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Review Article
Prognostication of the Last Days of Life
Masanori Mori, Tatsuya Morita, Eduardo Bruera, David Hui
Cancer Res Treat. 2022;54(3):631-643.   Published online March 30, 2022
DOI: https://doi.org/10.4143/crt.2021.1573
AbstractAbstract PDFPubReaderePub
Accurate prediction of impending death (i.e., last few days of life) is essential for terminally-ill cancer patients and their families. International guidelines state that clinicians should identify patients with impending death, communicate the prognosis with patients and families, help them with their end-of-life decision-making, and provide sufficient symptom palliation. Over the past decade, several national and international studies have been conducted that systematically investigated signs and symptoms of impending death as well as how to communicate such a prognosis effectively with patients and families. In this article, we summarize the current evidence on prognostication and communication regarding the last days of life of patients with cancer, and future directions of clinical research.

Citations

Citations to this article as recorded by  
  • Prevalence of Triggers and Patient Harm Identified by Global Trigger Tool in Specialized Palliative Care
    Olav Magnus S. Fredheim, Espen Klingenberg, Anne Karin Lindahl
    Journal of Palliative Medicine.2024; 27(6): 742.     CrossRef
  • Uso degli antibiotici nel fine vita
    Matteo Moroni, Massimo Melo, Raffaella Antonione, Massimo Fantoni, Roberto Luzzati, Massimiliano Lanzafame, Rita Murri, Fabio Gilioli, Francesco Dentali, Dario Manfellotto, Biancamaria Fraccaro, Luigi Patil
    Italian Journal of Medicine.2024;[Epub]     CrossRef
  • Using Performance Status to Identify Risk of Acute Care Transfer in Inpatient Cancer Rehabilitation
    Keara McNair, Amanda Botticello, Michael D. Stubblefield
    Archives of Physical Medicine and Rehabilitation.2024; 105(5): 947.     CrossRef
  • Indian Society of Critical Care Medicine and Indian Association of Palliative Care Expert Consensus and Position Statements for End-of-life and Palliative Care in the Intensive Care Unit
    Sudeep Gupta, Arun Kumar, Roli Mathur, Roop Gursahani, Sushma Bhatnagar, Jayita Deodhar, Prashant Nasa, Raj Kumar Mani, Naveen Salins, Priyadarshini Kulkarni, Srinagesh Simha, Jigeeshu V Divatia, Sheila N Myatra, Dhvani Mehta, Rajani S Bhat, Savita Butola
    Indian Journal of Critical Care Medicine.2024; 28(3): 200.     CrossRef
  • Comparison of Prognostic Abilities of Palliative Prognostic Index, Laboratory Prognostic Score, and Palliative Prognostic Score
    Norihiro Yuasa, Natsuko Kawai, Junichi Takamizawa
    Journal of Pain and Symptom Management.2024; 68(2): 153.     CrossRef
  • Management of Infections in Palliative Care Patients at the End-of-Life and Active Process of Death: A Brazilian Retrospective Study
    Isabela Fernandes de Aguiar Tonetto, Angelita Maria Stabile, Dieyeni Yuki Kobayasi, Rita de Cássia Quaglio, Ana Carolina de Souza, Fabiana Bolela
    Palliative Medicine Reports.2024; 5(1): 324.     CrossRef
  • Case report: Poor prognosis or poor prognostication?
    Jacqueline Tschanz, Rida Khan, Eduardo Bruera
    Palliative and Supportive Care.2024; : 1.     CrossRef
  • Effectiveness of palliative postural care in alleviating pain and psychological distress in terminal cancer patients
    Jia Fu, Yu Liu, Mei Zhang, Lili He
    Asian Journal of Surgery.2024;[Epub]     CrossRef
  • Fatores Associados ao Karnofsky Performance Status e sua Trajetória no Último Mês de Vida em Pacientes com Câncer Terminal
    Andrezza Helena Regadas Muniz, Karla Santos da Costa Rosa, Juliana Miranda Dutra de Resende, Simone Garruth dos Santos Machado Sampaio, Livia Costa de Oliveira
    Revista Brasileira de Cancerologia.2023;[Epub]     CrossRef
  • ‘It’s not just about me’: a qualitative study of couples’ narratives about home death when one of the partners is dying of cancer
    Margareta Aurén-Møkleby, Lisbeth Thoresen, Anne Marit Mengshoel, Kari N. Solbrække, Gunvor Aasbø
    Palliative Care and Social Practice.2023;[Epub]     CrossRef
  • Appetite and its association with mortality in patients with advanced cancer – a Post-hoc Analysis from the Palliative D-study
    Charlotte Goodrose-Flores, Stephanie E. Bonn, Caritha Klasson, Maria Helde Frankling, Ylva Trolle Lagerros, Linda Björkhem-Bergman
    BMC Palliative Care.2023;[Epub]     CrossRef
  • Overtreatment in end-of-life care: how can we do better?
    Linda Björkhem-Bergman
    Acta Oncologica.2022; 61(12): 1435.     CrossRef
  • 9,825 View
  • 603 Download
  • 10 Web of Science
  • 12 Crossref
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Original Article
Experiences and Opinions Related to End-of-Life Discussion: From Oncologists' and Resident Physicians' Perspectives
Su-Jin Koh, Shinmi Kim, JinShil Kim, Bhumsuk Keam, Dae Seog Heo, Kyung Hee Lee, Bong-Seog Kim, Jee Hyun Kim, Hye Jung Chang, Sun Kyung Baek
Cancer Res Treat. 2018;50(2):614-623.   Published online July 3, 2017
DOI: https://doi.org/10.4143/crt.2016.446
AbstractAbstract PDFPubReaderePub
Purpose
The aims of this study were to explore how oncologists and resident physicians practice end-of-life (EOL) discussions and to solicit their opinions on EOL discussions as a means to improve the quality of EOL care.
Materials and Methods
A survey questionnaire was developed to explore the experiences and opinions about EOL discussions among oncologists and residents. Descriptive statistics, the t test, and the chisquare test were performed for the analyses.
Results
A total of 147 oncologists and 229 residents participated in this study. The study respondents reported diverse definitions of “terminal state,” and mostrespondents tried to disclose the patient’s condition to the patient and/or family members. Both groups were involved in EOL care discussions, with a rather low satisfaction level (57.82/100). The best timing to initiate discussionwas consideredwhen metastasis or disease recurrence occurred orwhen withdrawal of chemotherapy was anticipated. Furthermore, the study respondents suggested that patients and their family members should be included in the EOL discussion. Medical, legal, and ethical knowledge and communication difficulties along with practical issues were revealed as barriers and facilitators for EOL discussion.
Conclusion
This study explored various perspectives of oncologists and resident physicians for EOL discussion. Since the Life-Sustaining-Treatment Decision-Making Act will be implemented shortly in Korea, now is the time for oncologists and residents to prepare themselves by acquiring legal knowledge and communication skills. To achieve this, education, training, and clinical tools for healthcare professionals are required.

Citations

Citations to this article as recorded by  
  • Physicians are over optimistic in recognizing inpatients’ survival and palliative care needs: a large-scale multi-center study in Taiwan
    C -M Huang, S -J Huang, T -Y Wu, Y -C Chen, S -H Hsiao, D Chu
    QJM: An International Journal of Medicine.2024; 117(3): 195.     CrossRef
  • The quality of dying and death of patients with cancer from Shanghai in China from the perspective of healthcare providers: A cross-sectional study
    Jiawei Min, Peihao Liu, Kaifeng Xiao, Zhe Huang, Xiaobin Lai
    International Journal of Nursing Sciences.2024; 11(2): 179.     CrossRef
  • Issues and implications of the life-sustaining treatment decision act: comparing the data from the survey and clinical data of inpatients at the end-of-life process
    Eunjeong Song, Dongsoon Shin, Jooseon Lee, Seonyoung Yun, Minjeong Eom, Suhee Oh, Heejung Lee, Jiwan Lee, Rhayun Song
    BMC Medical Ethics.2024;[Epub]     CrossRef
  • Experience and perspectives of end-of-life care discussion and physician orders for life-sustaining treatment of Korea (POLST-K): a cross-sectional study
    Hyeon-Su Im, Insook Lee, Shinmi Kim, Jong Soo Lee, Ju-Hee Kim, Jae Young Moon, Byung Kyu Park, Kyung Hee Lee, Myung Ah Lee, Sanghoon Han, Yoonki Hong, Hyeyeoung Kim, Jaekyung Cheon, Su-Jin Koh
    BMC Medical Ethics.2023;[Epub]     CrossRef
  • Barriers and facilitators that hospital clinicians perceive to discuss the personal values, wishes, and needs of patients in palliative care: a mixed-methods systematic review
    Sita de Vries, Mary-Joanne Verhoef, Sigrid Cornelia Johanna Maria Vervoort, Yvette Milene van der Linden, Saskia Cornelia Constantia Maria Teunissen, Everlien de Graaf
    Palliative Care and Social Practice.2023;[Epub]     CrossRef
  • Association Among End-Of-Life Discussions, Cancer Patients’ Quality of Life at End of Life, and Bereaved Families’ Mental Health
    Yoko Hayashi, Kazuki Sato, Masahiro Ogawa, Yoshiro Taguchi, Hisashi Wakayama, Aya Nishioka, Chikako Nakamura, Kaoru Murota, Ayumi Sugimura, Shoko Ando
    American Journal of Hospice and Palliative Medicine®.2022; 39(9): 1071.     CrossRef
  • Difficulties Facing Junior Physicians and Solutions Toward Delivering End-of-Life Care for Patients with Cancer: A Nationwide Survey in Japan
    Soichiro Okamoto, Yu Uneno, Natsuki Kawashima, Shunsuke Oyamada, Yusuke Hiratsuka, Keita Tagami, Manabu Muto, Tatsuya Morita
    Palliative Medicine Reports.2022; 3(1): 255.     CrossRef
  • The silent transition from curative to palliative treatment: a qualitative study about cancer patients’ perceptions of end-of-life discussions with oncologists
    A. Kitta, A. Hagin, M. Unseld, F. Adamidis, T. Diendorfer, E. K. Masel, K. Kirchheiner
    Supportive Care in Cancer.2021; 29(5): 2405.     CrossRef
  • Advance Care Planning in Asia: A Systematic Narrative Review of Healthcare Professionals’ Knowledge, Attitude, and Experience
    Diah Martina, Cheng-Pei Lin, Martina S. Kristanti, Wichor M. Bramer, Masanori Mori, Ida J. Korfage, Agnes van der Heide, Carin C.D. van der Rijt, Judith A.C. Rietjens
    Journal of the American Medical Directors Association.2021; 22(2): 349.e1.     CrossRef
  • Difficulties Doctors Experience during Life-Sustaining Treatment Discussion after Enactment of the Life-Sustaining Treatment Decisions Act: A Cross-Sectional Study
    Shin Hye Yoo, Wonho Choi, Yejin Kim, Min Sun Kim, Hye Yoon Park, Bhumsuk Keam, Dae Seog Heo
    Cancer Research and Treatment.2021; 53(2): 584.     CrossRef
  • Changes in decision-making process for life-sustaining treatment in patients with advanced cancer after the life-sustaining treatment decisions-making act
    Hyeyeong Kim, Hyeon-Su Im, Kyong Og Lee, Young Joo Min, Jae-Cheol Jo, Yunsuk Choi, Yoo Jin Lee, Daseul Kang, Changyoung Kim, Su-Jin Koh, Jaekyung Cheon
    BMC Palliative Care.2021;[Epub]     CrossRef
  • Act on Decisions on Life-Sustaining Treatment and Timing of Referral to Hospice
    Han-na Ju, Seung Hun Lee, Yun-Jin Kim, Sang-Yeoup Lee, Jeong-Gyu Lee, Yu-Hyeon Yi, Young-Hye Cho, Young-Jin Tak, Hye-Rim Hwang, Eun-Ju Park, Young-In Lee
    Korean Journal of Family Practice.2021; 11(5): 331.     CrossRef
  • Nature of Discussions about Systemic Therapy Discontinuation or Hospice among Patients, Families, and Palliative Care Clinicians during Care for Incurable Cancer: A Qualitative Study
    Lara Traeger, Chelsea Rapoport, Emily Wright, Areej El-Jawahri, Joseph A. Greer, Elyse R. Park, Vicki A. Jackson, Jennifer S. Temel
    Journal of Palliative Medicine.2020; 23(4): 542.     CrossRef
  • Implication of the Life-Sustaining Treatment Decisions Act on End-of-Life Care for Korean Terminal Patients
    Jung Sun Kim, Shin Hye Yoo, Wonho Choi, Yejin Kim, Jinui Hong, Min Sun Kim, Hye Yoon Park, Bhumsuk Keam, Dae Seog Heo
    Cancer Research and Treatment.2020; 52(3): 917.     CrossRef
  • Advance care planning in Asian culture
    Shao-Yi Cheng, Cheng-Pei Lin, Helen Yue-lai Chan, Diah Martina, Masanori Mori, Sun-Hyun Kim, Raymond Ng
    Japanese Journal of Clinical Oncology.2020; 50(9): 976.     CrossRef
  • Differences in perspectives of pediatricians on advance care planning: a cross-sectional survey
    In Gyu Song, Sung Han Kang, Min Sun Kim, Cho Hee Kim, Yi Ji Moon, Jung Lee
    BMC Palliative Care.2020;[Epub]     CrossRef
  • Feasibility of a team based prognosis and treatment goal discussion (T-PAT) with women diagnosed with advanced breast cancer
    Mary M. Step, Gretchen A. Ferber, Catherine Downs-Holmes, Paula Silverman
    Patient Education and Counseling.2019; 102(1): 77.     CrossRef
  • Attitudes of the General Public, Cancer Patients, Family Caregivers, and Physicians Toward Advance Care Planning: A Nationwide Survey Before the Enforcement of the Life-Sustaining Treatment Decision-Making Act
    Hye Yoon Park, Young Ae Kim, Jin-Ah Sim, Jihye Lee, Hyewon Ryu, Jung Lim Lee, Chi Hoon Maeng, Jung Hye Kwon, Yu Jung Kim, Eun Mi Nam, Hyun-Jeong Shim, Eun-Kee Song, Kyung Hae Jung, Eun Joo Kang, Jung Hun Kang, Young Ho Yun
    Journal of Pain and Symptom Management.2019; 57(4): 774.     CrossRef
  • Family-clinician communication in the ICU and its relationship to psychological distress of family members: A cross-sectional study
    Minjeong Jo, Mi-Kyung Song, George J. Knafl, Linda Beeber, Yang-Sook Yoo, Marcia Van Riper
    International Journal of Nursing Studies.2019; 95: 34.     CrossRef
  • Implementation of Antimicrobial Stewardship Programs in End-of-Life Care
    Ki Tae Kwon
    Infection & Chemotherapy.2019; 51(2): 89.     CrossRef
  • Facilitators and Barriers to Oncologists’ Conduct of Goals of Care Conversations
    Dena Schulman-Green, Jenny J. Lin, Cardinale B. Smith, Shelli Feder, Nina A. Bickell
    Journal of Palliative Care.2018; 33(3): 143.     CrossRef
  • Clinical characteristics and survival outcomes of terminally ill patients undergoing withdrawal of mechanical ventilation
    Yu-Shin Hung, Shu-Hui Lee, Chia-Yen Hung, Chao-Hui Wang, Chen-Yi Kao, Hung-Ming Wang, Wen-Chi Chou
    Journal of the Formosan Medical Association.2017;[Epub]     CrossRef
  • 9,757 View
  • 267 Download
  • 22 Web of Science
  • 22 Crossref
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