Cancer Research and Treatment

The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5‐fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway

Anna Han, Taorui Liu, Pan Du, Mengying Wang, Jiajing Liu, Liyan Chen

Molecular Carcinogenesis.2024; 63(4): 688. CrossRef

Targeted and Immunotherapy Approaches in HER2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma: A New Era

Maluki Radford, Hassan Abushukair, Stijn Hentzen, Ludimila Cavalcante, Anwaar Saeed

Journal of Immunotherapy and Precision Oncology.2023; 6(3): 150. CrossRef

Resistance mechanisms to HER2-targeted therapy in gastroesophageal adenocarcinoma: A systematic review

Dionne Blangé, Charlotte I. Stroes, Sarah Derks, Maarten F. Bijlsma, Hanneke W.M. van Laarhoven

Cancer Treatment Reviews.2022; 108: 102418. CrossRef

The FOXO family of transcription factors: key molecular players in gastric cancer

Ying Liu, Xiang Ao, Yi Jia, Xiaoge Li, Yu Wang, Jianxun Wang

Journal of Molecular Medicine.2022; 100(7): 997. CrossRef

VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF-β/ERK/RSK2 signaling

Joo-Young Im, Da-Mi Kim, Hyunkyung Park, Mi-Jung Kang, Da-Yoon Kim, Kwan Young Chang, Bo-Kyung Kim, Misun Won

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.2021; 1868(1): 118892. CrossRef

The efficacy and safety of onartuzumab in patients with solid cancers: A meta-analysis of randomized trials

BumJun Kim, Dalyong Kim, JungHan Kim, HyeongSu Kim, HyunJoo Jang

Indian Journal of Cancer.2021; 58(2): 232. CrossRef

Yinxing Zhu, Xuedan Zhu, Xiaowei Wei, Cuiju Tang, Wenwen Zhang

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.2021; 1876(1): 188549. CrossRef

Current therapeutic options for gastric adenocarcinoma

C.R. Akshatha, Smitha Bhat, R. Sindhu, Dharini Shashank, Sarana Rose Sommano, Wanaporn Tapingkae, Ratchadawan Cheewangkoon, Shashanka K. Prasad

Saudi Journal of Biological Sciences.2021; 28(9): 5371. CrossRef

Diverse roles of FOXO family members in gastric cancer

Yu-Han Chen, Chun-Lan Li, Wen-Jia Chen, Jing Liu, Hua-Tao Wu

World Journal of Gastrointestinal Oncology.2021; 13(10): 1367. CrossRef

Overcoming resistance to targeted therapy using MET inhibitors in solid cancers: evidence from preclinical and clinical studies

Nehad M. Ayoub, Dalia R. Ibrahim, Amer E. Alkhalifa

Caveolin-1 Promotes Chemoresistance of Gastric Cancer Cells to Cisplatin by Activating WNT/β-Catenin Pathway

Xi Wang, Bin Lu, Chunyan Dai, Yufei Fu, Ke Hao, Bing Zhao, Zhe Chen, Li Fu

Machine Learning-Guided Prediction of Antigen-Reactive In Silico Clonotypes Based on Changes in Clonal Abundance through Bio-Panning

Duck Kyun Yoo, Seung Ryul Lee, Yushin Jung, Haejun Han, Hwa Kyoung Lee, Jerome Han, Soohyun Kim, Jisu Chae, Taehoon Ryu, Junho Chung

FOXO transcription factor family in cancer and metastasis

Cancer and Metastasis Reviews.2020; 39(3): 681. CrossRef

In vitro and in vivo Anti-Tumor Effects of Pan-HER Inhibitor Varlitinib on Cholangiocarcinoma Cell Lines

Hasaya Dokduang, Wassana Jamnongkarn, Bundit Promraksa, Manida Suksawat, Sureerat Padthaisong, Malinee Thanee, Jutarop Phetcharaburanin, Nisana Namwat, Sakkarn Sangkhamanon, Attapol Titapun, Narong Khuntikeo, Poramate Klanrit, Watcharin Loilome

Drug Design, Development and Therapy.2020; Volume 14: 2319. CrossRef

MiR-27a promotes EMT in ovarian cancer through active Wnt/

Li-Ya Zhang, Yuan Chen, Jue Jia, Xi Zhu, Yan He, Li-Ming Wu

Members of FOX family could be drug targets of cancers

Jinhua Wang, Wan Li, Ying Zhao, De Kang, Weiqi Fu, Xiangjin Zheng, Xiaocong Pang, Guanhua Du

Pharmacology & Therapeutics.2018; 181: 183. CrossRef

FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models

Cristina Corno, Simone Stucchi, Michelandrea De Cesare, Nives Carenini, Serena Stamatakos, Emilio Ciusani, Lucia Minoli, Eugenio Scanziani, Christian Argueta, Yosef Landesman, Nadia Zaffaroni, Laura Gatti, Paola Perego

Biochemical Pharmacology.2018; 147: 93. CrossRef

Nuclear division cycle 80 promotes malignant progression and predicts clinical outcome in colorectal cancer

Xuebing Yan, Linsheng Huang, Liguo Liu, Huanlong Qin, Zhenshun Song

Systems analysis of key genes and pathways in the progression of hepatocellular carcinoma

Yu-Kui Shang, Fanni Li, Yi Zhang, Ze-Kun Liu, Zi-Ling Wang, Huijie Bian, Zhi-Nan Chen

The Dominant Role of Forkhead Box Proteins in Cancer

Duc-Hiep Bach, Nguyen Long, Thi-Thu-Trang Luu, Nguyen Anh, Sung Kwon, Sang Lee

International Journal of Molecular Sciences.2018; 19(10): 3279. CrossRef

HSP90 inhibitor, AUY922, debilitates intrinsic and acquired lapatinib-resistant HER2-positive gastric cancer cells

Kang-Seo Park, Yong Sang Hong, Junyoung Choi, Shinkyo Yoon, Jihoon Kang, Deokhoon Kim, Kang-Pa Lee, Hyeon-Su Im, Chang Hoon Lee, Seyoung Seo, Sang-We Kim, Dae Ho Lee, Sook Ryun Park

FOXO1 reduces tumorsphere formation capacity and has crosstalk with LGR5 signaling in gastric cancer cells

Yiseul Choi, Jinju Park, Young San Ko, Younghoon Kim, Jung-Soo Pyo, Bo Gun Jang, Min A Kim, Jae-Seon Lee, Mee Soo Chang, Byung Lan Lee

Biochemical and Biophysical Research Communication.2017; 493(3): 1349. CrossRef

Trifluoperazine Activates FOXO1-Related Signals to Inhibit Tumor Growth in Hepatocellular Carcinoma

Jingwen Jiang, Zhongxi Huang, Xuewu Chen, Rongcheng Luo, Hongbin Cai, Hairu Wang, Hui Zhang, Tao Sun, Yunfang Zhang

DNA and Cell Biology.2017; 36(10): 813. CrossRef