 18 lymphomas, 13 leiomyosarcomas, 3 carcinoid tumors and I liposarcoma, 3) The primary sites were the duodenum in 26, jeiunum in 13, ileum in 25 patients. The adenocarcinoma ocurred most frequently in duodenum(24/28,86%), lymphoma in ileum(17/18, 94%) and leiomyosarcoma in the jejunum(13/19,77%) 4) The most frequent chief complaint was abdominal pain(53%) followed by hemorrhage (21%), abdominal mass, obstructive symptom, jaundice and so on. 5) The average duration of symptoms of adenocarcinoma was 6 months, lymphoma 4 months, leiomyosarcoma 9 months and carcinoid 3 months 6) The correct diagnosis was made preoperatively in 59% of cases. Preoperative diagnosis of duodenal cancer was made by UGI series and/or endoscopy(79%). Jejunal and ileal cancers were diagnosed preoperatively by small bowel series and/or abdominal CT(44%). 7) Curative resection was possible in 54%. Palliative resection, bypass surgery, open biopsy were performed in 46% cases because of the distant metastasis or irresectability. 8) The median duration of recurrence,among the recurrent cases was 15 months. Adenocarcinoma had the poorer prognosis. Median disease free survivals in adenocarcinoma were 12.6 months, lymphoma 16 months and leiomyosarcoma 27 months. Median disease free survivals in curative resection group was 26 manths compared to 10 months in palliation group. We concluded that the most important factor determining the prognosis of small bowel cancer patient may be initial stage of cancer at the time of the first diagnosis.
TOP