Cancer Research and Treatment

WP1066, a small molecule inhibitor of STAT3, chemosensitizes paclitaxel-resistant ovarian cancer cells to paclitaxel by simultaneously inhibiting the activity of STAT3 and the interaction of STAT3 with Stathmin

Jun Yang, Nanjing Li, Xinyu Zhao, Wenhao Guo, Yang Wu, Chunlai Nie, Zhu Yuan

Biochemical Pharmacology.2024; 221: 116040. CrossRef

Impact of Obesity and Lysosomal Dysfunction on Chemoresistance in Ovarian Cancer

Comparison of Interleukin-6 with Other Markers in Diagnosis of Ovarian Cancer

Magdalena Bizoń, Zofia Awiżeń-Panufnik, Włodzimierz Sawicki

Journal of Personalized Medicine.2023; 13(6): 980. CrossRef

The potential role of interleukins and interferons in ovarian cancer

Huldani Huldani, Sana Abdul-Jabbar Ali, F. Al-dolaimy, Ahmed Hjazi, Nikolenko Denis Andreevich, Khulood H. Oudaha, Abbas F. Almulla, Ali Alsaalamy, Shamam Kareem Oudah, Yasser Fakri Mustafa

ARF6 promotes hepatocellular carcinoma proliferation through activating STAT3 signaling

Yabing Hu, Yongchu Huang, Xiaohang Xie, Longshan Li, Yong Zhang, Xiaochao Zhang

Cancer Cell International.2023;[Epub] CrossRef

M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation

Chunxu Lv, Shutong Li, Jingjing Zhao, Pishan Yang, Chengzhe Yang

Regulatory Role of the Adipose Microenvironment on Ovarian Cancer Progression

Hussein Chehade, Roslyn Tedja, Harry Ramos, Tejeshwar Singh Bawa, Nicholas Adzibolosu, Radhika Gogoi, Gil Mor, Ayesha B. Alvero

The effect of obesity on adipose-derived stromal cells and adipose tissue and their impact on cancer

Bruce A. Bunnell, Elizabeth C. Martin, Margarite D. Matossian, Courtney K. Brock, Khoa Nguyen, Bridgette Collins-Burow, Matthew E. Burow

Cancer and Metastasis Reviews.2022; 41(3): 549. CrossRef

The role of IL-6/JAK2/STAT3 signaling pathway in cancers

Adaptation of metabolism to multicellular aggregation, hypoxia and obese stromal cell incorporation as potential measure of survival of ovarian metastases

Stephanie L.E. Compton, Emily S. Pyne, Lu Liu, Jack Guinan, Amanda A. Shea, Joseph P. Grieco, Madlyn I. Frisard, Eva M. Schmelz

Experimental Cell Research.2021; 399(1): 112397. CrossRef

Perirenal Adipose Tissue—Current Knowledge and Future Opportunities

Adriana Grigoraș, Raluca Anca Balan, Irina-Draga Căruntu, Simona Eliza Giușcă, Ludmila Lozneanu, Roxana Elena Avadanei, Andreea Rusu, Laura Adriana Riscanu, Cornelia Amalinei

Journal of Clinical Medicine.2021; 10(6): 1291. CrossRef

Mesenchymal Stem Cells in Adipose Tissue and Extracellular Vesicles in Ovarian Cancer Patients: A Bridge toward Metastatic Diffusion or a New Therapeutic Opportunity?

Gabriele Storti, Maria Giovanna Scioli, Bong-Sung Kim, Sonia Terriaca, Elena Fiorelli, Augusto Orlandi, Valerio Cervelli

Obesity Promotes Tumor Immune Evasion in Ovarian Cancer Through Increased Production of Myeloid-Derived Suppressor Cells via IL-6

Qiannan Yang, Bojun Yu, Jiuhong Kang, Ang Li, Jing Sun

Cancer Management and Research.2021; Volume 13: 7355. CrossRef

Impact of Computed Tomography-Based, Artificial Intelligence-Driven Volumetric Sarcopenia on Survival Outcomes in Early Cervical Cancer

Qingling Han, Se Ik Kim, Soon Ho Yoon, Taek Min Kim, Hyun-Cheol Kang, Hak Jae Kim, Jeong Yeon Cho, Jae-Weon Kim

The implication of IL-6 in the invasiveness and chemoresistance of ovarian cancer cells. Systematic review of its potential role as a biomarker in ovarian cancer patients

Izabela Szulc-Kielbik, Michal Kielbik, Marek Nowak, Magdalena Klink

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer.2021; 1876(2): 188639. CrossRef

A Role for Adipocytes and Adipose Stem Cells in the Breast Tumor Microenvironment and Regenerative Medicine

Courtney K. Brock, Katherine L. Hebert, Maria Artiles, Maryl K. Wright, Thomas Cheng, Gabrielle O. Windsor, Khoa Nguyen, Madlin S. Alzoubi, Bridgette M. Collins-Burow, Elizabeth C. Martin, Frank H. Lau, Bruce A. Bunnell, Matthew E. Burow

Dietary fats promote inflammation in Wistar rats as well as induce proliferation, invasion of SKOV3 ovarian cancer cells

Jafar Saeidi, Reza Motaghipur, Atefe Sepehrian, Mahnaz Mohtashami, Fatemeh Forooghi Nia, Ahmad Ghasemi

Journal of Food Biochemistry.2020;[Epub] CrossRef

Impact of CT-Determined Sarcopenia and Body Composition on Survival Outcome in Patients with Advanced-Stage High-Grade Serous Ovarian Carcinoma

Se Ik Kim, Taek Min Kim, Maria Lee, Hee Seung Kim, Hyun Hoon Chung, Jeong Yeon Cho, Yong Sang Song

Stomatin-like Protein 2 Promotes Tumor Cell Survival by Activating the JAK2-STAT3-PIM1 Pathway, Suggesting a Novel Therapy in CRC

Qiang Liu, Anqi Li, Lisha Wang, Wei He, Ling Zhao, Chao Wu, Shasha Lu, Xuanguang Ye, Huiyong Zhao, Xiaohan Shen, Xiuying Xiao, Zebing Liu

Molecular Therapy - Oncolytics.2020; 17: 169. CrossRef

Targeting kinases with thymoquinone: a molecular approach to cancer therapeutics

Syeda Samira Afrose, Md. Junaid, Yeasmin Akter, Mousumi Tania, Meiling Zheng, Md. Asaduzzaman Khan

Drug Discovery Today.2020; 25(12): 2294. CrossRef

Sarcopenia: Clinical implications in ovarian cancer, diagnosis, etiology, and management

Sports Medicine and Health Science.2020; 2(4): 202. CrossRef

Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth

Karen McLean, Lijun Tan, Danielle E. Bolland, Lan G. Coffman, Luke F. Peterson, Moshe Talpaz, Nouri Neamati, Ronald J. Buckanovich

Resveratrol as a Tumor-Suppressive Nutraceutical Modulating Tumor Microenvironment and Malignant Behaviors of Cancer

Youngjin Han, HyunA Jo, Jae Cho, Danny Dhanasekaran, Yong Song

International Journal of Molecular Sciences.2019; 20(4): 925. CrossRef

Adipose Stem Cells and Cancer: Concise Review

Rachel A. Sabol, Paulina Giacomelli, Adam Beighley, Bruce A. Bunnell

Mitochondrial fission causes cisplatin resistance under hypoxic conditions via ROS in ovarian cancer cells

Youngjin Han, Boyun Kim, Untack Cho, In Sil Park, Se Ik Kim, Danny N. Dhanasekaran, Benjamin K. Tsang, Yong Sang Song

Activation of STAT3 and STAT5 Signaling in Epithelial Ovarian Cancer Progression: Mechanism and Therapeutic Opportunity

Chin-Jui Wu, Vignesh Sundararajan, Bor-Ching Sheu, Ruby Yun-Ju Huang, Lin-Hung Wei

Pro‐inflammatory M1 macrophage enhances metastatic potential of ovarian cancer cells through NF‐κB activation

Untack Cho, Boyun Kim, Soochi Kim, Youngjin Han, Yong Sang Song

Molecular Carcinogenesis.2018; 57(2): 235. CrossRef

Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway

Xue Hu, Jingjing Ma, Vikash Vikash, Jiao Li, Dandan Wu, Ya Liu, Jixiang Zhang, Weiguo Dong

Digestive Diseases and Sciences.2018; 63(1): 126. CrossRef

Perirenal Adiposity is Associated With Lower Progression-Free Survival From Ovarian Cancer

Yan Zhang, Adriana M. Coletta, Pamela K. Allen, Aaroh M. Parikh, Matthes Cox-Mattin, Larissa A. Meyer, Charlotte C. Sun, Karen M. Basen-Engquist, Karen H. Lu, Ann H. Klopp

International Journal of Gynecological Cancer.2018; 28(2): 285. CrossRef

Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer

Sanhong Li, Jilai Tian, Hongming Zhang, Shoubing Zhou, Xiyong Wang, Lei Zhang, Jiapeng Yang, Zhigang Zhang, Zhenling Ji

Role of the body mass index in the genesis of ascites in ovarian cancer: a forensic case and review of the literature

Isabella Aquila, Pietrantonio Ricci, Alessandra Oliverio, Santo Gratteri

BMJ Case Reports.2018; 11(1): e226491. CrossRef

The mechanism of alopolysaccharide protecting ulceralive colitis

Hu Lin, Li Honglang, Li Weifeng, Chen Junmin, Yang Jiantao, Gu Junjing

Biomedicine & Pharmacotherapy.2017; 88: 145. CrossRef

CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression

Ming-Horng Tsai, Chiang-Wen Lee, Lee-Fen Hsu, Shu-Yu Li, Yao-Chang Chiang, Ming-Hsueh Lee, Chun-Han Chen, Hwey-Fang Liang, Jia-Mei How, Pey-Jium Chang, Ching-Mei Wu, I-Ta Lee

Gene expression profiles of human subcutaneous and visceral adipose‐derived stem cells

Boyun Kim, Boram Lee, Mi‐Kyung Kim, Seung Pyo Gong, Noh Hyun Park, Hyun Hoon Chung, Hee Seung Kim, Jae Hong No, Woong Yang Park, Ae Kyung Park, Jeong Mook Lim, Yong Sang Song

Cell Biochemistry and Function.2016; 34(8): 563. CrossRef